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    Pickens County, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    106 results
    Pickens Office Investment Opportunity
    $350,000
    0.16 Acres

    Pickens Office Investment Opportunity

    113 Court Street, Pickens, SC 29671

    Commercial office building near Pickens County Court House.

    • Prime commercial location next to the Pickens County Court House.
    • Two rental units provide additional income, with one unit currently leased through June 2027 at $750/month.
    • Unique architectural features including soaring wood ceilings, solid wood beams, brick wall accents & flooring, and a double brick fireplace.
    • Flexible floor plan with multiple offices, meeting room, conference room, kitchenette, reception area, and open work areas.
    • Private brick courtyard provides natural light and an appealing outdoor space.
    Updated: Apr 14
    View details
    Multi-Use Property in Easley, SC
    $175,000
    0.34 Acres

    Multi-Use Property in Easley, SC

    612 W Main Street, Easley, SC 29640

    Versatile property near downtown Easley with commercial and residential potential.

    • High‑visibility location less than a mile from downtown Easley and minutes from The Silos.
    • Offers both commercial and residential use potential.
    • Large, open space with a wood‑burning fireplace suitable for various business purposes.
    • Versatile layout with rooms adaptable as private offices, meeting spaces, or client areas.
    • Secluded room with updated lighting and fresh paint, ideal for a private office or executive suite.
    Updated: Apr 15
    View details
    Easley Commercial Opportunity on Highway
    $249,900
    0.49 Acres

    Easley Commercial Opportunity on Highway

    High-visibility commercial lot near downtown Easley with office building.

    609 E Main Street, Easley, SC 29640
    View details
    Easley Commercial Property on Highway
    $249,900
    0.49 Acres

    Easley Commercial Property on Highway

    High-visibility commercial lot near downtown Easley with office building.

    609 E Main Street, Easley, SC 29640
    View details
    Retail Opportunity in Pickens, SC
    $350,000

    Retail Opportunity in Pickens, SC

    Retail space available for purchase in Pickens, South Carolina.

    131/133 W Main Street, Pickens, SC 29671
    View details
    Prime Acreage in Pickens, SC
    $570,000
    1.55 Acres

    Prime Acreage in Pickens, SC

    Acreage in a rapidly growing area of Pickens County.

    106 Roberts Drive, Pickens, SC 29671
    View details
    Commercial Land in Easley, SC
    $449,900
    0.50 Acres

    Commercial Land in Easley, SC

    Commercial land with investment potential in the heart of Easley.

    329 Prince Perry Road, Easley, SC 29640
    View details
    Easley Commercial Land Opportunity
    $52,500
    0.38 Acres

    Easley Commercial Land Opportunity

    0.38 acres of commercial land in a growing area.

    109 Franklin Square Way, Easley, SC 29642
    View details
    Easley Commercial Land Opportunity
    $52,500
    0.38 Acres

    Easley Commercial Land Opportunity

    0.38 acres of commercial land in a growing area.

    109 Franklin Square Way, Easley, SC 29642
    View details
    Prime Land in Pickens, SC
    $1,200,000
    3.24 Acres

    Prime Land in Pickens, SC

    3.24 acres in a rapidly growing area with development potential.

    2663 Gentry Memorial Highway, Pickens, SC 29671
    View details
    Land Borders Southern Oaks Golf
    $999,900
    4.27 Acres

    Land Borders Southern Oaks Golf

    4.27 acres bordering golf course, ideal for homes or business.

    8426 81 N Highway, Easley, SC 29642
    View details
    Easley Commercial Land For Sale
    $605,000
    5.70 Acres

    Easley Commercial Land For Sale

    5.7 acre commercial land available in Easley, South Carolina.

    533 Crest Drive, Easley, SC 29640
    View details
    Land Borders Southern Oaks Golf
    $999,900
    4.27 Acres

    Land Borders Southern Oaks Golf

    4.27 acres bordering golf course, ideal for development.

    8426 81 N Highway, Easley, SC 29642
    View details
    Easley Commercial Land Opportunity
    $275,000
    2.00 Acres

    Easley Commercial Land Opportunity

    2-acre commercial land with existing building, development potential.

    2625 Farrs Bridge Road, Easley, SC 29640
    View details
    Downtown Easley Retail Opportunity
    Contact for pricing

    Downtown Easley Retail Opportunity

    2,000 SF retail space in downtown Easley, SC.

    106 N Pendleton Street, Easley, SC 29640
    View details
    Commercial Building on Highway 123
    $1,349,990
    0.48 Acres

    Commercial Building on Highway 123

    Commercial building in Clemson with ample parking and high traffic.

    990 Tiger Boulevard, Clemson, SC 29631
    View details
    Easley Commercial Land For Sale
    $55,000
    0.39 Acres

    Easley Commercial Land For Sale

    0.39 acre commercial lot with road frontage in Easley, SC.

    315 Gentry Memorial Highway, Easley, SC 29640
    View details
    Prime Development Site in Easley
    $1,615,000
    17.00 Acres

    Prime Development Site in Easley

    17+/- acres for development near Highway 123 in Easley, SC.

    00 Prince Perry Road, Easley, SC 29640
    View details
    Land Parcels in Dacusville Community
    $255,000
    8.60 Acres

    Land Parcels in Dacusville Community

    Mini-farms with mountain views near Greenville, Easley, and Pickens.

    01 Hood Road, Easley, SC 29640
    View details
    Easley Commercial Site For Sale
    $1,900,000
    17.22 Acres

    Easley Commercial Site For Sale

    17+ acre commercial site near Easley, SC.

    00 Cardinal Drive, Easley, SC 29642
    View details
    Easley SC Acreage For Sale
    $1,900,000
    17.22 Acres

    Easley SC Acreage For Sale

    17+ acres near Easley, SC, ideal for development.

    00 Cardinal Drive, Easley, SC 29642
    View details
    Clemson Tailgating Lot For Sale
    $50,000
    0.01 Acres

    Clemson Tailgating Lot For Sale

    Tailgating lot near Clemson Football, behind the Esso Club.

    101 Oak Street, Clemson, SC 29630
    View details
    Liberty SC Commercial Site
    $118,500
    3.00 Acres

    Liberty SC Commercial Site

    Commercial site available in Liberty, South Carolina.

    00 Farmers Hill Road, Liberty, SC 29657
    View details
    Commercial Office Building Investment Opportunity
    $350,000
    2,400 SF

    Commercial Office Building Investment Opportunity

    Commercial office building near Pickens County Court House for sale.

    113 Court Street, Pickens, SC 29671
    View details

    Pickens County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 106 commercial real estate for sale in Pickens County, SC, showcased through 106 active listings on our real estate platform. These investment opportunities span a total of 9,973,497 square feet of properties for sale, with an estimated market value of $32,590,836.

    Sale prices for business properties in Pickens County, SC start at $50,000, averaging $835,662, and reaching up to $4,052,500 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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