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    Florence County, SC Retail Space for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    15 results
    Remodeled Commercial Building Near Downtown
    $320,000
    2,165 SF

    Remodeled Commercial Building Near Downtown

    910 W Evans st, Florence, SC 29501

    Turnkey commercial property in prime location with excellent visibility.

    • Completely remodeled/rebuilt from the ground up with new roof, HVAC, electrical, and plumbing.
    • Prime location minutes from downtown Florence with excellent visibility and access.
    • Turnkey property suitable for a medical office, salon, law firm, or small business.
    • Five spacious rooms that can serve as private offices or treatment spaces.
    • Modern kitchen with brand‑new cabinets and granite countertops.
    Updated: Apr 24
    View details
    Historic Downtown Florence Commercial Building
    $2,700,000
    16,304 SF

    Historic Downtown Florence Commercial Building

    248-260 W Evans st., Florence, SC 29501

    16,000 SF historic building in thriving downtown Florence.

    • Prime downtown Florence location in a thriving area.
    • Large 16,000 sq ft historic building with limitless potential.
    • Significant parking available (over 100 spaces), rare for downtown.
    • Versatile space currently configured with multiple tenants (Law Firm, H&R Block, Hair Studio).
    • Spacious 1.47‑acre lot allows for growth and development.
    Updated: Mar 9
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    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Downtown Lake City Commercial Building
    $199,000
    2,500 SF

    Downtown Lake City Commercial Building

    2,500 sq ft commercial building in downtown Lake City.

    112 E Main St, Lake City, SC 29560
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    Olanta Commercial Building on US 301
    $60,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114
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    Florence Commercial Development Opportunity
    $1,200,000
    4.54 Acres

    Florence Commercial Development Opportunity

    4.54 acre commercial parcel on high-traffic corridor.

    2621 West Palmetto Street, Florence, SC 29501
    View details
    Olanta Commercial Building on US 301
    $60,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114
    View details
    NNN Leased Plasma Investment Property
    $3,370,000
    17,174 SF

    NNN Leased Plasma Investment Property

    NNN leased investment property in Florence, South Carolina.

    1933 2nd Loop Rd, Florence, SC 29501
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    Evans Street Commercial Redevelopment Opportunity
    $79,000
    1,200 SF

    Evans Street Commercial Redevelopment Opportunity

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
    View details
    Historic Downtown Florence Building For Sale
    $2,800,000
    16,304 SF

    Historic Downtown Florence Building For Sale

    16,000 SF historic building in downtown Florence for sale.

    248,258, and 268 W. Evans St., Florence, SC 29501
    View details
    Versatile Office Building For Sale
    $262,500
    2,004 SF

    Versatile Office Building For Sale

    Functional office building in high traffic area, ideal for professionals.

    603 W Palmetto Street, Florence, SC 29501
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    Retail, Special Purpose
    $400,000
    3,375 SF

    Retail, Special Purpose

    Retail space · 3,375 SF

    710 S Barringer St, Florence, SC 29501
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    Corner Commercial Property For Sale
    $200,000
    1,520 SF

    Corner Commercial Property For Sale

    Commercial property with block building near downtown Florence and hospitals.

    702 S Barringer St, Florence, SC 29501
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    Retail Space on Palmetto Street
    Contact for pricing

    Retail Space on Palmetto Street

    Retail space available in a high-traffic location.

    1565 W Palmetto, Florence, SC 29501
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    Downtown Florence Commercial Property
    Contact for pricing

    Downtown Florence Commercial Property

    Commercial property in downtown Florence, suitable for office or retail.

    181 N Dargan, Florence, SC 29501
    View details
    Based on your search, we've compiled 73 Potential Opportunities for your consideration. Besides 15 Active listings in Florence County, SC, we suggest exploring several alternatives: similar 57 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime PUD-Zoned Land Opportunity
    $1,599,000
    900 SF

    Prime PUD-Zoned Land Opportunity

    2.07 acres of PUD-zoned land in a growing corridor.

    3229 State Road 207, Elkton, FL 32033
    View details

    Off-Market Properties in Florence County, SC

    Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2590 David H Mcleod Blvd
    RETAIL STORES (PERSONAL SERVICES)
    4,440 SF Lot: 0.44 Acres
    Value Estimation by Request

    2590 David H Mcleod Blvd, Florence, SC 29501-4040

    View details
    110 Dargan St
    RETAIL STORES (PERSONAL SERVICES)
    1,400 SF Lot: 0.03 Acres
    Value Estimation by Request

    110 Dargan St, Florence, SC 29506-2500

    View details
    726 Irby St
    RETAIL STORES (PERSONAL SERVICES)
    14,820 SF Lot: 0.88 Acres
    Value Estimation by Request

    726 Irby St, Florence, SC 29501-5214

    View details
    222 Broadway St
    RETAIL STORES (PERSONAL SERVICES)
    36 SF Lot: 0.40 Acres
    Value Estimation by Request

    222 Broadway St, Johnsonville, SC 29555

    View details
    1500 Irby St
    RETAIL STORES (PERSONAL SERVICES)
    14,950 SF Lot: 1.41 Acres
    Estimated value
    $1,190,000

    1500 Irby St, Florence, SC 29505-3408

    View details
    Florence, SC 29501
    RETAIL STORES (PERSONAL SERVICES)
    114,613 SF Lot: 11.74 Acres
    Estimated value
    $12,195,000

    Florence, SC 29501

    View details
    183 Main St
    RETAIL STORES (PERSONAL SERVICES)
    5,215 SF Lot: 0.14 Acres
    Value Estimation by Request

    183 Main St, Pamplico, SC 29583-9715

    View details
    114 Broadway St
    RETAIL STORES (PERSONAL SERVICES)
    2,880 SF Lot: 0.17 Acres
    Value Estimation by Request

    114 Broadway St, Johnsonville, SC 29555

    View details
    432 Price Rd, Unit A
    RETAIL STORES (PERSONAL SERVICES)
    2,880 SF Lot: 0.37 Acres
    Value Estimation by Request
    Unit A

    432 Price Rd, Florence, SC 29506-9074

    View details

    Florence County, SC Retail Space Investment Opportunities Market Analysis

    Explore 72 retail space for sale in Florence County, SC, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 66,746 square feet of properties for sale, with an estimated market value of $10,529,500.

    Sale prices for retail space in Florence County, SC start at $60,000, averaging $877,458, and reaching up to $3,370,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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