Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Lake City, SC Commercial Real Estate for Sale

    Notify Me
    List
    Map
    Columbia, SC Aiken, SC Beaufort, SC
    15 results
    Prime Commercial Lot on Highway
    $599,000
    2.90 Acres

    Prime Commercial Lot on Highway

    791 S Ron McNair Blvd., Lake City, SC 29560

    2.9-acre commercial site on S. Ron McNair Boulevard, Lake City.

    • ±2.90‑acre commercial site on S. Ron McNair Boulevard / Highway 52 corridor.
    • High traffic count of approximately 15,000 vehicles per day.
    • Located adjacent to Nan Ya Plastics, a major regional employer.
    • Clean Phase I Environmental Site Assessment in hand.
    • Site will be cleared of existing structures for redevelopment.
    Updated: Mar 9
    View details
    78.4 Acres with Cropland
    $515,000
    78.40 Acres

    78.4 Acres with Cropland

    711 Cade Rd., Lake City, SC 29560

    78.4-acre property featuring cropland, wetlands, and a 1,376-square-foot home.

    • 78.4‑acre property with diverse landscape.
    • Approximately 30 acres of cropland suitable for farming or leasing.
    • 39 acres of wetlands providing wildlife habitat and natural beauty.
    • 1,376‑square‑foot home with 3 bedrooms and 1 bathroom.
    • 3.9 acres of evergreen forest for privacy.
    Updated: Mar 28
    View details
    Downtown Lake City Commercial Lot
    $59,900
    1,200 SF

    Downtown Lake City Commercial Lot

    Commercial lot in downtown Lake City, South Carolina.

    360 S Ron McNair Blvd, Lake City, SC 29560
    View details
    Lake City Acreage For Sale
    $155,000
    13.32 Acres

    Lake City Acreage For Sale

    13.32 acres in Lake City, SC, ideal for development.

    13.32 Ac - 1014 W Highway 378 Bypass, Lake City, SC 29560
    View details
    Downtown Lake City Commercial Building
    $199,000
    2,500 SF

    Downtown Lake City Commercial Building

    2,500 sq ft commercial building in downtown Lake City.

    112 E Main St, Lake City, SC 29560
    View details
    Prime Commercial Site on Highway
    $599,000

    Prime Commercial Site on Highway

    Development opportunity in high-traffic commercial corridor near industrial area.

    791 S Ron McNair Blvd, Lake City, SC 29560
    View details
    Versatile Acreage in Lake City, SC
    $49,225
    19.60 Acres

    Versatile Acreage in Lake City, SC

    19.6-acre property ideal for recreation, investment, or building a home.

    TBD Green Rd., Lake City, SC 29560
    View details
    Commercial Lot in Lake City
    $160,000
    0.47 Acres

    Commercial Lot in Lake City

    0.47 acre commercial lot with rental income potential.

    0.47 Acres-TBD Sumter St., Lake City, SC 29560
    View details
    Commercial Lot in Downtown
    $59,900
    1,200 SF

    Commercial Lot in Downtown

    Commercial lot in a high-traffic downtown location.

    360 S Ron McNair Blvd, Lake City, SC 29560
    View details
    Commercial Land with Development Potential
    $200,000
    1.50 Acres

    Commercial Land with Development Potential

    Commercial land with frontage on US 52, development potential.

    356 S Ron McNair Blvd, Lake City, SC 29560
    View details
    Former Talon Zipper Plant
    $1,474,350
    105,000 SF

    Former Talon Zipper Plant

    Manufacturing/warehouse space on 20 acres near airport runway.

    701 South Ron McNair Boulevard |, Lake City, SC 29560
    View details
    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF

    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.

    215 John St, Lake City, SC
    View details
    Lake City Agricultural Land
    $221,000
    52.00 Acres

    Lake City Agricultural Land

    52 acre agricultural land with hunting and wildlife potential.

