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    Florence County, SC Retail Properties & Spaces for Lease

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    19 properties
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    Flexible Office Unit
    Updated: Jul 26
    Flexible Office Unit

    1604 2nd Loop Rd, Florence, SC 29501

    $2,000/Mo
    1,000 sqft
    Approximately 1,000 square feet of commercial space
    Flexible floor plan for office, medical, retail, or service‑oriented uses
    High‑visibility setting with exposure to local and through traffic
    Convenient access and ample parking
    Located at 1604 2nd Loop Rd, Florence, SC 29501
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    Retail Spaces in CrossRoads Center
    Updated: Apr 2
    Retail Spaces in CrossRoads Center

    2522, 2524, 2528 David H McLeod Blvd, Florence, SC 29501

    $18,134/Mo
    95,840 sqft
    High‑traffic location in Florence's main commercial corridor.
    Convenient access to Interstate 20 and Interstate 95.
    Located adjacent to Magnolia Mall.
    Available spaces of ±18,134, ±34,430, and ±43,276 square feet.
    Strong visibility to attract local residents and visitors.
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    Shopping Center Retail Space
    Shopping Center Retail Space

    1945 W Palmetto St, Florence, SC 29501

    Contact for pricing
    4,062 sqft

    Retail space within a multi-tenant center, available for occupancy in 60 days.

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    Visible Retail Showroom Suite
    Visible Retail Showroom Suite

    1725 West Palmetto Street, Florence, SC 29501

    Contact for pricing
    1,140 sqft

    Open retail space with storage, restroom, shared parking, and exposure along W. Palmetto Street.

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    High-Traffic Retail Shopping Center
    High-Traffic Retail Shopping Center

    2522-2530 David H McLeod Blvd, Florence, SC 29501

    Contact for pricing
    43,276 sqft

    Retail space within a high-traffic corridor just off I-20 and I-95 in Florence, SC.

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    Retail Space in Shopping Center
    Retail Space in Shopping Center

    2522-2530 David H McLeod Blvd, Florence, SC 29501

    Contact for pricing
    34,430 sqft

    Retail space located in a high-traffic retail hub along David H McLeod Blvd, just off I-20 and I-95.

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    Multi-Tenant Retail Office Building
    Multi-Tenant Retail Office Building

    181 S Cashua Dr, Florence, SC 29501

    Contact for pricing
    7,500 sqft 1.83 AC lot

    Shell space with a rear drive-in door, front parking, and monument and above-suite signage options along S Cashua Drive.

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    Retail Storefront in Redevelopment Hub
    Retail Storefront in Redevelopment Hub

    2295 Hoffmeyer Rd, Florence, SC 29501

    Contact for pricing
    3,441 sqft

    Retail storefront on Hoffmeyer Rd within an emerging mixed-use retail and lifestyle redevelopment.

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    Mixed-Use Retail and Office Space
    Mixed-Use Retail and Office Space

    2295 Hoffmeyer Rd, Florence, SC 29501

    Contact for pricing
    7,465 sqft

    7,465-square-foot property within a redevelopment featuring retail, office, medical, dining, and lifestyle spaces.

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    Retail Space with High-Traffic Frontage
    Retail Space with High-Traffic Frontage

    2295 Hoffmeyer Rd, Florence, SC 29501

    Contact for pricing
    8,750 sqft

    Retail space in West End District with 18,300+ AADT on Hoffmeyer Rd and combined traffic counts exceeding 30,000 VPD.

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    Retail Space
    Retail Space

    2201 Hoffmeyer Road, Florence, SC 29501

    Contact for pricing

    Multiple retail configurations are available for lease in Florence.

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    Remodeled Retail Space with Signage
    Remodeled Retail Space with Signage

    2221 Pamplico Highway, Florence, SC 29505

    Contact for pricing

    Two remodeled buildings offer retail and office configurations with on-site parking.

