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    Florence, SC Medical Office Space for Sale

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    Timmonsville, SC Darlington, SC Effingham, SC
    Remodeled Commercial Building Near Downtown
    $320,000
    2,165 SF
    Remodeled Commercial Building Near Downtown

    910 W Evans st, Florence, SC 29501

    Turnkey commercial property in prime location with excellent visibility.
    • Completely remodeled/rebuilt from the ground up with new roof, HVAC, electrical, and plumbing.
    • Prime location minutes from downtown Florence with excellent visibility and access.
    • Turnkey property suitable for a medical office, salon, law firm, or small business.
    • Five spacious rooms that can serve as private offices or treatment spaces.
    • Modern kitchen with brand‑new cabinets and granite countertops.
    Updated: Apr 24
    View details
    McLeod Physician Associates For Sale
    $1,384,320
    2,666 SF
    McLeod Physician Associates For Sale

    1540 American Dr, Florence, SC

    2,666 SF medical office in Florence, SC for sale.
    • Secure Investment
    • Triple Net (NNN) Lease – Landlord Has Limited Responsibilities
    • Tenant Recently Extended Lease For an Additional 5 Years, showing long‑term commitment to the site
    • Located at 1540 American Drive in Florence, SC
    • 2,666 SF McLeod Physician Associates
    Updated: Jul 24, 2025
    View details
    Medical Office Building Near MUSC
    $2,200,000
    7,950 SF
    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.

    1929 Mountain Laurel Court, Florence, SC

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 3 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 69 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Professional Office Building
    $250,000
    2,690 SF
    Versatile Professional Office Building

    Spacious office building ideal for various business uses.

    430 N Main Street, Sumter, SC 29150

    View details
    Medical/Office Building in Fairmont, NC
    $795,000
    6,889 SF
    Medical/Office Building in Fairmont, NC

    6,889 SF medical/office building for sale in Fairmont, NC.

    1212 S WALNUT Street S, Fairmont, NC 28340

    View details
    Fairmont Medical Office Building For Sale
    $795,000
    6,889 SF
    Fairmont Medical Office Building For Sale

    6,889 SF medical office building in Fairmont, North Carolina.

    1212 S Walnut Street S, Fairmont, NC 28340

    View details
    Commercial Property Near Tuomey Hospital
    $350,000
    3,600 SF
    Commercial Property Near Tuomey Hospital

    Prime commercial property with high visibility near Tuomey Hospital.

    213 W Hampton Drive, Sumter, SC 29150

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land on Highway 501
    $225,000
    1.40 Acres
    Commercial Land on Highway 501

    1.35 acre commercial land with 200 feet on Hwy 501.

    College Park Rd. lot: 1 & 2, Conway, SC 29527

    View details
    Hamlet, NC Land Opportunity
    $285,000
    10.75 Acres
    Hamlet, NC Land Opportunity

    10.75 acre tract zoned OI near Hamlet, NC.

    Wiregrass Road, Hamlet, NC 28345

    View details
    Commercial Land Near Conway Medical
    $375,000
    0.78 Acres
    Commercial Land Near Conway Medical

    Cleared commercial lot with approved medical office plans.

    Professional Park Dr. lot: 11, Conway, SC 29526

    View details
    Highway 905 Commercial Land Opportunity
    $3,500,000
    43.30 Acres
    Highway 905 Commercial Land Opportunity

    43.3 acre commercial land near Highway 22 in Conway, SC.

    Highway 905, Conway, SC 29526

    View details

    Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    316 Mcqueen St
    MEDICAL BUILDING
    1,470 SF Lot: 0.18 Acres
    Value Estimation by Request

    316 Mcqueen St, Florence, SC 29501-4723

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    1530 Mclure Ct
    MEDICAL BUILDING
    10,148 SF Lot: 1.22 Acres
    Value Estimation by Request

    1530 Mclure Ct, Florence, SC 29505-6174

    View details
    262 Cheves St
    DENTAL BUILDING
    1,460 SF Lot: 0.52 Acres
    Value Estimation by Request

    262 Cheves St, Florence, SC 29501-4404

    View details
    411 Dargan St
    MEDICAL BUILDING
    5,187 SF
    Value Estimation by Request

