Lee County, FL Commercial Real Estate for Sale

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1,983 properties
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Waterfront Resort Property
Waterfront Resort Property

12200 /12210 Shoreview Dr, Matlacha, FL 33993

$3,250,000
7,400 sqft 1.00 AC lot

Renovated in 2025 with two buildings, boat slips, and direct waterfront positioning.

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Commercial Land with Existing Structures
Commercial Land with Existing Structures

1446 Periwinkle Way, Sanibel, FL 33957

$2,495,000
1.20 AC lot

Two commercial parcels include three existing structures along Periwinkle Way.

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Industrial Redevelopment Land
Industrial Redevelopment Land

204-212 3rd St, Fort Myers, FL 33907

$2,200,000
12,979 sqft 3.86 AC lot

Redevelopment-ready industrial and commercial site with IL and C-2 zoning for warehouse, yard, or flex use.

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Move-In-Ready Office Condo Suite
Move-In-Ready Office Condo Suite

C1-5235 Ramsey Way, Fort Myers, FL 33907

$199,900
880 sqft

Nearly 900 sq. ft. office condo has new flooring and fresh paint, ready for immediate professional use.

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Waterfront Commercial Land
Waterfront Commercial Land

7760 Bocilla Lane, Bokeelia, FL 33922

$975,000
0.46 AC lot

CT-zoned parcel with public water and sewer service.

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Mixed-Use Duplex with Commercial Space
Mixed-Use Duplex with Commercial Space

2826 Santa Barbara Boulevard, Cape Coral, FL 33914

$429,000
2,406 sqft

MR zoning supports a live-work arrangement with commercial and residential components.

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Commercial Land with Development Plans
Commercial Land with Development Plans

1415 Cape Coral Parkway E, Cape Coral, FL 33904

$2,490,000
0.33 AC lot

Planned mixed-use project combines residential, executive office, and café components in downtown Cape Coral.

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Entitled Mixed-Use Commercial Land
Entitled Mixed-Use Commercial Land

3731 SE 15th Place, Cape Coral, FL 33904

$975,000
1.03 AC lot

C1-zoned development site with approved plans for workforce housing and commercial space in a six-story building.

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Prime Commercial Land Opportunity
Prime Commercial Land Opportunity

16984 McGregor Blvd., Fort Myers, FL 33908

$3,250,000
4 sqft 4.30 AC lot

4.3-acre commercial site in a rapidly growing South Fort Myers market.

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C-1A Commercial Land
C-1A Commercial Land

4901 Buckingham Road, Fort Myers, FL 33905

$1,799,000
3.28 AC lot

The parcel has C-1A zoning and is served by well water and a septic system.

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Commercial Land with Existing Structure
Commercial Land with Existing Structure

185 Old San Carlos Boulevard, Fort Myers Beach, FL 33931

$1,500,000
0.10 AC lot

CB zoning supports retail, restaurant, office, hospitality, residential, and mixed-use applications.

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Medical Office Condo in Grey Shell
Medical Office Condo in Grey Shell

217 Del Prado Boulevard S, Cape Coral, FL 33990

$650,000
0.74 AC lot

Medical-use condominium with a customizable interior layout, paid impact fees, and on-site parking.

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Flex Space with Fenced Area
Flex Space with Fenced Area

6241 Arc Way, Fort Myers, FL 33966

$1,495,000
0.69 AC lot

Adaptable industrial property with offices, kitchen areas, garages, and enclosed outdoor space.

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Leased Storefront Property
Leased Storefront Property

1950 Ricardo Avenue, Fort Myers, FL 33901

$450,000
0.16 AC lot

An existing four-year lease provides rental income from an established business.

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Single-Tenant NNN Property
Single-Tenant NNN Property

14361 N CLEVELAND AVE, North Fort Myers, FL 33907

Contact for pricing
10,205 sqft 2.02 AC lot

Freestanding showroom and warehouse with an absolute-net leaseback and direct US-41 frontage.

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Gulf-Front Waterfront Land
Gulf-Front Waterfront Land

4360 Estero Blvd lot: 1, Fort Myers Beach, FL 33931

$4,975,000
0.30 AC lot

CR-zoned land directly on the Gulf beach with cable availability and mixed residential land use.

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Downtown Storefront Property
Downtown Storefront Property

820 Cape Coral Pkwy E, Cape Coral, FL 33904

$899,000
2,100 sqft 0.07 AC lot

Leased commercial building along Cape Coral Parkway with recent roof and interior improvements.

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Two-Unit Flex Space
Two-Unit Flex Space

3559 Veronica S Shoemaker Blvd, Fort Myers, FL 33916

Contact for pricing
5,760 sqft 0.44 AC lot

Each suite pairs warehouse capacity with an office, private restroom, and automatic overhead door.

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Fenced Live-Work Property
Fenced Live-Work Property

2850 Packinghouse Road, Alva, FL 33920

$380,000
1.88 AC lot

AG-2 property with multiple offices, open work areas, covered space, and detached buildings.

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Flex Building With Drive-Through Bays
Flex Building With Drive-Through Bays

6100 Idlewild St, Fort Myers, FL 33966

Contact for pricing
8,309 sqft

Fenced flex facility with repair-bay configuration, secured outdoor storage, and ongoing office and building improvements.

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Warehouse Property with Updated Systems
Warehouse Property with Updated Systems

26340 Old 41 Road, Bonita Springs, FL 34135

$4,950,000
1.02 AC lot

Warehouse property with four new A/C units and refreshed electrical and plumbing systems in Bonita Springs.

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Cape Coral Warehouse For Sale
Cape Coral Warehouse For Sale

847-905 Southeast 9th Terrace, Cape Coral, FL 33990

$8,700,000
50,400 sqft

Professionally managed warehouse in Mid-Cape Industrial area, Cape Coral.

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Office Suite with Loft
Office Suite with Loft

2323 Wooster Lane, Sanibel, FL 33957

$329,000
0.11 AC lot

An adaptable work area pairs an open floor plan with separate elevated storage.

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Eight-Unit Waterfront Resort
Eight-Unit Waterfront Resort

3226 Stringfellow Road, St James City, FL 33956

$1,649,900
0.44 AC lot

Renovated studio accommodations include kitchens, private baths, outdoor living areas, and direct canal access.

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