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Williamsville, NY Office Spaces for Lease

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Amherst, NY Tonawanda, NY Cheektowaga, NY Town Of Tonawanda, NY North Tonawanda, NY Queens, NY Grand Island, NY Bowmansville, NY
250 properties
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Office Unit with Roll-Up Door
Updated: Aug 27
Office Unit with Roll-Up Door

2066 Eggert Road, Buffalo, NY 14226

$1,500/Mo
5,965 sqft 0.55 AC lot
Office unit within a multi‑unit plaza
Large roll‑up door for loading and unloading
Private bathroom and storage closets
Large picture window with vinyl and linoleum flooring
Forced‑air natural gas heating
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Medical Office Space with Exam Rooms
Updated: Jun 11
Medical Office Space with Exam Rooms

4085 Seneca Street, Buffalo, NY 14224

$2,750/Mo
1,900 sqft 0.47 AC lot
1,900‑square‑foot medical office property on 0.47 acres
Four exam rooms, waiting room, and dedicated billing office
Individual rooms may be available for lease, subject to owner approval
Ample parking and accessible approach with ramp
Forced‑air heating with natural gas and central air conditioning
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Professional Office Units with Central Air
Professional Office Units with Central Air

2555 Elmwood Avenue, Buffalo, NY 14217

$15 SF/Yr
7,344 sqft 0.28 AC lot

Flexible professional workspace includes private offices, open areas, conference capacity, and on-site parking.

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Renovated Flex Space with Warehouse
Renovated Flex Space with Warehouse

4336 Bailey Ave, Buffalo, NY 14226

$11 SF/Yr
9,635 sqft

Updated flex property combining adaptable customer-facing space with warehouse and mezzanine storage areas.

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Private Office in Shared Coworking Space
Private Office in Shared Coworking Space

625 W Ferry, Buffalo, NY 14222

$1,500/Mo per office
2,000 sqft 0.50 AC lot

Second-floor private office in a shared coworking space with utilities and internet included.

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Historic Office Suite
Historic Office Suite

1109 Delaware Avenue, Buffalo, NY 14209

$750/Mo
1,200 sqft 0.29 AC lot

Third-floor suite with three private offices, reception space, and a full bathroom.

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First-Floor Professional Office Suite
First-Floor Professional Office Suite

5900 Main Street, Buffalo, NY 14221

$2,500/Mo
1,500 sqft 0.26 AC lot

Approx. 1,500-SF office suite with a reception area, conference room, three private offices, and shared workspace.

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Renovated Retail Space
Renovated Retail Space

18 Abbott Rd, Buffalo, NY 14220

$1,800/Mo
1,220 sqft

Flexible commercial suite with private restrooms, a kitchenette, and on-site parking in South Buffalo.

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First-Floor Office Units
First-Floor Office Units

921 Main Street, Buffalo, NY 14203

$15 SF/Yr
151,938 sqft 0.79 AC lot

Divisible corner office space with zoned HVAC and access to public utilities.

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Office Units with Onsite Management
Office Units with Onsite Management

200 John James Audubon Parkway, Buffalo, NY 14228

$17 SF/Yr
82,667 sqft 5.00 AC lot

Office suites offer gross leases with janitorial service and paved on-site parking.

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West Seneca Medical/Office Space
West Seneca Medical/Office Space

220 Center Road, West Seneca, NY 14224

$4,000/Mo
4,500 sqft

4,500+/- SF medical/office space in high-traffic West Seneca location.

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Office Unit with Skylight
Office Unit with Skylight

1109 Delaware Avenue, Buffalo, NY 14209

$1,250/Mo
1,400 sqft 0.29 AC lot

Open-plan space includes a full bath, central skylight, and central air.

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Two-Story Office Building
Two-Story Office Building

3686 Seneca Street, Buffalo, NY 14224

Contact for pricing
2,603 sqft 0.53 AC lot

Configured for professional services with private offices, meeting space, reception, and on-site parking.

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First-Floor Corner Office Units
First-Floor Corner Office Units

921 Main St, Buffalo, NY 14203

$15 SF/Yr
151,938 sqft

Flexible suite configuration near a medical corridor.

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Second-Floor Office Units
Second-Floor Office Units

487 Main 2nd Floor Street, Buffalo, NY 14203

$1,950/Mo
17,360 sqft 0.06 AC lot

Three private offices, an open bullpen/conference area, kitchenette, and elevator access support varied workplace layouts.

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Office Units with Onsite Management
Office Units with Onsite Management

200 John James Audubon Pkwy, Buffalo, NY 14228

$17 SF/Yr
82,667 sqft

Gross rental terms include janitorial service, with free parking available onsite.

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Clean Office Space Near Plaza
Clean Office Space Near Plaza

3922 Seneca St, West Seneca, NY 14224

$22 SF/Yr
1,326 sqft 0.28 AC lot

Fair-conditioned office space with parking and storage included.

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Elmwood Village Shared Office Space
Elmwood Village Shared Office Space

625 West Ferry, Buffalo, NY 14222

$1,500/Mo per office
2,000 sqft

Private office in a shared workspace in Elmwood Village.

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Corner Office Building for Lease
Corner Office Building for Lease

2060 Sheridan Drive, Buffalo, NY 14223

$16 SF/Yr
12,000 sqft

Two-story office building with multiple tenant options and ample parking.

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New Office/Retail Space Available
New Office/Retail Space Available

3651 South Park Avenue, Blasdell, NY 14219

$16 SF/Yr
2,610 sqft

First-generation office/retail space for lease with customizable options.

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Broadway Corner Opportunity
Broadway Corner Opportunity

756 Broadway Street, Buffalo, NY 14212

$2,000/Mo
5,475 sqft 0.11 AC lot

Two-story building with vacant lot for lease.

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Flexible Office Suite
Flexible Office Suite

4085 Seneca Street, Buffalo, NY 14224

$2,450/Mo
1,843 sqft

Commercially zoned office space with private entry, parking, and accessible building access.

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Renovated Office Building in Williamsville
Renovated Office Building in Williamsville

395 Youngs Road, Williamsville, NY 14221

$20 SF/Yr
29,729 sqft 6.20 AC lot

Freestanding, single-story Class A office building available for lease/purchase.

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Historic Mixed-Use Building in Buffalo
Historic Mixed-Use Building in Buffalo

111 Genesee Street |, Buffalo, NY 14203

$18 SF/Yr
81,261 sqft

Restored mixed-use property with retail, office, and apartments.

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Williamsville, NY Office Spaces Lease Rates & Market Statistics

Explore 250 Office Spaces for lease in Williamsville, NY on Realmo, a commercial real estate exchange covering the Williamsville area. The current inventory totals 2,229,809 square feet of properties — an average of ~8,900 SF per listing.

Asking lease rates for Office Spaces in Williamsville start at $1.35 SF/Yr, average $14.16 SF/Yr, and reach $36 SF/Yr at the top of the market. That's a 27x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $14.16 SF/Yr, the local average runs 56% below New York's state average of $32.03 SF/Yr.

Within Erie County, most Williamsville office spaces listings are located in and around Buffalo, with additional options across the city. By space type, the market includes 175 office units, 51 office buildings and 36 medical office space listings — medical office space options typically offer the lowest entry point, while office buildings command the highest rates.

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