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    Lake City, SC Commercial Real Estate for Sale

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    Scranton, SC Cades, SC Coward, SC
    13 listings
    78.4 Acres Farmland with Home
    $515,000
    1,376 SF
    78.4 Acres Farmland with Home

    711 Cade Rd., Lake City, SC 29560

    78.4 acres featuring cropland, wetlands, and a 1,376-SF home.
    • 78.4‑acre property with diverse landscape.
    • Approximately 30 acres of cropland suitable for farming or leasing.
    • 39 acres of wetlands providing wildlife habitat and natural beauty.
    • 1,376‑square‑foot home with 3 bedrooms and 1 bathroom.
    • 3.9 acres of evergreen forest for privacy.
    Updated: Mar 28
    View details
    Prime Commercial Land Opportunity
    $599,000
    2.90 Acres
    Prime Commercial Land Opportunity

    791 S Ron McNair Blvd., Lake City, SC 29560

    2.9-acre commercial site in Lake City, SC.
    • Prime location on highly traveled S. Ron McNair Boulevard / Highway 52 corridor with approximately 15,000 vehicles per day.
    • +/-2.90‑acre commercial site suitable for a variety of commercial or light industrial uses.
    • Directly adjacent to Nan Ya Plastics, a major regional employer.
    • New MUSC healthcare facility nearby, increasing employment and service demand.
    • Clean Phase I Environmental Site Assessment in hand.
    Updated: Mar 9
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    Corner Commercial Development Lot
    $59,900
    1,200 SF
    Corner Commercial Development Lot

    Corner commercial lot on a major route between Florence and Charleston, suited for office, retail, or restaurant development.

    360 S Ron McNair Blvd, Lake City, SC 29560

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    Partially Cleared Acreage Tract
    $120,000
    13.32 Acres
    Partially Cleared Acreage Tract

    A RU-1 tract with cleared acreage for a homesite plus remaining wooded land for privacy and outdoor use.

    13.32 Ac - 1014 W Highway 378 Bypass, Lake City, SC 29560

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    Prime Commercial Site on Highway
    $599,000
    2.90 Acres
    Prime Commercial Site on Highway

    Development opportunity in high-traffic commercial corridor near industrial area.

    791 S Ron McNair Blvd, Lake City, SC 29560

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    Lake City Commercial Parking Lot
    $160,000
    0.47 Acres
    Lake City Commercial Parking Lot

    0.47 acre commercial lot with rental income potential.

    0.47 Acres-TBD Sumter St., Lake City, SC 29560

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    Former Talon Zipper Plant
    $1,474,350
    105,000 SF
    Former Talon Zipper Plant

    Manufacturing/warehouse space on 20 acres near airport runway.

    701 South Ron McNair Boulevard |, Lake City, SC 29560

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    Downtown Lake City Commercial Building
    $199,000
    2,500 SF
    Downtown Lake City Commercial Building

    2,500 sq ft commercial building in downtown Lake City.

    112 E Main St, Lake City, SC 29560

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    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF
    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.

    215 John St, Lake City, SC

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    Commercial Lot in Downtown
    $59,900
    1,200 SF
    Commercial Lot in Downtown

    Commercial lot in a high-traffic downtown location.

    360 S Ron McNair Blvd, Lake City, SC 29560

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    Lake City Industrial Warehouse
    $5,900,000
    157,800 SF
    Lake City Industrial Warehouse

    Industrial warehouse property available for sale in Lake City.

    1051 E Main St, Lake City, SC

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    Vacant Restaurant with Drive-Thru
    $850,000
    2,819 SF
    Vacant Restaurant with Drive-Thru

    2,819 SF vacant restaurant with drive-thru for sale.

    147 S Ron McNair Blvd, Lake City, SC 29560

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    Commercial Land with Development Potential
    $200,000
    1.50 Acres
    Commercial Land with Development Potential

    Commercial land with frontage on US 52, development potential.

