Commercial

Florence, SC Commercial Land for Sale

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Timmonsville, SC Effingham, SC Darlington, SC Coward, SC Marion, SC Latta, SC Pamplico, SC Lamar, SC
61 properties
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Vacant Farm-Zoned Development Land
Updated: Jul 8
Vacant Farm-Zoned Development Land

1714 2nd Loop Rd., Florence, SC 29501

$1,650,000
4.03 AC lot
4.04‑acre vacant parcel on one of Florence’s most active commercial corridors
Zoned Farm Vacant (FV), offering flexibility for future development options
Convenient access to West Second Loop Road
Surrounded by an established commercial medical facility at 1706 2nd Loop Road and a shopping plaza across the way
Generous acreage for new construction, parking, and site planning
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Buildable Retail Development Land
Updated: May 3
Buildable Retail Development Land

3312 Meadors Road, Florence, SC 29501

$1,500,000
7.27 AC lot
Two‑parcel commercial package totaling 7.27 acres
Located just off I‑95 with easy access
Directly across from a newly built Quick Trip store
Buildable property with utilities available nearby
Nearby commercial corridor with suitability for retail, service stations, and hospitality
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Development-Ready Commercial Land Site
Development-Ready Commercial Land Site

917 S Cashua Drive, Florence, SC 29501

$980,000
4.76 AC lot

4.76-acre B3-zoned parcel on a four-lane corridor with SCDOT-reported traffic near major daily-use anchors.

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Florence Commercial Development Opportunity
Florence Commercial Development Opportunity

2621 West Palmetto Street, Florence, SC 29501

$1,200,000
4.54 AC lot

4.54 acre commercial parcel on high-traffic corridor.

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Cleared Level Commercial Land Lot
Cleared Level Commercial Land Lot

207 S Irby St., Florence, SC 29501

$750,000
0.52 AC lot

Level, cleared commercial lot with utilities available in Florence, SC.

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Commercial Land Opportunity
Commercial Land Opportunity

W Leggs Cir, Florence, SC 29501

$129,900
4.00 AC lot

4-acre commercial land in Florence County, positioned in a high-traffic area for a wide range of business uses.

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B-6 Zoned Commercial Land Opportunity
B-6 Zoned Commercial Land Opportunity

720 S Barringer Street, Florence, SC 29506

$47,900
840 sqft 0.17 AC lot

B-6 zoned parcel suited for a range of commercial development options.

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Commercial Land with Bus Terminal
Commercial Land with Bus Terminal

611 S Irby St, Florence, SC 29501

$395,000
5,500 sqft 1.05 AC lot

1.05-acre site with 5,500 SF bus terminal building.

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Flat Corner Commercial Land
Flat Corner Commercial Land

635 N Coit St., Florence, SC 29501

$275,000
0.91 AC lot

Commercially zoned flat, buildable corner lot with utilities available.

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Florence Commercial Land For Sale
Florence Commercial Land For Sale

Presbyterian Road, Florence, SC 29501

$792,792
1.82 AC lot

1.82 acre commercial land near I-95 in Florence, SC.

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Vacant Commercial Development Land
Vacant Commercial Development Land

1714 W 2nd Loop Rd., Florence, SC 29501

$1,650,000

A 4.04-acre vacant parcel zoned Farm Vacant (FV) with convenient access to W 2nd Loop Road.

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Commercial Redevelopment Land Parcel
Commercial Redevelopment Land Parcel

2931 Republic Avenue, Florence, SC 29501

$75,000
0.97 AC lot

Nearly one-acre commercial-zoned lot in Florence, SC, sold as-is with an abandoned structure on-site.

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Florence Commercial Land For Sale
Florence Commercial Land For Sale

Presbyterian Road, Florence, SC 29501

$396,396
0.91 AC lot

0.91 acre commercial land parcel in Florence, South Carolina.

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Commercial Land For Sale
Commercial Land For Sale

2819 E Palmetto Street, Florence, SC 29501

$166,000
1.98 AC lot

1.98 acre commercial land with utilities in Florence, SC.

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Commercial Land at Signalized Intersection
Commercial Land at Signalized Intersection

2365 Pamplico Hwy., Florence, SC 29505

$525,000
0.89 AC lot

Unzoned commercial parcel with high-visibility access on Pamplico Highway, suited for a range of development concepts.

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Corner Commercial Land Parcel
Corner Commercial Land Parcel

360 N Dargan St, Florence, SC 29501

$75,000
0.10 AC lot

Corner lot zoned Commercial, suited for development or placement of a new commercial use in Florence.

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South Irby Street Commercial Lot
South Irby Street Commercial Lot

623 South Irby Street, Florence, SC 29501

$255,000
0.46 AC lot

0.46 acre lot suitable for retail or office development.

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Unzoned Land Near Florence
Unzoned Land Near Florence

6.54 Acres-TBD Alligator Rd., Florence, SC 29501

$255,000
6.54 AC lot

6.54 acres of unzoned land with potential.

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Prime Commercial Lot in Florence
Prime Commercial Lot in Florence

3104 Hoffmeyer Road, Florence, SC 29501

$1,600,000
4.12 AC lot

Strategically located 4.12-acre commercial lot in a high-growth area.

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Florence Commercial Land For Sale
Florence Commercial Land For Sale

Presbyterian Road, Florence, SC 29501

$278,784
0.64 AC lot

0.64 acre commercial land parcel in Florence, South Carolina.

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Prime Commercial Land Opportunity
Prime Commercial Land Opportunity

3312 Meadors Road, Florence, SC 29501

$1,500,000
7.27 AC lot

7.27 acres near I-95, ideal for commercial development.

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Prime Hotel Development Site
Prime Hotel Development Site

341 W Evans St, Florence, SC

Contact for pricing
1.00 AC lot

1-acre site ideal for hospitality near major medical centers.

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Five Lots in Residential Neighborhood
Five Lots in Residential Neighborhood

1506 Sandy Ln, Florence, SC 29501

$175,000
0.71 AC lot

Five lots zoned R-5A near multifamily housing.

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Florence Area Investment Opportunity
Florence Area Investment Opportunity

5723 E National Cemetery Rd, Florence, SC 29506

Contact for pricing

Prime land in Florence, SC, with development potential.

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Florence, SC Commercial Land Market Trends and Statistics

Explore 72 commercial land for sale in Florence, SC, showcased through 61 active listings on our real estate platform. These investment opportunities span a total of 11,236 square feet of properties for sale, with an estimated market value of $3,792,900.

Sale prices for commercial lots in Florence, SC start at $47,900, averaging $758,580, and reaching up to $2,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Commercial land 72
Residential land & home lots 12
Agricultural land / Farmland 1
Industrial land 1
Recreation land 1

Demographics Overview

Population 92K
Population Growth (5Y) -1.5%
Median Household Income $61,793
College Educated 17.4%

High-Yield Neighborhoods for Investment

Identify Florence submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
29501 $535.7K
29505 $672K
29506 $979.8K

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Florence County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Florence fall within the 10 to 20 acres range.

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