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    Lancaster County, SC Commercial Real Estate for Sale

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    113 properties
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    Updated Retail Storefront
    Updated: Sep 16
    Updated Retail Storefront

    135 E Marion Street, Kershaw, SC 29067

    $155,000
    0.05 AC lot
    New roof, windows, electrical, HVAC, plumbing, and water heater
    0.05‑acre commercial site within Kershaw city limits
    KER zoning
    Central heating and central air
    Public sewer service
    View details
    Commercial Land with Highway Frontage
    Updated: May 28
    Commercial Land with Highway Frontage

    2383 Charlotte Highway, Lancaster, SC 29720

    $2,200,000
    15.55 AC lot
    15.55 acres of commercial land across two parcels: 8.88 acres and 6.67 acres
    463' of road frontage along Charlotte Highway/Hwy 521
    G‑B zoning, identified as General Business
    Stated daily traffic count of 27,500
    Borders Lancaster Medical Park
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    Commercial Land with Office Building
    Commercial Land with Office Building

    731 S Market Street, Lancaster, SC 29720

    $140,000
    1.62 AC lot

    B3-zoned commercial parcel with an existing office building and public water and sewer on site.

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    NNN Automotive Property
    NNN Automotive Property

    1878 Great Falls Hwy, Lancaster, SC 29720

    $1,400,000
    7,000 sqft

    Net-leased automotive retail property with a corporate guarantee and more than seven years remaining on the lease.

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    Medical Office Building
    Medical Office Building

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1.76 AC lot

    Electric heating and air conditioning serve this office property within Kershaw’s town limits.

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    Vacant Storefront Building
    Vacant Storefront Building

    401 E Gay Street, Lancaster, SC 29720

    $134,999
    0.12 AC lot

    Existing parking and a flexible commercial building support a range of potential business uses.

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    Highway-Adjacent Commercial Land
    Highway-Adjacent Commercial Land

    6993 Charlotte Highway, Lancaster, SC 29707

    $2,500,000
    3.96 AC lot

    The tract carries LDR zoning and includes an older residence plus a nonhabitable mobile home.

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    Flex Space with Acreage
    Flex Space with Acreage

    9 Sawmill Rd, Kershaw, SC 29067

    $569,000
    8,088 sqft

    Mostly cleared acreage surrounds a substantial commercial building that requires renovation.

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    Versatile Land on Charlotte Highway
    Versatile Land on Charlotte Highway

    Charlotte Highway, Lancaster, SC 29707

    $1,500,000
    5.61 AC lot

    5.61-acre wooded property with residential and commercial potential.

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    Self-Storage Garage Community
    Self-Storage Garage Community

    8461 Possum Hollow Road, Indian Land, SC 29707

    $248,000
    0.10 AC lot

    Gated entry provides around-the-clock access to garage spaces serving vehicle storage and other owner uses.

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    Updated Storefront Property
    Updated Storefront Property

    135 E Marion Street, Kershaw, SC 29067

    $155,000
    1,200 sqft

    Recent improvements include a new roof, windows, electrical system, HVAC, plumbing, and water heater.

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    Fenced Agricultural Land with Improvements
    Fenced Agricultural Land with Improvements

    3764 Old Georgetown Road W, Kershaw, SC 29067

    $170,000
    20.00 AC lot

    Pastured acreage includes a mobile home, garden area, fencing, and multiple storage buildings.

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    Self-Storage Garage with Half Bath
    Self-Storage Garage with Half Bath

    8461 Possum Hollow Road, Indian Land, SC 29707

    $183,000
    0.10 AC lot

    Epoxy flooring and a private restroom support vehicle storage or other garage use.

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    Two-Building Storefront Property
    Two-Building Storefront Property

    1313, 1317 Hwy 9 Bypass W, Lancaster, SC 29720

    $499,000
    2,175 sqft

    Commercial property with existing retail occupancy and dry-cleaning equipment included.

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    Self-Storage Garage Community
    Self-Storage Garage Community

    8461 Possum Hollow Road, Indian Land, SC 29707

    $301,400
    0.10 AC lot

    Gated access, broad drive lanes, and garage configurations accommodate vehicle storage and other owner uses.

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    Creek-Bordered Hunting Land
    Creek-Bordered Hunting Land

    3390 Hunter Road lot: 1, Kershaw, SC 29067

    $599,000
    112.00 AC lot

    Managed pine stands, hardwood bottoms, and an elevated clearing shape this multi-use recreational tract.

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    Gated Storage Garage Unit
    Gated Storage Garage Unit

    8461 Possum Hollow Road M100, Indian Land, SC 29707

    $248,000
    552 sqft

    Secure 24/7 gated access storage garage unit with large roll-up door openings and optional mezzanine.

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    Commercial Land Near Proposed Intersection
    Commercial Land Near Proposed Intersection

    Charlotte Hwy lot: 2, Lancaster, SC 29720

    $2,500,000
    18.00 AC lot

    Eighteen-acre tract with proposed commercial rezoning and public sewer identified near Charlotte Highway.

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    Commercial Building with Fenced Parking
    Commercial Building with Fenced Parking

    305 E Arch St Unit 36, Lancaster, SC 29720

    $250,000
    1,653 sqft

    Commercial building with open area, offices, and parking.

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    General Business Commercial Land
    General Business Commercial Land

    2383 Charlotte Highway, Lancaster, SC 29720

    $2,200,000
    15.55 AC lot

    General Business-zoned land with substantial highway frontage and proximity to Lancaster Medical Park.

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    Gated 24/7 Garage Storage Facility
    Gated 24/7 Garage Storage Facility

    L104-8461 Possum Hollow Rd, Indian Land, SC 29707

    $301,400
    3,000 sqft

    Secure, gated garage-style storage offers wide drive lanes, large roll-up doors, and optional mezzanines.

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    Fenced Agricultural Land
    Fenced Agricultural Land

    1049 Culp Ferguson Road, Lancaster, SC 29720

    $2,775,000
    84.67 AC lot

    Fenced farmland features open fields, pastures, wooded buffers, rolling terrain, and a pond.

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    Historic Downtown Storefront
    Historic Downtown Storefront

    136 N. Hampton Street, Kershaw, SC 29067

    Contact for pricing
    6,648 sqft

    Retail property positioned within Kershaw’s traditional South Carolina downtown district.

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    Farmland Tract with Road Frontage
    Farmland Tract with Road Frontage

    6327 Witherspoon Trail, Lancaster, SC 29720

    $625,000
    19.32 AC lot

    Zoned RN farmland tract with county water available and septic needed, plus natural water features along the property.

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    Lancaster County, SC Commercial Real Estate Market Trends and Statistics

    Explore 113 commercial real estate for sale in Lancaster County, SC, showcased through 113 active listings on our real estate platform. These investment opportunities span a total of 263,643 square feet of properties for sale, with an estimated market value of $66,461,853.

    Sale prices for business properties in Lancaster County, SC start at $65,000, averaging $910,436, and reaching up to $10,855,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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