Erie County, NY Medical Offices for Lease

$15 SF/Yr

7,344 SF

Elmwood Avenue Professional Office Space

2555 Elmwood Ave, Buffalo, NY 14217

3,000 SF office space in high-traffic Kenmore/Elmwood corridor.

• High‑visibility location on Elmwood Avenue with strong daily traffic counts.
• 3,000 SF of flexible office space suitable for various professional uses.
• On‑site parking for staff and clients.
• Central air conditioning and forced air natural gas heating.
• Close proximity to retail, restaurants, and dense residential neighborhoods.

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Updated: Jan 13

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$499,900

5,012 SF

Spacious Commercial Building, Buffalo, NY

1609 Genesee St, Buffalo, NY 14211

Versatile commercial building with parking, suitable for various businesses.

• High‑visibility location on Genesee St with oversized parking lot (25+ spaces).
• Over 5,000 sq. ft. of versatile commercial space suitable for various business types.
• Fully accessible with elevator, wheelchair ramp, and wide hallways.
• Valid Certificate of Occupancy and ready for immediate use.
• Two‑story brick building with 4 bathrooms, laundry areas on each level, and kitchen area.

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Updated: Dec 3, 2025

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$15 SF/Yr

3,796 SF

Main St. Medical Office Space

Clarence Hollow Retail/Office Opportunity

10995 Main St, Clarence, NY 14031

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$8 SF/Yr

28,290 SF

Jefferson Utica Plaza: Medical & Office Space

Prime Erie County medical/office suites available.

1307 Jefferson Ave, Buffalo, NY 14208

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Contact for pricing

18,607 SF

West Seneca Medical Office Space

Prime Medical Office Suites Available in Buffalo, NY

550 Orchard Park Rd, West Seneca, NY 14224

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$13 SF/Yr

76,088 SF

170 Franklin Street Office Space

Historic Downtown Buffalo Office Building

172 Franklin St, Buffalo, NY 14202

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$14 SF/Yr

36,399 SF

Main Street Office Building

Prime Buffalo Office Space, 1,331-12,133 SF

1010 Main Rd, Buffalo, NY 14202

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$16 SF/Yr

38,450 SF

Delaware Ave Office Space

Prime Buffalo Office, 1,196 SF Available

936 Delaware Ave, Buffalo, NY 14209

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$5 SF/Yr

6,033 SF

Grand Island Office Space

Flexible workspace solutions in NY.

1795 Baseline Rd, Grand Island, NY 14072

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$21 SF/Yr

32,211 SF

1115 Main St Office Space

Prime Buffalo Medical Campus Office

1115 Main Rd, Buffalo, NY 14209

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$10 SF/Yr

11,512 SF

Prime Williamsville Office Building

11,512 SF Executive/Medical Office

8705 Sheridan Dr, Buffalo, NY 14221

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$14 SF/Yr

18,589 SF

Springville Medical Office Space

8,000 SF Available in Springville, NY

27 Franklin St, Springville, NY 14141

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$240 SF/Yr

15,181 SF

West Seneca Office Space Available

15,181 SF Office Building, 5,940 SF Vacant

1900 Ridge Rd, West Seneca, NY 14224

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$22 SF/Yr

51,552 SF

110 Broadway Office Space

Downtown Buffalo Office Building, Multiple Suites Available

110 Broadway St, Buffalo, NY 14203

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$12 SF/Yr

3,744 SF

Prime Medical Office Space Available

1,872 SF Medical Office for Lease

8397 Boston State Rd, Boston, NY 14025

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$5 SF/Yr

6,249 SF

Bowmansville Office Space Available

Flexible workspace solutions in Erie County.

5360 Genesee St, Bowmansville, NY 14026

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$17 SF/Yr

38,682 SF

Prime Buffalo Office Space

10,000+ SF Available, Main Street Location

1100 Main Rd, Buffalo, NY 14209

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$8 SF/Yr

12,270 SF

Kenmore Ave Office Suites

Buffalo Office Space: Flexible Lease Options

974-976 Kenmore Ave, Buffalo, NY 14216

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$18 SF/Yr

16,194 SF

Southtowns Medical Office Space

Modern medical suites, prime location.

4901 Camp Rd, Hamburg, NY 14075

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$15 SF/Yr

15,696 SF

Prime Buffalo Office Space

Class A Office Suites Available

531 Farber Lakes Dr, Buffalo, NY 14221

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$19 SF/Yr

40,000 SF

Williamsville Medical Office Building

Class A Office Space, Flexible Lease Options

1150 Youngs Rd, Buffalo, NY 14221

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$19 SF/Yr

109,880 SF

270 Michigan Ave Office Space

Buffalo CBD Office, Retail, Industrial

270 Michigan Ave, Buffalo, NY 14203

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$12 SF/Yr

4,800 SF

Elmwood Ave Office Space For Lease

Versatile Office Building, 4,500 SF Available

2282 Elmwood Ave, Buffalo, NY 14217

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$18 SF/Yr

79,112 SF

University Commons Office Park

Amherst Office Space: 1,395-2,666 SF Available

1400-1416 Sweet Home Rd, Buffalo, NY 14228

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