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    Onondaga County, NY Medical Office Space for Lease

    List
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    New York, NY Brooklyn, NY Queens, NY
    13 results
    Medical Office Space Available
    $19 SF/Yr
    5,126 SF

    Medical Office Space Available

    792 North Main Street, North Syracuse, NY 13212

    5,126 SF medical office suite for lease.

    • 5,126 RSF medical office suite featuring 9 exam rooms, 3 bathrooms, 1 nurses’ station, and 3 administrative offices.
    • Highly visible location in Village Medical Park, less than one mile from the I‑481/I‑81 interchange.
    • Ample parking (6.37:1000).
    • Proximity to Syracuse Hancock International Airport (± 3.1 miles) and downtown Syracuse/major hospitals (±8 miles).
    • Located near numerous retailers and restaurants including Wegmans, Lowes, The Home Depot, and Price Chopper.
    Updated: Mar 25
    View details
    Liverpool Medical Office Suites Available
    Contact for pricing
    18,629 SF

    Liverpool Medical Office Suites Available

    5100 West Taft Road, Liverpool, NY 13088

    Highly visible medical office suites for lease in Liverpool, NY.

    • Located in North Medical Center, a highly visible five‑story building.
    • Proximity to major roadways: near the intersection of W. Taft Road and Buckley Road.
    • Home to providers affiliated with St. Joseph‘s Health Hospital and SUNY Upstate Medical University.
    • Current tenants include Laboratory Alliance of Central New York, Eye Surgeons of Central New York, and other medical specialists.
    • Approximately 2 miles to I‑81 and 8 miles north of downtown Syracuse and major hospitals.
    Updated: Nov 22, 2025
    View details
    Cicero Medical & Office Spaces
    $16 SF/Yr
    2,500 SF

    Cicero Medical & Office Spaces

    Medical and office spaces for lease in Cicero, NY.

    6221 Rte 31, Cicero, NY
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    Medical Building with Flexible Suites
    Contact for pricing
    5,000 SF

    Medical Building with Flexible Suites

    Professional medical building with suites available for lease.

    2112 Erie Blvd E, Syracuse, NY
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    Office/Retail Building Near Micron Site
    $21 SF/Yr
    19,800 SF

    Office/Retail Building Near Micron Site

    New construction office/retail space available near Micron site.

    4597 NY-31, Clay, NY
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    Medical Office Space For Rent
    $29 SF/Yr
    3,952 SF

    Medical Office Space For Rent

    3952 SF medical office space with high visibility.

    5417 W Genesee St, Camillus, NY
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    Office/Retail Building Near Micron Site
    $21 SF/Yr
    6,200 SF

    Office/Retail Building Near Micron Site

    Office and retail spaces available near the new Micron site.

    4591 State Route 31, Clay, NY 13041
    View details
    Cicero Office Space For Lease
    Contact for pricing
    1,800 SF

    Cicero Office Space For Lease

    1,800 SF office space in Cicero business park.

    5620 Business Ave, Cicero, NY 13039
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    New Development Opportunity in Syracuse
    Contact for pricing
    26,000 SF

    New Development Opportunity in Syracuse

    New Class A medical/office or office/warehouse facility for lease.

    6731 Fly Rd, East Syracuse, NY
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    Downtown Syracuse Office Space Available
    $15 SF/Yr
    11,936 SF

    Downtown Syracuse Office Space Available

    Medical or general office space for lease in Syracuse.

    600 E Genesee St, Syracuse, NY
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    Kirkville Road Medical/Office Suites
    Contact for pricing
    710 SF

    Kirkville Road Medical/Office Suites

    Medical/office suites for lease near I-481 in East Syracuse.

    6700 Kirkville Rd, E Syracuse, NY
    View details
    Class A Office Building Syracuse
    Contact for pricing
    14,000 SF

    Class A Office Building Syracuse

    Professionally managed multi-tenant office building with medical and traditional spaces.

    1304 Buckley Rd, Syracuse, NY 13212
    View details
    Medical Office Near Route 481
    $25 SF/Yr

    Medical Office Near Route 481

    Medical office space with convenient access and ample parking.

    4939 Brittonfield Pkwy, East Syracuse, NY 13057
    View details
    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 13 Active listings in Onondaga County, NY, we suggest exploring alternatives. Similar 7 Properties for Sales.

    Explore Similar Spaces for Sale in Onondaga County, NY

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Modern Class A Office Building
    $4,500,000
    40,625 SF

    Modern Class A Office Building

    40,625 SF office building ideal for medical or conventional use.

    5062 Brittonfield Pkwy, East Syracuse, NY
    View details
    Medical Office Building For Sale
    $1,800,000
    10,000 SF

    Medical Office Building For Sale

    10,000 SF medical office building with available space.

    5639 W Genesee St, Camillus, NY 13031
    View details
    Mixed-Use Building with Dental Practice
    $185,000
    2,600 SF

    Mixed-Use Building with Dental Practice

    2600 SF building with dental practice and apartment.

    1500 Grant Blvd and Mayar St, Syracuse, NY
    View details
    Freestanding Commercial Building on Erie
    $450,000
    4,200 SF

    Freestanding Commercial Building on Erie

    4,200 SF commercial building on Erie Blvd available for sale.

    1810 Erie Blvd E, Syracuse, NY 13210
    View details
    Medical Office & Vacant Land
    $4,750,000
    4.54 Acres

    Medical Office & Vacant Land

    4.54 acres with medical office and 3 acres vacant.

    5569 Legionnaire Dr, Cicero, NY
    View details
    Well-Maintained Two-Story Office Building
    $1,695,000
    22,867 SF

    Well-Maintained Two-Story Office Building

    Two-story office building with basement and excellent onsite parking.

    5232 Witz Dr, N Syracuse, NY
    View details
    Multi-Tenant Office Building For Sale
    $899,000
    15,200 SF

    Multi-Tenant Office Building For Sale

    Stand-alone office building with ample parking and convenient access.

    716 James St, Syracuse, NY 13203
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
    View details
    Prime Commercial Lot For Rent
    $7,500 /Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Winter Park Mixed-Use Opportunity
    $8,500 /Mo
    23,056 SF

    Winter Park Mixed-Use Opportunity

    Double commercial lot in Winter Park, FL, for lease.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details

    Onondaga County, NY Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Onondaga County, NY with 13 listings featured on our commercial real estate exchange. The current inventory includes 1,364,560,560 square feet of properties with an estimated lease value of $52 SF/Yr.

    Estimated lease rates for Medical Office Space in Onondaga County, NY begin at $12 SF/Yr, with an average of $17 SF/Yr and extend to $21 SF/Yr.
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