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    Florence County, SC Commercial Real Estate for Sale

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    Recreation Land with Warehouse
    Recreation Land with Warehouse

    1315 Hill Harrell Road, Effingham, SC 29541

    $1,149,000
    158.59 AC lot

    Expansive recreational tract with cleared ground, a stocked pond, utility service, and substantial covered improvements.

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    Corner Commercial Land
    Corner Commercial Land

    360 S Ron McNair Blvd, Lake City, SC 29560

    $59,900
    1,200 sqft 0.12 AC lot

    Corner commercial parcel with brick construction, concrete flooring, and central air.

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    Commercial Land Parcel
    Commercial Land Parcel

    1714 2nd Loop Rd., Florence, SC 29501

    $1,650,000
    4.03 AC lot

    Vacant tract with FV zoning and convenient access from 2nd Loop Road.

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    See what stands out in Florence County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

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    Medical Office Building with Sinks
    Medical Office Building with Sinks

    102 West Market Street, Timmonsville, SC 29161

    Contact for pricing
    4,856 sqft 0.34 AC lot

    B-4-zoned office building with separate entrances, reception areas, and adaptable medical-office infrastructure.

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    B-6 Zoned Commercial Land
    B-6 Zoned Commercial Land

    720 S Barringer Street, Florence, SC 29506

    $47,900
    840 sqft 0.17 AC lot

    Commercial parcel near two Florence medical centers, offered in its existing condition for redevelopment or other commercial plans.

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    Corner Commercial Land
    Corner Commercial Land

    635 N Coit St., Florence, SC 29501

    $265,000
    0.91 AC lot

    Flat, buildable commercial site with utilities available at a prominent corner location.

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    Unzoned Development Acreage with Utilities
    Unzoned Development Acreage with Utilities

    1829 S Pamplico Hwy., Pamplico, SC 29583

    $168,900
    9.06 AC lot

    About 9 acres of mostly cleared unzoned land with water and electric hookups plus a poured house pad.

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    Flex Space with Warehouse
    Flex Space with Warehouse

    600 S Irby St., Florence, SC 29501

    Contact for pricing
    8,400 sqft 0.71 AC lot

    Office, showroom, warehouse, and storage areas support an established tire service operation.

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    Commercial Land Development Site
    Commercial Land Development Site

    3312 Meadors Road, Florence, SC 29501

    $1,500,000
    7.27 AC lot

    Level, buildable acreage near I-95 with utilities available nearby.

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    Signalized-Intersection Commercial Land
    Signalized-Intersection Commercial Land

    2365 Pamplico Hwy., Florence, SC 29505

    $525,000
    0.89 AC lot

    Unzoned commercial parcel with highway access near Florence’s medical district and retail corridor.

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    Chipotle Restaurant Property
    Chipotle Restaurant Property

    2037 S. Irby Street, Florence, SC 29505

    Contact for pricing
    2,325 sqft

    Brand-new corporate-guaranteed restaurant with an absolute NNN lease and long-term renewal options.

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    Commercial Land Parcel
    Commercial Land Parcel

    W Leggs Cir, Florence, SC 29501

    $129,900
    4.00 AC lot

    Four-acre commercial land parcel with CA zoning in Florence County.

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    Commercial Redevelopment Land Parcel
    Commercial Redevelopment Land Parcel

    2931 Republic Avenue, Florence, SC 29501

    $75,000
    0.97 AC lot

    Nearly one-acre commercial-zoned lot in Florence, SC, sold as-is with an abandoned structure on-site.

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    Office-Warehouse Flex Facility
    Office-Warehouse Flex Facility

    1829 Habersham Square, Florence, SC 29501

    Contact for pricing
    5,000 sqft 0.81 AC lot

    Office space with three private offices and a reception area complements a warehouse with two drive-in doors.

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    Agricultural Land with Home
    Agricultural Land with Home

    711 Cade Rd., Lake City, SC 29560

    $430,000
    66.00 AC lot

    66+/- acre property includes cropland, wetlands, and a 1,376-square-foot home with three bedrooms and one bathroom.

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    Corner Commercial Land
    Corner Commercial Land

    360 N Dargan St, Florence, SC 29501

    $75,000
    0.10 AC lot

    Commercially zoned corner parcel with a compact footprint in an established street setting.

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    Former Convenience Store Investment Property
    Former Convenience Store Investment Property

    1134 E Howe Springs Road, Florence, SC 29505

    $125,000
    2,400 sqft

    Fixer-upper retail property with 150' frontage, great investment potential.

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    Cleared Upland Land
    Cleared Upland Land

    N Old Georgetown Rd., Scranton, SC 29591

    $64,000
    7.35 AC lot

    The property includes cleared uplands, no zoning restrictions, and a completed perc test.

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    Historic ADA-Compliant Office Building
    Historic ADA-Compliant Office Building

    3339 3339 Meadors Rd, Florence, SC 29501

    $425,000
    2,900 sqft

    Commercial or residential zoning accommodates multiple occupancy options in a fully accessible building.

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    Agricultural Land with Open Fields
    Agricultural Land with Open Fields

    81.30 Acres - Blackberry Rd., Johnsonville, SC 29555

    $650,400
    81.30 AC lot

    Ag-zoned farmland combines open fields with mature hardwood and pine cover.

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    Commercial Office Property with Parking
    Commercial Office Property with Parking

    2228 W Palmetto St., Florence, SC 29501

    Contact for pricing
    1,405 sqft

    Office-focused commercial property along a high-traffic corridor, offering visibility, accessibility, and ample on-site parking.

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    Cleared Commercial Land
    Cleared Commercial Land

    S Georgetown Hwy., Johnsonville, SC 29555

    $160,000
    0.67 AC lot

    Cleared commercial lot with Res zoning and highway access in Johnsonville.

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    Historic Downtown Office Building
    Historic Downtown Office Building

    248-260 W Evans st., Florence, SC 29506

    Contact for pricing
    16,304 sqft 1.47 AC lot

    Historic office building in downtown Florence with multiple tenant suites and over 100 parking spaces.

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    Hunting Land with Open Fields
    Hunting Land with Open Fields

    85+/- Acres - Antler Dr, Johnsonville, SC 29555

    $680,000
    85.00 AC lot

    Mixed open fields, hardwood swamp, and timber create habitat for waterfowl, deer, and turkey.

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