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    Depew, NY Office Spaces for Sale

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    Buffalo, NY Bowmansville, NY El Dorado Hills, CA
    32 results
    Prime Corner Commercial Opportunity
    $749,900
    2,877 SF
    Prime Corner Commercial Opportunity

    4734 Transit Road, Depew, NY 14043

    High-visibility corner property with retail, office, and residential potential.
    • Prime corner location at Transit Rd & French Rd with high visibility and traffic.
    • Versatile property suitable for retail, office, or mixed‑use development.
    • Upper level one‑bedroom apartment provides owner occupancy or rental income potential.
    • Functional main level layout with showroom, private showroom, office, and work area.
    • Ample parking and a detached 2‑car garage.
    Updated: May 27
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    Versatile Lancaster Commercial Building
    $460,000
    6,103 SF
    Versatile Lancaster Commercial Building

    3568 Walden Ave, Lancaster, NY 14086

    6,103 sq ft building with showroom, office, and basement.
    • High‑visibility location on Walden Ave, suitable for a variety of businesses.
    • Large 6,103 sq ft building with dynamic layout including showroom, office, conference room, and kitchenette.
    • Expansive basement with 10 ft ceilings and dual access, divisible into two units for income potential.
    • Ample parking with 28 dedicated spaces.
    • Recent updates: Roof, windows, and parking lot redone in 2021/2022, electrical repairs in 2024, and interior updates in 2025.
    Updated: Apr 24
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    Spacious Home with In-Law Suite
    $324,900
    1,937 SF
    Spacious Home with In-Law Suite

    Versatile 5-bedroom home with in-law suite and saltwater pool.

    500 Rowley Road, Depew, NY 14043

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    Mixed-Use Property in High-Traffic Area
    $439,900
    Mixed-Use Property in High-Traffic Area

    Mixed-use property with commercial space and residential apartments for sale.

    3284 Walden Ave, Lancaster, NY 14043

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    Inviting Office Space on Transit
    $1,100,000
    8,647 SF
    Inviting Office Space on Transit

    Contemporary office building with high visibility and ample parking.

    6199 Transit Rd, Depew, NY

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    Industrial Buildings and Modern Office
    Contact for pricing
    9,375 SF
    Industrial Buildings and Modern Office

    Two industrial buildings with a modern office and backup generator.

    5636 Transit Road, Depew, NY 14043

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    Flex Space Investment Opportunity
    $2,100,000
    31,500 SF
    Flex Space Investment Opportunity

    Flex space investment property with long-term tenants and zero vacancies.

    491 Erie St, Lancaster, NY 14086

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    Multi-Tenanted Building on Transit Road
    $750,000
    13,724 SF
    Multi-Tenanted Building on Transit Road

    Multi-tenanted building with office, warehouse, and apartment units for sale.

    5800 Transit Road, Depew, NY 14043

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    Renovated Office Building in Lancaster
    $500,000
    12,188 SF
    Renovated Office Building in Lancaster

    Extensively renovated office building with parking in historic village downtown.

    5400 Broadway, Lancaster, NY 14086

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    Transit Road Retail Opportunity
    $1,275,000
    Transit Road Retail Opportunity

    2.76-acre site with existing building in high-traffic area.

    6140 Transit Road, Depew, NY 14043

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    Versatile Multi-Use Office Building
    $1,599,000
    Versatile Multi-Use Office Building

    Well-maintained office building with expansion potential in a high-traffic location.

    6300 Transit Rd, Depew, NY 14043

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    Converted Office Building For Sale
    $299,777
    0.25 Acres
    Converted Office Building For Sale

    Office building with high visibility and easy access to highways.

    3517 Genesee St, Cheektowaga, NY 14225

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    Broadway Street Auto Shop Opportunity
    $275,000
    2,337 SF
    Broadway Street Auto Shop Opportunity

    Auto shop with detached home and high-visibility frontage.

    6526 Broadway St, Lancaster, NY

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    Two-Story Office Building For Sale
    $334,900
    3,850 SF
    Two-Story Office Building For Sale

    Two-story office building with income potential and on-site parking.

    5813 Transit, Depew, NY 14043

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    Lancaster Office Property on Acres
    $4,950,000
    60,000 SF
    Lancaster Office Property on Acres

    Two-story, 59,804 SF LEED Certified office on 119 acres.

    368 Pleasant View, Lancaster, NY 14086

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    Lancaster Office or Retail Opportunity
    $287,500
    Lancaster Office or Retail Opportunity

    1,600+/- SF office/retail space with high visibility and ample parking.

    5300 Broadway Street, Lancaster, NY 14086

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    High-Visibility Office Building on George Urban
    $279,900
    1,680 SF
    High-Visibility Office Building on George Urban

    Well-maintained 1,680 Sq Ft office building on George Urban Blvd.

    2478 George Urban Blvd, Depew, NY

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    Finished Office with Storage Garage
    $249,900
    Finished Office with Storage Garage

    Office space with quick access to Buffalo and surrounding areas.

    3764 Harlem Road, Cheektowaga, NY 14215

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    Newer Industrial/Commercial Building For Sale
    $3,500,000
    32,500 SF
    Newer Industrial/Commercial Building For Sale

    32,500 SF industrial/commercial building with office space in Lancaster, NY.

    18 Lancaster Pkwy, Lancaster, NY 14086

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    Transit Road Office/Retail Building
    $299,900
    Transit Road Office/Retail Building

    Two-story building suitable for office or retail use.

    6216 Transit Road, Depew, NY 14043

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    Renovated Building on Broadway Corner
    $299,900
    2,940 SF
    Renovated Building on Broadway Corner

    Renovated building ideal for offices or retail with parking.

    5011 Broadway, Depew, NY

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    Second Floor Office Space
    Contact for pricing
    1,500 SF
    Second Floor Office Space

    1500 SF office with 6 private offices, kitchenette.

    2335 Union Rd, Cheektowaga, NY

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    Renovated Building on Broadway Corner
    $299,900
    Renovated Building on Broadway Corner

    Renovated building suitable for offices or retail with drive-in garage.

    Cheektowaga, NY 14043

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    Versatile Retail/Office/Storage Space Available
    Contact for pricing
    Versatile Retail/Office/Storage Space Available

    4,355 SF retail/office/storage space with excellent access.

    3761 Harlem Road, Cheektowaga, NY 14215

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    Depew, NY Office Spaces Investment Opportunities Market Analysis

    Explore 72 office spaces for sale in Depew, NY, showcased through 32 active listings on our real estate platform. These investment opportunities span a total of 248,620 square feet of properties for sale, with an estimated market value of $24,395,199.

    Sale prices for office spaces in Depew, NY start at $199,000, averaging $903,525, and reaching up to $4,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 16
    Office buildings 10
    Medical Office Space 6

    Property Size Breakdown

    The majority of commercial real estate listings in Depew fall within the 100,000+ square foot range.

    Demographics Overview

    Population 25K
    Population Growth (5Y) +1.6%
    Median Household Income $73,373
    College Educated 40.0%

    High-Yield Neighborhoods for Investment

    Identify Depew submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    14043 $689.8K

    Taxes & Financing

    Tax Rate vs County Average 2.54 pp above county avg
    Average Loan-to-Value 65.0%

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    Most Searched ZIP Codes in Depew, NY

    • 14043
    • 14086
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