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Florence County, SC Office Buildings for Sale

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20 properties
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Freestanding Storefront Building
Updated: Aug 26
Freestanding Storefront Building

205 W Main St, Lake City, SC 29560

$700,000
5,410 sqft
±5,410 SF freestanding storefront building
Retail, office, and professional service use potential
Suitable for an owner‑occupant or tenant
205 W Main Street location in downtown Lake City
Near local businesses, banks, restaurants, and public services
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205 W Main St, Lake City, SC 29560

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Historic Office Building with Parking
Updated: Mar 14
Historic Office Building with Parking

248-260 W Evans st., Florence, SC 29501

$2,700,000
16,304 sqft 1.47 AC lot
16,304 SF historic office building built in 1939
1.47‑acre site
Central air cooling; electric and heat pump heating
Law firm space: 13,759 SF with 23 offices and 7 bathrooms
8 boardrooms and meeting spaces plus reception and waiting area
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Wood-Frame Office Building
Wood-Frame Office Building

2228 W Palmetto St., Florence, SC 29501

$225,000
1,405 sqft 0.31 AC lot

Wood-frame office building with heat pump heating and central air, positioned on a commercial lot along W Palmetto St.

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Historic Downtown Office Building
Historic Downtown Office Building

260 W Evans St, Florence, SC 29501

$2,700,000
16,000 sqft 1.47 AC lot

A 16,000-square-foot historic office building with multiple suites, including a law firm and other tenants, plus over 100 parking spaces.

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Historic Downtown Florence Building For Sale
Historic Downtown Florence Building For Sale

248,258, and 268 W. Evans St., Florence, SC 29501

$2,700,000
16,304 sqft 1.47 AC lot

16,000 SF historic building in downtown Florence for sale.

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Medical Office Building with Sinks
Medical Office Building with Sinks

102 West Market Street, Timmonsville, SC 29161

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4,856 sqft 0.34 AC lot

B-4-zoned office building with separate entrances, reception areas, and adaptable medical-office infrastructure.

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Historic Downtown Office Building
Historic Downtown Office Building

248-260 W Evans st., Florence, SC 29506

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16,304 sqft 1.47 AC lot

Historic office building in downtown Florence with multiple tenant suites and over 100 parking spaces.

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Office Building with Reception Area
Office Building with Reception Area

2222 W Palmetto St, Florence, SC 29501

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1,456 sqft

Configured with private offices, a work or conference room, break room, and customer reception.

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Two-Story Office Building
Two-Story Office Building

1516 West Palmetto Street, Florence, SC 29501

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2,884 sqft

Professional office property with flexible two-level access, reception, multiple offices, and fenced rear parking.

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Freestanding Office Building For Sale
Freestanding Office Building For Sale

1221 West Evans Street, Florence, SC 29501

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1,085 sqft

Leased office building with immediate income potential in Florence.

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Freestanding Office Building with Parking
Freestanding Office Building with Parking

1500 West Evans Street, Florence, SC 29501

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2,523 sqft

Well-maintained brick office with private offices, reception, open workspace, and paved side and rear parking.

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Historic ADA-Compliant Office Building
Historic ADA-Compliant Office Building

3339 3339 Meadors Rd, Florence, SC 29501

$425,000
2,900 sqft

Commercial or residential zoning accommodates multiple occupancy options in a fully accessible building.

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Multi-Tenant Office Building
Multi-Tenant Office Building

1465 Pamplico Hwy, Florence, SC 29505

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6,768 sqft

Office building offered for sale with approximately 6,768 SF and a stated 4.92% CAP.

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Downtown Florence Business Technology Center
Downtown Florence Business Technology Center

187 E Evans St, Florence, SC

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119,567 sqft 3.29 AC lot

Office building in downtown Florence with investment and value-add potential.

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B-3 Office Building with Private Offices
B-3 Office Building with Private Offices

1205 W Evans St, Florence, SC 29501

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2,290 sqft

Configured for professional services with a lobby, private offices, open workspace, and support areas.

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Historic Downtown Florence Commercial Property
Historic Downtown Florence Commercial Property

329 N Irby St, Florence, SC 29501

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12,411 sqft 1.55 AC lot

Historic building in downtown Florence, suitable for commercial use.

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Versatile Office Building For Sale
Versatile Office Building For Sale

603 W Palmetto Street, Florence, SC 29501

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2,004 sqft

Functional office building in high traffic area, ideal for professionals.

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Downtown Office Building
Downtown Office Building

116 E Broadway St, Johnsonville, SC 29555

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The property has accommodated insurance and tax-service businesses in a downtown commercial setting.

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Office Building with Salon Buildout
Office Building with Salon Buildout

604 Second Loop Rd, Florence, SC 29505

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Office building arranged for a hair salon, with seven rooms, two bathrooms, and plenty of parking.

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Remodeled Office Building
Remodeled Office Building

183 S Coit St Unit E, Florence, SC 29501

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Five-suite professional property with reception space, private offices, storage, and private parking.

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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 20 Active Listings in Florence County, SC, we suggest to view alternatives - similar 52 Off-Market properties to explore as potential leads.

Off-Market Properties in Florence County, SC

Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

511 Evans St
OFFICE BUILDING

511 Evans St, Florence, SC 29501-3407

$160,000
Estimated value
2,145 sqft
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511 Evans St
OFFICE BUILDING

511 Evans St, Florence, SC 29501-3407

$130,000
Estimated value
1,250 sqft 0.30 AC lot
View details
908 Evans St
OFFICE BUILDING

908 Evans St, Florence, SC 29501-3442

$115,000
Estimated value
1,430 sqft 0.27 AC lot
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3036 Caterpillar Ln
OFFICE BUILDING

3036 Caterpillar Ln, Florence, SC 29506-8109

$300,000
Estimated value
672 sqft 5.65 AC lot
View details

Florence County, SC Office Buildings Market Trends and Statistics

Explore 72 office buildings for sale in Florence County, SC, showcased through 20 active listings on our real estate platform. These investment opportunities span a total of 230,471 square feet of properties for sale, with an estimated market value of $9,450,000.

Sale prices for office properties in Florence County, SC start at $225,000, averaging $1,575,000, and reaching up to $2,700,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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