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    Florence County, SC Retail Properties & Spaces for Sale

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    42 properties
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    Storefront with Original Brick
    Updated: Aug 11
    Storefront with Original Brick

    165 W Main Street, Timmonsville, SC 29161

    $150,000
    10,260 sqft 0.25 AC lot
    10,260‑square‑foot storefront property on a 0.25‑acre lot
    Prominent corner position along Main Street in downtown Timmonsville
    Upper‑level area includes newly installed windows
    Original brick architectural character remains in the building
    Built in 1920 with tile and wood flooring
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    Storefront Property with Loading Dock
    Updated: Aug 10
    Storefront Property with Loading Dock

    208 W Broadway St., Johnsonville, SC 29555

    $399,000
    9,000 sqft 1.40 AC lot
    9,000 square feet of commercial space on 1.4 acres
    Loading dock and truck doors included
    440‑Volt Power and fire alarm system
    Inside and outside storage areas
    Private restrooms with handicap access
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    Heavy Truck Repair Shop
    Heavy Truck Repair Shop

    N Cashua Dr., Florence, SC 29501

    $580,000
    1,000 sqft 2.00 AC lot

    Established mobile repair franchise serving commercial fleets and roadside service customers.

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    See what stands out in Florence County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

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    Freestanding Storefront Building
    Freestanding Storefront Building

    205 W Main St, Lake City, SC 29560

    $700,000
    5,410 sqft

    Downtown setting near businesses, banks, restaurants, and public services supports multiple commercial use options.

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    Fully Occupied Shopping Center
    Fully Occupied Shopping Center

    823-817 S Cashua Drive, Florence, SC 29501

    $1,550,000
    15,450 sqft

    Two connected retail buildings sit across from a Walmart Neighborhood Market.

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    Storefront Property with Parking
    Storefront Property with Parking

    208 W Broadway St, Johnsonville, SC 29555

    $399,000
    9,000 sqft

    Commercial building with an adaptable layout near stores and established businesses.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Storefront Building with Rear Parking
    Storefront Building with Rear Parking

    105 W Main St, Lake City, SC 29560

    $247,000
    2,425 sqft 0.50 AC lot

    Storefront building with flexible interior space, tin ceilings, and a rear lot that supports parking and future expansion.

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    Historic Mixed-Use Building in Florence
    Historic Mixed-Use Building in Florence

    248,258, and 268 W. Evans St., Florence, SC 29501

    $2,700,000
    13 sqft

    16,000 sq ft historic building in Downtown Florence for sale.

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    Flex Space with Warehouse
    Flex Space with Warehouse

    600 S Irby St., Florence, SC 29501

    Contact for pricing
    8,400 sqft 0.71 AC lot

    Office, showroom, warehouse, and storage areas support an established tire service operation.

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    Chipotle Restaurant Property
    Chipotle Restaurant Property

    2037 S. Irby Street, Florence, SC 29505

    Contact for pricing
    2,325 sqft

    Brand-new corporate-guaranteed restaurant with an absolute NNN lease and long-term renewal options.

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    Former Convenience Store Investment Property
    Former Convenience Store Investment Property

    1134 E Howe Springs Road, Florence, SC 29505

    $125,000
    2,400 sqft

    Fixer-upper retail property with 150' frontage, great investment potential.

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    Versatile Commercial Building on Acreage
    Versatile Commercial Building on Acreage

    511 Irby Street, Florence, SC 29501

    $500,000
    1.09 AC lot

    Single-tenant building with showroom, warehouse, and fenced yard.

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    Leased Multi-Tenant Retail Investment
    Leased Multi-Tenant Retail Investment

    158 South Cashua Drive, Florence, SC 29501

    Contact for pricing
    7,189 sqft

    Five-building, fully occupied multi-tenant retail property with six tenants and proven operating history.

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    Freestanding Retail Showroom and Warehouse
    Freestanding Retail Showroom and Warehouse

    2803 West Palmetto Street, Florence, SC 29501

    Contact for pricing
    15,541 sqft 0.86 AC lot

    Freestanding retail property combines showroom and warehouse space on a hard-corner site with approximately 174 feet of frontage.

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    Convenience Store with ATM and No Gas
    Convenience Store with ATM and No Gas

    120 E MAIN ST, Timmonsville, SC 29161

    Contact for pricing
    1,512 sqft

    Convenience store with ATM and no gas, built in 1930 and sized at 1,512 SF.

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    Office/Retail Conversion Opportunity
    Office/Retail Conversion Opportunity

    2901 W Palmetto Street, Florence, SC 29501

    Contact for pricing
    2,600 sqft 1.60 AC lot

    2600 SF residence on 1.6 acres, suitable for conversion.

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    Gas Station with Deli
    Gas Station with Deli

    1312 Vox Hwy, Johnsonville, SC 29555

    Contact for pricing
    2,380 sqft

    Commercially zoned gas station with a deli operation, on-site parking, and an established local customer base.

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    Family Dollar NNN Retail Property
    Family Dollar NNN Retail Property

    141 W Myrtle Beach Hwy, Johnsonville, SC 29555

    Contact for pricing
    10,500 sqft

    The lease runs through July 31, 2033, with five five-year renewal options.

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    NNN Wireless Retail Property
    NNN Wireless Retail Property

    218 N Ron McNair Blvd, Lake City, SC 29560

    Contact for pricing
    1,956 sqft

    Single-tenant wireless facility with corporate occupancy, recent renovations, and commercial zoning along a high-traffic boulevard.

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    Prime Commercial Site on Highway
    Prime Commercial Site on Highway

    791 South Ron McNair Boulevard, Lake City, SC 29560

    $599,000
    2.90 AC lot

    Development opportunity in high-traffic commercial corridor near industrial area.

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    Dollar General NNN Property
    Dollar General NNN Property

    3311 E Palmetto St, Florence, SC 29506

    Contact for pricing
    31,000 sqft

    Freestanding retail building occupied by a single corporate tenant along a commercial corridor in Florence.

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    Retail Storefront with Storage
    Retail Storefront with Storage

    114 Seaboard Ave., Johnsonville, SC 29555

    Contact for pricing
    2,150 sqft

    Retail storefront includes multiple rooms, 1.5 baths, and a separate back storage building with cement flooring.

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    South Irby Street Commercial Lot
    South Irby Street Commercial Lot

    623 South Irby Street, Florence, SC 29501

    Contact for pricing
    0.46 AC lot

    0.46 acre lot suitable for retail or office development.

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    Wendy’s Restaurant in Florence, SC
    Wendy’s Restaurant in Florence, SC

    624 S Irby St, Florence, SC

    Contact for pricing
    2,202 sqft 0.69 AC lot

    Wendy’s restaurant for sale on high-traffic retail corridor.

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    Florence County, SC Retail Properties & Spaces Market Trends and Statistics

    Explore 72 retail properties & spaces for sale in Florence County, SC, showcased through 42 active listings on our real estate platform. These investment opportunities span a total of 155,428 square feet of properties for sale, with an estimated market value of $8,128,000.

    Sale prices for stores in Florence County, SC start at $125,000, averaging $677,333, and reaching up to $2,700,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Florence County Real Estate Agencies

    Realmo connects you with licensed Florence County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Coldwell Banker McMillan and Associates
    419 S.Coit Street Florence, SC 29501
    Phone: 18436017710
    CBFlorence.com

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