Orangeburg County, SC Commercial Real Estate for Sale

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107 properties
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Flex Space with Showroom
Updated: Oct 15
Flex Space with Showroom

1885 Joe S Jeffords Highway, Orangeburg, SC 29115

$575,000
9,600 sqft 2.40 AC lot
9,600 SF building with showroom, offices and warehouse areas
Warehouse fitted with a 3 ton crane
2.4‑acre site at a lighted intersection where three highways converge
Approximately 30,000 vehicles pass daily
New roof and updated office flooring
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Office Building with Outbuilding
Updated: Sep 24
Office Building with Outbuilding

771 Dantzler Street, Orangeburg, SC 29115

$225,000
2,492 sqft 0.45 AC lot
2,492 square feet across two separate buildings
0.45‑acre lot with multiple fenced outdoor areas
Main building includes five private offices and a reception area
Full kitchen, four bathrooms, and laundry hookups
Secondary building provides two rooms and one bathroom
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Flex Space with Warehouse
Flex Space with Warehouse

2874 Bamberg Road, Orangeburg, SC 29115

$249,900
6,000 sqft 0.59 AC lot

Two-building commercial property combines climate-controlled office and retail space with a dedicated warehouse building.

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Medical Office Building with Excess Land
Medical Office Building with Excess Land

8532 Old State Rd, Holly Hill, SC 29059

$1,400,000
6,280 sqft

Medical office property with adjacent excess land for future expansion, parking, or owner-user planning.

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Restaurant Building with Kitchen Equipment
Restaurant Building with Kitchen Equipment

8291 Savannah Highway, Norway, SC 29113

$279,000
2,800 sqft 0.59 AC lot

Commercial restaurant property with established food-service infrastructure, customer parking, and direct access from Savannah Highway.

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Commercial Land with Highway Frontage
Commercial Land with Highway Frontage

4 Old Number Six Highway, Vance, SC 29163

$229,990
2.78 AC lot

Partially cleared land with two curb cuts and direct access from Old Number Six Highway.

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Self-Storage Facility with Business Space
Self-Storage Facility with Business Space

9158 Old Number Six Highway, Santee, SC 29142

$1,900,000
3,282 sqft 1.00 AC lot

Commercial property combines rentable storage units with flexible space for two separate businesses and additional office or storage use.

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Two-Building Office Property
Two-Building Office Property

771 Dantzler St, Orangeburg, SC 29115

$250,000
2,492 sqft 0.45 AC lot

Five private offices, a reception area, and a full kitchen support a range of professional operations.

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Single-Level Live-Work Property
Single-Level Live-Work Property

109 Haddock Road NW, Orangeburg, SC 29115

$190,000
0.16 AC lot

CG zoning permits residential occupancy and specified commercial uses, subject to applicable local requirements.

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Church Facility With Multipurpose Hall
Church Facility With Multipurpose Hall

200 Stephens Street, Branchville, SC 29432

$224,900
0.52 AC lot

Commercial zoning, public water, and three restrooms support a flexible existing facility.

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Two-Building Office Property
Two-Building Office Property

771 Dantzler Street, Orangeburg, SC 29115

$225,000
2,492 sqft 0.45 AC lot

Five private offices, reception space, and a separate two-room structure support a range of professional layouts.

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Interstate-Frontage Industrial Land
Interstate-Frontage Industrial Land

3246 Belleville Road, Orangeburg, SC 29115

$29,900,000
161.10 AC lot

Large industrial tract at a major interstate and local-road intersection with public utilities available nearby.

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Commercial Land with Frontage
Commercial Land with Frontage

Magnolia Street, Orangeburg, SC 29118

$195,000
3.49 AC lot

General Commercial land with utility access and substantial street exposure for commercial development.

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Turnkey Equestrian Property with Log Home
Turnkey Equestrian Property with Log Home

1084 Farnum Road, Orangeburg, SC 29118

$1,125,000
3,493 sqft

Established horse facility with extensive acreage, two barns, private trails, and a well-appointed three-bedroom residence.

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Neighborhood Commercial Mixed-Use Property
Neighborhood Commercial Mixed-Use Property

2918 Cleveland Street, Elloree, SC 29047

$69,900
0.68 AC lot

Two-building commercial property with public water, public sewer, and dedicated parking area.

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Corner Commercial Land
Corner Commercial Land

Magnolia Street, Orangeburg, SC 29118

$125,000
1.67 AC lot

General Commercial-zoned corner parcel with public water, natural gas, and overhead electric access.

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Restaurant-Ready Retail Building
Restaurant-Ready Retail Building

8291 Savannah Hwy, Norway, SC 29113

$279,000
2,800 sqft

Built in 2016, the building is already equipped for restaurant operations and includes multiple walk-in and cooking prep features.

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Branchville, SC 15.54-Acre Tract
Branchville, SC 15.54-Acre Tract

1 Lost Horn Road, Branchville, SC 29432

$100,000
15.54 AC lot

15.54-acre wooded property in Branchville, SC for sale.

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Irrigated Farmland with Center Pivot
Irrigated Farmland with Center Pivot

1 Disadore Drive, Neeses, SC 29107

$1,080,000
4,704,480 sqft 108.00 AC lot

108+/- acres of irrigated sod farm with center pivot irrigation systems supporting active crop production.

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Irrigated Sod Farm
Irrigated Sod Farm

1 Disadore Drive, Neeses, SC 29107

$1,080,000
108.00 AC lot

Operating sod farm with center pivot irrigation across a substantial agricultural tract.

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Freestanding Storefront Property
Freestanding Storefront Property

6711 Charleston Highway, Bowman, SC 29018

Contact for pricing
8,011 sqft

An 8,011-square-foot storefront positioned along Charleston Highway in Bowman, South Carolina.

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Private Agricultural Land
Private Agricultural Land

3120 Savannah Highway, North, SC 29112

$297,000
22.00 AC lot

Rural acreage with planted screening, a cleared homesite area, and public water availability.

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Mixed-Use Park Near Medical Center
Mixed-Use Park Near Medical Center

1717-1719 Village Park Drive, Orangeburg, SC 29118

Contact for pricing
4,650 sqft

Nineteen-building commercial campus supports medical, professional office, and retail uses.

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Commercial Land with Road Frontage
Commercial Land with Road Frontage

Whittaker Parkway, Orangeburg, SC 29115

$299,000
12.46 AC lot

Commercial tract with public water and multiple access points for future development.

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Orangeburg County, SC Commercial Real Estate Market Trends and Statistics

Explore 107 commercial real estate for sale in Orangeburg County, SC, showcased through 107 active listings on our real estate platform. These investment opportunities span a total of 14,006,126 square feet of properties for sale, with an estimated market value of $112,794,355.

Sale prices for business properties in Orangeburg County, SC start at $33,900, averaging $1,762,411, and reaching up to $29,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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