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    Florence, SC Medical Office Space for Sale

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    Columbia, SC Aiken, SC Greenville, SC
    Remodeled Commercial Building Near Downtown
    $340,000
    2,165 SF

    Remodeled Commercial Building Near Downtown

    910 W Evans st, Florence, SC 29501

    Turnkey commercial property in prime location with excellent visibility.

    • Completely remodeled/rebuilt from the ground up with new roof, HVAC, electrical, and plumbing.
    • Prime location minutes from downtown Florence with excellent visibility and access.
    • Turnkey property suitable for a medical office, salon, law firm, or small business.
    • Five spacious rooms that can serve as private offices or treatment spaces.
    • Modern kitchen with brand‑new cabinets and granite countertops.
    Updated: Apr 1
    View details
    McLeod Physician Associates For Sale
    $1,384,320
    2,666 SF

    McLeod Physician Associates For Sale

    1540 American Dr, Florence, SC

    2,666 SF medical office in Florence, SC for sale.

    • Secure Investment
    • Triple Net (NNN) Lease – Landlord Has Limited Responsibilities
    • Tenant Recently Extended Lease For an Additional 5 Years, showing long‑term commitment to the site
    • Located at 1540 American Drive in Florence, SC
    • 2,666 SF McLeod Physician Associates
    Updated: Jul 24, 2025
    View details
    Medical Office Building Near MUSC
    $2,200,000
    7,950 SF

    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.

    1929 Mountain Laurel Court, Florence, SC
    View details
    Based on your search, we've compiled 87 Potential Opportunities for your consideration. Besides 3 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 76 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Professional Office Building
    $250,000
    2,690 SF

    Versatile Professional Office Building

    Spacious office building ideal for various business uses.

    430 N Main Street, Sumter, SC 29150
    View details
    Timmonsville Medical Office Building
    $125,000
    1,968 SF

    Timmonsville Medical Office Building

    Well-maintained 2,000 SF building suitable for various office uses.

    101 Market St, Timmonsville, SC 29161
    View details
    Timmonsville Medical Office Building
    $125,000
    1,978 SF

    Timmonsville Medical Office Building

    Well-maintained building suitable for medical or business office.

    101 W Market St, Timmonsville, SC 29161
    View details
    Commercial Property Near Tuomey Hospital
    $350,000
    3,600 SF

    Commercial Property Near Tuomey Hospital

    Prime commercial property with high visibility near Tuomey Hospital.

    213 W Hampton Drive, Sumter, SC 29150
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Highway 905 Commercial Acreage
    $3,500,000
    43.30 Acres

    Highway 905 Commercial Acreage

    43.3 acres on Highway 905, Conway, SC.

    TBD Highway 905, Conway, SC 29526
    View details
    Commercial Lot on Highway 501
    $225,000
    1.40 Acres

    Commercial Lot on Highway 501

    1.35 acre commercial lot with highway frontage in Conway.

    Lot 1 & 2 College Park Rd., Conway, SC 29527
    View details
    Commercial Lot Near Conway Medical
    $375,000
    0.78 Acres

    Commercial Lot Near Conway Medical

    Commercial lot with approved medical office plans near Conway Medical.

    Lot 11 Professional Park Dr., Conway, SC 29526
    View details
    Rockingham Land Near FirstHealth
    $50,000
    0.50 Acres

    Rockingham Land Near FirstHealth

    0.5 acre lot ideal for medical or office use.

    105 Medical Circle lot: 2, Rockingham, NC 28379
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    316 Mcqueen St

    316 Mcqueen St

    MEDICAL BUILDING • 1,470 SF
    Value Estimation by Request
    316 Mcqueen St, Florence, SC 29501-4723
    View details
    1530 Mclure Ct

    1530 Mclure Ct

    MEDICAL BUILDING • 10,148 SF
    Value Estimation by Request
    1530 Mclure Ct, Florence, SC 29505-6174
    View details
    262 Cheves St

    262 Cheves St

    DENTAL BUILDING • 1,460 SF
    Value Estimation by Request
    262 Cheves St, Florence, SC 29501-4404
    View details
    411 Dargan St

