Lee County, FL Medical Office Space for Rent & Lease

Updated: Feb 15

Fort Myers Beach Retail/Office Space

6035 Estero Boulevard, Fort Myers Beach, FL 33931

$21/Mo

1,420 sqft

High‑visibility location with 132 feet of frontage on Estero Boulevard
Versatile 1,420 RSF space suitable for office, retail, medical, restaurant, or wellness use
Recently renovated with impact windows and doors, updated electrical, new flooring, renovated bathrooms, and new A/C systems
Located near the recently relocated Town Hall
Ample parking and attractive landscaping

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Updated: Apr 7

Medical Office Space in Healthcare Corridor

13195 Metro Parkway, Fort Myers, FL 33966

$3,250/Mo

Strategic location within a rapidly expanding healthcare corridor in Fort Myers.
Close proximity to multiple Lee Health facilities, including the newly constructed hospital campus and Gulf Coast Medical Center.
Ideally suited for medical, wellness, and service‑oriented users.
High concentration of physician offices, outpatient services, and medical businesses in the surrounding area.
Direct access to key roadways such as Colonial Boulevard and Daniels Parkway.

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Medical Office Suite

11380 Bonita Beach Road SE, Bonita Springs, FL 34135

$3,472/Mo

Grey shell medical/office space in a newer construction building, available now for tenant customization.

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Medical Office Condo with Signage

14131 Metropolis Ave, Fort Myers, FL 33912

$27 SF/Yr

2,000 sqft

Lease a 2,000 SF medical/professional condo in a multi-tenant building with Metro Parkway frontage and signage options.

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Move-In Ready Medical Office Suite

1224 Del Prado Boulevard S, Cape Coral, FL 33990

$17/Mo

Remodeled office and medical-ready layout with multiple private entrances, reception area, and dedicated parking.

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Turnkey Fourth-Floor Office Suite

3949 Evans Avenue, Fort Myers, FL 33901

$12/Mo

Move-in ready suite with reception, five offices, and an in-unit washer/dryer in a central Fort Myers corridor.

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Built-Out Office Unit with Parking

40 Barkley Circle, Fort Myers, FL 33919

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Key West style office suites for lease with built-out interior space and shared parking near major Fort Myers arterials.

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Renovated Office/Medical Building For Rent

4048 Evans Ave, Fort Myers, FL 33901

$20 SF/Yr

16,000 sqft

Fully renovated office building with modern space and abundant parking.

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Flexible Medical Office Suite

1949 Maravilla Avenue, Fort Myers, FL 33901

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Adaptable office suite previously used as a dental laboratory, delivered without equipment for medical or professional use.

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Medical Office Suite with 7 Offices

45 Barkley Circle, Fort Myers, FL 33907

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Move-in-ready suite with seven private offices, oversized break room, and covered parking.

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Modern Office Suites in Fort Myers

12751 S Cleveland Ave, Fort Myers, FL 33907

$20 SF/Yr

5,408 sqft

Professional office suites with frontage on US-41 in Fort Myers.

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Ground-Floor Medical Office Condo

14131 Metropolis Avenue, Fort Myers, FL 33912

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Move-in-ready ground-floor suite in an established medical park, designated as Suite 105.

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Renovated Office Space Near Hospital

14090 Metropolis Avenue, Fort Myers, FL 33912

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Move-in ready medical/business office space near Gulf Coast Hospital.

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Prime Commercial Space for Lease

20 Barkley Circle, Fort Myers, FL 33907

$22 SF/Yr

20,516 sqft

Commercial space with great exposure and accessibility in central location.

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Fort Myers Office Space Available

13515 Bell Tower Drive, Fort Myers, FL 33907

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7,080 sqft

Class "B" office building ideal for medical or professional use.

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Fort Myers Office Space Available

6300 Corporate Court, Fort Myers, FL 33919

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Two office suites available in Fort Myers, move-in ready.

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Prime Fort Myers Commercial Space

7130 College Parkway, Fort Myers, FL 33907

$32.25 SF/Yr

2,340 sqft

Customizable 2,340 SF space for medical, retail, or service uses.

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Cape Coral Office Spaces Available

2534 SE Santa Barbara Pl, Cape Coral, FL 33904

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750 sqft

Class A office building with medical and executive spaces for lease.

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COMMERCIAL - Fort Myers Beach, FL

6035 Estero Blvd, Fort Myers Beach, FL 33931

$21 SF/Yr

1420 RSF suite with high visibility on Estero Boulevard.

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Bonita Springs Retail/Office Space

11380 Bonita Beach Rd SE, Bonita Springs, FL

$26 SF/Yr

1,323 sqft

Retail or professional office space with prominent signage available for lease.

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Medical Office Space For Rent

19451 S Tamiami Trl, Fort Myers, FL 33908

$32.50 SF/Yr

Well-maintained medical office space with high visibility and accessibility.

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Medical Office Space For Rent

12670 New Brittany Blvd, Fort Myers, FL 33907

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3,352 sqft

Fully built-out medical space in central Fort Myers location.

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Mixed-Use Development in Fort Myers

1380-1400 Colonial Blvd, Fort Myers, FL 33907

$30 SF/Yr

40,000 sqft

Mixed-use development with retail, office, and medical spaces for lease.

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Versatile Commercial Space Available

18070 S Tamiami Trl, Fort Myers, FL 33908

$20 SF/Yr

Commercial space with C1A zoning, ideal for various uses.

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Lee County, FL Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Lee County, FL with 35 listings featured on our commercial real estate exchange. The current inventory includes 118,074 square feet of properties with an estimated lease value of $296.75 SF/Yr.

Estimated lease rates for Medical Office Space in Lee County, FL begin at $15 SF/Yr, with an average of $22.83 SF/Yr and extend to $32.25 SF/Yr.