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    Pickens, SC

    Pickens, SC Commercial Real Estate for Lease

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    Renovated Retail Suite
    Updated: Aug 20
    Renovated Retail Suite

    309 East Main Street, Pickens, SC 29671

    $1,100/Mo
    700 sqft
    Approximately 700 sq ft of retail space
    Completely renovated in 2026
    Open‑concept floor plan with private bath
    Tall ceilings and abundant natural light
    Main Street frontage and visibility
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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 1 Active listings in Pickens, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 30 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Building Adjacent to Hospital
    Office Building Adjacent to Hospital

    201 Richard St, Easley, SC 29640

    Contact for pricing
    4,036 sqft

    Office space available near Prisma Health Baptist Easley Hospital, with repaving and restriping planned for the parking lot.

    View details
    Freestanding Specialty Property
    Freestanding Specialty Property

    106 N Pendleton Street, Easley, SC 29640

    $2,800/Mo

    Open-plan commercial space includes restrooms, kitchenette, storage, and dedicated accessible parking.

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    Retail Space on Highway 123
    Retail Space on Highway 123

    6811 Calhoun Memorial Hwy Ste A, Easley, SC 29640

    $16 SF/Yr

    Retail space in Easley's trade area with high visibility.

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    Warehouse Space
    Warehouse Space

    747 & 749 Black Snake Road, Easley, SC 29640

    Contact for pricing

    Warehouse space available for lease in Easley, South Carolina.

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    Similar Spaces for Sale in Pickens, SC

    Consider Similar Space for Sale. We found 30 Spaces matching your search parameters.

    Live-Work Property with Detached Shop
    Live-Work Property with Detached Shop

    155 Farrs Bridge Rd, Pickens, SC 29671

    $225,000
    1,500 sqft 0.47 AC lot

    Two-bedroom residence with a separate shop and covered area supports combined personal and commercial use.

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    Specialty Property with Metal Roof
    Specialty Property with Metal Roof

    141 City View Circle, Pickens, SC 29671

    $399,000
    0.57 AC lot

    Brick-and-metal-siding facility with central air, electric cooling, and natural-gas heating.

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    Commercial Land Near Retail
    Commercial Land Near Retail

    106 Roberts Drive, Pickens, SC 29671

    $570,000
    1.55 AC lot

    Commercial land with public water service near established apartments, retail, and restaurant uses.

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    Pastureland With Barn
    Pastureland With Barn

    1549 Midway Road, Pickens, SC 29671

    $662,560
    40.40 AC lot

    Agricultural acreage with pasture, utility connections, fencing, and an open-sided barn.

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    Office Building with Two Units
    Office Building with Two Units

    113 Court Street, Pickens, SC 29671

    $350,000
    0.16 AC lot

    Brick office property with distinctive wood detailing, flexible meeting areas, and a private courtyard adjoining the Pickens County Court House.

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    Commercial Land with Highway Frontage
    Commercial Land with Highway Frontage

    2663 Gentry Memorial Highway, Pickens, SC 29671

    $1,200,000
    3.24 AC lot

    Commercial land with public water and road frontage.

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    Office Building with Brick Courtyard
    Office Building with Brick Courtyard

    113 Court St, Pickens, SC 29671

    $350,000

    Two-unit office property with meeting space, private courtyard, and on-site parking.

    View details
    Agricultural Land with Large Pond
    Agricultural Land with Large Pond

    1240 Walhalla Highway, Pickens, SC 29671

    $1,100,000
    95.53 AC lot

    95.53-acre tract with public water, 1,701 feet of frontage, and a large pond.

    View details
    Main Street Storefronts
    Main Street Storefronts

    131 /133 W Main St, Pickens, SC 29671

    $350,000

    Three commercial spaces offer retail, service, or office use across Main and Irwin Streets.

    View details
    Tract Land with Year-Round Creek
    Tract Land with Year-Round Creek

    3371 Moorefield Memorial Highway, Pickens, SC 29671

    $449,000
    12.80 AC lot

    12.8-acre property with Hagood Branch forming a boundary, mature trees, open pasture, and a partially fenced layout.

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    Three-Space Storefront Property
    Three-Space Storefront Property

    131/133 W Main Street, Pickens, SC 29671

    $350,000

    Three commercial spaces offer options for retail, service, or office operations in a multi-space configuration.

    View details
    Agricultural Land Tracts
    Agricultural Land Tracts

    01 Hagood Mill Road, Pickens, SC 29671

    $179,000
    25.00 AC lot

    Five roughly 5-acre tracts are offered for sale, allowing room to build and support small-scale farm use.

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    Commercial Land Near Retail Center
    Commercial Land Near Retail Center

    106 Roberts Dr, Pickens, SC 29671

    $570,000

    Water and sewer are available at this commercial land property.

    View details
    Turnkey Flex Space Facility
    Turnkey Flex Space Facility

    141 City View Cir, Pickens, SC 29671

    $399,000

    Well-maintained facility offering ample space for a variety of community-focused uses with easy access to local amenities.

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    Farm with Public Water and Road Frontage
    Farm with Public Water and Road Frontage

    3573 Moorefield Memorial Highway, Pickens, SC 29671

    $1,200,000

    Unrestricted farm acreage with a two-bedroom farmhouse, barn and outbuildings, plus public water availability.

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    Commercial Land with Highway Frontage
    Commercial Land with Highway Frontage

    2663 Gentry Memorial Highway, Pickens, SC 29671

    $1,200,000

    Unzoned commercial land with frontage on Gentry Memorial Highway.

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    Pickens SC Land For Sale
    Pickens SC Land For Sale

    Mount Bethel Road, Pickens, SC 29671

    $299,900
    15.00 AC lot

    15 acre tract suitable for homesite or livestock pasture.

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    Oolenoy River Waterfront Land
    Oolenoy River Waterfront Land

    716 Sliding Rock Rd, Pickens, SC 29671

    $280,000

    Pasture property with an office-efficiency apartment, single-car garage, creek, and direct river setting.

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    Corporate-Backed NNN Retail Investment
    Corporate-Backed NNN Retail Investment

    204 HAMPTON AVE, Pickens, SC 29671

    Contact for pricing

    For-sale NNN retail asset offered with a corporate-backed lease structure per broker remarks.

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    6.23 Acres Land For Sale
    6.23 Acres Land For Sale

    00 Grant Road, Pickens, SC 29671

    $99,000
    271,379 sqft 6.23 AC lot

    ±6.23 unrestricted acres conveniently located just outside of Downtown Pickens

    View details
    Farm
    Farm

    0000 Moorefield Memorial Highway, Pickens, SC 29671

    $598,900

    Agricultural land / Farmland

    View details
    Farm
    Farm

    118 Harris Road, Pickens, SC 29671

    $2,400,671

    Agricultural land / Farmland

    View details
    Specialty Commercial Property
    Specialty Commercial Property

    129 Hiawatha Trl, Pickens, SC 29671

    Contact for pricing

    For-sale specialty commercial property located at 129 Hiawatha Trl in Pickens, SC.

    View details

    Pickens, SC Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Pickens, SC with 1 listings featured on our commercial real estate exchange. The current inventory includes 700 square feet of properties with an estimated lease value of $18.86.

    Estimated lease rates for Commercial real estate in Pickens, SC average $18.86 SF/Yr.
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