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Florence County, SC Land for Sale

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225 properties
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Commercial Land Along Four-Lane Corridor
Updated: Jun 3
Commercial Land Along Four-Lane Corridor

917 S Cashua Drive, Florence, SC 29501

$850,000
4.76 AC lot
4.76‑acre commercial land parcel
Approximately 30,700 vehicles per day (AADT) reported by SCDOT
Located along a four‑lane corridor near Second Loop Road and South Cashua crossroads
High, level site near Walmart Neighborhood Market, grocery, gas, and restaurant businesses
Potential applications include retail, quick‑service restaurant, medical, automotive, and multi‑tenant commercial uses
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Cleared Commercial Land
Updated: Jul 11
Cleared Commercial Land

207 S Irby St., Florence, SC 29501

$699,000
0.52 AC lot
0.52‑acre commercial land parcel
Level, cleared site
Utilities available
Commercial zoning
Located at 207 S Irby St., Florence, SC 29501
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Commercial Land at Interstate Exit
Commercial Land at Interstate Exit

Cale Yarborough HWY, Timmonsville, SC 29161

$225,000
3.03 AC lot

Commercial-zoned acreage with public water and sewer access at a major interstate interchange.

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Commercial Land with Utilities
Commercial Land with Utilities

3104 Hoffmeyer Road, Florence, SC 29501

$1,600,000
4 sqft

Public sewer is installed, with water, electricity, and high-speed internet available for future development.

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Unzoned Commercial Land Tract
Unzoned Commercial Land Tract

880 Freedom Blvd, Florence, SC 29506

$1,900,000
59.44 AC lot

Large unzoned tract with existing water and sewer infrastructure and flexible land-use potential.

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Highway Commercial Land
Highway Commercial Land

791 S Ron McNair Blvd., Lake City, SC 29560

$599,000
2.90 AC lot

Commercial land with GC zoning, planned structure removal, and access to an established industrial and commercial corridor.

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Recreation Land with Warehouse
Recreation Land with Warehouse

1315 Hill Harrell Road, Effingham, SC 29541

$1,149,000
158.59 AC lot

Expansive recreational tract with cleared ground, a stocked pond, utility service, and substantial covered improvements.

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Prime Commercial Site on Highway
Prime Commercial Site on Highway

791 South Ron McNair Boulevard, Lake City, SC 29560

$599,000
2.90 AC lot

Development opportunity in high-traffic commercial corridor near industrial area.

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Corner Commercial Land
Corner Commercial Land

360 S Ron McNair Blvd, Lake City, SC 29560

$59,900
1,200 sqft 0.12 AC lot

Corner commercial parcel with brick construction, concrete flooring, and central air.

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Commercial Land Parcel
Commercial Land Parcel

1714 2nd Loop Rd., Florence, SC 29501

$1,650,000
4.03 AC lot

Vacant tract with FV zoning and convenient access from 2nd Loop Road.

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Signalized Intersection Commercial Land
Signalized Intersection Commercial Land

2365 Pamplico Highway, Florence, SC 29505

$525,000

Unzoned commercial parcel with highway exposure and access to a major retail corridor.

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B-6 Zoned Commercial Land
B-6 Zoned Commercial Land

720 S Barringer Street, Florence, SC 29506

$47,900
840 sqft 0.17 AC lot

Commercial parcel near two Florence medical centers, offered in its existing condition for redevelopment or other commercial plans.

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Corner Commercial Land
Corner Commercial Land

635 N Coit St., Florence, SC 29501

$265,000
0.91 AC lot

Flat, buildable commercial site with utilities available at a prominent corner location.

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Commercial Land with Bus Terminal
Commercial Land with Bus Terminal

611 S Irby St, Florence, SC 29501

Contact for pricing
5,500 sqft 1.05 AC lot

1.05-acre site with 5,500 SF bus terminal building.

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Hunting and Homesite Land Tract
Hunting and Homesite Land Tract

9.58 Acres - S Deerfield Rd., Johnsonville, SC 29555

$114,960
9.58 AC lot

A 9.58-acre Ag-zoned tract with open high-field acreage and mixed woods with wetlands.

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Cleared Homesite with Wooded Hunting Land
Cleared Homesite with Wooded Hunting Land

Sheila Dr. lot: 3, Johnsonville, SC 29555

$129,900
9.75 AC lot

A 9.75-acre tract with a cleared front area, wooded remainder, and wetlands at the back for outdoor recreation.

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Hotel Concept Development Land
Hotel Concept Development Land

2423 David H McLeod Blvd, Florence, SC 29501

Contact for pricing
7,000 sqft

Concept development includes an approximate 90-room select-service hotel and a 5,000–7,000 SF flexible commercial/restaurant pad.

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Unzoned Development Acreage with Utilities
Unzoned Development Acreage with Utilities

1829 S Pamplico Hwy., Pamplico, SC 29583

$168,900
9.06 AC lot

About 9 acres of mostly cleared unzoned land with water and electric hookups plus a poured house pad.

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Residential Development Land Parcel
Residential Development Land Parcel

Lot 3 Sheila Drive, Johnsonville, SC 29555

$129,900
9.75 AC lot

Cleared 9.75-acre lot on Sheila Drive with a tree line and beaver pond, allowing mobile or stick-built homes.

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Hunting Land with Open Field
Hunting Land with Open Field

17.74 Acres - S Deerfield Rd., Johnsonville, SC 29555

$177,400
17.74 AC lot

Agricultural-zoned acreage combines elevated open ground with wooded areas and wetlands for recreational use.

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Florence Commercial Development Opportunity
Florence Commercial Development Opportunity

2621 West Palmetto Street, Florence, SC 29501

Contact for pricing
4.54 AC lot

4.54 acre commercial parcel on high-traffic corridor.

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Residential Lot in Desirable Florence
Residential Lot in Desirable Florence

1525 Cherokee Rd., Florence, SC 29501

$165,000
0.50 AC lot

Corner lot in established Florence neighborhood, convenient to amenities.

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Zoned NZ Development Land
Zoned NZ Development Land

Pygatt Rd/ 2222 1/2 W Cummings Rd, Effingham, SC 29541

$170,000

Commercial land zoned NZ, offering flexible development possibilities for land and office-oriented endeavors.

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Commercial Land Development Site
Commercial Land Development Site

3312 Meadors Road, Florence, SC 29501

$1,500,000
7.27 AC lot

Level, buildable acreage near I-95 with utilities available nearby.

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Florence County, SC Land Market Trends and Statistics

Explore 225 land for sale in Florence County, SC, showcased through 225 active listings on our real estate platform. These investment opportunities span a total of 81,929,861 square feet of properties for sale, with an estimated market value of $38,026,597.

Sale prices for lots in Florence County, SC start at $32,725, averaging $417,874, and reaching up to $4,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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