Florence, SC Commercial Real Estate for Sale

List

Map

Timmonsville, SC Effingham, SC Darlington, SC Coward, SC Marion, SC Latta, SC Pamplico, SC Lamar, SC

98 properties

Sort:

Updated: May 20

Occupied Neighborhood Retail Center

823-817 S Cashua Drive, Florence, SC 29501

$1,550,000

15,450 sqft

Fully occupied retail center across the street from Walmart Neighborhood Market
Two connected buildings: 817 S. Cashua (7,450 SF) and 823 S. Cashua (8,000 SF)
Both buildings reported in good condition
Cooling provided via heat pump

View details

This listing looks promising.

Here's a quick look at some key insights for

823-817 S Cashua Drive, Florence, SC 29501

View Property Analytics

Est. Cap Rate

7.1%
Above avg (5.9%)
Est. NOI

$111K
Annual
Price @ 7% Cap

$1.58M
Above asking

View Property Analytics

Updated: Jul 10

Medical Office Building with Parking

1706 2nd Loop Rd., Florence, SC 29501

$1,650,000

8,291 sqft 1.34 AC lot

8,300 sq ft commercial facility on 1.34 acres with CI zoning
Former cardiology practice with 13 exam rooms plus X‑ray room
Includes reception lobby, executive and administrative offices, and board room
Extensive storage including a fully floored attic
Covered patient drop‑off, four‑bay carport, and 62 parking spaces

View details

Historic Downtown Office Building

248-260 W Evans st., Florence, SC 29501

$2,700,000

16,304 sqft 1.47 AC lot

Historic office building with multiple suites and ample on-site parking in downtown Florence.

View details

Mobile Heavy Truck Repair Business

N Cashua Dr., Florence, SC 29501

$580,000

1,000 sqft 2.00 AC lot

For sale as a business-only turnkey operation for heavy truck and mobile repair services.

View details

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Freestanding Retail Showroom and Warehouse

2803 West Palmetto Street, Florence, SC 29501

$799,000

15,541 sqft 0.86 AC lot

Freestanding retail property combines showroom and warehouse space on a hard-corner site with approximately 174 feet of frontage.

View details

Office Property with Parking

2228 W Palmetto St., Florence, SC 29501

$250,000

1,405 sqft 0.31 AC lot

Office space on a 0.31-acre lot with parking and strong visibility along W Palmetto St in Florence.

View details

Remodeled Medical Office Building

910 W Evans st, Florence, SC 29501

$300,000

2,165 sqft 0.27 AC lot

Turnkey, fully rebuilt office suite with treatment-room style spaces, new HVAC, and updated plumbing and electrical.

View details

Vacant Farm-Zoned Development Land

1714 2nd Loop Rd., Florence, SC 29501

$1,650,000

4.03 AC lot

4.03-acre vacant parcel zoned Farm Vacant (FV) with access to 2nd Loop Road in Florence, SC.

View details

Historic Downtown Office Building

260 W Evans St, Florence, SC 29501

$2,700,000

16,000 sqft 1.47 AC lot

A 16,000-square-foot historic office building with multiple suites, including a law firm and other tenants, plus over 100 parking spaces.

View details

Vacant Specialty Commercial Building

818 S Cashua Drive, Florence, SC 29501

$265,000

2,422 sqft 0.37 AC lot

Vacant specialty building sold as-is, with access via a Sentri lockbox at the back door near a small patio.

View details

Commercial Office Property with Parking

2228 W Palmetto St., Florence, SC 29501

$250,000

1,405 sqft

Office-focused commercial property along a high-traffic corridor, offering visibility, accessibility, and ample on-site parking.

View details

Day Care Center For Sale

822 S Cashua, Florence, SC 29501

$285,000

2,067 sqft 0.60 AC lot

Existing day care center offered as-is with special showing requirements and lockbox access on the back door.

View details

Buildable Retail Development Land

3312 Meadors Road, Florence, SC 29501

$1,500,000

7.27 AC lot

Level, buildable two-parcel land package suited for a range of retail and service-oriented development uses.

View details

Vacant Commercial/Industrial Specialty Property

818 S Cashua Drive, Florence, SC 29501

$265,000

2,422 sqft

Vacant as-is commercial/industrial specialty property with a back-door patio access and Sentri lockbox for convenient showing.

View details

Development-Ready Commercial Land Site

917 S Cashua Drive, Florence, SC 29501

$980,000

4.76 AC lot

4.76-acre B3-zoned parcel on a four-lane corridor with SCDOT-reported traffic near major daily-use anchors.

View details

Cleared Level Commercial Land Lot

207 S Irby St., Florence, SC 29501

$750,000

0.52 AC lot

Level, cleared commercial lot with utilities available in Florence, SC.

View details

Freestanding Office Building For Sale

1221 West Evans Street, Florence, SC 29501

$175,000

1,085 sqft

Leased office building with immediate income potential in Florence.

View details

Commercial Land Opportunity

W Leggs Cir, Florence, SC 29501

$129,900

4.00 AC lot

4-acre commercial land in Florence County, positioned in a high-traffic area for a wide range of business uses.

View details

Special Purpose

822 S Cashua, Florence, SC 29501

$285,000

2,067 sqft

Day care centers · 2,067 SF

View details

B-6 Zoned Commercial Land Opportunity

720 S Barringer Street, Florence, SC 29506

$47,900

840 sqft 0.17 AC lot

B-6 zoned parcel suited for a range of commercial development options.

View details

Florence Commercial Development Opportunity

2621 West Palmetto Street, Florence, SC 29501

$1,200,000

4.54 AC lot

4.54 acre commercial parcel on high-traffic corridor.

View details

Flat Corner Commercial Land

635 N Coit St., Florence, SC 29501

$275,000

0.91 AC lot

Commercially zoned flat, buildable corner lot with utilities available.

View details

Former Convenience Store Investment Property

1134 E Howe Springs Road, Florence, SC 29505

$125,000

2,400 sqft

Fixer-upper retail property with 150' frontage, great investment potential.

View details

Florence Commercial Land For Sale

Presbyterian Road, Florence, SC 29501

$792,792

1.82 AC lot

1.82 acre commercial land near I-95 in Florence, SC.

View details

Florence, SC Commercial Real Estate Market Trends and Statistics

Explore 98 commercial real estate for sale in Florence, SC, showcased through 98 active listings on our real estate platform. These investment opportunities span a total of 797,920 square feet of properties for sale, with an estimated market value of $59,480,620.

Sale prices for business properties in Florence, SC start at $47,900, averaging $1,565,279, and reaching up to $16,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

List

Map

Demographics Overview

Population 92K

Population Growth (5Y) -1.5%

Median Household Income $61,793

College Educated 17.4%

High-Yield Neighborhoods for Investment

Identify Florence submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
Darlington	$525K
Florence	$802K

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Florence County

New Delisted

Total CRE Inventory on Market (SF)

Need Help?

Reach out if you need assistance with Realmo tools or have questions about your listings