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Florence County, SC Office Spaces for Sale

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Historic Downtown Florence Commercial Property
Updated: Oct 4, 2024
Historic Downtown Florence Commercial Property

329 N Irby St, Florence, SC 29501

$1,100,000
12,411 sqft 1.55 AC lot
Historic property listed on the National Register of Historic Places.
Located in the heart of downtown Florence.
Situated on the corner of Irby and Darlington Streets.
Building size of approximately 12,411 square feet.
Property occupies approximately 1.55 acres.
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329 N Irby St, Florence, SC 29501

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Medical Office Building with Parking
Updated: Jul 10
Medical Office Building with Parking

1706 2nd Loop Rd., Florence, SC 29501

$1,650,000
8,291 sqft 1.34 AC lot
8,300 sq ft commercial facility on 1.34 acres with CI zoning
Former cardiology practice with 13 exam rooms plus X‑ray room
Includes reception lobby, executive and administrative offices, and board room
Extensive storage including a fully floored attic
Covered patient drop‑off, four‑bay carport, and 62 parking spaces
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Historic Downtown Office Building
Historic Downtown Office Building

248-260 W Evans st., Florence, SC 29501

$2,700,000
16,304 sqft 1.47 AC lot

Historic office building with multiple suites and ample on-site parking in downtown Florence.

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Office Property with Parking
Office Property with Parking

2228 W Palmetto St., Florence, SC 29501

$250,000
1,405 sqft 0.31 AC lot

Office space on a 0.31-acre lot with parking and strong visibility along W Palmetto St in Florence.

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Remodeled Medical Office Building
Remodeled Medical Office Building

910 W Evans st, Florence, SC 29501

$300,000
2,165 sqft 0.27 AC lot

Turnkey, fully rebuilt office suite with treatment-room style spaces, new HVAC, and updated plumbing and electrical.

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Historic Downtown Office Building
Historic Downtown Office Building

260 W Evans St, Florence, SC 29501

$2,700,000
16,000 sqft 1.47 AC lot

A 16,000-square-foot historic office building with multiple suites, including a law firm and other tenants, plus over 100 parking spaces.

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Commercial Office Property with Parking
Commercial Office Property with Parking

2228 W Palmetto St., Florence, SC 29501

$250,000
1,405 sqft

Office-focused commercial property along a high-traffic corridor, offering visibility, accessibility, and ample on-site parking.

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McLeod Physician Associates For Sale
McLeod Physician Associates For Sale

1540 American Dr, Florence, SC

$1,384,320
2,666 sqft 0.59 AC lot

2,666 SF medical office in Florence, SC for sale.

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Downtown Florence Business Technology Center
Downtown Florence Business Technology Center

187 E Evans St, Florence, SC

$12,000,000
119,567 sqft 3.29 AC lot

Office building in downtown Florence with investment and value-add potential.

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Historic Downtown Florence Building For Sale
Historic Downtown Florence Building For Sale

248,258, and 268 W. Evans St., Florence, SC 29501

$2,700,000
16,304 sqft 1.47 AC lot

16,000 SF historic building in downtown Florence for sale.

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Office/Retail Conversion Opportunity
Office/Retail Conversion Opportunity

2901 W Palmetto Street, Florence, SC 29501

$400,000
2,600 sqft 1.60 AC lot

2600 SF residence on 1.6 acres, suitable for conversion.

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Stand-Alone Office Building For Sale
Stand-Alone Office Building For Sale

215 John St, Lake City, SC

$250,000
1,722 sqft 0.29 AC lot

Stand-alone office building with immediate occupancy in Lake City, SC.

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Freestanding Office Building For Sale
Freestanding Office Building For Sale

1221 West Evans Street, Florence, SC 29501

$175,000
1,085 sqft

Leased office building with immediate income potential in Florence.

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Timmonsville Medical Office Building
Timmonsville Medical Office Building

101 Market St, Timmonsville, SC 29161

$125,000
1,968 sqft 0.20 AC lot

Well-maintained 2,000 SF building suitable for various office uses.

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South Irby Street Commercial Lot
South Irby Street Commercial Lot

623 South Irby Street, Florence, SC 29501

$255,000
0.46 AC lot

0.46 acre lot suitable for retail or office development.

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Timmonsville Medical Office Building
Timmonsville Medical Office Building

101 W Market St, Timmonsville, SC 29161

$125,000
1,978 sqft

Well-maintained building suitable for medical or business office.

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Industrial Warehouse with Development Potential
Industrial Warehouse with Development Potential

906 S Church St, Florence, SC 29506

$2,190,000
95,590 sqft 7.34 AC lot

95,590 SF industrial warehouse on 7.34 acres for sale.

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Versatile Office Building For Sale
Versatile Office Building For Sale

603 W Palmetto Street, Florence, SC 29501

$262,500
2,004 sqft

Functional office building in high traffic area, ideal for professionals.

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Olanta Commercial Building on US 301
Olanta Commercial Building on US 301

405 N Jones Road, Olanta, SC 29114

$60,000
1,500 sqft 0.36 AC lot

Commercial building in Olanta, SC, with multiple business possibilities.

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Office Building Near Downtown Florence
Office Building Near Downtown Florence

604 S Coit, Florence, SC 29501

Contact for pricing
2,481 sqft

Office building with private offices, conference room, and parking.

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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 20 Active Listings in Florence County, SC, we suggest to view alternatives - similar 52 Off-Market properties to explore as potential leads.

Off-Market Properties in Florence County, SC

Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

316 Mcqueen St
MEDICAL BUILDING

316 Mcqueen St, Florence, SC 29501-4723

Value Estimation by Request
1,470 sqft 0.18 AC lot
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511 Evans St
OFFICE BUILDING

511 Evans St, Florence, SC 29501-3407

Value Estimation by Request
2,145 sqft
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511 Evans St
OFFICE BUILDING

511 Evans St, Florence, SC 29501-3407

Value Estimation by Request
1,250 sqft 0.30 AC lot
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908 Evans St
OFFICE BUILDING

908 Evans St, Florence, SC 29501-3442

Value Estimation by Request
1,430 sqft 0.27 AC lot
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Florence County, SC Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Florence County, SC, showcased through 20 active listings on our real estate platform. These investment opportunities span a total of 304,965 square feet of properties for sale, with an estimated market value of $28,621,820.

Sale prices for office spaces in Florence County, SC start at $60,000, averaging $1,590,101, and reaching up to $12,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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