Osceola County, FL Commercial Real Estate for Sale

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382 properties
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Multi-Suite Medical Office Building
Updated: Aug 18
Multi-Suite Medical Office Building

323 W CYPRESS Street, Kissimmee, FL 34741

$1,500,000
4,551 sqft 0.44 AC lot
4,551 SF medical office building on a 0.44‑acre corner lot
Approximately 26 rooms, including exam rooms, private offices, and clinic areas
6 restrooms, dedicated waiting room, and multiple reception or lobby areas
Three addressable units at 323, 325, and 327 W. Cypress St.
19 parking spaces, including handicap spaces
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Single-Level Office Building
Updated: Sep 10
Single-Level Office Building

1201 E OAK Street, Kissimmee, FL 34744

$5,000,000
14,652 sqft 2.09 AC lot
14,652‑square‑foot office building on 2.09 acres
77 parking spaces and 300 feet of frontage on E Oak Street
More than 7,000 square feet of open, undivided interior space
Seven flex areas for offices, conference rooms, kitchen, or storage
Built in 2005 with four bathrooms and multiple stalls
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Mixed-Use Building with Retail Frontage
Mixed-Use Building with Retail Frontage

4560 W IRLO BRONSON MEMORIAL Highway, Kissimmee, FL 34746

$950,000
1,315 sqft 3.76 AC lot

Under-construction commercial project combining professional office and retail space along Kissimmee’s W Irlo Bronson Memorial Hwy corridor.

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Retail Building with Shared Patio
Retail Building with Shared Patio

5086 Old Tampa Hwy 02, Kissimmee, FL 34758

$1,993,600
5,545 sqft

Shell-condition retail space offers a customizable interior and access to a shared outdoor patio.

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Two-Tenant Office Building
Two-Tenant Office Building

Saint Cloud, FL 34769

$600,000
2,346 sqft 0.17 AC lot

Downtown office property with leased occupancy, recent roof and AC improvements, and on-site parking.

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Established Convenience Store
Established Convenience Store

11 NEPTUNE Road, Kissimmee, FL 34744

$180,000
3,312 sqft 0.23 AC lot

Operating retail store positioned within Kissimmee’s downtown business district near multiple transit connections.

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Downtown Mixed-Use Building
Downtown Mixed-Use Building

12 E DARLINGTON Avenue, Kissimmee, FL 34741

$1,900,000
3,112 sqft 0.09 AC lot

Brick commercial building with central air on a visible corner site near downtown services, transit, and public parking.

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Freestanding Retail Building
Freestanding Retail Building

5034 Old Tampa Hwy 06, Kissimmee, FL 34758

$1,449,000
4,140 sqft

The single-story structure is planned for delivery in shell condition, allowing buyers to configure the interior.

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Waterfront Hotel and Café
Waterfront Hotel and Café

Saint Cloud, FL 34771

$2,850,000
6,430 sqft 1.13 AC lot

Four-building hospitality property with lake access, pavilion, and on-site kitchen facilities.

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Corner Commercial Land
Corner Commercial Land

Saint Cloud, FL 34769

$350,000
2,032 sqft 0.24 AC lot

A 0.24-acre corner parcel with an existing residence, pool, and alley access.

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Single-Level Office Building
Single-Level Office Building

1201 E OAK, Kissimmee, FL 34744

$5,000,000
15,000 sqft 2.00 AC lot

Flexible commercial building with open work areas, private rooms, multiple bathrooms, and substantial on-site parking.

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Flex Building with Grade-Level Bays
Flex Building with Grade-Level Bays

4411 TAMI Lane, Kissimmee, FL 34746

$3,250,000
1,600 sqft 2.54 AC lot

Office and warehouse space is paired with multiple grade-level bays for a range of industrial operations.

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Freestanding Storefront Building
Freestanding Storefront Building

820 N MAIN Street, Kissimmee, FL 34744

$520,000
1,530 sqft 0.10 AC lot

KB3-zoned commercial property with central air and flexible retail-oriented use potential.

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Restaurant Business with Equipment
Restaurant Business with Equipment

3815 W VINE STREET, Kissimmee, FL 34741

$600,000
4,807 sqft

An operating restaurant business is offered with its furnishings, equipment, inventory, and merchandise; the real estate is excluded.

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Mixed-Use Building with Office Units
Mixed-Use Building with Office Units

4560 W IRLO BRONSON MEMORIAL Highway, Kissimmee, FL 34746

$220,000
220 sqft 3.76 AC lot

New construction combines small-format office suites with dedicated retail space for professional and business users.

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Office Building with Secured Lease
Office Building with Secured Lease

Saint Cloud, FL 34769

$459,900
1,752 sqft 0.04 AC lot

Block-built commercial office asset with central HVAC, public utilities, and an in-place tenancy extending through February 2028.

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Flex Space with Warehouse Bays
Flex Space with Warehouse Bays

4411 Tami Ln, Kissimmee, FL 34746

$3,250,000
7,850 sqft 2.54 AC lot

Acreage, private offices, restrooms, and grade-level access support combined office and industrial operations.

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Office Units with Existing Lease
Office Units with Existing Lease

Saint Cloud, FL 34769

$459,900
1,742 sqft 0.04 AC lot

Office property with a tenant lease extending through December 2029 and public water and sewer service.

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Automotive Service Building with Lifts
Automotive Service Building with Lifts

2986 Michigan Ave, Kissimmee, FL 34744

$1,200,000
3,000 sqft

Four commercial-grade lifts are included, while the operating business is excluded from the sale.

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Office Unit with Lease in Place
Office Unit with Lease in Place

Saint Cloud, FL 34769

$459,900
1,727 sqft 0.04 AC lot

Existing tenancy extends through January 2028.

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Single-Story Mixed-Use Building
Single-Story Mixed-Use Building

5092 Old Tampa Hwy 01, Kissimmee, FL 34758

$1,456,000
4,181 sqft

The dark-gray shell can be finished for retail or office use and includes access to a shared patio.

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Renovated Office Building
Renovated Office Building

104 S CLYDE Avenue, Kissimmee, FL 34741

$564,000
1,887 sqft 0.34 AC lot

Flexible professional layout supports single-user occupancy or separate business suites with private entrances.

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Industrial Property with Covered Storage
Industrial Property with Covered Storage

Saint Cloud, FL 34773

$1,689,708
9,180 sqft 5.21 AC lot

Two grade-level buildings are complemented by controlled site access and outdoor storage.

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Full-Block Commercial Land
Full-Block Commercial Land

JOHN YOUNG PARKWAY, Kissimmee, FL 34741

$799,000
1.03 AC lot

T4-O zoning and a commercial future land use designation frame this downtown parcel’s development context.

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Osceola County, FL Commercial Real Estate Market Trends and Statistics

Explore 382 commercial real estate for sale in Osceola County, FL, showcased through 382 active listings on our real estate platform. These investment opportunities span a total of 1,027,790 square feet of properties for sale, with an estimated market value of $488,034,960.

Sale prices for business properties in Osceola County, FL start at $32,400, averaging $1,520,358, and reaching up to $15,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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