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    Florence County, SC Retail Properties & Spaces for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    35 results
    Fully Occupied Retail Center
    $1,650,000
    15,450 SF

    Fully Occupied Retail Center

    823-817 S Cashua Drive, Florence, SC 29501

    Retail center in good condition with high traffic count.

    • Fully occupied retail center, a great investment opportunity.
    • High traffic count location ensures excellent visibility.
    • Situated across the street from Walmart Neighborhood Market.
    • Two connected buildings totaling 15,450 SF (7,450 SF + 8,000 SF).
    • Buildings are in good condition.
    Updated: May 20
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    Buildable Retail Development Land
    $1,500,000
    7.27 Acres

    Buildable Retail Development Land

    3312 Meadors Road, Florence, SC 29501

    Level, buildable two-parcel land package suited for a range of retail and service-oriented development uses.

    • Two‑parcel commercial package totaling 7.27 acres
    • Located just off I‑95 with easy access
    • Directly across from a newly built Quick Trip store
    • Buildable property with utilities available nearby
    • Nearby commercial corridor with suitability for retail, service stations, and hospitality
    Updated: May 3
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    Prime Commercial Land Opportunity
    $599,000
    2.90 Acres

    Prime Commercial Land Opportunity

    2.9-acre commercial site in Lake City, SC.

    791 S Ron McNair Blvd., Lake City, SC 29560
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    Prime Commercial Site on Highway
    $599,000
    2.90 Acres

    Prime Commercial Site on Highway

    Development opportunity in high-traffic commercial corridor near industrial area.

    791 S Ron McNair Blvd, Lake City, SC 29560
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    Downtown Lake City Commercial Building
    $199,000
    2,500 SF

    Downtown Lake City Commercial Building

    2,500 sq ft commercial building in downtown Lake City.

    112 E Main St, Lake City, SC 29560
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    Olanta Commercial Building on US 301
    $60,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114
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    Florence Commercial Development Opportunity
    $1,200,000
    4.54 Acres

    Florence Commercial Development Opportunity

    4.54 acre commercial parcel on high-traffic corridor.

    2621 West Palmetto Street, Florence, SC 29501
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    Lake City Commercial Parking Lot
    $160,000
    0.47 Acres

    Lake City Commercial Parking Lot

    0.47 acre commercial lot with rental income potential.

    0.47 Acres-TBD Sumter St., Lake City, SC 29560
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    Versatile Commercial Parcel Near Downtown
    $499,900
    67,518 SF

    Versatile Commercial Parcel Near Downtown

    Office, showroom, and warehouse space less than one mile from Downtown.

    121 N Lawson St, Florence, SC 29501
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    Showroom and Warehouse on Irby
    $500,000
    6,120 SF

    Showroom and Warehouse on Irby

    Single tenant building with showroom and warehouse on 1.09-acre lot.

    511 Irby Street, Florence, SC 29501
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    Olanta Commercial Building on US 301
    $60,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114
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    Light Industrial Standalone Building
    $79,000
    1,200 SF

    Light Industrial Standalone Building

    Standalone building on a lightly industrial-zoned parcel with strong street frontage on Evans Street corridor.

    617 W Evans St, Florence, SC 29501
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    NNN Leased Plasma Investment Property
    $3,370,000
    17,174 SF

    NNN Leased Plasma Investment Property

    NNN leased investment property in Florence, South Carolina.

    1933 2nd Loop Rd, Florence, SC 29501
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    Standalone Industrial Building on Harrell
    $189,000
    40,000 SF

    Standalone Industrial Building on Harrell

    Industrial building suitable for fabrication, automotive, contractor, or storage.

    120 N Guerry St, Florence, SC 29501
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    Office/Retail Conversion Opportunity
    $400,000
    2,600 SF

    Office/Retail Conversion Opportunity

    2600 SF residence on 1.6 acres, suitable for conversion.

    2901 W Palmetto Street, Florence, SC 29501
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    Evans Street Commercial Redevelopment Opportunity
    $79,000
    1,200 SF

    Evans Street Commercial Redevelopment Opportunity

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Former Convenience Store Investment Property
    $125,000
    2,400 SF

    Former Convenience Store Investment Property

    Fixer-upper retail property with 150' frontage, great investment potential.

    1134 E Howe Springs Road, Florence, SC 29505
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    8,000 SF Retail Opportunity
    $1,521,444
    8,000 SF

    8,000 SF Retail Opportunity

    Family Dollar retail property for sale in Florence, SC.

    3216 E Palmetto St, Florence, SC 29506
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    Turnkey Fish Market Opportunity
    $250,900
    2,499 SF

    Turnkey Fish Market Opportunity

    Profitable, equipped fish market for sale in Florence, SC.

    1401 W Darlington Street, Florence, SC 29501
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    Historic Downtown Florence Building For Sale
    $2,800,000
    16,304 SF

    Historic Downtown Florence Building For Sale

    16,000 SF historic building in downtown Florence for sale.

    248,258, and 268 W. Evans St., Florence, SC 29501
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    South Irby Street Commercial Lot
    $255,000
    0.46 Acres

    South Irby Street Commercial Lot

    0.46 acre lot suitable for retail or office development.

    623 South Irby Street, Florence, SC 29501
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    Pamplico Restaurant Site For Sale
    $175,000
    2,500 SF

    Pamplico Restaurant Site For Sale

    Restaurant site for sale in Pamplico, South Carolina.

    137 East Main Street, Pamplico, SC, USA, Pamplico, SC 29583
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    Wendy's Restaurant For Sale
    Contact for pricing
    2,058 SF

    Wendy's Restaurant For Sale

    Wendy’s in Florence, South Carolina, leased for 20 years.

    4010 E Palmetto St, Florence, SC
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    Wendy’s Restaurant in Florence, SC
    Contact for pricing
    2,202 SF

    Wendy’s Restaurant in Florence, SC

    Wendy’s restaurant for sale on high-traffic retail corridor.

    624 S Irby St, Florence, SC
    View details

    Florence County, SC Retail Properties & Spaces Investment Opportunities Market Analysis

    Explore 72 retail properties & spaces for sale in Florence County, SC, showcased through 35 active listings on our real estate platform. These investment opportunities span a total of 233,958 square feet of properties for sale, with an estimated market value of $21,440,744.

    Sale prices for stores in Florence County, SC start at $60,000, averaging $824,644, and reaching up to $4,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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