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    Warehouse with Showroom and Yard
    Warehouse with Showroom and Yard

    511 Irby Street, Florence, SC 29501

    Contact for pricing
    1.09 AC lot

    Single tenant building with showroom, warehouse, and fenced yard.

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    Retail Space in Mixed-Use District
    Retail Space in Mixed-Use District

    2295 Hoffmeyer Rd, Florence, SC 29501

    Contact for pricing

    Retail space is part of a mixed-use redevelopment anchored near Hoffmeyer Road traffic corridors.

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    Retail Space in Florence, SC
    Retail Space in Florence, SC

    2600 David H Mcleod Blvd, Florence, SC

    Contact for pricing
    8,000 sqft 4.31 AC lot

    8,000 SF retail space available for lease.

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    Renovated Retail Space on US-52
    Renovated Retail Space on US-52

    1611 S Irby St, Florence, SC 29505

    Contact for pricing
    22,800 sqft 13.70 AC lot

    Anchor suite in renovated shopping center with high visibility.

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    Retail Space at Claussen Shops
    Retail Space at Claussen Shops

    2332 Pamplico Hwy, Florence, SC 29505

    Contact for pricing
    3,600 sqft

    Grocery-anchored retail space for lease with ample parking.

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    Established Commercial Complex on Second Loop
    Established Commercial Complex on Second Loop

    1800 2nd Loop Rd, Florence, SC 29501

    Contact for pricing
    2,000 sqft

    Multi-tenant commercial complex with high visibility and convenient access.

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    Retail Space in Florence Mall
    Retail Space in Florence Mall

    1945 W Palmetto St, Florence, SC 29501

    Contact for pricing
    329,000 sqft

    Prime retail space in regional shopping center, Florence, South Carolina.

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    Based on your search, we've compiled 61 Potential Opportunities for your consideration. Besides 19 Active listings in Florence County, SC, we suggest exploring alternatives. Similar 42 Properties for Sales.

    Similar Spaces for Sale in Florence County, SC

    Consider Similar Space for Sale. We found 42 Spaces matching your search parameters.

    Freestanding Storefront Building
    Freestanding Storefront Building

    205 W Main St, Lake City, SC 29560

    $700,000
    5,410 sqft

    Downtown setting near businesses, banks, restaurants, and public services supports multiple commercial use options.

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    Storefront with Original Brick
    Storefront with Original Brick

    165 W Main Street, Timmonsville, SC 29161

    $150,000
    10,260 sqft 0.25 AC lot

    Large commercial space with natural-light improvements and substantial renovation needs.

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    Storefront Property with Loading Dock
    Storefront Property with Loading Dock

    208 W Broadway St., Johnsonville, SC 29555

    $399,000
    9,000 sqft 1.40 AC lot

    Commercial space with loading access, private restrooms, storage, and 440-Volt Power.

    View details
    Heavy Truck Repair Shop
    Heavy Truck Repair Shop

    N Cashua Dr., Florence, SC 29501

    $580,000
    1,000 sqft 2.00 AC lot

    Established mobile repair franchise serving commercial fleets and roadside service customers.

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    Fully Occupied Shopping Center
    Fully Occupied Shopping Center

    823-817 S Cashua Drive, Florence, SC 29501

    $1,550,000
    15,450 sqft

    Two connected retail buildings sit across from a Walmart Neighborhood Market.

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    Florence County, SC Retail properties & Spaces Market Trends and Statistics

    Explore Retail properties & Spaces leasing options in Florence County, SC with 19 listings featured on our commercial real estate exchange. The current inventory includes 572,304 square feet of properties with an estimated lease value of $26.27.

    Estimated lease rates for Retail properties & Spaces in Florence County, SC begin at $2.27 SF/Yr, with an average of $13.13 SF/Yr and extend to $24 SF/Yr.
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    Featured Florence County Real Estate Agencies

    Realmo connects you with licensed Florence County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Coldwell Banker McMillan and Associates
    419 S.Coit Street Florence, SC 29501
    Phone: 18436017710
    CBFlorence.com

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