Advertise
    Depew, NY
    Office

    Depew, NY Office Spaces for Lease

    Notify Me
    List
    Map
    Buffalo, NY East Amherst, NY Bowmansville, NY Elma, NY Clarence, NY Queens, NY Orchard Park, NY Alden, NY
    39 properties
    Sort:
    Prime Location Retail Spaces Available
    Updated: Mar 5
    Prime Location Retail Spaces Available

    5102 Genesee Street, Depew, NY 14043

    $18 SF/Yr
    2,000 sqft
    Extremely high traffic location: Over 60,000 cars daily at the intersection of Transit Road and Genesee Street.
    Two space options available: 1,200 +/- SF turn‑key ready and 2,000 +/- SF end‑cap space ready for build‑out.
    Excellent accessibility: Located near I‑90, Kensington Expressway (Route 33), and Buffalo‑Niagara International Airport.
    Ample parking and excellent visibility.
    Located in Cheektowaga, the second‑largest suburb of Buffalo, with a population of over 88,000.
    View details
    Versatile Space in Catalyst Fitness Plaza
    Updated: Mar 5
    Versatile Space in Catalyst Fitness Plaza

    5087 Broadway, Depew, NY 14043

    $12 SF/Yr
    23,000 sqft
    High‑traffic corner location on Broadway & Penora Street with access from both streets.
    Diverse tenant mix including national retailers like Tops, Big Lots, and Dollar Tree.
    Ample parking with over 240 spaces.
    Available 23,000 +/- SF warehouse space with 2 docks and 2 drive‑in doors, divisible from 7,000 +/- SF.
    Existing 5,500 +/- SF medical office space with 23 +/- private rooms and 4 restrooms, convertible to retail.
    View details
    Medical Office Space Available
    Medical Office Space Available

    4893 Transit Road, Lancaster, NY 14043

    $25 SF/Yr
    3,004 sqft

    3,004 SF medical suite for lease on Transit Road.

    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Medical Building with Development Potential
    Medical Building with Development Potential

    3083 William St, Cheektowaga, NY 14227

    $650,000 SF/Yr
    3,200 sqft

    Partially leased medical building with developable lot on William Street.

    View details
    Class A Office Sublease
    Class A Office Sublease

    4455 Genesee St, Cheektowaga, NY 14225

    $21 SF/Yr
    8,000 sqft

    Class A office space available for sublease in Cheektowaga.

    View details
    Transit Road Office and Retail
    Transit Road Office and Retail

    4721 Transit Rd, Depew, NY 14043

    $10 SF/Yr
    1,383 sqft

    Office and retail spaces available for rent.

    View details
    Executive Office Suite
    Executive Office Suite

    5775 Broadway St, Lancaster, NY 14086

    $600/Mo

    Fresh, modern private executive offices are available with secure building access and shared conference and kitchen amenities.

    View details
    Modern Office Space Available
    Modern Office Space Available

    303 Cayuga Rd, Cheektowaga, NY

    $12 SF/Yr
    2,400 sqft

    Well-maintained office space with modern amenities and easy access.

    View details
    Medical Office & Warehouse Space
    Medical Office & Warehouse Space

    5087 Broadway, Depew, NY

    $12 SF/Yr
    5,500 sqft

    Medical office and warehouse spaces for lease in Depew.

    View details
    Office and Flex Space Available
    Office and Flex Space Available

    455 Cayuga Rd, Cheektowaga, NY

    $12 SF/Yr
    10,847 sqft

    Office and flex space for rent with private entrances.

    View details
    Temperature-Controlled Warehouse with Dock
    Temperature-Controlled Warehouse with Dock

    2540 Walden Avenue, Cheektowaga, NY 14225

    Contact for pricing
    8,000 sqft

    8,000 sq. ft. temperature-controlled warehouse includes a small office, break room, and dock door for loading and unloading.

    View details
    Two-Story Office/Retail Building
    Two-Story Office/Retail Building

    6216 Transit Road, Depew, NY 14043

    Contact for pricing
    3,044 sqft

    Two-story building with on-site front and rear parking, suited for office or retail use along Transit Road.

    View details
    Medical Office Space Available
    Medical Office Space Available

    Cheektowaga, NY

    $16 SF/Yr
    11,331 sqft

    Medical office space available for lease in 2025.

    View details
    Cheektowaga Office Suites Available
    Cheektowaga Office Suites Available

    4245 Union Rd, Cheektowaga, NY

    $12 SF/Yr
    3,400 sqft

    Executive office suites available for immediate rent in Cheektowaga.

    View details
    Lancaster Warehouse/Retail/Office Space Available
    Lancaster Warehouse/Retail/Office Space Available

    3283-3291 Walden Ave, Lancaster, NY 14043

    Contact for pricing

    Versatile space near Transit Rd with high traffic volume.

    View details
    Lancaster Retail/Office Space Available
    Lancaster Retail/Office Space Available

    3297 Walden Ave, Lancaster, NY 14043

    Contact for pricing

    3,400 SF space suitable for retail or office use.

    View details
    Industrial Space Near Walden Galleria
    Industrial Space Near Walden Galleria

    51 Anderson Rd, Cheektowaga, NY 14225

    Contact for pricing

    15,000 SF warehouse/office space available for lease.

    View details
    Former Masons' Lodge Stone Building
    Former Masons' Lodge Stone Building

    5497 Broadway, Lancaster, NY 14086

    Contact for pricing

    9,160+/- SF stone building with excellent architecture and parking.

    View details
    Prime Retail/Office Space Available
    Prime Retail/Office Space Available

    2521 Walden Avenue, Cheektowaga, NY 14225

    Contact for pricing

    Highly visible retail/office space in Cheektowaga, near airport.

    View details
    Cheektowaga Office Suites Available
    Cheektowaga Office Suites Available

    609 Dingens Street, Cheektowaga, NY 14206

    Contact for pricing
    5,800 sqft

    Office suites available in Cheektowaga's Gateway Office Park.

    View details
    Retail/Office Space Near Downtown Buffalo
    Retail/Office Space Near Downtown Buffalo

    3807 Harlem Road, Cheektowaga, NY 14215

    Contact for pricing

    Nicely finished retail/office space with quick access to Buffalo.

    View details
    Office Space with Security Service
    Office Space with Security Service

    3290 Genesee Street, Cheektowaga, NY 14225

    Contact for pricing

    Office space featuring a kitchen, conference room, and security service.

    View details
    Walden Avenue Office Space Available
    Walden Avenue Office Space Available

    1680 Walden Ave, Cheektowaga, NY 14225

    Contact for pricing
    7,000 sqft

    Office space for rent with private entrance and parking.

    View details
    Free-Standing Office Building Available
    Free-Standing Office Building Available

    1505-1517 Cleveland Dr, Cheektowaga, NY

    $12 SF/Yr
    3,780 sqft

    One-story, 3,780 SF office building with parking near airport.

    View details

    Depew, NY Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Depew, NY with 39 listings featured on our commercial real estate exchange. The current inventory includes 138,022 square feet of properties with an estimated lease value of $650,349.

    Estimated lease rates for Office Spaces in Depew, NY begin at $6.50 SF/Yr, with an average of $34,228 and extend to $650,000.
    List
    Map

    Browse Office Spaces for Lease Near Depew, NY

    Popular Searches in Depew, NY

    Popular Categories

    Most Searched ZIP Codes in Depew, NY

    • 14043
    • 14225
    • 14227
    • 14086
    • 14206
    • 14215

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!