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    Lee County, FL Commercial Real Estate for Lease

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    Miami, FL Jacksonville, FL Orlando, FL
    554 results
    Forum Corporate
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    Medical Office Space For Rent
    $3,250/Mo

    Medical Office Space For Rent

    13195 Metro Parkway, Fort Myers, FL 33966

    Located in a rapidly expanding healthcare corridor in Fort Myers.

    • Strategic location within a rapidly expanding healthcare corridor in Fort Myers.
    • Close proximity to multiple Lee Health facilities, including the newly constructed hospital campus and Gulf Coast Medical Center.
    • Ideally suited for medical, wellness, and service‑oriented users.
    • High concentration of physician offices, outpatient services, and medical businesses in the surrounding area.
    • Direct access to key roadways such as Colonial Boulevard and Daniels Parkway.
    Updated: Apr 7
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    North Fort Myers Warehouse Space
    $3,500/Mo
    1,700 SF

    North Fort Myers Warehouse Space

    27 Cardinal Drive, North Fort Myers, FL 33917

    Versatile 1,700 SF industrial space for lease.

    • Prime North Fort Myers location with easy access to major roadways and minutes from Fort Myers.
    • Versatile 1,700 SF industrial space suitable for warehouse, contractor, storage, automotive, distribution, e‑commerce, or service‑oriented businesses.
    • Features 3 roll‑up garage doors for convenient access and operations.
    • Includes a private office area and 2 restrooms.
    • Gated access for enhanced security.
    Updated: May 2
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    New Retail Units in Plaza
    $35 SF/Yr
    1,545 SF

    New Retail Units in Plaza

    Modern retail units in high-growth area with outstanding accessibility.

    8156 Alico Rd, Fort Myers, FL 33912
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    Cape Coral Office Space Available
    $1,975/Mo
    850 SF

    Cape Coral Office Space Available

    Professional office space for rent in Cape Coral, Florida.

    4020 Del Prado Boulevard S, Cape Coral, FL 33904
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    Prime Cape Coral Office Space
    $1,750/Mo

    Prime Cape Coral Office Space

    Ground-floor office in downtown Cape Coral's CRA District.

    4645 SE 15th Avenue, Cape Coral, FL 33904
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    Cape Coral First Floor Office
    $2,250/Mo

    Cape Coral First Floor Office

    883 SF office space available in April 2026.

    923 Del Prado Boulevard S, Cape Coral, FL 33990
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    Cape Coral Retail Space Available
    $3,800/Mo

    Cape Coral Retail Space Available

    Retail space in South Cape District with open floor plan.

    1309-B SE 47th Terrace, Cape Coral, FL 33904
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    Cape Coral Commercial Office Space
    $2,500/Mo

    Cape Coral Commercial Office Space

    Multi-tenant office building with warehouse space available for rent.

    4427 SE 16th Place, Cape Coral, FL 33904
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    Cape Coral Industrial Building For Rent
    $4,150/Mo

    Cape Coral Industrial Building For Rent

    Industrial building with office and warehouse space available for rent.

    954 Country Club Boulevard, Cape Coral, FL 33990
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    Retail Storefront Suite
    $1,200/Mo
    800 SF

    Retail Storefront Suite

    800 SF unit in a busy neighborhood plaza with strong visibility and ample on-site parking, suited for retail or office uses.

    710 Pondella Road, North Fort Myers, FL 33903
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    Retail Suite at Waterfront Destination
    $1,200/Mo

    Retail Suite at Waterfront Destination

    Well-located retail space within a walkable mixed-use waterfront setting with strong destination foot traffic.

    5781 Cape Harbour Drive, Cape Coral, FL 33914
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    New Retail Space in Fort Myers
    $35 SF/Yr
    1,545 SF

    New Retail Space in Fort Myers

    Modern retail units in a high-growth area with excellent visibility.

    8156 Alico Rd, Fort Myers, FL 33912
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    Retail Space in Merchants Plaza
    $22 SF/Yr
    3,200 SF

    Retail Space in Merchants Plaza

    Retail space available in February 2026 in Cape Coral.

    159 Hancock Bridge Parkway, Cape Coral, FL 33990
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    Cape Coral Executive Office Suite
    $1,700/Mo

    Cape Coral Executive Office Suite

    Move-in ready office space near City Hall with flexible layout.

    1212 Country Club Boulevard, Cape Coral, FL 33990
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    Cape Coral Flex Office Warehouse
    $1,920/Mo
    1,152 SF

    Cape Coral Flex Office Warehouse

    Flex office warehouse building in central Cape Coral location.

    829 NE Pine Island Lane, Cape Coral, FL 33909
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    Cape Coral Flex Space Available
    $2,950/Mo

    Cape Coral Flex Space Available

    Flex space with office and warehouse in downtown Cape Coral.

    4519 SE 16th Place, Cape Coral, FL 33904
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    Downtown Fort Myers Commercial Space
    $5,850/Mo

    Downtown Fort Myers Commercial Space

    Move-in ready first-floor space in the Historic Downtown River District.

    2400 1st Street, Fort Myers, FL 33901
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    Renovated Industrial Property in Cape Coral
    $22 SF/Yr

    Renovated Industrial Property in Cape Coral

    Renovated 4,500 SF industrial property with flexible uses.

    1002 SE 9th Street, Cape Coral, FL 33990
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    Bonita Springs Medical/Office Space
    $3,472/Mo

    Bonita Springs Medical/Office Space

    1323 SF grey shell space on Bonita Beach Road.

    11380 Bonita Beach Road SE, Bonita Springs, FL 34135
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    Office Space in Fort Myers
    $1,250/Mo

    Office Space in Fort Myers

    Office space for rent at College Parkway and Kenwood Lane.

    7181 College Parkway, Fort Myers, FL 33907
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    Warehouse with Office Space Available
    $1,900/Mo

    Warehouse with Office Space Available

    Warehouse space with office in North Cape Industrial Park.

    909 NE 27th Lane, Cape Coral, FL 33909
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    Cape Coral Warehouse with Office
    $2,100/Mo

    Cape Coral Warehouse with Office

    Warehouse space with office in North Cape Industrial Park.

    909 NE 27th Lane, Cape Coral, FL 33909
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    Downtown Cape Coral Office Space
    $1,000/Mo

    Downtown Cape Coral Office Space

    Spacious office space in the heart of downtown Cape Coral.

    4705 Vincennes Boulevard, Cape Coral, FL 33904
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    Lee County, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Lee County, FL with 554 listings featured on our commercial real estate exchange. The current inventory includes 2,835,484 square feet of properties with an estimated lease value of $244,568.

    Estimated lease rates for Commercial real estate in Lee County, FL begin at $0.67 SF/Yr, with an average of $1,247 /Mo and extend to $47,400.
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