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Florence County, SC Land for Sale

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163 results
Prime Commercial Development Site
$980,000
4.76 Acres

Prime Commercial Development Site

917 S Cashua Drive, Florence, SC 29501

4.76-acre commercial land with high traffic exposure in Florence, SC.

  • High traffic volume: Approximately 30,700 vehicles per day (AADT).
  • Prime commercial development site on a four‑lane corridor.
  • B3 zoning suitable for various commercial uses (retail, QSR, medical, etc.).
  • Located near major retail and daily‑use anchors (Walmart Neighborhood Market, gas station, grocery, restaurants).
  • Development‑ready: High and level site.
Updated: Jan 27
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Prime Commercial Lot on Highway
$599,000
2.90 Acres

Prime Commercial Lot on Highway

791 S Ron McNair Blvd., Lake City, SC 29560

2.9-acre commercial site on S. Ron McNair Boulevard, Lake City.

  • ±2.90‑acre commercial site on S. Ron McNair Boulevard / Highway 52 corridor.
  • High traffic count of approximately 15,000 vehicles per day.
  • Located adjacent to Nan Ya Plastics, a major regional employer.
  • Clean Phase I Environmental Site Assessment in hand.
  • Site will be cleared of existing structures for redevelopment.
Updated: Mar 9
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Prime Commercial Land Near I-95
$1,500,000
7.27 Acres

Prime Commercial Land Near I-95

7.27 acres of commercial land near I-95 in Florence, SC.

3312 Meadors Road, Florence, SC 29501
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78.4 Acres with Cropland
$515,000
78.40 Acres

78.4 Acres with Cropland

78.4-acre property featuring cropland, wetlands, and a 1,376-square-foot home.

711 Cade Rd., Lake City, SC 29560
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Prime Location Commercial Land
$265,000
2,422 SF

Prime Location Commercial Land

Commercial land in a prime location, sold as is.

818 S Cashua Drive, Florence, SC 29501
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Downtown Lake City Commercial Lot
$59,900
1,200 SF

Downtown Lake City Commercial Lot

Commercial lot in downtown Lake City, South Carolina.

360 S Ron McNair Blvd, Lake City, SC 29560
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Expansive Land in Pamplico, SC
$179,900
9.06 Acres

Expansive Land in Pamplico, SC

9-acre property near North Myrtle Beach and Florence.

9.06 Acres-1829 S Pamplico Hwy., Pamplico, SC 29583
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200 Acres Recreational Land Peninsula
$880,000
200.00 Acres

200 Acres Recreational Land Peninsula

200-acre peninsula with riverfront, recreational opportunities, and abundant wildlife.

0 Allison Landing Road, Johnsonville, SC 29555
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Timmonsville Land: Build Your Dream
$45,000
2.17 Acres

Timmonsville Land: Build Your Dream

2.17-acre lot for dream home, no HOA, near Florence.

3305 Bumm Drive, Timmonsville, SC 29161
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Prime Land in Pamplico, SC
$99,000
2.00 Acres

Prime Land in Pamplico, SC

Two-acre commercial land with high visibility and road frontage.

S Pamplico Highway, Pamplico, SC 29583
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9.75 Acre Land Parcel
$149,000
9.75 Acres

9.75 Acre Land Parcel

Residential land available in Johnsonville, South Carolina.

Lot 3 Sheila Dr., Johnsonville, SC 29555
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Lake City Acreage For Sale
$155,000
13.32 Acres

Lake City Acreage For Sale

13.32 acres in Lake City, SC, ideal for development.

13.32 Ac - 1014 W Highway 378 Bypass, Lake City, SC 29560
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Land Near Walmart Market
$90,000
0.22 Acres

Land Near Walmart Market

Commercial land for sale next to Walmart Market.

2416 W Delmae Dr, Florence, SC 29501
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Vacant Land in Florence, SC
Contact for pricing

Vacant Land in Florence, SC

Land for sale by online auction in Florence, SC.

408 N Schofield St, Florence, SC 29501
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Effingham Acreage with Warehouse and Pond
$1,149,000
158.59 Acres

Effingham Acreage with Warehouse and Pond

158+ acres with warehouse, pond, and development potential near Florence.

1315 Hill Harrell Road, Effingham, SC 29541
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Prime Commercial Land Opportunity
$129,900
4.00 Acres

Prime Commercial Land Opportunity

4-acre commercial land in high-traffic Florence County.

TBD W Leggs Cir, Florence, SC 29501
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Cleared and Wooded Land
$114,900
7.11 Acres

Cleared and Wooded Land

7.11 acres of land in Johnsonville, South Carolina.

Lot 4 Sheila Dr., Johnsonville, SC 29555
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Florence Commercial Land For Sale
$49,900
840 SF

Florence Commercial Land For Sale

B-6 zoned property with commercial and redevelopment options.

720 S Barringer, Florence, SC 29506
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Florence Commercial Land For Sale
$396,396
0.91 Acres

Florence Commercial Land For Sale

0.91 acre commercial land parcel in Florence, South Carolina.

Presbyterian Road, Florence, SC 29501
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20 Acres Vacant Land
$144,000
20.00 Acres

20 Acres Vacant Land

20-acre tract suitable for small farm or recreational use.

00 East Myrtle Beach Highway TRACT 4, Johnsonville, SC 29555
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25 Acres Near Great Pee Dee
$180,000
25.00 Acres

25 Acres Near Great Pee Dee

25-acre tract suitable for small farm or recreational use.

00 East Myrtle Beach Highway TRACT 3, Johnsonville, SC 29555
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Timmonsville Wooded Lot Near I-95
$59,900
9.00 Acres

Timmonsville Wooded Lot Near I-95

9-acre wooded lot suitable for hunting, recreation, or building.

0 S Hill Rd, Timmonsville, SC 29161
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Vacant Land in Florence, SC
Contact for pricing

Vacant Land in Florence, SC

Vacant lot, previously had 2 mobile homes.

417 N Schofield St, Florence, SC 29501
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Residential Lot in Florence, SC
Contact for pricing
0.27 Acres

Residential Lot in Florence, SC

Residential lot suitable for single-family home in Florence, SC.

403 S 1st Street, Florence, SC 29506
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Florence County, SC Land Investment Opportunities Market Analysis

Explore 163 land for sale in Florence County, SC, showcased through 163 active listings on our real estate platform. These investment opportunities span a total of 60,319,710 square feet of properties for sale, with an estimated market value of $18,764,897.

Sale prices for lots in Florence County, SC start at $32,500, averaging $307,621, and reaching up to $1,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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