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    Florence County, SC Office Buildings for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    9 results
    Historic Downtown Florence Commercial Building
    $2,700,000
    16,304 SF
    Historic Downtown Florence Commercial Building

    248-260 W Evans st., Florence, SC 29501

    16,000 SF historic building in thriving downtown Florence.
    • Prime downtown Florence location in a thriving area.
    • Large 16,000 sq ft historic building with limitless potential.
    • Significant parking available (over 100 spaces), rare for downtown.
    • Versatile space currently configured with multiple tenants (Law Firm, H&R Block, Hair Studio).
    • Spacious 1.47‑acre lot allows for growth and development.
    Updated: Mar 9
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    Florence Office Building For Sale
    $1,500,000
    7,517 SF
    Florence Office Building For Sale

    1706 Second Loop Rd., Florence, SC 29501

    7,517 SF office building on 1.34 acres in Florence.
    • Handicap access: accessible approach with ramp.
    • Features office(s) and reception area.
    • Kitchen facility available.
    • Private restrooms.
    • Central heating and central air.
    Updated: Jun 4, 2025
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    Downtown Florence Business Technology Center
    $12,000,000
    119,567 SF
    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.

    187 E Evans St, Florence, SC

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    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF
    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.

    215 John St, Lake City, SC

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    Freestanding Office Building For Sale
    $199,000
    1,085 SF
    Freestanding Office Building For Sale

    Leased office building with immediate income potential in Florence.

    1221 West Evans Street, Florence, SC 29501

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    Historic Downtown Florence Building For Sale
    $2,800,000
    16,304 SF
    Historic Downtown Florence Building For Sale

    16,000 SF historic building in downtown Florence for sale.

    248,258, and 268 W. Evans St., Florence, SC 29501

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    Historic Downtown Florence Commercial Property
    $1,100,000
    12,411 SF
    Historic Downtown Florence Commercial Property

    Historic building in downtown Florence, suitable for commercial use.

    329 N Irby St, Florence, SC 29501

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    Versatile Office Building For Sale
    $262,500
    2,004 SF
    Versatile Office Building For Sale

    Functional office building in high traffic area, ideal for professionals.

    603 W Palmetto Street, Florence, SC 29501

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    Office Building Near Downtown Florence
    Contact for pricing
    2,481 SF
    Office Building Near Downtown Florence

    Office building with private offices, conference room, and parking.

    604 S Coit, Florence, SC 29501

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 9 Active listings in Florence County, SC, we suggest exploring several alternatives: similar 63 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Development Site
    $980,000
    4.76 Acres
    Prime Commercial Development Site

    4.76-acre commercial land with high traffic exposure in Florence, SC.

    917 S Cashua Drive, Florence, SC 29501

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    Commercial Property in Kingstree, SC
    $50,000
    0.08 Acres
    Commercial Property in Kingstree, SC

    Commercial property in the heart of Kingstree, South Carolina.

    211 E Main St., Kingstree, SC 29556

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    Commercial Land on High-Traffic Highway
    $120,000
    1.21 Acres
    Commercial Land on High-Traffic Highway

    1.21 acre corner lot ideal for commercial development.

    US Highway 1 / South Seventh St, Mcbee, SC 29101

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    Commercial Land on Highway 501
    $225,000
    1.40 Acres
    Commercial Land on Highway 501

    1.35 acre commercial land with 200 feet on Hwy 501.

    College Park Rd. lot: 1 & 2, Conway, SC 29527

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    Off-Market Properties in Florence County, SC

    Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    511 Evans St
    OFFICE BUILDING
    2,145 SF
    Value Estimation by Request

    511 Evans St, Florence, SC 29501-3407

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    511 Evans St
    OFFICE BUILDING
    1,250 SF Lot: 0.30 Acres
    Value Estimation by Request

    511 Evans St, Florence, SC 29501-3407

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    908 Evans St
    OFFICE BUILDING
    1,430 SF Lot: 0.27 Acres
    Value Estimation by Request

    908 Evans St, Florence, SC 29501-3442

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    3036 Caterpillar Ln
    OFFICE BUILDING
    672 SF Lot: 5.65 Acres
    Value Estimation by Request

    3036 Caterpillar Ln, Florence, SC 29506-8109

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    221 Rodgers Ave
    OFFICE BUILDING
    2,929 SF Lot: 0.34 Acres
    Value Estimation by Request

    221 Rodgers Ave, Lake City, SC 29560-2151

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    1937 Palmetto St
    OFFICE BUILDING
    2,907 SF Lot: 0.72 Acres
    Value Estimation by Request

    1937 Palmetto St, Florence, SC 29506-3606

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    925 Main St
    OFFICE BUILDING
    2,100 SF Lot: 3.95 Acres
    Value Estimation by Request

    925 Main St, Lake City, SC 29560

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    1504 Evans St
    OFFICE BUILDING
    2,020 SF Lot: 0.42 Acres
    Value Estimation by Request

    1504 Evans St, Florence, SC 29501-3328

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    201 Graham St
    OFFICE BUILDING
    1,306 SF Lot: 0.13 Acres
    Value Estimation by Request

    201 Graham St, Florence, SC 29501-4314

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    125 Coit St
    OFFICE BUILDING
    2,448 SF Lot: 0.08 Acres
    Value Estimation by Request

    125 Coit St, Florence, SC 29501-4419

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    1513 Heritage Ln
    OFFICE BUILDING
    1,684 SF Lot: 0.26 Acres
    Value Estimation by Request

    1513 Heritage Ln, Florence, SC 29505-3141

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    401 Cheves St
    OFFICE BUILDING
    2,072 SF Lot: 0.21 Acres
    Value Estimation by Request

    401 Cheves St, Florence, SC 29501-4446

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    492 Cheves St
    OFFICE BUILDING
    3,705 SF
    Value Estimation by Request

    492 Cheves St, Florence, SC 29501-4447

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    3003 Palmetto St
    OFFICE BUILDING
    1,074 SF Lot: 4.15 Acres
    Value Estimation by Request

    3003 Palmetto St, Florence, SC 29506-3825

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    181 Dozier Blvd
    OFFICE BUILDING
    15,656 SF Lot: 1.37 Acres
    Estimated value
    $1,905,000

    181 Dozier Blvd, Florence, SC 29501-4026

    View details

    Florence County, SC Office Buildings Investment Opportunities Market Analysis

    Explore 72 office buildings for sale in Florence County, SC, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 175,829 square feet of properties for sale, with an estimated market value of $20,612,500.

    Sale prices for office properties in Florence County, SC start at $250,000, averaging $2,944,642, and reaching up to $12,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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