    52 Acres-TBD Vox Hwy., Lake City, SC 29560
    View details
    Vacant Restaurant with Drive-Thru
    $850,000
    2,819 SF

    Vacant Restaurant with Drive-Thru

    2,819 SF vacant restaurant with drive-thru for sale.

    147 S Ron McNair Blvd, Lake City, SC 29560
    View details
    Lake City Industrial Warehouse
    $5,900,000
    157,800 SF

    Lake City Industrial Warehouse

    Industrial warehouse property available for sale in Lake City.

    1051 E Main St, Lake City, SC
    View details
    Based on your search, we've compiled 568 Potential Opportunities for your consideration. Besides 15 Active listings in Lake City, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 549 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mechanic Shop on Highway 52
    $178,000
    3,150 SF

    Mechanic Shop on Highway 52

    Mechanic shop with three bays on heavily traveled Highway.

    321 N Williamsburg County Hwy., Kingstree, SC 29556
    View details
    Olanta Commercial Building on US 301
    $60,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114
    View details
    Cleared Land in Olanta, SC
    $153,000
    15.35 Acres

    Cleared Land in Olanta, SC

    15.35 acres of subdivided land with water and sewer access.

    Alice Myers Lane, Olanta, SC 29114
    View details
    Restaurant Opportunity on Corner Lot
    $199,900

    Restaurant Opportunity on Corner Lot

    Commercial property with restaurant equipment on 2.8-acre corner lot.

    8451 Hemingway Highway, Kingstree, SC 29556
    View details

    Explore Off-Market Properties in Lake City, SC

    Consider similar Off-Market properties in Lake City, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    121 Mcallister St

    121 Mcallister St

    WHOLESALE OUTLET, DISCOUNT STORE • 480 SF
    Value Estimation by Request
    121 Mcallister St, Lake City, SC 29560
    View details
    137 Mcallister St

    137 Mcallister St

    MOTEL • 11,592 SF
    Value Estimation by Request
    137 Mcallister St, Lake City, SC 29560-2423
    View details
    441 Church St

    441 Church St

    WAREHOUSE, STORAGE • 10,960 SF
    Value Estimation by Request
    441 Church St, Lake City, SC 29560-2645
    View details
    280 Old Georgetown Rd

    280 Old Georgetown Rd

    COMMERCIAL (GENERAL) • 5,976 SF
    Value Estimation by Request
    280 Old Georgetown Rd, Lake City, SC 29560-6401
    View details
    324 Main St

    324 Main St

    AUTO REPAIR, GARAGE • 5,440 SF
    Value Estimation by Request
    324 Main St, Lake City, SC 29560-2316
    View details
    2218 Lk City Hwy

    2218 Lk City Hwy

    WHOLESALE OUTLET, DISCOUNT STORE • 2,112 SF
    Value Estimation by Request
    2218 Lk City Hwy, Lake City, SC 29560
    View details
    221 Rodgers Ave

    221 Rodgers Ave

    OFFICE BUILDING • 2,929 SF
    Value Estimation by Request
    221 Rodgers Ave, Lake City, SC 29560-2151
    View details
    130 Acline St

    130 Acline St

    WHOLESALE OUTLET, DISCOUNT STORE • 11,656 SF
    Value Estimation by Request
    130 Acline St, Lake City, SC 29560-2130
    View details
    130 Acline St

    130 Acline St

    MEDICAL BUILDING • 2,052 SF
    Value Estimation by Request
    130 Acline St, Lake City, SC 29560-2633
    View details

    Lake City, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 564 commercial real estate for sale in Lake City, SC, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 272,241 square feet of properties for sale, with an estimated market value of $8,793,150.

    Sale prices for business properties in Lake City, SC start at $59,900, averaging $1,256,164, and reaching up to $5,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Commercial real estate for Sale Near Lake City, SC

    Popular Searches in Lake City, SC

    Most Searched ZIP Codes in Lake City, SC

    • 29560

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!