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    Florence County, SC Commercial Land for Sale

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    63 properties
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    Commercial Land Along Four-Lane Corridor
    Updated: Jun 3
    Commercial Land Along Four-Lane Corridor

    917 S Cashua Drive, Florence, SC 29501

    $850,000
    4.76 AC lot
    4.76‑acre commercial land parcel
    Approximately 30,700 vehicles per day (AADT) reported by SCDOT
    Located along a four‑lane corridor near Second Loop Road and South Cashua crossroads
    High, level site near Walmart Neighborhood Market, grocery, gas, and restaurant businesses
    Potential applications include retail, quick‑service restaurant, medical, automotive, and multi‑tenant commercial uses
    View details
    Cleared Commercial Land
    Updated: Jul 11
    Cleared Commercial Land

    207 S Irby St., Florence, SC 29501

    $699,000
    0.52 AC lot
    0.52‑acre commercial land parcel
    Level, cleared site
    Utilities available
    Commercial zoning
    Located at 207 S Irby St., Florence, SC 29501
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    Corner Commercial Land
    Corner Commercial Land

    TBD Hwy 51 Pamplico Hwy, Florence, SC 29505

    $250,000
    1.30 AC lot

    B-3-zoned parcel positioned at the intersection of Pamplico Hwy and E Broach Street in Florence.

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    Commercial Land with Utilities
    Commercial Land with Utilities

    3104 Hoffmeyer Road, Florence, SC 29501

    $1,600,000
    4 sqft

    Public sewer is installed, with water, electricity, and high-speed internet available for future development.

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    Unzoned Commercial Land
    Unzoned Commercial Land

    880 Freedom Boulevard, Florence, SC 29506

    $1,800,000
    59.44 AC lot

    Unzoned commercial tract with water and sewer on site and flexibility for varied land-use plans.

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    Commercial Land at Interstate Exit
    Commercial Land at Interstate Exit

    Cale Yarborough HWY, Timmonsville, SC 29161

    $225,000
    3.03 AC lot

    Commercial-zoned acreage with public water and sewer access at a major interstate interchange.

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    Corner Commercial Land
    Corner Commercial Land

    360 S Ron McNair Blvd, Lake City, SC 29560

    $59,900
    1,200 sqft 0.12 AC lot

    Corner commercial parcel with brick construction, concrete flooring, and central air.

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    Signalized Intersection Commercial Land
    Signalized Intersection Commercial Land

    2365 Pamplico Highway, Florence, SC 29505

    $525,000

    Unzoned commercial parcel with highway exposure and access to a major retail corridor.

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    Highway Commercial Land
    Highway Commercial Land

    791 S Ron McNair Blvd., Lake City, SC 29560

    $599,000
    2.90 AC lot

    Commercial land with GC zoning, planned structure removal, and access to an established industrial and commercial corridor.

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    Commercial Land Parcel
    Commercial Land Parcel

    1714 2nd Loop Rd., Florence, SC 29501

    $1,650,000
    4.03 AC lot

    Vacant tract with FV zoning and convenient access from 2nd Loop Road.

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    Vacant Commercial Development Land
    Vacant Commercial Development Land

    1714 2nd Loop Rd, Florence, SC 29501

    $1,650,000

    A 4.04-acre vacant parcel zoned Farm Vacant (FV) with convenient access to W 2nd Loop Road.

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    B-6 Zoned Commercial Land
    B-6 Zoned Commercial Land

    720 S Barringer Street, Florence, SC 29506

    $47,900
    840 sqft 0.17 AC lot

    Commercial parcel near two Florence medical centers, offered in its existing condition for redevelopment or other commercial plans.

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    Corner Commercial Land
    Corner Commercial Land

    635 N Coit St., Florence, SC 29501

    $265,000
    0.91 AC lot

    Flat, buildable commercial site with utilities available at a prominent corner location.

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    Commercial Land with Bus Terminal
    Commercial Land with Bus Terminal

    611 S Irby St, Florence, SC 29501

    Contact for pricing
    5,500 sqft 1.05 AC lot

    1.05-acre site with 5,500 SF bus terminal building.

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    Commercial Land Development Site
    Commercial Land Development Site

    3312 Meadors Road, Florence, SC 29501

    $1,500,000
    7.27 AC lot

    Level, buildable acreage near I-95 with utilities available nearby.

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    Signalized-Intersection Commercial Land
    Signalized-Intersection Commercial Land

    2365 Pamplico Hwy., Florence, SC 29505

    $525,000
    0.89 AC lot

    Unzoned commercial parcel with highway access near Florence’s medical district and retail corridor.

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    Prime Commercial Site on Highway
    Prime Commercial Site on Highway

    791 South Ron McNair Boulevard, Lake City, SC 29560

    $599,000
    2.90 AC lot

    Development opportunity in high-traffic commercial corridor near industrial area.

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    Commercial Land Parcel
    Commercial Land Parcel

    W Leggs Cir, Florence, SC 29501

    $129,900
    4.00 AC lot

    Four-acre commercial land parcel with CA zoning in Florence County.

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    Hotel Concept Development Land
    Hotel Concept Development Land

    2423 David H McLeod Blvd, Florence, SC 29501

    Contact for pricing
    7,000 sqft

    Concept development includes an approximate 90-room select-service hotel and a 5,000–7,000 SF flexible commercial/restaurant pad.

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    Commercial Land with Existing Structure
    Commercial Land with Existing Structure

    2931 Republic Avenue, Florence, SC 29501

    $75,000
    0.97 AC lot

    Commercially zoned land with an existing abandoned structure, offered for redevelopment in Florence.

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    Florence Commercial Development Opportunity
    Florence Commercial Development Opportunity

    2621 West Palmetto Street, Florence, SC 29501

    Contact for pricing
    4.54 AC lot

    4.54 acre commercial parcel on high-traffic corridor.

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    Corner Commercial Land
    Corner Commercial Land

    360 N Dargan St, Florence, SC 29501

    $75,000
    0.10 AC lot

    Commercially zoned corner parcel with a compact footprint in an established street setting.

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    Zoned NZ Development Land
    Zoned NZ Development Land

    Pygatt Rd/ 2222 1/2 W Cummings Rd, Effingham, SC 29541

    $170,000

    Commercial land zoned NZ, offering flexible development possibilities for land and office-oriented endeavors.

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    Highway-Frontage Commercial Land
    Highway-Frontage Commercial Land

    1644 US HIGHWAY 52, Scranton, SC 29591

    $299,000
    4.00 AC lot

    B-3 zoning and a second public-road entrance support commercial site planning.

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    Florence County, SC Commercial Land Market Trends and Statistics

    Explore 72 commercial land for sale in Florence County, SC, showcased through 63 active listings on our real estate platform. These investment opportunities span a total of 7,058,932 square feet of properties for sale, with an estimated market value of $18,204,297.

    Sale prices for commercial lots in Florence County, SC start at $32,725, averaging $606,809, and reaching up to $1,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Florence County Real Estate Agencies

    Realmo connects you with licensed Florence County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Coldwell Banker McMillan and Associates
    419 S.Coit Street Florence, SC 29501
    Phone: 18436017710
    CBFlorence.com
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