Mixed-Use

Lee County, FL Mixed-use Properties for Sale

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Cape Coral Mixed-Use Opportunity
Updated: Jun 30, 2025
Cape Coral Mixed-Use Opportunity

862 Lafayette St, Cape Coral, FL 33904

$2,970,000
17,564 sqft
Prime Downtown Cape Coral location in a vibrant district.
Over 17,500 sq ft, two‑story building with additional off‑street entrance and parking.
Equipped with 6 walk‑in coolers, 3 walk‑in freezers, 2 commercial kitchens, a butcher room, and phase‑3 power.
Includes two parcels: 862 Lafayette St. and 859 Miramar St.
High‑traffic location near Cape Coral Parkway and Coronado Parkway.
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862 Lafayette St, Cape Coral, FL

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Mixed-Use Property with Residential Units
Updated: Jun 3
Mixed-Use Property with Residential Units

2251 GRAND Avenue, Fort Myers, FL 33901

$1,200,000
4,688 sqft 0.15 AC lot
4,688‑square‑foot mixed‑use property with two residential condominium units and ground‑floor commercial space
Upstairs residences include a renovated 3‑bedroom, 2‑bath unit and a renovated 2‑bedroom, 2‑bath unit
Ground floor is configured as a music studio
Approximately 10 dedicated parking spaces in a fully fenced lot
CI zoning and block construction
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Shopping Center with Pylon Signage
Shopping Center with Pylon Signage

12709-12731 McGregor Blvd, Fort Myers, FL 33919

$4,970,000
3.72 AC lot

Neighborhood center with access from College Pkwy and McGregor Blvd, parking, landscaping, and a varied commercial tenant mix.

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Commercial Land with Development Plans
Commercial Land with Development Plans

1415 Cape Coral Parkway E, Cape Coral, FL 33904

$2,490,000
0.33 AC lot

Entitled site with plans for apartments, executive offices, and a ground-floor cafe in downtown Cape Coral.

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Renovated Commercial Property on Fowler Street
Renovated Commercial Property on Fowler Street

2730 Fowler Street, Fort Myers, FL 33901

$1,200,000
6,200 sqft 0.46 AC lot

Fully renovated commercial building with flexible space in Fort Myers.

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Mixed-Use Property with Lake Views
Mixed-Use Property with Lake Views

2430 Palm Ridge Road, Sanibel, FL 33957

$2,989,000
0.99 AC lot

Three buildings combine leased commercial suites with remodeled apartments and residential outlooks over the lake.

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Mixed-Use Building with 3 Apartments
Mixed-Use Building with 3 Apartments

1161 Estero Boulevard, Fort Myers Beach, FL 33931

$3,800,000
0.17 AC lot

Two-story property combines residential rentals with street-level commercial space in a pedestrian-oriented beach setting.

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Mixed-Use Property with Two Condos
Mixed-Use Property with Two Condos

2251 Grand Avenue, Fort Myers, FL 33901

$1,999,999
0.15 AC lot

Renovated residential units occupy the upper level above a flexible ground-floor commercial studio.

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Mixed-Use Building with Storage
Mixed-Use Building with Storage

5261 Pine Island Rd, Bokeelia, FL 33922

$1,295,000
5,184 sqft 0.62 AC lot

Remodeled office and retail units with supplemental storage structures and commercial zoning on Pine Island.

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Gulfside Commercial Land
Gulfside Commercial Land

2096 ESTERO Boulevard, Fort Myers Beach, FL 33931

$3,349,000
0.40 AC lot

Commercial land on Estero Boulevard with public water and sewer service.

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Mixed-Use Duplex with Commercial Space
Mixed-Use Duplex with Commercial Space

2826 Santa Barbara Boulevard, Cape Coral, FL 33914

$460,000
0.23 AC lot

MR zoning supports a combined commercial and residential configuration with public utilities and fenced grounds.

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Mixed-Use Duplex with Commercial Space
Mixed-Use Duplex with Commercial Space

2826 Santa Barbara Boulevard, Cape Coral, FL 33914

$460,000
2,406 sqft

MR zoning supports a live-work arrangement with commercial and residential components.

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Market Place Residential Land
Market Place Residential Land

1626 NW 2nd Avenue, Cape Coral, FL 33993

$1,749,900
5.18 AC lot

Commercial land in Cape Coral’s Market Place Residential District supports retail, office, service, residential, and mixed-use development concepts.

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Two-Level Office Building
Two-Level Office Building

905 Fitzhugh Street, Sanibel, FL 33957

$1,095,000
0.26 AC lot

Commercial building with an open lower level and flexible upper-floor configuration in Town Center Limited zoning.

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Commercial Sale
Commercial Sale

1165-1161 Estero Blvd, Fort Myers Beach, FL 33931

$4,200,000
5,568 sqft 0.16 AC lot

Mixed-use properties · 5,568 SF

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Waterfront Commercial Land
Waterfront Commercial Land

1223 Periwinkle Way, Sanibel, FL 33957

$2,999,000
2.29 AC lot

General Commercial and D2 Upland Wetland zoning supports commercial or mixed-use redevelopment concepts.

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Gulf-Front Waterfront Land
Gulf-Front Waterfront Land

800-802 Estero Boulevard, Fort Myers Beach, FL 33931

$15,500,000
1.58 AC lot

Beachfront acreage with direct shoreline access and proximity to Fort Myers Beach’s Times Square district and pier.

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Turn-Key Showroom and Office Building
Turn-Key Showroom and Office Building

3327 Railroad St, Fort Myers, FL 33916

Contact for pricing
8,240 sqft 0.81 AC lot

Showroom and office building with storage near downtown Fort Myers.

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Prime Mixed-Use Development Opportunity
Prime Mixed-Use Development Opportunity

2915 Estero Boulevard, Fort Myers Beach, FL 33931

$1,095,000
0.11 AC lot

Cleared lot on Estero Blvd, steps from the Gulf.

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Profitable Fort Myers Investment Opportunity
Profitable Fort Myers Investment Opportunity

3775 Fowler ST, Fort Myers, FL 33901

$2,025,000
12,778 sqft 0.99 AC lot

Well-maintained, fully leased mixed-use building with long-term tenants.

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Downtown Fort Myers Commercial Property
Downtown Fort Myers Commercial Property

1782 Fowler Street, Fort Myers, FL 33901

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18,428 sqft

Highly visible property in a Southwest Florida commercial corridor.

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Corner Showroom/Retail/Office/Warehouse Space
Corner Showroom/Retail/Office/Warehouse Space

28360 Old 41 Rd 11, Bonita Springs, FL 34135

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2,123 sqft

Corner unit suitable for showroom, retail, office, or warehouse.

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Mixed-Use Development Opportunity in Cape Coral
Mixed-Use Development Opportunity in Cape Coral

1130 NE 7th Terrace, Cape Coral, FL 33909

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56,344 sqft 1.83 AC lot

Approved mixed-use development site with residential and commercial space.

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Two-Unit Gateway Building For Sale
Two-Unit Gateway Building For Sale

12221 Towne Lake Dr, Fort Myers, FL 33913

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5,000 sqft

Two-unit building with long-term tenants, warehouse, and office space.

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Lee County, FL Mixed-Use Properties Market Trends and Statistics

Explore 72 mixed-use properties for sale in Lee County, FL, showcased through 39 active listings on our real estate platform. These investment opportunities span a total of 324,794 square feet of properties for sale, with an estimated market value of $76,923,898.

Sale prices for multi use buildings in Lee County, FL start at $460,000, averaging $3,076,955, and reaching up to $15,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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