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    Onondaga County, NY Medical Office Space for Lease

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    New York, NY Brooklyn, NY Bronx, NY
    14 results
    Medical Office Space Available
    $19 SF/Yr
    5,126 SF

    Medical Office Space Available

    792 North Main Street, North Syracuse, NY 13212

    5,126 SF medical office suite for lease.

    • 5,126 RSF medical office suite featuring 9 exam rooms, 3 bathrooms, 1 nurses’ station, and 3 administrative offices.
    • Highly visible location in Village Medical Park, less than one mile from the I‑481/I‑81 interchange.
    • Ample parking (6.37:1000).
    • Proximity to Syracuse Hancock International Airport (± 3.1 miles) and downtown Syracuse/major hospitals (±8 miles).
    • Located near numerous retailers and restaurants including Wegmans, Lowes, The Home Depot, and Price Chopper.
    Updated: Mar 25
    View details
    Turnkey Medical Office Space Available
    $355,000 SF/Yr

    Turnkey Medical Office Space Available

    127-29 Seeley Rd, Syracuse, NY 13224

    Professionally renovated medical office with suites, kitchen, and ample parking.

    • Turnkey medical office space, ready for immediate occupancy.
    • Prime location with easy access to major routes (690, 81, 481, NYS Thruway).
    • Professionally renovated building in excellent condition.
    • Spacious layout with 3000+ sq‑ft, featuring 10 suites, kitchen, office areas, and storage.
    • Ample parking with 25+ spaces.
    Updated: Nov 27, 2025
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    Cicero Medical & Office Spaces
    $16 SF/Yr
    2,500 SF

    Cicero Medical & Office Spaces

    Medical and office spaces for lease in Cicero, NY.

    6221 Rte 31, Cicero, NY
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    Liverpool Medical Office Suites Available
    Contact for pricing
    18,629 SF

    Liverpool Medical Office Suites Available

    Highly visible medical office suites for lease in Liverpool, NY.

    5100 West Taft Road, Liverpool, NY 13088
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    Modern Medical and Office Space
    Contact for pricing
    33,548 SF

    Modern Medical and Office Space

    Three floors of modern medical and office space for rent.

    1304 Buckley Road, Syracuse, NY 13212
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    Office/Retail Building Near Micron Site
    $21 SF/Yr

    Office/Retail Building Near Micron Site

    New office/retail building with build-to-suit options near Micron.

    4591 State Route 31 Hwy, Clay, NY 13041
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    East Syracuse Medical Office Conversion
    Contact for pricing
    40,625 SF

    East Syracuse Medical Office Conversion

    Class A medical office conversion near downtown hospitals.

    5062 Brittonfield Parkway, East Syracuse, NY 13057
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    Office/Retail Building Near Micron Site
    $21 SF/Yr
    19,800 SF

    Office/Retail Building Near Micron Site

    New construction office/retail space available near Micron site.

    4597 NY-31, Clay, NY
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    Medical Office Space For Rent
    $29 SF/Yr
    3,952 SF

    Medical Office Space For Rent

    3952 SF medical office space with high visibility.

    5417 W Genesee St, Camillus, NY
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    Medical Building with Flexible Suites
    Contact for pricing
    5,000 SF

    Medical Building with Flexible Suites

    Professional medical building with suites available for lease.

    2112 Erie Blvd E, Syracuse, NY
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    Office/Retail Building Near Micron Site
    $21 SF/Yr
    6,200 SF

    Office/Retail Building Near Micron Site

    Office and retail spaces available near the new Micron site.

    4591 State Route 31, Clay, NY 13041
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    Downtown Syracuse Office Space Available
    $15 SF/Yr
    11,936 SF

    Downtown Syracuse Office Space Available

    Medical or general office space for lease in Syracuse.

    600 E Genesee St, Syracuse, NY
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    New Development Opportunity in Syracuse
    Contact for pricing
    26,000 SF

    New Development Opportunity in Syracuse

    New Class A medical/office or office/warehouse facility for lease.

    6731 Fly Rd, East Syracuse, NY
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    Kirkville Road Medical/Office Suites
    Contact for pricing
    710 SF

    Kirkville Road Medical/Office Suites

    Medical/office suites for lease near I-481 in East Syracuse.

    6700 Kirkville Rd, E Syracuse, NY
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    Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 14 Active listings in Onondaga County, NY, we suggest exploring alternatives. Similar 7 Properties for Sales.

    Similar Spaces for Sale in Onondaga County, NY

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    North Syracuse Medical Office Building
    $400,000
    2,244 SF
    North Syracuse Medical Office Building

    Well-maintained medical office in a high-growth area.

    105 N Main Street, Syracuse, NY 13212

    View details
    Modern Class A Office Building
    $4,500,000
    40,625 SF
    Modern Class A Office Building

    40,625 SF office building ideal for medical or conventional use.

    5062 Brittonfield Pkwy, East Syracuse, NY

    View details
    Medical Office Building For Sale
    $1,800,000
    10,000 SF
    Medical Office Building For Sale

    10,000 SF medical office building with available space.

    5639 W Genesee St, Camillus, NY 13031

    View details
    Medical Office Building For Sale
    Contact for pricing
    10,000 SF
    Medical Office Building For Sale

    10,000 SF medical office building with lease options.

    5639 W Genesee St, Camillus, NY 13031

    View details
    Mixed-Use Building with Dental Practice
    $185,000
    2,600 SF
    Mixed-Use Building with Dental Practice

    2600 SF building with dental practice and apartment.

    1500 Grant Blvd and Mayar St, Syracuse, NY

    View details
    Well-Maintained Two-Story Office Building
    $1,695,000
    22,867 SF
    Well-Maintained Two-Story Office Building

    Two-story office building with basement and excellent onsite parking.

    5232 Witz Dr, N Syracuse, NY

    View details
    Medical Office & Vacant Land
    $4,750,000
    4.54 Acres
    Medical Office & Vacant Land

    4.54 acres with medical office and 3 acres vacant.

    5569 Legionnaire Dr, Cicero, NY

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Pad Site for Lease
    Contact for pricing

    Prime Pad Site for Lease

    Highly visible 1.74 acre pad site in Belmont, NH.

    9 Old State Rd, Belmont, NH 3220
    View details
    Beaumont Centre Outparcel Opportunity
    Contact for pricing

    Beaumont Centre Outparcel Opportunity

    Outparcel opportunity in established shopping center for ground lease.

    3199 Beaumont Centre Circle, Lexington, KY 40513
    View details
    Prime Lexington Outlot Opportunity
    Contact for pricing

    Prime Lexington Outlot Opportunity

    Outlot for ground lease or build-to-suit in South Lexington.

    3330 Partner Place, Lexington, KY 40503
    View details
    Kingery Highway Commercial Development Opportunity
    $85,000 SF/Yr

    Kingery Highway Commercial Development Opportunity

    High-visibility land for retail, car wash, or medical development.

    8501 & 8511 Kingery Highway, Willowbrook, IL 60527
    View details

    Onondaga County, NY Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Onondaga County, NY with 14 listings featured on our commercial real estate exchange. The current inventory includes 49,514 square feet of properties with an estimated lease value of $122 SF/Yr.

    Estimated lease rates for Medical Office Space in Onondaga County, NY begin at $15 SF/Yr, with an average of $20 SF/Yr and extend to $29 SF/Yr.
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    Medical Office Space by market

    Browse Medical Office Space for Lease Near Onondaga, NY

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