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Florence County, SC Land for Sale

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156 properties
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Vacant Farm-Zoned Development Land
Updated: Jul 8
Vacant Farm-Zoned Development Land

1714 2nd Loop Rd., Florence, SC 29501

$1,650,000
4.03 AC lot
4.04‑acre vacant parcel on one of Florence’s most active commercial corridors
Zoned Farm Vacant (FV), offering flexibility for future development options
Convenient access to West Second Loop Road
Surrounded by an established commercial medical facility at 1706 2nd Loop Road and a shopping plaza across the way
Generous acreage for new construction, parking, and site planning
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Commercial Land with Water and Sewer
Updated: May 16
Commercial Land with Water and Sewer

Cale Yarborough HWY, Timmonsville, SC 29161

$225,000
3.03 AC lot
Commercial property located immediately off Exit 150 at the intersection of I‑95 and Cale Yarborough Highway
Easement provides access to a smaller rear section, creating additional income‑producing lease potential
Rear section could be leased for uses such as a cellular tower, utility installation, billboard placement, or other small commercial leases
Public water and sewer available to the property
Site supports a range of commercial development including retail, hospitality, restaurants, travel services, fuel stations, storage, or mixed‑use
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Buildable Retail Development Land
Buildable Retail Development Land

3312 Meadors Road, Florence, SC 29501

$1,500,000
7.27 AC lot

Level, buildable two-parcel land package suited for a range of retail and service-oriented development uses.

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Florence Commercial Development Opportunity
Florence Commercial Development Opportunity

2621 West Palmetto Street, Florence, SC 29501

$1,200,000
4.54 AC lot

4.54 acre commercial parcel on high-traffic corridor.

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Development-Ready Commercial Land Site
Development-Ready Commercial Land Site

917 S Cashua Drive, Florence, SC 29501

$980,000
4.76 AC lot

4.76-acre B3-zoned parcel on a four-lane corridor with SCDOT-reported traffic near major daily-use anchors.

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Prime Commercial Land Opportunity
Prime Commercial Land Opportunity

791 S Ron McNair Blvd., Lake City, SC 29560

$599,000
2.90 AC lot

2.9-acre commercial site in Lake City, SC.

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Cleared Homesite with Wooded Hunting Land
Cleared Homesite with Wooded Hunting Land

Sheila Dr. lot: 3, Johnsonville, SC 29555

$129,900
9.75 AC lot

A 9.75-acre tract with a cleared front area, wooded remainder, and wetlands at the back for outdoor recreation.

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Commercial Land with Bus Terminal
Commercial Land with Bus Terminal

611 S Irby St, Florence, SC 29501

$395,000
5,500 sqft 1.05 AC lot

1.05-acre site with 5,500 SF bus terminal building.

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Cleared Level Commercial Land Lot
Cleared Level Commercial Land Lot

207 S Irby St., Florence, SC 29501

$750,000
0.52 AC lot

Level, cleared commercial lot with utilities available in Florence, SC.

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Unzoned Land with Poured House Pad
Unzoned Land with Poured House Pad

1829 S Pamplico Hwy., Pamplico, SC 29583

$178,900
9.06 AC lot

Unzoned 9-acre parcel with water and electric available and a poured house pad ready for further development.

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Prime Commercial Site on Highway
Prime Commercial Site on Highway

791 S Ron McNair Blvd, Lake City, SC 29560

$599,000
2.90 AC lot

Development opportunity in high-traffic commercial corridor near industrial area.

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Industrial Property with Warehouse and Pond
Industrial Property with Warehouse and Pond

1315 Hill Harrell Road, Effingham, SC 29541

$1,149,000
158.59 AC lot

Large acreage with a metal warehouse, finished back room, roll-up door, and a stocked pond with dock.

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Corner Commercial Development Lot
Corner Commercial Development Lot

360 S Ron McNair Blvd, Lake City, SC 29560

$59,900
1,200 sqft 0.12 AC lot

Corner commercial lot on a major route between Florence and Charleston, suited for office, retail, or restaurant development.

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Vacant Commercial Development Land
Vacant Commercial Development Land

1714 W 2nd Loop Rd., Florence, SC 29501

$1,650,000

A 4.04-acre vacant parcel zoned Farm Vacant (FV) with convenient access to W 2nd Loop Road.

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Recreation and Farmland Tract
Recreation and Farmland Tract

711 Cade Rd., Lake City, SC 29560

$515,000
66.00 AC lot

A rural land tract with approximately 30 acres of cropland, 39 acres of wetlands, and an on-site 3-bedroom home.

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Commercial Land Opportunity
Commercial Land Opportunity

W Leggs Cir, Florence, SC 29501

$129,900
4.00 AC lot

4-acre commercial land in Florence County, positioned in a high-traffic area for a wide range of business uses.

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Zoned NZ Development Land
Zoned NZ Development Land

Pygatt Rd/ 2222 1/2 W Cummings Rd, Effingham, SC 29541

$170,000

Commercial land zoned NZ, offering flexible development possibilities for land and office-oriented endeavors.

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B-6 Zoned Commercial Land Opportunity
B-6 Zoned Commercial Land Opportunity

720 S Barringer Street, Florence, SC 29506

$47,900
840 sqft 0.17 AC lot

B-6 zoned parcel suited for a range of commercial development options.

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Commercial Land For Sale
Commercial Land For Sale

2819 E Palmetto Street, Florence, SC 29501

$166,000
1.98 AC lot

1.98 acre commercial land with utilities in Florence, SC.

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Residential Land with Septic Permit
Residential Land with Septic Permit

Cockfield Road, Scranton, SC 29591

$240,000
29.36 AC lot

29.36+/- acres with road frontage and an engineered septic permit, plus power run to a started homesite.

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South Irby Street Commercial Lot
South Irby Street Commercial Lot

623 South Irby Street, Florence, SC 29501

$255,000
0.46 AC lot

0.46 acre lot suitable for retail or office development.

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Residential Lot in Desirable Florence
Residential Lot in Desirable Florence

1525 Cherokee Rd., Florence, SC 29501

$165,000
0.50 AC lot

Corner lot in established Florence neighborhood, convenient to amenities.

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Prime Commercial Lot in Florence
Prime Commercial Lot in Florence

3104 Hoffmeyer Road, Florence, SC 29501

$1,600,000
4.12 AC lot

Strategically located 4.12-acre commercial lot in a high-growth area.

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Riverfront Recreation Peninsula Land
Riverfront Recreation Peninsula Land

Allison Landing Road, Johnsonville, SC 29555

$880,000
200.00 AC lot

A 200-acre river peninsula with upland homesite/cabin areas and abundant wildlife, including natural duck-holding habitat.

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Florence County, SC Land Market Trends and Statistics

Explore 156 land for sale in Florence County, SC, showcased through 156 active listings on our real estate platform. These investment opportunities span a total of 13,636 square feet of properties for sale, with an estimated market value of $3,912,700.

Sale prices for lots in Florence County, SC start at $47,900, averaging $558,957, and reaching up to $2,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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