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    Florence County, SC Commercial Real Estate for Sale

    220 results
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    Industrial Building in Florence, SC
    $550,000
    67,518 SF

    Industrial Building in Florence, SC

    121 Lawson St, Florence, SC 29501

    Standalone industrial building suitable for various commercial and industrial uses.

    • Standalone industrial building with approximately 5,000 SF interior space plus 2,000 SF of covered area.
    • Light Industrial zoning supports a wide range of commercial and industrial uses.
    • Suitable for fabrication, automotive uses, contractor operations, or storage.
    • Includes interior office space.
    • Features include delivery door, lifts, loading dock, security system, 220/440 volts, and drive‑in door.
    Updated: Mar 3
    View details
    Industrial Buildings with Power & Access
    $199,000
    40,000 SF

    Industrial Buildings with Power & Access

    120 N Guerry St, Florence, SC 29501

    Two industrial buildings ideal for fabrication, automotive, or storage.

    • Two standalone industrial buildings offer flexibility for various uses.
    • Light Industrial zoning supports a wide range of commercial and industrial operations.
    • Brick building features approximately 20‑foot ceilings, three‑phase power, and three roll‑up doors.
    • Concrete block building includes 5,000 SF of interior space plus 2,000 SF of covered area and interior office space.
    • Ideal for fabrication, automotive uses, contractor operations, or storage.
    Updated: Mar 1
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    Established Auto Body Business For Sale
    $1,305,000
    4,125 SF

    Established Auto Body Business For Sale

    Turn-key auto body business with equipment, client roster, and real estate.

    803 Ranch Rd, Florence, SC 29506
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    Florence Commercial Land For Sale
    $396,396
    0.91 Acres

    Florence Commercial Land For Sale

    0.91 acre commercial land parcel in Florence, South Carolina.

    Presbyterian Rd, Florence, SC 29501
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    Florence Commercial Land For Sale
    $792,792
    1.82 Acres

    Florence Commercial Land For Sale

    1.82 acre commercial land near I-95 in Florence, SC.

    Tbd Presbyterian Rd, Florence, SC 29501
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    Prime Commercial Development Site
    $980,000
    4.76 Acres

    Prime Commercial Development Site

    4.76-acre commercial land with high traffic exposure in Florence, SC.

    917 S Cashua Dr, Florence, SC 29501
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    Vacant Corner Lot For Sale
    Contact for pricing

    Vacant Corner Lot For Sale

    Vacant corner lot to be sold via online auction.

    813 Chase St, Florence, SC 29501
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    Downtown Lake City Commercial Lot
    $59,900
    0.12 Acres

    Downtown Lake City Commercial Lot

    Commercial lot in downtown Lake City, South Carolina.

    360 S Ron Mcnair Blvd, Lake City, SC 29560
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    Prime Commercial Land Near I-95
    $1,500,000
    7.27 Acres

    Prime Commercial Land Near I-95

    7.27 acres of commercial land near I-95 in Florence, SC.

    3312 Meadors Rd, Florence, SC 29501
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    Unzoned Acreage in Florence, SC
    $255,000
    6.54 Acres

    Unzoned Acreage in Florence, SC

    6.54 acres of unzoned land with potential uses.

    6.54 Acres-Tbd Alligator Rd, Florence, SC 29501
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    Olanta Commercial Building on US 301
    $75,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with restaurant and retail potential.

    405 N Jones Rd, Olanta, SC 29114
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    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Commercial Lot Near National Cemetery
    $50,000
    0.18 Acres

    Commercial Lot Near National Cemetery

    Unimproved commercial lot near Florence National Cemetery, zoned R-5A.

    Tbd National Cemetery Rd, Florence, SC 29506
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    Commercial Property on S Cashua Drive
    $638,800
    13,801 SF

    Commercial Property on S Cashua Drive

    Three buildings on three lots near Walmart in Florence, SC.

    818 Delmae Dr, Florence, SC 29501
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    Commercial Lot on Darlington Street
    $31,000
    0.19 Acres

    Commercial Lot on Darlington Street

    Vacant commercial lot with frontage on Darlington Street, Florence, SC.

    East Darlington St, Florence, SC 29506
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    Commercial Lot on Darlington Street
    $31,000
    0.19 Acres

    Commercial Lot on Darlington Street

    Commercial lot with frontage on East Darlington Street, Florence, SC.

    East Darlington St, Florence, SC 29506
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    Florence Commercial Land For Sale
    $278,784
    0.64 Acres

    Florence Commercial Land For Sale

    0.64 acre commercial land parcel in Florence, South Carolina.

    Presbyterian Rd, Florence, SC 29501
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    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 2Nd Loop Rd, Florence, SC 29501
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    Vacant Land in Florence, SC
    Contact for pricing

    Vacant Land in Florence, SC

    Vacant lot sold via online auction. Buyer responsible for due diligence.

    813 N Dargan St, Florence, SC 29506
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    Florence Commercial Land For Sale
    $49,900
    0.17 Acres

    Florence Commercial Land For Sale

    B-6 zoned property with commercial and redevelopment options.

    720 S Barringer St, Florence, SC 29506
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    Prime Land in Pamplico, SC
    $99,000
    2.00 Acres

    Prime Land in Pamplico, SC

    Two-acre commercial land with high visibility and road frontage.

    S Pamplico Hwy, Pamplico, SC 29583
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    Unrestricted Acreage in Pamplico, SC
    $250,000
    77.00 Acres

    Unrestricted Acreage in Pamplico, SC

    77+ acres of unzoned land near Florence and Myrtle Beach.

    N Old River Rd, Pamplico, SC 29583
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    Land Near Great Pee Dee
    $108,000
    15.00 Acres

    Land Near Great Pee Dee

    15-acre tract suitable for small farm or recreation.

    TRACT 5 East Myrtle Beach Hwy, Johnsonville, SC 29555
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    25 Acres Near Great Pee Dee
    $180,000
    25.00 Acres

    25 Acres Near Great Pee Dee

    25-acre tract suitable for small farm or recreational use.

    00 East Myrtle Beach Hwy, Johnsonville, SC 29555
    View details

    Florence County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 119 commercial real estate for sale in Florence County, SC, showcased through 220 active listings on our real estate platform. These investment opportunities span a total of 57,378,539 square feet of properties for sale, with an estimated market value of $62,981,041.

    Sale prices for business properties in Florence County, SC start at $31,000, averaging $723,920, and reaching up to $16,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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