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    Pickens County, SC Commercial Real Estate for Sale

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    Wedding Venue With Open Event Space
    Updated: Aug 21
    Wedding Venue With Open Event Space

    3825 Saluda Dam Road, Easley, SC 29640

    $2,000,000
    2.13 AC lot
    Approximately 22,850+/- SF heated and cooled building on 2.13+/- acres
    8,400 SF high‑ceiling open room measuring 80' * 105'
    15,625+/- SF main level plus approximately 7,225 SF upstairs
    Approximately 23 classrooms or offices across both levels
    Approximately 140 total parking spaces, including 100 through a recorded shared‑parking agreement
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    Multi-Tenant Retail Building
    Updated: Jun 20
    Multi-Tenant Retail Building

    203 Pendleton Road, Clemson, SC 29631

    $1,500,000
    0.88 AC lot
    Approximately +/-7,000 SF of finished commercial space
    Additional +/-7,000 unfinished basement
    Multi‑tenant retail configuration
    Approximately 0.88 acres
    Located on Pendleton Road (SC‑93)
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    Freestanding Restaurant with Private Rooms
    Freestanding Restaurant with Private Rooms

    212 Harley Court, Easley, SC 29642

    $399,999
    1.93 AC lot

    Existing restaurant layout includes private dining rooms and on-site parking.

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    Conditioned Fitness Facility with Training Areas
    Conditioned Fitness Facility with Training Areas

    198 Couch Lane, Easley, SC 29642

    $865,000
    12,020 sqft 1.00 AC lot

    Flexible commercial building with open-span activity space, offices, storage, restrooms, and a drive-through door.

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    Retail Space with Display Fixtures
    Retail Space with Display Fixtures

    701 W Main Street, Easley, SC 29642

    $350,000
    0.50 AC lot

    The building includes display fixtures, shelving, security systems, and parking at both the front and rear.

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    Commercial Corner Land
    Commercial Corner Land

    2341 Dacusville Highway, Easley, SC 29640

    $845,000
    9.41 AC lot

    Public water, electricity, and fiber are available at this corner site.

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    Commercial Land with Highway Frontage
    Commercial Land with Highway Frontage

    2663 Gentry Memorial Highway, Pickens, SC 29671

    $1,200,000
    3.24 AC lot

    Commercial land with public water and road frontage.

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    Historic Two-Story Retail Building
    Historic Two-Story Retail Building

    108 NW Main St, Easley, SC 29640

    $750,000
    8,296 sqft

    Two-story brick building with two street-facing entrances for independent operation of separate units.

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    Corner Commercial Land
    Corner Commercial Land

    Ruhamah Road, Liberty, SC 29657

    $374,000
    5.00 AC lot

    Commercial land with public water and frontage along two roads near Liberty High School.

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    Commercial Land Near Highway Access
    Commercial Land Near Highway Access

    Farmers Hill Road, Liberty, SC 29657

    $117,500
    3.36 AC lot

    Commercial parcel with public water and access within one mile of Hwy 123.

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    Multi-Tenant Retail Building
    Multi-Tenant Retail Building

    203 Pendleton Road, Clemson, SC 29631

    $1,500,000
    7,000 sqft 0.88 AC lot

    Multi-tenant retail building with ample parking and an unfinished basement, located on highly visible Pendleton Road.

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    Specialty Property with Metal Roof
    Specialty Property with Metal Roof

    141 City View Circle, Pickens, SC 29671

    $399,000
    0.57 AC lot

    Brick-and-metal-siding facility with central air, electric cooling, and natural-gas heating.

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    Corner-Lot Religious Facility
    Corner-Lot Religious Facility

    439 N East Main Street, Easley, SC 29640

    $475,000
    0.52 AC lot

    Existing Masonic lodge use occupies a corner parcel with potential for development or operational expansion.

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    Multi-Tenant Office Condominium Units
    Multi-Tenant Office Condominium Units

    1824 E Main St, Easley, SC 29640

    $210,000
    7,808 sqft 0.70 AC lot

    Four office condominium units in Easley, with two vacant for immediate occupancy and two occupied under existing leases.

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    Commercial Land Near Highway Access
    Commercial Land Near Highway Access

    4120 Calhoun Memorial Highway, Easley, SC 29640

    $525,000
    4.25 AC lot

    Level to rolling acreage sits near Highway 123 with regional access toward Easley, I-85, and Greenville.

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    Commercial Land Near Retail
    Commercial Land Near Retail

    106 Roberts Drive, Pickens, SC 29671

    $570,000
    1.55 AC lot

    Commercial land with public water service near established apartments, retail, and restaurant uses.

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    Flex Property with Drive-In Access
    Flex Property with Drive-In Access

    303 Mossie Smith Rd, Easley, SC 29642

    $550,000
    3,580 sqft 0.70 AC lot

    A conditioned office component complements warehouse space in a flexible industrial layout.

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    Commercial Land with Road Frontage
    Commercial Land with Road Frontage

    Cardinal Drive, Easley, SC 29642

    $1,900,000
    17.22 AC lot

    Wooded acreage outside Easley with access near Highways 153 and 123.

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    Spa & Wellness Building
    Spa & Wellness Building

    339 W Main St, Easley, SC 29640

    $425,000
    2,800 sqft

    Two-level commercial property with flexible rooms, original hardwood floors, high ceilings, and abundant natural light.

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    Pastureland With Barn
    Pastureland With Barn

    1549 Midway Road, Pickens, SC 29671

    $606,000
    40.40 AC lot

    Agricultural acreage with pasture, utility connections, fencing, and an open-sided barn.

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    Live-Work Property with Detached Shop
    Live-Work Property with Detached Shop

    155 Farrs Bridge Rd, Pickens, SC 29671

    $225,000
    1,500 sqft 0.47 AC lot

    Two-bedroom residence with a separate shop and covered area supports combined personal and commercial use.

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    Easley SC Land For Sale
    Easley SC Land For Sale

    Cardinal Drive, Easley, SC 29642

    $1,900,000
    17.22 AC lot

    17+ acre commercial land opportunity near Easley, South Carolina.

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    Warehouse/Showroom near Highway 153
    Warehouse/Showroom near Highway 153

    600 Ross Avenue, Easley, SC 29640

    $875,000
    8,100 sqft

    8,100 SF warehouse/showroom located off Highway 153 in Easley, SC.

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    Retail Storefront with Parking
    Retail Storefront with Parking

    701 W Main Street, Easley, SC 29642

    $350,000

    Includes display cases, shelving, and security systems for retail operations.

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    Pickens County, SC Commercial Real Estate Market Trends and Statistics

    Explore 122 commercial real estate for sale in Pickens County, SC, showcased through 122 active listings on our real estate platform. These investment opportunities span a total of 18,227,606 square feet of properties for sale, with an estimated market value of $93,919,150.

    Sale prices for business properties in Pickens County, SC start at $43,000, averaging $1,020,860, and reaching up to $5,261,543 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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