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    Lancaster County, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    98 results
    Commercial Building on 0.66 Acres
    $175,000
    1,936 SF

    Commercial Building on 0.66 Acres

    7162 Flat Rock Rd., Kershaw, SC 29067

    Commercial building with parking and picnic area on 0.66 acres.

    • Commercial building suitable for store use
    • Large .66 acre lot
    • Ample parking space
    • Brick construction
    • Central heating and air conditioning
    Updated: Mar 24
    View details
    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    1201 Colonial Commons Court, Lancaster, SC 29720

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    • Prime location minutes from MUSC (Medical University of South Carolina).
    • Two professional office buildings on one property.
    • Zoned "PO" Professional Office by the City of Lancaster.
    • Building 1 features a medical office layout with 14 rooms and a wired X‑ray room.
    • New flooring and new roof installed in Building 1.
    Updated: Dec 1, 2025
    View details
    Versatile Land on Charlotte Highway
    $1,500,000
    5.61 Acres

    Versatile Land on Charlotte Highway

    5.61-acre wooded property with residential and commercial potential.

    Charlotte Highway, Lancaster, SC 29707
    View details
    Prime Land on Highway 521
    $2,500,000
    3.96 Acres

    Prime Land on Highway 521

    3.96 acres ideal for commercial or residential development.

    6993 Charlotte Highway, Lancaster, SC 29707
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    Kershaw County 10-Acre Timberland
    $77,500
    10.00 Acres

    Kershaw County 10-Acre Timberland

    10 acres of mixed timberland, ideal for homesteading.

    931 Charlie Johnson Road, Kershaw, SC 29067
    View details
    19.32 Acres in Indian Land
    $625,000
    19.32 Acres

    19.32 Acres in Indian Land

    Land with natural features ideal for country living.

    6327 Witherspoon Trail, Lancaster, SC 29720
    View details
    Kershaw County Timberland Homestead
    $108,500
    15.50 Acres

    Kershaw County Timberland Homestead

    15.5 acres of mixed timberland, ideal for homesteading.

    931 Charlie Johnson Road, Kershaw, SC 29067
    View details
    Kershaw County Timberland Homestead
    $77,500
    10.00 Acres

    Kershaw County Timberland Homestead

    10 acres of mixed timberland, ideal for homestead or recreation.

    931 Charlie Johnson Road, Kershaw, SC 29067
    View details
    Kershaw County Timberland Opportunity
    $105,500
    14.75 Acres

    Kershaw County Timberland Opportunity

    14.75 acres of mixed timberland, ideal for homesteading.

    931 Charlie Johnson Road, Kershaw, SC 29067
    View details
    Kershaw County Timberland Homestead
    $77,500
    10.00 Acres

    Kershaw County Timberland Homestead

    10 acres of mixed timberland, ideal for homesteading.

    931 Charlie Johnson Road, Kershaw, SC 29067
    View details
    Commercially Zoned Land Opportunity
    $150,000
    4.80 Acres

    Commercially Zoned Land Opportunity

    5-acre commercially zoned land in a growing residential area.

    169 Rowland Avenue, Heath Springs, SC 29058
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    Lancaster Land with Highway Frontage
    $1,600,000
    25.00 Acres

    Lancaster Land with Highway Frontage

    25 acres of land ideal for development or investment.

    3080 Charlotte Highway, Lancaster, SC 29720
    View details
    Commercial Land in Lancaster, SC
    $75,000
    0.28 Acres

    Commercial Land in Lancaster, SC

    Prime commercial location with high visibility and easy access.

    E Arch Street, Lancaster, SC 29720
    View details
    Land For Sale, Lancaster SC
    $75,000
    0.47 Acres

    Land For Sale, Lancaster SC

    Commercial land available in Lancaster, South Carolina.

    10129 Lakeshore Drive, Lancaster, SC 29720
    View details
    Lancaster, SC Land For Sale
    $55,000
    0.57 Acres

    Lancaster, SC Land For Sale

    Commercial land available in Lancaster, South Carolina.

    Airport Road, Lancaster, SC 29720
    View details
    Indian Land Oasis: Rural Retreat
    $1,395,000
    22.54 Acres

    Indian Land Oasis: Rural Retreat

    22+ acre estate with custom home, pool, and outdoor recreation.

    1115 John Short Road, Indian Land, SC 29707
    View details
    Lancaster Commercial Land For Sale
    $2,500,000
    18.00 Acres

    Lancaster Commercial Land For Sale

    Commercial land with development potential in Lancaster, South Carolina.

    Charlotte Hwy lot: 2, Lancaster, SC 29720
    View details
    Lancaster County Acreage with Development Potential
    $2,775,000
    84.67 Acres

    Lancaster County Acreage with Development Potential

    84.67 acres in Lancaster County ideal for various uses.

    1049 Culp Ferguson Road, Lancaster, SC 29720
    View details
    Prime Development Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Development Land on Charlotte Highway

    15.55 acres with high traffic, development potential.

    2383 Charlotte Highway, Lancaster, SC 29720
    View details
    Prime Development Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Development Land on Charlotte Highway

    Development opportunity on a high-traffic corridor near residential developments.

    2383 Charlotte Highway, Lancaster, SC 29720
    View details
    Protected Timberland Tract in Lancaster
    $1,332,500
    533.00 Acres

    Protected Timberland Tract in Lancaster

    533-acre recreational timberland tract near Lancaster, South Carolina.

    Duckwood Rd., Lancaster, SC 29720
    View details
    Kershaw Acreage with Development Potential
    $925,000
    186.90 Acres

    Kershaw Acreage with Development Potential

    186.9 acres of land with development and agricultural possibilities.

    703 Neds Creek Road, Kershaw, SC 29067
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    Versatile Commercial Building in Lancaster
    $349,000

    Versatile Commercial Building in Lancaster

    Two-story commercial building with offices in downtown Lancaster, SC.

    302 N White St, Lancaster, SC 29720
    View details
    Scenic Land Parcel in Indian Land
    $615,000
    4.66 Acres

    Scenic Land Parcel in Indian Land

    4.66-acre parcel perfect for estate home or equestrian haven.

    000 Jim Wilson Road, Indian Land, SC 29707
    View details

    Lancaster County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 98 commercial real estate for sale in Lancaster County, SC, showcased through 98 active listings on our real estate platform. These investment opportunities span a total of 59,768,022 square feet of properties for sale, with an estimated market value of $32,537,200.

    Sale prices for business properties in Lancaster County, SC start at $55,000, averaging $813,430, and reaching up to $2,775,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Commercial real estate for Sale Near Lancaster, SC

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