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    South Carolina Commercial Real Estate for Lease

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    Greenville, SC Columbia, SC Myrtle Beach, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Conway, SC
    3,040 properties
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    ± .42 Acres - ± 2.57 Acres Immediately Available For Lease
    ± .42 Acres - ± 2.57 Acres Immediately Available For Lease

    296 Lemuels Rd, Gaffney, SC 29341

    $850/Mo

    ± .42 Acres - ± 2.57 Acres Immediately Available For Lease

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    Office Space Available For Rent
    Office Space Available For Rent

    115 Fairchild St, Charleston, SC

    Full service Daniel Island
    Contact for pricing
    8–14 people  5 spaces  2,131 sqft  12.89 acres

    Office space for rent, full service, 2,131 square feet.

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    Retail Space in Galleria Center
    Retail Space in Galleria Center

    9660 N Kings Hwy, Myrtle Beach, SC

    Triple net (NNN)
    Contact for pricing
    3,000 sqft

    Retail opportunity in Kroger-anchored Galleria Shopping Center at Lake Arrowhead.

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    Medical Office Space
    Medical Office Space

    8910 Two Notch Rd, Columbia, SC 29223

    Full service
    Contact for pricing
    28–47 people  1 space  7,072 sqft
    Highway access + Road access

    Professional office space available near major interstates and retail centers in northeast Columbia.

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    Commercial Land in Rock Hill
    Commercial Land in Rock Hill

    1930 Sharonwood Ln, Rock Hill, SC

    Contact for pricing
    1.54 acres

    Commercial development land for lease in Rock Hill, SC.

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    Shopping Center with Signalized Access
    Shopping Center with Signalized Access

    95 Mathews Dr, Hilton Head Island, SC 29926

    Contact for pricing
    52,000 sqft

    Former Sam’s Club retail space in a shopping center with signalized access to William Hilton Pkwy.

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    Commercial Space for Lease
    Commercial Space for Lease

    3112 Devine St, Columbia, SC 29205

    Full service Shandon Neighborhood Council
    Contact for pricing
    5–9 people  1 space  1,368 sqft

    Commercial space available for lease.

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    Office Sublease Space
    Office Sublease Space

    400 Northeast Dr, Columbia, SC 29203

    Triple net (NNN) North Columbia Civic Club (Greenview)
    Contact for pricing
    18–30 people  1 space  4,550 sqft
    Highway access

    Office space available for sublease with ample parking and easy access off I-20.

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    Call Center Office Sublease
    Call Center Office Sublease

    810 Dutch Square Blvd, Columbia, SC 29210

    Full service
    Contact for pricing
    31–51 people  1 space  7,755 sqft

    Sublease office space built out as a call center with training, conference, kitchen, and nine individual offices.

    Training room  Conference room  Kitchen  Dining area
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    Class A Office High-Rise Suites
    Class A Office High-Rise Suites

    1441 Main St, Columbia, SC 29201

    Class A Downtown Neighborhood Association
    Contact for pricing
    24–40 people  6,069 sqft  Multi-tenant

    Class A office high-rise with a range of suite sizes and on-site amenities including conference space and attended visitor parking.

    Fitness center  Conference suite with WiFi, presentation equipment and kitchen  Climate controlled on-site storage  Full service banking and ATM
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    Commercial Land Outparcel
    Commercial Land Outparcel

    285 Applewood Center Pl, Seneca, SC 29678

    Contact for pricing

    Build-to-suit or ground-lease options are available within a Belk-anchored shopping center.

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    Separately Metered Retail Space
    Separately Metered Retail Space

    4128 Clemson Boulevard, Anderson, SC 29621

    $1,300/Mo
    1,100–2,200 sqft

    The property offers parking and access from Clemson Boulevard.

    Separately metered
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    Standalone Office/Retail Building For Rent
    Standalone Office/Retail Building For Rent

    2101 Gervais St, Columbia, SC

    Historic Waverly Neighborhood Association
    Contact for pricing
    10–17 people  2,650 sqft  0.41 acres

    2,650 SF office/retail building with parking in Columbia, SC.

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    Modern Office Space For Rent
    Modern Office Space For Rent

    2701 Alex Lee Blvd, Florence, SC 29506

    Gross
    Contact for pricing
    28–47 people  7,145 sqft  Built 2009

    7,145 SF customizable office space in Florence, SC.

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    Standalone Office-Retail Building
    Standalone Office-Retail Building

    2101 Gervais St, Columbia, SC 29204

    Historic Waverly Neighborhood Association
    Contact for pricing
    12–20 people  3,006 sqft  0.41 acres
    MU-1

    Standalone office/retail building offers two 1,325 SF floorplates with open workspace and select private offices.

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    Multi-Tenant Retail Suite
    Multi-Tenant Retail Suite

    1632 N Main Street, Anderson, SC 29621

    Triple net (NNN)
    $12 SF/Yr
    Multi-tenant  2,031 sqft
    23,000 VPD

    The space is located in the Durham Center along North Main Street.

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    Turnkey Dental Office Sublease Opportunity
    Turnkey Dental Office Sublease Opportunity

    9403 Hwy 78, Ladson, SC 29456

    Contact for pricing
    42,000 sqft

    Sublease opportunity for a turnkey dental office in Ladson.

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    Flex Space Near Retail Corridor
    Flex Space Near Retail Corridor

    5515 Shakespeare Rd, Columbia, SC

    Triple net (NNN)
    Contact for pricing
    1,850 sqft

    Flex space for lease near Two Notch Rd retail corridor.

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    Office Unit
    Office Unit

    4390 Spa Dr. #Unit 2F, Little River, SC 29566

    $350/Mo
    1 person  217 sqft

    Modern finishes and a neutral color scheme allow room for tenant-specific customization.

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    Land for Lease Opportunity
    Land for Lease Opportunity

    131 Corley Mill Rd, Lexington, SC

    Contact for pricing
    2.5 acres

    Land available for lease at a busy Lexington intersection.

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    Walmart Retail Outparcel
    Walmart Retail Outparcel

    107 W Church St, Batesburg, SC 29006

    Contact for pricing
    0.72 acres

    Walmart outparcel for lease with cross access to the Walmart center and shared access with new Dunkin’ and Verizon.

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    Eastside Building Near Medical Campuses
    Eastside Building Near Medical Campuses

    800 Pelham Rd, Greenville, SC 29615

    Contact for pricing
    Built 2026

    Full building opportunity on the Eastside, near Prisma Health.

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    Office Unit
    Office Unit

    4390 Spa Dr. #Unit 2D, Little River, SC 29566

    $350/Mo
    1 person  115 sqft

    HC-zoned office space offers a compact setting for business use.

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    New Mixed-Use Development in North Augusta
    New Mixed-Use Development in North Augusta

    TBD, North Augusta, SC 29841

    Contact for pricing
    32,800 sqft

    50-acre mixed-use development with retail, residential, and senior living.

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