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South Carolina Medical Offices for Sale

127 results
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Aiken Office/Retail Space Available
$329,900
2,642 SF

Aiken Office/Retail Space Available

410 University Pkwy Unit, Aiken, SC 29801

Office or retail space in Aiken, South Carolina.

  • Flexible office space suitable for various professional uses, including non‑medical and some retail.
  • Accessible features including ramp and elevator.
  • Central air conditioning.
  • Multiple offices and large room spaces.
  • Convenient elevator access.
Updated: Jan 13
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Commercial Property Near Major Hospital
$275,000

Commercial Property Near Major Hospital

681 Chesnee Highway Ext, Spartanburg, SC 29303

Strategically located commercial property suited for medical or professional services.

  • Owner financing available.
  • Strategically located commercial property with substantial car traffic and visibility.
  • Ideally suited for a medical office or professional service near a major hospital.
  • Ample parking for employees and clients.
  • Essential amenities: kitchen, bathroom, and laundry facilities.
Updated: Sep 18, 2025
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Commercial Property Near Prisma Richland
$599,777
1,608 SF

Commercial Property Near Prisma Richland

General commercial property behind Prisma Richland Hospital with unlimited potential uses.

1901 Academy St, Columbia, SC 29203
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Eastover Office Building For Sale
$449,900
13,133 SF

Eastover Office Building For Sale

Office building in Eastover, SC with ample parking.

120 Clarkson St, Eastover, SC 29044
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Prime Commercial Property Near Hospital
$350,000
3,600 SF

Prime Commercial Property Near Hospital

Exceptional investment opportunity in downtown Sumter, across from Tuomey Hospital.

213 W Hampton Dr, Sumter, SC 29150
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Myrtle Beach Professional Office Park
$1,799,000
9,959 SF

Myrtle Beach Professional Office Park

Centrally located office park with medical/professional office space.

710 21St Ave N, Myrtle Beach, SC 29577
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Versatile Office Building Opportunity Zone
$650,000
3.31 Acres

Versatile Office Building Opportunity Zone

Office building near Prisma Hospital, suitable for medical or daycare.

512 Professional Park Park, Clinton, SC 29325
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Medical Office Near Conway Medical
Pending
$459,777
2,100 SF

Medical Office Near Conway Medical

Spacious medical office near Conway Medical Center for sale.

166 Waccamaw Medical Park Ct, Conway, SC 29526
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Medical Office Near Grand Strand
Pending
$799,888
3,888 SF

Medical Office Near Grand Strand

Spacious two-unit medical office near Grand Strand Medical Center.

917/919 Medical Cir, Myrtle Beach, SC 29572
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Wagener Four-Unit Investment Property
$239,000
5,243 SF

Wagener Four-Unit Investment Property

Fully leased four-unit property in downtown Wagener.

147-153 Main St, Wagener, SC 29164
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Greenville Office Near Medical Facilities
$950,000
0.35 Acres

Greenville Office Near Medical Facilities

Premium office space with subdivision potential near Prisma Health.

101 Chapman St, Greenville, SC 29605
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Westminster Commercial Building for Sale
$395,000
0.29 Acres

Westminster Commercial Building for Sale

Commercial building suitable for medical or business office use.

104 W Oak Hwy, Westminster, SC 29693
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Move-In Ready Office Suite
$195,000

Move-In Ready Office Suite

Professional office suite in excellent condition near hospital.

400 N Fant St, Anderson, SC 29621
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Georgetown Office Building Investment
$425,000
3,430 SF

Georgetown Office Building Investment

Commercial property suitable for medical or office use in Georgetown.

2504 Highmarket St, Georgetown, SC 29440
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Retail Opportunity in Murrells Inlet
$750,000

Retail Opportunity in Murrells Inlet

Commercial site suitable for restaurant, medical, or retail use.

4540 Highway 17 S, Murrells Inlet, SC 29576
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Turn Key Medical Office
$339,999
3,000 SF

Turn Key Medical Office

Medical office on Main Street in Mullins, South Carolina for sale.

1002 South Main St, Mullins, SC 29574
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Bluffton Commercial Space For Sale
Contact for pricing
231,304 SF

Bluffton Commercial Space For Sale

Modern retail, office, and medical space near Hampton Lake entrance.

3 Hampton Lake Dr, Bluffton, SC 29910
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Spacious Office Building in Sumter
$250,000
5,089 SF

Spacious Office Building in Sumter

Versatile 5,000+ sqft office building, ideal for various businesses.

430 N Main St, Sumter, SC 29150
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Two Professional Buildings Near MUSC
$975,000
0.82 Acres

Two Professional Buildings Near MUSC

Two professional office buildings near MUSC in Lancaster, South Carolina.

1201 Colonial Cmns Ct, Lancaster, SC 29720
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Freestanding Office Building in Rock Hill
$2,000,000
7,246 SF

Freestanding Office Building in Rock Hill

7,246 SF commercial building in high-traffic Rock Hill corridor.

1601 Ebenezer Rd, Rock Hill, SC 29732
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229 Longtown Road
$3,350,000
9,796 SF

229 Longtown Road

Medical offices • 9,796 SF

0 Longtown Rd, Columbia, SC undefined
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Charleston Office Building - $2.75M
$2,750,000
9,924 SF

Charleston Office Building - $2.75M

9,924 SF Office Building, West Ashley

14 Farmfield Ave, Charleston, SC 29407
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Spartanburg Medical Office Building
Contact for pricing
11,058 SF

Spartanburg Medical Office Building

11,058 SF medical building; strong tenant base.

480 Floyd Rd, Spartanburg, SC 29307
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101 W Market St Office Building
$150,000
1,978 SF

101 W Market St Office Building

Timmonsville Office Space - $150k

101 Market St, Timmonsville, SC 29161
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South Carolina Medical Offices Investment Opportunities Market Analysis

Explore 2589 medical offices for sale in South Carolina, showcased through 127 active listings on our real estate platform. These investment opportunities span a total of 506,044,540 square feet of properties for sale, with an estimated market value of $952,887,910.

Prices for medical spaces in South Carolina start at $50,000, averaging $974,323, and reaching up to $14,525,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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