    411 Dargan St

    MEDICAL BUILDING • 5,187 SF
    Value Estimation by Request
    411 Dargan St, Florence, SC 29506-2541
    View details
    406 Church St

    406 Church St

    MEDICAL BUILDING • 8,160 SF
    Value Estimation
    $1,445,000
    406 Church St, Florence, SC 29506-3000
    View details
    1525 Heritage Ln

    1525 Heritage Ln

    DENTAL BUILDING • 1,736 SF
    Value Estimation
    $535,000
    1525 Heritage Ln, Florence, SC 29505-3141
    View details
    1260 Celebration Blvd

    1260 Celebration Blvd

    MEDICAL BUILDING • 3,953 SF
    Value Estimation by Request
    1260 Celebration Blvd, Florence, SC 29501-5498
    View details
    312 Mcqueen St

    312 Mcqueen St

    MEDICAL BUILDING • 3,225 SF
    Value Estimation by Request
    312 Mcqueen St, Florence, SC 29501-4723
    View details
    1498 Freedom Blvd

    1498 Freedom Blvd

    MEDICAL BUILDING • 3,562 SF
    Value Estimation
    $710,000
    1498 Freedom Blvd, Florence, SC 29505-6077
    View details
    619 Dargan St

    619 Dargan St

    MEDICAL BUILDING • 3,456 SF
    Value Estimation by Request
    619 Dargan St, Florence, SC 29506-2555
    View details
    701 Dargan St

    701 Dargan St

    MEDICAL BUILDING • 1,050 SF
    Value Estimation by Request
    701 Dargan St, Florence, SC 29506-2560
    View details
    1507 Heritage Ln

    1507 Heritage Ln

    DENTAL BUILDING • 4,800 SF
    Value Estimation by Request
    1507 Heritage Ln, Florence, SC 29505-3141
    View details
    517 Palmetto St

    517 Palmetto St

    DENTAL BUILDING • 2,797 SF
    Value Estimation by Request
    517 Palmetto St, Florence, SC 29501-4427
    View details
    2200 Irby St

    2200 Irby St

    MEDICAL BUILDING • 5,996 SF
    Value Estimation
    $3,190,000
    2200 Irby St, Florence, SC 29505-3423
    View details
    2410 Hoffmeyer Rd

    2410 Hoffmeyer Rd

    MEDICAL BUILDING • 4,118 SF
    Value Estimation
    $2,415,000
    2410 Hoffmeyer Rd, Florence, SC 29501-7311
    View details
    1520 Freedom Blvd

    1520 Freedom Blvd

    MEDICAL BUILDING • 13,196 SF
    Value Estimation
    $510,000
    1520 Freedom Blvd, Florence, SC 29505-6040
    View details
    615 Palmetto St

    615 Palmetto St

    DENTAL BUILDING • 2,640 SF
    Value Estimation by Request
    615 Palmetto St, Florence, SC 29501-4301
    View details
    651 Coit St

    651 Coit St

    MEDICAL BUILDING • 1,678 SF
    Value Estimation by Request
    651 Coit St, Florence, SC 29501-5256
    View details
    1385 2nd Loop Rd

    1385 2nd Loop Rd

    DENTAL BUILDING • 3,888 SF
    Value Estimation by Request
    1385 2nd Loop Rd, Florence, SC 29505-2841
    View details
    1825 Palmetto St

    1825 Palmetto St

    MEDICAL BUILDING • 11,322 SF
    Value Estimation by Request
    1825 Palmetto St, Florence, SC 29501-4137
    View details
    702 Coit St

    702 Coit St

    DENTAL BUILDING • 6,849 SF
    Value Estimation by Request
    702 Coit St, Florence, SC 29501-5113
    View details

    Florence, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 79 medical office space for sale in Florence, SC, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 3,209,108 square feet of properties for sale, with an estimated market value of $15,780,000.

    Sale prices for medical spaces in Florence, SC start at $50,000, averaging $606,923, and reaching up to $3,140,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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