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    Florence, SC Commercial Real Estate for Sale

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    Greenville, SC Aiken, SC Beaufort, SC
    112 results
    Remodeled Commercial Building Near Downtown
    $340,000
    2,165 SF

    Remodeled Commercial Building Near Downtown

    910 W Evans st, Florence, SC 29501

    Turnkey commercial property in prime location with excellent visibility.

    • Completely remodeled/rebuilt from the ground up with new roof, HVAC, electrical, and plumbing.
    • Prime location minutes from downtown Florence with excellent visibility and access.
    • Turnkey property suitable for a medical office, salon, law firm, or small business.
    • Five spacious rooms that can serve as private offices or treatment spaces.
    • Modern kitchen with brand‑new cabinets and granite countertops.
    Updated: Apr 1
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    Historic Downtown Florence Commercial Building
    $2,700,000
    16,304 SF

    Historic Downtown Florence Commercial Building

    248-260 W Evans st., Florence, SC 29501

    16,000 SF historic building in thriving downtown Florence.

    • Prime downtown Florence location in a thriving area.
    • Large 16,000 sq ft historic building with limitless potential.
    • Significant parking available (over 100 spaces), rare for downtown.
    • Versatile space currently configured with multiple tenants (Law Firm, H&R Block, Hair Studio).
    • Spacious 1.47‑acre lot allows for growth and development.
    Updated: Mar 9
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    Industrial Building in Florence, SC
    $550,000
    67,518 SF

    Industrial Building in Florence, SC

    Standalone industrial building suitable for various commercial and industrial uses.

    121 Lawson St, Florence, SC 29501
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    Established Auto Body Business For Sale
    $1,305,000
    4,125 SF

    Established Auto Body Business For Sale

    Turn-key auto body business with equipment, client roster, and real estate.

    803 Ranch Rd., Florence, SC 29506
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    Industrial Buildings with Power & Access
    $199,000
    40,000 SF

    Industrial Buildings with Power & Access

    Two industrial buildings ideal for fabrication, automotive, or storage.

    120 N Guerry Street, Florence, SC 29501
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    Prime Commercial Development Site
    $980,000
    4.76 Acres

    Prime Commercial Development Site

    4.76-acre commercial land with high traffic exposure in Florence, SC.

    917 S Cashua Drive, Florence, SC 29501
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    Prime Commercial Land Near I-95
    $1,500,000
    7.27 Acres

    Prime Commercial Land Near I-95

    7.27 acres of commercial land near I-95 in Florence, SC.

    3312 Meadors Road, Florence, SC 29501
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    Prime Location Commercial Land
    $265,000
    2,422 SF

    Prime Location Commercial Land

    Commercial land in a prime location, sold as is.

    818 S Cashua Drive, Florence, SC 29501
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    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
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    Commercial Property Near Walmart Market
    $285,000
    2,067 SF

    Commercial Property Near Walmart Market

    Commercial property for sale next to Walmart market in Florence.

    822 S Cashua, Florence, SC 29501
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    Land Near Walmart Market
    $90,000
    0.22 Acres

    Land Near Walmart Market

    Commercial land for sale next to Walmart Market.

    2416 W Delmae Dr, Florence, SC 29501
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    Prime Commercial Land Opportunity
    $129,900
    4.00 Acres

    Prime Commercial Land Opportunity

    4-acre commercial land in high-traffic Florence County.

    TBD W Leggs Cir, Florence, SC 29501
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    Florence Commercial Land For Sale
    $49,900
    840 SF

    Florence Commercial Land For Sale

    B-6 zoned property with commercial and redevelopment options.

    720 S Barringer, Florence, SC 29506
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    Florence Commercial Land For Sale
    $396,396
    0.91 Acres

    Florence Commercial Land For Sale

    0.91 acre commercial land parcel in Florence, South Carolina.

    Presbyterian Road, Florence, SC 29501
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    Florence Commercial Land For Sale
    $792,792
    1.82 Acres

    Florence Commercial Land For Sale

    1.82 acre commercial land near I-95 in Florence, SC.

    TBD Presbyterian Road, Florence, SC 29501
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    Turnkey Fish Market Opportunity
    $250,900
    2,499 SF

    Turnkey Fish Market Opportunity

    Profitable, equipped fish market for sale in Florence, SC.

    1401 W Darlington Street, Florence, SC 29501
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    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    1714 Second Loop Rd., Florence, SC 29501
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    Mixed-Use Property in Great Location
    $429,000
    3,764 SF

    Mixed-Use Property in Great Location

    Mixed-use property, previously commercial, next to medical staffing business.

    605 S Dargan St, Florence, SC 29506
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    Corner Lot in Florence, SC
    $125,000
    0.10 Acres

    Corner Lot in Florence, SC

    Commercial corner lot available in Florence, South Carolina.

    360 N Dargan St, Florence, SC 29501
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    Unzoned Acreage in Florence, SC
    $255,000
    6.54 Acres

    Unzoned Acreage in Florence, SC

    6.54 acres of unzoned land with potential uses.

    6.54 Acres-TBD Alligator Rd., Florence, SC 29501
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    Florence Office Building For Sale
    $1,500,000
    7,517 SF

    Florence Office Building For Sale

    Office building with 7,517 square feet of space in Florence.

    1706 Second Loop Rd., Florence, SC 29501
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    Florence Commercial Land For Sale
    $278,784
    0.64 Acres

    Florence Commercial Land For Sale

    0.64 acre commercial land parcel in Florence, South Carolina.

    Presbyterian Road, Florence, SC 29501
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    Commercial Property on Pamplico Highway
    $395,000
    0.90 Acres

    Commercial Property on Pamplico Highway

    Approximately 1.2 acre commercial property for sale or lease.

    111 Pamplico Highway, Florence, SC 29501
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    Commercial Land Near Post Office
    $795,000
    3.50 Acres

    Commercial Land Near Post Office

    Commercial land with utilities available, near Truist Bank.

    118 N Cashua Drive, Florence, SC 29501
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    Florence, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 112 commercial real estate for sale in Florence, SC, showcased through 112 active listings on our real estate platform. These investment opportunities span a total of 1,892,246 square feet of properties for sale, with an estimated market value of $21,194,772.

    Sale prices for business properties in Florence, SC start at $31,000, averaging $847,790, and reaching up to $4,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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