    356 S Ron McNair Blvd, Lake City, SC 29560

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 13 Active listings in Lake City, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 59 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Olanta Commercial Building on US 301
    $60,000
    1,500 SF
    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114

    View details
    Cleared Land in Olanta, SC
    $153,000
    15.35 Acres
    Cleared Land in Olanta, SC

    15.35 acres of subdivided land with water and sewer access.

    Alice Myers Lane, Olanta, SC 29114

    View details
    3,000 SF Commercial Building For Sale
    $150,000
    3,000 SF
    3,000 SF Commercial Building For Sale

    3,000 SF building on 2 acres with equipment included.

    10126 Hemingway Hwy., Kingstree, SC 29556

    View details
    Restaurant Opportunity on Corner Lot
    $199,900
    2.80 Acres
    Restaurant Opportunity on Corner Lot

    Commercial property with restaurant equipment on 2.8-acre corner lot.

    8451 Hemingway Highway, Kingstree, SC 29556

    View details

    Off-Market Properties in Lake City, SC

    Consider similar Off-Market properties in Lake City, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    121 Mcallister St
    WHOLESALE OUTLET, DISCOUNT STORE
    480 SF Lot: 0.49 Acres
    Value Estimation by Request

    121 Mcallister St, Lake City, SC 29560

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    137 Mcallister St
    MOTEL
    11,592 SF Lot: 1.38 Acres
    Value Estimation by Request

    137 Mcallister St, Lake City, SC 29560-2423

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    441 Church St
    WAREHOUSE, STORAGE
    10,960 SF Lot: 0.49 Acres
    Value Estimation by Request

    441 Church St, Lake City, SC 29560-2645

    View details
    280 Old Georgetown Rd
    COMMERCIAL (GENERAL)
    5,976 SF Lot: 5.00 Acres
    Value Estimation by Request

    280 Old Georgetown Rd, Lake City, SC 29560-6401

    View details
    324 Main St
    AUTO REPAIR, GARAGE
    5,440 SF Lot: 1.18 Acres
    Value Estimation by Request

    324 Main St, Lake City, SC 29560-2316

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    2218 Lk City Hwy
    WHOLESALE OUTLET, DISCOUNT STORE
    2,112 SF Lot: 1.12 Acres
    Value Estimation by Request

    2218 Lk City Hwy, Lake City, SC 29560

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    221 Rodgers Ave
    OFFICE BUILDING
    2,929 SF Lot: 0.34 Acres
    Value Estimation by Request

    221 Rodgers Ave, Lake City, SC 29560-2151

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    130 Acline St
    WHOLESALE OUTLET, DISCOUNT STORE
    11,656 SF Lot: 0.31 Acres
    Value Estimation by Request

    130 Acline St, Lake City, SC 29560-2130

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    130 Acline St
    MEDICAL BUILDING
    2,052 SF Lot: 0.22 Acres
    Value Estimation by Request

    130 Acline St, Lake City, SC 29560-2633

    View details
    925 Main St
    OFFICE BUILDING
    2,100 SF Lot: 3.95 Acres
    Value Estimation by Request

    925 Main St, Lake City, SC 29560

    View details
    104 Main St
    WHOLESALE OUTLET, DISCOUNT STORE
    2,000 SF Lot: 0.07 Acres
    Value Estimation by Request

    104 Main St, Lake City, SC 29560-2627

    View details

    Lake City, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Lake City, SC, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 273,617 square feet of properties for sale, with an estimated market value of $9,308,150.

    Sale prices for business properties in Lake City, SC start at $59,900, averaging $1,163,518, and reaching up to $5,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 12K
    Population Growth (5Y) -7.6%
    Median Household Income $45,421
    College Educated 24.6%

    High-Yield Neighborhoods for Investment

    Identify Lake City submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29560 $407.5K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Florence County

    New Delisted

    Total CRE Inventory on Market (SF)

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