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    Lancaster County, SC Commercial Real Estate for Sale

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    Kershaw Office Building on Large Lot
    Updated: May 4
    Kershaw Office Building on Large Lot

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1,100 sqft 1.76 AC lot
    Large 1.76 acre lot (2 lot parcel) within town limits
    Potential for rezoning to residential and remodeling into a home
    Existing 1100+ sq ft building suitable for office use
    Located in a doctor care area
    'Easy walking' within city limits
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    Retail Storefront with Parking
    Updated: Mar 24
    Retail Storefront with Parking

    7162 Flat Rock Rd., Kershaw, SC 29067

    $175,000
    1,936 sqft 0.66 AC lot
    .66‑acre commercial building used for a store
    Central air cooling
    Plenty of on‑site parking
    Picnic area on the property
    Includes TV with surround sound
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    Prime Development Land Lancaster, SC
    Prime Development Land Lancaster, SC

    2383 Charlotte Highway, Lancaster, SC 29720

    $2,200,000
    15.55 AC lot

    Development opportunity on a growing corridor near residential communities.

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    Kershaw Estate: Southern Luxury Venue
    Kershaw Estate: Southern Luxury Venue

    393 Youngs Bend Road, Kershaw, SC 29067

    $1,975,000
    10,000 sqft 10.00 AC lot

    10,000+ sq ft estate on 10 acres near Camden.

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    Adjacent Single-Family Rental Portfolio
    Adjacent Single-Family Rental Portfolio

    209 Rickenbacker Street, Lancaster, SC 29720

    $985,000
    0.88 AC lot

    Eight adjacent 2BR/1BA rentals with a storage warehouse and included vacant lot, currently fully occupied.

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    Versatile Land on Charlotte Highway
    Versatile Land on Charlotte Highway

    Charlotte Highway, Lancaster, SC 29707

    $1,500,000
    5.61 AC lot

    5.61-acre wooded property with residential and commercial potential.

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    Prime Land on Highway 521
    Prime Land on Highway 521

    6993 Charlotte Highway, Lancaster, SC 29707

    $2,500,000
    3.96 AC lot

    3.96 acres ideal for commercial or residential development.

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    Historic Mixed-Use Retail/Office Buildings
    Historic Mixed-Use Retail/Office Buildings

    209-227 S. Main Street, Lancaster, SC 29720

    $575,000
    29,151 sqft

    Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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    Lancaster Commercial Building For Sale
    Lancaster Commercial Building For Sale

    401 E Gay Street, Lancaster, SC 29720

    $139,999
    0.12 AC lot

    Commercial building in growing area with business or investment potential.

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    Kershaw, SC Single-Family Property
    Kershaw, SC Single-Family Property

    167 Shop Road, Kershaw, SC 29067

    $1,200,000
    1.80 AC lot

    Single-family property for sale in Kershaw, South Carolina.

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    Downtown Mixed-Use Redevelopment Property
    Downtown Mixed-Use Redevelopment Property

    210 S. White Street, Lancaster, SC 29720

    $760,000
    22,251 sqft

    Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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    Lancaster Land with Highway Frontage
    Lancaster Land with Highway Frontage

    3080 Charlotte Highway, Lancaster, SC 29720

    $1,600,000
    25.00 AC lot

    25 acres of land ideal for development or investment.

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    Lancaster Commercial Land For Sale
    Lancaster Commercial Land For Sale

    Charlotte Hwy lot: 2, Lancaster, SC 29720

    $2,500,000
    18.00 AC lot

    Commercial land with development potential in Lancaster, South Carolina.

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    1930s Retail/Office Building Portfolio
    1930s Retail/Office Building Portfolio

    116 Arch Street, Lancaster, SC 29720

    $575,000
    29,444 sqft

    Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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    19.32 Acres in Indian Land
    19.32 Acres in Indian Land

    6327 Witherspoon Trail, Lancaster, SC 29720

    $625,000
    19.32 AC lot

    Land with natural features ideal for country living.

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    Lancaster County Acreage with Development Potential
    Lancaster County Acreage with Development Potential

    1049 Culp Ferguson Road, Lancaster, SC 29720

    $2,775,000
    84.67 AC lot

    84.67 acres in Lancaster County ideal for various uses.

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    Waterfront Wedding Event Venue Property
    Waterfront Wedding Event Venue Property

    4223 Cedar Creek Rd, Lancaster, SC 29720

    $2,400,000
    5,000 sqft

    Boutique event venue on a bluff overlooking the Catawba River with purpose-built indoor space and outdoor gathering areas.

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    Kershaw Acreage Homestead Opportunity
    Kershaw Acreage Homestead Opportunity

    931 Charlie Johnson Road, Kershaw, SC 29067

    $120,000
    17.50 AC lot

    17.5 acre homestead in Kershaw County's Sandhills corridor.

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    Downtown Mixed-Use Building for Renovation
    Downtown Mixed-Use Building for Renovation

    229 S. Main Street, Lancaster, SC 29720

    $275,000
    15,266 sqft

    Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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    Wooded Timberland Tract
    Wooded Timberland Tract

    931 Charlie Johnson Road, Kershaw, SC 29067

    $180,000
    24.68 AC lot

    Mixed pine and hardwood wooded acreage with wildlife potential and road access off major routes near Kershaw County.

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    Mixed-Use Investment Opportunity
    Mixed-Use Investment Opportunity

    979-987 University Dr, Lancaster, SC

    $1,150,000
    20,606 sqft 2.15 AC lot

    Multi-tenant property with retail, office, industrial, and storage units.

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    Kershaw County Timberland Homestead
    Kershaw County Timberland Homestead

    931 Charlie Johnson Road, Kershaw, SC 29067

    $105,500
    15.00 AC lot

    15 acres of mixed timberland, ideal for homesteading.

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    Gated 24/7 Garage Storage Facility
    Gated 24/7 Garage Storage Facility

    L104-8461 Possum Hollow Rd, Indian Land, SC 29707

    $301,400
    3,000 sqft

    Secure, gated garage-style storage offers wide drive lanes, large roll-up doors, and optional mezzanines.

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    Rural Land with Creek & Trails
    Rural Land with Creek & Trails

    1115 John Short Road, Indian Land, SC 29707

    $1,295,000
    22.54 AC lot

    Over 22 acres with a custom estate home, fenced yard, and outdoor recreation amenities including equestrian and hunting trails.

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    Lancaster County, SC Commercial Real Estate Market Trends and Statistics

    Explore 91 commercial real estate for sale in Lancaster County, SC, showcased through 91 active listings on our real estate platform. These investment opportunities span a total of 265,683 square feet of properties for sale, with an estimated market value of $31,586,150.

    Sale prices for business properties in Lancaster County, SC start at $150,000, averaging $1,754,786, and reaching up to $11,615,750 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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