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    Cherokee County, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    90 results
    Downtown Historic District Mixed-Use Property
    $199,900
    8,400 SF

    Downtown Historic District Mixed-Use Property

    314,316, N Limestone Street, Gaffney, SC 29340

    Two-story, mixed-use property in Gaffney's historic district.

    • Prime downtown location in Historical District
    • Large 8400 sq. ft. building with multi‑unit potential (4 units)
    • Excellent location for small business or conversion to apartments/hotel
    • Corner lot with adjacent paved city parking
    • Multiple entrances: Downtown main street parking spaces plus private lot with 3 separate back entrances
    Updated: Apr 10
    View details
    Gaffney Multi-Use High-Visibility Property
    $165,900
    0.33 Acres

    Gaffney Multi-Use High-Visibility Property

    403 S Logan Street, Gaffney, SC 29341

    Functional layout suitable for various professional uses or residential conversion.

    • High‑visibility location in the heart of Gaffney with quick access to I‑85 and Hwy 29.
    • Functional, flexible interior layout suitable for a variety of professional uses.
    • Six private offices, two restrooms, and a welcoming lobby.
    • Convenient front and rear parking with potential for expansion.
    • Ramp with railing for easy accessibility.
    Updated: Apr 15
    View details
    Prime Commercial Land I-85 Frontage
    $630,000
    6.06 Acres

    Prime Commercial Land I-85 Frontage

    Commercial land with high visibility and access off I-85.

    0 Macedonia Road, Gaffney, SC 29341
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    Gaffney Commercial Site I-85 Frontage
    $830,000
    8.43 Acres

    Gaffney Commercial Site I-85 Frontage

    Prime commercial land off I-85, high visibility and access.

    0 Macedonia Road, Gaffney, SC 29341
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    Gaffney Commercial Site For Sale
    $279,000
    1.89 Acres

    Gaffney Commercial Site For Sale

    Prime commercial location near Floyd Baker Blvd and I-85.

    530,526,524 W Frederick Street, Gaffney, SC 29341
    View details
    Blacksburg Vacant Land Near I-85
    $364,200
    12.14 Acres

    Blacksburg Vacant Land Near I-85

    Commercial land with high visibility and accessibility near I-85.

    118 Phelps Road, Blacksburg, SC 29702
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    Commercial Building in Gaffney, SC
    $347,000
    0.40 Acres

    Commercial Building in Gaffney, SC

    Rezoned commercial property suitable for various business ventures.

    111 W Rutledge Avenue, Gaffney, SC 29340
    View details
    Downtown Historical District Commercial Property
    $199,900
    8,400 SF

    Downtown Historical District Commercial Property

    Two-story brick building with retail and residential potential.

    314,316 N Limestone Street, Gaffney, SC 29340
    View details
    Gaffney Commercial Site Opportunity
    $4,000,000
    11.00 Acres

    Gaffney Commercial Site Opportunity

    Prime 11-acre commercial site in Gaffney, South Carolina.

    0 W Buford Street, Gaffney, SC 29341
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    Prime Commercial Land Opportunity
    $8,000,000
    22.00 Acres

    Prime Commercial Land Opportunity

    22-acre commercial site in established retail corridor.

    0 W Floyd Baker Boulevard, Gaffney, SC 29341
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    Gaffney Commercial Site For Sale
    $575,000
    0.91 Acres

    Gaffney Commercial Site For Sale

    Prime commercial opportunity with major road frontage in Gaffney, SC.

    1207 S Granard Street, Gaffney, SC 29341
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    Gaffney Commercial Land I-85 Visibility
    $830,000
    8.43 Acres

    Gaffney Commercial Land I-85 Visibility

    Prime commercial land with high visibility off I-85 in Gaffney.

    Lot 1 Macedonia Road, Gaffney, SC 29341
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    Gaffney Commercial Land Opportunity
    $630,000
    6.06 Acres

    Gaffney Commercial Land Opportunity

    Prime commercial land with high visibility and development potential.

    Lots 2A & 2B Macedonia Road, Gaffney, SC 29341
    View details
    Gaffney Commercial Land I-85 Exit
    $1,640,000
    15.42 Acres

    Gaffney Commercial Land I-85 Exit

    15.42 acres of commercial land off I-85.

    134 Macedonia Road, Gaffney, SC 29341
    View details
    Waterfront Land on Broad River
    $485,000
    26.11 Acres

    Waterfront Land on Broad River

    26-acre waterfront property with pasture and elevated home site.

    151 Cobb Road, Blacksburg, SC 29702
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    Gaffney Commercial Land Opportunity
    $180,000
    0.93 Acres

    Gaffney Commercial Land Opportunity

    Commercial land available off Interstate 85 in Gaffney, South Carolina.

    Lot 3 Macedonia Road, Gaffney, SC 29341
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    Gaffney Commercial Land Opportunity
    $180,000
    0.93 Acres

    Gaffney Commercial Land Opportunity

    Commercial land for sale off I-85 in Gaffney, SC.

    0 Macedonia Road, Gaffney, SC 29341
    View details
    7.72 Acres in Blacksburg, SC
    $125,000
    7.72 Acres

    7.72 Acres in Blacksburg, SC

    7.72-acre parcel perfect for agricultural use or homestead.

    0 Helms Road, Blacksburg, SC 29702
    View details
    Gaffney Commercial Site I-85 Exit
    $1,640,000
    15.42 Acres

    Gaffney Commercial Site I-85 Exit

    Prime commercial land off I-85 with high visibility and access.

    134 Macedonia Road, Gaffney, SC 29341
    View details
    Cannon Secure Storage For Sale
    $780,000
    11,600 SF

    Cannon Secure Storage For Sale

    Self-storage facility with 75 units near Interstate 85.

    939 N Logan St, Gaffney, SC 29341
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    Gaffney Storage Facility For Sale
    $780,000
    11,600 SF

    Gaffney Storage Facility For Sale

    11,600 SF storage facility with 75 units near I-85.

    939 N Logan St, Gaffney, SC 29341
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    77 Acres Prime For Development
    $1,399,000
    77.30 Acres

    77 Acres Prime For Development

    77 acres in Gaffney, SC, suitable for development.

    00 Victory Trail Road, Gaffney, SC 29340
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    Blacksburg Land Near I-85
    $950,000
    16.87 Acres

    Blacksburg Land Near I-85

    16+ acres of wooded land near I-85.

    137 Crawford Road Road, Blacksburg, SC 29702
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    Gaffney Industrial Facility For Sale
    $1,900,000
    29,400 SF

    Gaffney Industrial Facility For Sale

    29,400 SF industrial facility with warehouse and office space.

    349 Huntington Rd, Gaffney, SC 29341
    View details

    Cherokee County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 90 commercial real estate for sale in Cherokee County, SC, showcased through 90 active listings on our real estate platform. These investment opportunities span a total of 27,212,207 square feet of properties for sale, with an estimated market value of $41,476,500.

    Sale prices for business properties in Cherokee County, SC start at $49,900, averaging $901,663, and reaching up to $8,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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