Osceola County, FL Commercial Real Estate for Sale

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Updated: Aug 18

Multi-Suite Medical Office Building

323 W CYPRESS Street, Kissimmee, FL 34741

$1,500,000

4,551 sqft 0.44 AC lot

4,551 SF medical office building on a 0.44‑acre corner lot
Approximately 26 rooms, including exam rooms, private offices, and clinic areas
6 restrooms, dedicated waiting room, and multiple reception or lobby areas
Three addressable units at 323, 325, and 327 W. Cypress St.
19 parking spaces, including handicap spaces

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Updated: Sep 10

Single-Level Office Building

1201 E OAK Street, Kissimmee, FL 34744

$5,000,000

14,652 sqft 2.09 AC lot

14,652‑square‑foot office building on 2.09 acres
77 parking spaces and 300 feet of frontage on E Oak Street
More than 7,000 square feet of open, undivided interior space
Seven flex areas for offices, conference rooms, kitchen, or storage
Built in 2005 with four bathrooms and multiple stalls

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Renovated Office Building

104 S CLYDE Avenue, Kissimmee, FL 34741

$569,000

1,887 sqft 0.34 AC lot

Flexible professional layout supports single-user occupancy or separate business suites with private entrances.

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See what stands out in Osceola County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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Single-Level Office Building

1201 E OAK, Kissimmee, FL 34744

$5,000,000

15,000 sqft 2.00 AC lot

Flexible commercial building with open work areas, private rooms, multiple bathrooms, and substantial on-site parking.

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Industrial Flex Property

4411 TAMI Lane, Kissimmee, FL 34746

$3,250,000

7,850 sqft 2.54 AC lot

Combines private offices with an open warehouse and five grade-level bay doors for loading, storage, and service operations.

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Mixed-Use Building with Retail Frontage

4560 W IRLO BRONSON MEMORIAL Highway, Kissimmee, FL 34746

$950,000

1,315 sqft 3.76 AC lot

Under-construction commercial project combining professional office and retail space along Kissimmee’s W Irlo Bronson Memorial Hwy corridor.

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Two-Tenant Office Building

Saint Cloud, FL 34769

$600,000

2,346 sqft 0.17 AC lot

Downtown office property with leased occupancy, recent roof and AC improvements, and on-site parking.

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Office Building with Medical Buildout

323 W Cypress Street, Kissimmee, FL 34741

$1,500,000

4,620 sqft

Corner office property with multiple suites, clinical rooms, separate metering, and flexible occupancy options near two hospitals.

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Waterfront Hotel and Café

Saint Cloud, FL 34771

$2,850,000

6,430 sqft 1.13 AC lot

Four-building hospitality property with lake access, pavilion, and on-site kitchen facilities.

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Retail Storefront with Inventory

6119 W IRLO BRONSON MEMORIAL Highway, Kissimmee, FL 34746

$165,000

4,410 sqft

Souvenir gift shop with inventory, fixtures, equipment, and machines included.

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Flex Space with Warehouse Bays

4411 Tami Ln, Kissimmee, FL 34746

$3,250,000

7,850 sqft 2.54 AC lot

Acreage, private offices, restrooms, and grade-level access support combined office and industrial operations.

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Grocery Store With Restaurant

131 BUENAVENTURA Boulevard, Kissimmee, FL 34743

$389,999

8,800 sqft 0.58 AC lot

Established market and food-service operation with Caribbean and Latin products, dine-in seating, and takeout service.

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Freestanding Storefront Building

820 N MAIN Street, Kissimmee, FL 34744

$520,000

1,530 sqft 0.10 AC lot

KB3-zoned commercial property with central air and flexible retail-oriented use potential.

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Single-Story Retail/Office Shell with Patio

5068 Old Tampa Hwy 04, Kissimmee, FL 34758

$2,502,500

7,149 sqft

Newly constructed shell with customizable interior and a private patio end cap for retail or office users.

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Downtown Mixed-Use Building

12 E DARLINGTON Avenue, Kissimmee, FL 34741

$2,650,000

3,112 sqft 0.09 AC lot

Brick commercial building with central air on a visible corner site near downtown services, transit, and public parking.

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Mixed-Use Building with Office Units

4560 W IRLO BRONSON MEMORIAL Highway, Kissimmee, FL 34746

$220,000

220 sqft 3.76 AC lot

New construction combines small-format office suites with dedicated retail space for professional and business users.

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Single-Story Retail or Office Suite

5028 Old Tampa Hwy 07, Kissimmee, FL 34758

$1,867,600

5,336 sqft

Under construction single-story building delivered in dark gray shell with customizable interior for retail or office use.

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Office Building with Secured Lease

Saint Cloud, FL 34769

$459,900

1,752 sqft 0.04 AC lot

Block-built commercial office asset with central HVAC, public utilities, and an in-place tenancy extending through February 2028.

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Single-Story Retail/Office with Drive-Through

5080 Old Tampa Hwy Unit 03, Kissimmee, FL 34758

$1,456,000

4,181 sqft

Under construction single-story shell with customizable interior, approved drive-through, and shared patio near major retail traffic.

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Office Units with Existing Lease

Saint Cloud, FL 34769

$459,900

1,742 sqft 0.04 AC lot

Office property with a tenant lease extending through December 2029 and public water and sewer service.

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Single-Story Retail and Office Building

5086 Old Tampa Hwy Unit 02, Kissimmee, FL 34758

$1,993,600

5,545 sqft

Under-construction building #02 in a mixed-use exchange with flexible interior design and shared patio space.

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Office Unit with Lease in Place

Saint Cloud, FL 34769

$459,900

1,727 sqft 0.04 AC lot

Existing tenancy extends through January 2028.

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Single-Story Retail and Office Building

5028 Old Tampa Hwy Unit 07, Kissimmee, FL 34758

$1,867,600

5,336 sqft

Single-story building delivered in shell condition with customizable interior at a major retail intersection.

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Downtown Office Building with Parking

1007 EMMETT Street, Kissimmee, FL 34741

$495,000

2,501 sqft 0.25 AC lot

Standalone professional office property with dedicated parking and central HVAC near courthouse and government offices.

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Osceola County, FL Commercial Real Estate Market Trends and Statistics

Explore 385 commercial real estate for sale in Osceola County, FL, showcased through 385 active listings on our real estate platform. These investment opportunities span a total of 987,716 square feet of properties for sale, with an estimated market value of $479,829,817.

Sale prices for business properties in Osceola County, FL start at $32,400, averaging $1,552,847, and reaching up to $15,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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