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    Florence, SC Office Buildings for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    7 results
    Historic Downtown Florence Commercial Building
    $2,700,000
    16,304 SF

    Historic Downtown Florence Commercial Building

    248-260 W Evans st., Florence, SC 29501

    16,000 SF historic building in thriving downtown Florence.

    • Prime downtown Florence location in a thriving area.
    • Large 16,000 sq ft historic building with limitless potential.
    • Significant parking available (over 100 spaces), rare for downtown.
    • Versatile space currently configured with multiple tenants (Law Firm, H&R Block, Hair Studio).
    • Spacious 1.47‑acre lot allows for growth and development.
    Updated: Mar 9
    View details
    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    1706 Second Loop Rd., Florence, SC 29501

    Office building with 7,517 square feet of space in Florence.

    • Handicap access: accessible approach with ramp.
    • Features office(s) and reception area.
    • Kitchen facility available.
    • Private restrooms.
    • Central heating and central air.
    Updated: Jun 4, 2025
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    Downtown Florence Business Technology Center
    $12,000,000
    119,567 SF

    Downtown Florence Business Technology Center

    Office building in downtown Florence with investment and value-add potential.

    187 E Evans St, Florence, SC
    View details
    Historic Downtown Florence Building For Sale
    $2,800,000
    16,304 SF

    Historic Downtown Florence Building For Sale

    16,000 SF historic building in downtown Florence for sale.

    248,258, and 268 W. Evans St., Florence, SC 29501
    View details
    Versatile Office Building For Sale
    $262,500
    2,004 SF

    Versatile Office Building For Sale

    Functional office building in high traffic area, ideal for professionals.

    603 W Palmetto Street, Florence, SC 29501
    View details
    Historic Downtown Florence Commercial Property
    $1,100,000
    12,411 SF

    Historic Downtown Florence Commercial Property

    Historic building in downtown Florence, suitable for commercial use.

    329 N Irby St, Florence, SC 29501
    View details
    Office Building Near Downtown Florence
    Contact for pricing
    2,481 SF

    Office Building Near Downtown Florence

    Office building with private offices, conference room, and parking.

    604 S Coit, Florence, SC 29501
    View details
    Based on your search, we've compiled 375 Potential Opportunities for your consideration. Besides 7 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 360 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Cheraw Office Building For Sale
    $160,000
    1,200 SF

    Cheraw Office Building For Sale

    Brick office building near Cheraw's Historic District.

    211 Kershaw Street, Cheraw, SC 29520
    View details
    Hartsville Office Building For Sale
    $1,100,000
    5,000 SF

    Hartsville Office Building For Sale

    5,000 sq ft office building in the heart of Hartsville.

    146 Cargill Way, Hartsville, SC 29550
    View details
    Downtown Hartsville Stand-Alone Office Building
    Contact for pricing
    2,320 SF

    Downtown Hartsville Stand-Alone Office Building

    7400 sq ft office building in downtown Hartsville.

    311 W 311.0 Home Ave, Hartsville, SC 29550
    View details
    Office Building with Prime Location
    $149,000

    Office Building with Prime Location

    Office building with five offices and two partial bathrooms.

    411 Market St, Cheraw, SC 29520
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 Second Loop Rd., Florence, SC 29501
    View details
    Prime Commercial Development Site
    $980,000
    4.76 Acres

    Prime Commercial Development Site

    4.76-acre commercial land with high traffic exposure in Florence, SC.

    917 S Cashua Drive, Florence, SC 29501
    View details
    Commercial Land on High-Traffic Highway
    $120,000
    1.21 Acres

    Commercial Land on High-Traffic Highway

    1.21 acre corner lot ideal for commercial development.

    US Highway 1 / South Seventh St, Mcbee, SC 29101
    View details
    Commercial Lot in Kingstree, SC
    $50,000
    0.08 Acres

    Commercial Lot in Kingstree, SC

    Commercial property in the heart of Kingstree, South Carolina.

    211 E Main St., Kingstree, SC 29556
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    511 Evans St

    511 Evans St

    OFFICE BUILDING • 2,145 SF
    Value Estimation by Request
    511 Evans St, Florence, SC 29501-3407
    View details
    511 Evans St

    511 Evans St

    OFFICE BUILDING • 1,250 SF
    Value Estimation by Request
    511 Evans St, Florence, SC 29501-3407
    View details
    908 Evans St

    908 Evans St

    OFFICE BUILDING • 1,430 SF
    Value Estimation by Request
    908 Evans St, Florence, SC 29501-3442
    View details
    3036 Caterpillar Ln

    3036 Caterpillar Ln

    OFFICE BUILDING • 672 SF
    Value Estimation by Request
    3036 Caterpillar Ln, Florence, SC 29506-8109
    View details
    1937 Palmetto St

    1937 Palmetto St

    OFFICE BUILDING • 2,907 SF
    Value Estimation by Request
    1937 Palmetto St, Florence, SC 29506-3606
    View details
    1504 Evans St

    1504 Evans St

    OFFICE BUILDING • 2,020 SF
    Value Estimation by Request
    1504 Evans St, Florence, SC 29501-3328
    View details
    201 Graham St

    201 Graham St

    OFFICE BUILDING • 1,306 SF
    Value Estimation by Request
    201 Graham St, Florence, SC 29501-4314
    View details
    125 Coit St

    125 Coit St

    OFFICE BUILDING • 2,448 SF
    Value Estimation by Request
    125 Coit St, Florence, SC 29501-4419
    View details
    1513 Heritage Ln

    1513 Heritage Ln

    OFFICE BUILDING • 1,684 SF
    Value Estimation by Request
    1513 Heritage Ln, Florence, SC 29505-3141
    View details
    401 Cheves St

    401 Cheves St

    OFFICE BUILDING • 2,072 SF
    Value Estimation by Request
    401 Cheves St, Florence, SC 29501-4446
    View details
    492 Cheves St

    492 Cheves St

    OFFICE BUILDING • 3,705 SF
    Value Estimation by Request
    492 Cheves St, Florence, SC 29501-4447
    View details
    3003 Palmetto St

    3003 Palmetto St

    OFFICE BUILDING • 1,074 SF
    Value Estimation by Request
    3003 Palmetto St, Florence, SC 29506-3825
    View details
    181 Dozier Blvd

    181 Dozier Blvd

    OFFICE BUILDING • 15,656 SF
    Value Estimation
    $1,905,000
    181 Dozier Blvd, Florence, SC 29501-4026
    View details
    1323 Celebration Blvd

    1323 Celebration Blvd

    OFFICE BUILDING • 99,628 SF
    Value Estimation
    $8,810,000
    1323 Celebration Blvd, Florence, SC 29501-5496
    View details
    1608 Palmetto St

    1608 Palmetto St

    OFFICE BUILDING • 1,674 SF
    Value Estimation by Request
    1608 Palmetto St, Florence, SC 29501-4134
    View details
    603 Palmetto St

    603 Palmetto St

    OFFICE BUILDING • 2,004 SF
    Value Estimation by Request
    603 Palmetto St, Florence, SC 29501-4301
    View details
    236 Evans St

    236 Evans St

    OFFICE BUILDING • 1,998 SF
    Value Estimation by Request
    236 Evans St, Florence, SC 29501-3428
    View details

    Florence, SC Office Buildings Investment Opportunities Market Analysis

    Explore 367 office buildings for sale in Florence, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 11,212,776 square feet of properties for sale, with an estimated market value of $112,605,000.

    Sale prices for office properties in Florence, SC start at $50,000, averaging $674,281, and reaching up to $15,640,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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