    411 Dargan St, Florence, SC 29506-2541

    View details
    406 Church St
    MEDICAL BUILDING
    8,160 SF Lot: 0.29 Acres
    Estimated value
    $1,445,000

    406 Church St, Florence, SC 29506-3000

    View details
    1525 Heritage Ln
    DENTAL BUILDING
    1,736 SF Lot: 0.30 Acres
    Estimated value
    $535,000

    1525 Heritage Ln, Florence, SC 29505-3141

    View details
    1260 Celebration Blvd
    MEDICAL BUILDING
    3,953 SF Lot: 0.63 Acres
    Value Estimation by Request

    1260 Celebration Blvd, Florence, SC 29501-5498

    View details
    312 Mcqueen St
    MEDICAL BUILDING
    3,225 SF Lot: 0.33 Acres
    Value Estimation by Request

    312 Mcqueen St, Florence, SC 29501-4723

    View details
    1498 Freedom Blvd
    MEDICAL BUILDING
    3,562 SF Lot: 0.92 Acres
    Estimated value
    $710,000

    1498 Freedom Blvd, Florence, SC 29505-6077

    View details
    619 Dargan St
    MEDICAL BUILDING
    3,456 SF Lot: 0.65 Acres
    Value Estimation by Request

    619 Dargan St, Florence, SC 29506-2555

    View details
    701 Dargan St
    MEDICAL BUILDING
    1,050 SF Lot: 0.19 Acres
    Value Estimation by Request

    701 Dargan St, Florence, SC 29506-2560

    View details
    1507 Heritage Ln
    DENTAL BUILDING
    4,800 SF Lot: 0.61 Acres
    Value Estimation by Request

    1507 Heritage Ln, Florence, SC 29505-3141

    View details
    517 Palmetto St
    DENTAL BUILDING
    2,797 SF Lot: 0.26 Acres
    Value Estimation by Request

    517 Palmetto St, Florence, SC 29501-4427

    View details
    2200 Irby St
    MEDICAL BUILDING
    5,996 SF Lot: 1.03 Acres
    Estimated value
    $3,190,000

    2200 Irby St, Florence, SC 29505-3423

    View details
    2410 Hoffmeyer Rd
    MEDICAL BUILDING
    4,118 SF Lot: 1.00 Acre
    Estimated value
    $2,415,000

    2410 Hoffmeyer Rd, Florence, SC 29501-7311

    View details
    1520 Freedom Blvd
    MEDICAL BUILDING
    13,196 SF Lot: 1.87 Acres
    Estimated value
    $510,000

    1520 Freedom Blvd, Florence, SC 29505-6040

    View details
    615 Palmetto St
    DENTAL BUILDING
    2,640 SF Lot: 0.39 Acres
    Value Estimation by Request

    615 Palmetto St, Florence, SC 29501-4301

    View details
    651 Coit St
    MEDICAL BUILDING
    1,678 SF Lot: 0.25 Acres
    Value Estimation by Request

    651 Coit St, Florence, SC 29501-5256

    View details
    1385 2nd Loop Rd
    DENTAL BUILDING
    3,888 SF Lot: 0.72 Acres
    Value Estimation by Request

    1385 2nd Loop Rd, Florence, SC 29505-2841

    View details
    1825 Palmetto St
    MEDICAL BUILDING
    11,322 SF Lot: 1.25 Acres
    Value Estimation by Request

    1825 Palmetto St, Florence, SC 29501-4137

    View details
    702 Coit St
    DENTAL BUILDING
    6,849 SF
    Value Estimation by Request

    702 Coit St, Florence, SC 29501-5113

    View details

    Florence, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 72 medical office space for sale in Florence, SC, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 12,781 square feet of properties for sale, with an estimated market value of $3,904,320.

    Sale prices for medical spaces in Florence, SC start at $320,000, averaging $1,301,440, and reaching up to $2,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 18
    Office buildings 10
    Medical Office Space 3

    Demographics Overview

    Population 92K
    Population Growth (5Y) -1.5%
    Median Household Income $61,793
    College Educated 17.4%

    High-Yield Neighborhoods for Investment

    Identify Florence submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    29501 $320K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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