Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Lee County, FL Commercial Real Estate for Lease

    List
    Map
    Miami, FL Jacksonville, FL Orlando, FL
    556 results
    Medical Office Space For Rent
    $3,250 /Mo

    Medical Office Space For Rent

    13195 Metro Parkway, Fort Myers, FL 33966

    Located in a rapidly expanding healthcare corridor in Fort Myers.

    • Strategic location within a rapidly expanding healthcare corridor in Fort Myers.
    • Close proximity to multiple Lee Health facilities, including the newly constructed hospital campus and Gulf Coast Medical Center.
    • Ideally suited for medical, wellness, and service‑oriented users.
    • High concentration of physician offices, outpatient services, and medical businesses in the surrounding area.
    • Direct access to key roadways such as Colonial Boulevard and Daniels Parkway.
    Updated: Apr 7
    View details
    Downtown Fort Myers Commercial Space
    $6,168 /Mo

    Downtown Fort Myers Commercial Space

    2400 1st Street, Fort Myers, FL 33901

    Move-in ready first-floor commercial space in historic downtown.

    • Prime first‑floor location on Lee Street in the Historic Downtown River District.
    • High foot traffic and exposure due to proximity to established businesses, new developments, and 500 nearby apartments.
    • Large windows and spacious front porch providing natural light and a relaxing workspace.
    • Modified gross lease with electric, water, and CAM included.
    • Private suite restroom and small kitchen sink area.
    Updated: Apr 17
    View details
    Cape Coral Office Space Available
    $1,975 /Mo

    Cape Coral Office Space Available

    Professional office space for rent in Cape Coral, Florida.

    4020 Del Prado Boulevard S, Cape Coral, FL 33904
    View details
    Well-Maintained Office Suite For Rent
    $1,550 /Mo

    Well-Maintained Office Suite For Rent

    Office suite with private offices and shared conference room.

    3403 Hancock Bridge Parkway, North Fort Myers, FL 33903
    View details
    Cape Coral First Floor Office
    $2,250 /Mo

    Cape Coral First Floor Office

    883 SF office space available in April 2026.

    923 Del Prado Boulevard S, Cape Coral, FL 33990
    View details
    Cape Coral Retail Space Available
    $3,800 /Mo

    Cape Coral Retail Space Available

    Retail space in South Cape District with open floor plan.

    1309-B SE 47th Terrace, Cape Coral, FL 33904
    View details
    Cape Coral Commercial Office Space
    $2,500 /Mo

    Cape Coral Commercial Office Space

    Multi-tenant office building with warehouse space available for rent.

    4427 SE 16th Place, Cape Coral, FL 33904
    View details
    Cape Coral Industrial Building For Rent
    $4,150 /Mo

    Cape Coral Industrial Building For Rent

    Industrial building with office and warehouse space available for rent.

    954 Country Club Boulevard, Cape Coral, FL 33990
    View details
    North Fort Myers Commercial Opportunity
    $500 /Mo

    North Fort Myers Commercial Opportunity

    Commercial spaces for rent with high-visibility frontage.

    583 Pondella Road, North Fort Myers, FL 33903
    View details
    North Fort Myers Retail Space
    $1,200 /Mo

    North Fort Myers Retail Space

    Commercial unit for lease in North Fort Myers, Florida.

    710 Pondella Road, North Fort Myers, FL 33903
    View details
    Cape Coral Executive Office Suite
    $1,700 /Mo

    Cape Coral Executive Office Suite

    Move-in ready office space near City Hall with flexible layout.

    1212 Country Club Boulevard, Cape Coral, FL 33990
    View details
    Luxury Office in Coconut Point
    $21 SF/Yr

    Luxury Office in Coconut Point

    Upscale office space in a vibrant mixed-use destination.

    23190 Fashion Drive, Estero, FL 33928
    View details
    Fort Myers Commercial Flex Space
    $17 SF/Yr

    Fort Myers Commercial Flex Space

    3,000 SF flex space available for lease in Fort Myers.

    1687 Benchmark Avenue, Fort Myers, FL 33905
    View details
    Cape Coral Flex Space Available
    $2,950 /Mo

    Cape Coral Flex Space Available

    Flex space with office and warehouse in downtown Cape Coral.

    4519 SE 16th Place, Cape Coral, FL 33904
    View details
    Fort Myers Beach Retail/Office Space
    $21 SF/Yr

    Fort Myers Beach Retail/Office Space

    1420 RSF suite with high visibility on Estero Boulevard.

    6035 Estero Boulevard, Fort Myers Beach, FL 33931
    View details
    Renovated Industrial Property in Cape Coral
    $22 SF/Yr

    Renovated Industrial Property in Cape Coral

    Renovated 4,500 SF industrial property with flexible uses.

    1002 SE 9th Street, Cape Coral, FL 33990
    View details
    Bonita Springs Medical/Office Space
    $3,472 /Mo

    Bonita Springs Medical/Office Space

    1323 SF grey shell space on Bonita Beach Road.

    11380 Bonita Beach Road SE, Bonita Springs, FL 34135
    View details
    Warehouse with Office Space Available
    $1,900 /Mo

    Warehouse with Office Space Available

    Warehouse space with office in North Cape Industrial Park.

    909 NE 27th Lane, Cape Coral, FL 33909
    View details
    Cape Coral Warehouse with Office
    $2,100 /Mo

    Cape Coral Warehouse with Office

    Warehouse space with office in North Cape Industrial Park.

    909 NE 27th Lane, Cape Coral, FL 33909
    View details
    Downtown Cape Coral Office Space
    $1,000 /Mo

    Downtown Cape Coral Office Space

    Spacious office space in the heart of downtown Cape Coral.

    4705 Vincennes Boulevard, Cape Coral, FL 33904
    View details
    Cape Coral Office/Medical Space
    $18 SF/Yr

    Cape Coral Office/Medical Space

    Recently remodeled office space suitable for medical or professional use.

    1224 Del Prado Boulevard S, Cape Coral, FL 33990
    View details
    Modern Furnished Office Spaces Available
    $2,000 /Mo

    Modern Furnished Office Spaces Available

    Two furnished office spaces for rent with included amenities.

    3850 Colonial Boulevard, Fort Myers, FL 33966
    View details
    North Fort Myers Standalone Warehouse
    $3,500 /Mo

    North Fort Myers Standalone Warehouse

    Standalone warehouse with office, bathrooms, and fenced yard for lease.

    29 Cardinal Drive, North Fort Myers, FL 33917
    View details
    Cape Coral Office Space For Rent
    $2,895 /Mo

    Cape Coral Office Space For Rent

    Approximately 1000 SF end unit in great location.

    3046 Del Prado Boulevard S, Cape Coral, FL 33904
    View details

    Lee County, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Lee County, FL with 556 listings featured on our commercial real estate exchange. The current inventory includes 207,704,156,685 square feet of properties with an estimated lease value of $2,045 /Mo.

    Estimated lease rates for Commercial real estate in Lee County, FL begin at $0.51 SF/Yr, with an average of $17 SF/Yr and extend to $75 SF/Yr.
    List
    Map

    Commercial real estate by market

    Browse Commercial real estate for Lease Near Lee, FL

    Popular Searches in Lee

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!