Monroe County, FL Commercial real estate for sale

Updated: Aug 28

Mixed-Use Property with Work Areas

5670 Laurel Avenue, Stock Island, FL 33040

$1,749,000

5,258 sqft 0.29 AC lot

Two 50' x 125' lots totaling 0.29 acres
5,258‑square‑foot ground‑level CBS building constructed in 1980
100 feet of frontage and 125 feet of depth on Laurel Avenue
Covered and outdoor work areas with off‑street parking
MU - Mixed Use District zoning

View details

Updated: Sep 1

Highway-Front Office Building

98251 Overseas Highway, Key Largo, FL 33037

$899,000

2,188 sqft 0.64 AC lot

2,188‑square‑foot office building on a 27,790‑square‑foot lot
130 feet of frontage along Overseas Highway
0.64‑acre site with parking and shaded areas
Four rooms, two bathrooms, and four exterior entrances
Established access easement off Coco Plum Road

View details

Mixed-Use Building with Apartment

22814 Overseas Highway, Cudjoe Key, FL 33042

$875,000

1,120 sqft 0.19 AC lot

The property pairs office space with a two-bedroom residence, with existing tenants in both areas.

View details

Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads

High-Frontage Mixed-Use Building with Suites

92295 Old State Road, #4A, Key Largo, FL 33070

$2,850,000

6,214 sqft 0.86 AC lot

Concrete mixed-use building with six exterior-access suites and extensive US-1 frontage for flexible retail, office, and medical use.

View details

Six-Suite Mixed-Use Building

92295 Old State Road, Key Largo, FL 33070

$2,850,000

6,241 sqft 0.86 AC lot

Fenced commercial property with flexible suites, exterior access, central air, and SC - Sub Urban Commercial zoning.

View details

Mixed-Use Property with Six Storefronts

218 Whitehead Street, Key West, FL 33040

$4,200,000

7,755 sqft 0.16 AC lot

Corner property combines six retail spaces with a three-bedroom, two-bath apartment and separate utility meters.

View details

Five-Office Commercial Unit

1421 First Street, Key West, FL 33040

$599,000

1,160 sqft 0.06 AC lot

Professional office configuration includes a restroom within CL - Limited Commercial zoning.

View details

Three-Story Restaurant Building

82779 Overseas Hwy, Islamorada, FL 33036

$3,999,000

5,421 sqft 0.34 AC lot

Restaurant improvements include a fitted kitchen, two bars, two dining rooms, and dedicated management space.

View details

Single-Story Office Building

701 Simonton Street, Key West, FL 33040

$1,850,000

1,745 sqft 0.15 AC lot

Corner commercial property with five private offices, reception space, storage, and off-street parking.

View details

Mixed-Use Commercial Land

5331 5th Avenue, Stock Island, FL 33040

$2,050,000

5,705 sqft 0.69 AC lot

The site carries MU zoning and includes seven electric meters and seven water meters.

View details

Highway-Frontage Office Building

98251 Overseas Highway, Key Largo, FL 33037

$899,000

2,188 sqft 0.64 AC lot

Flexible commercial layout with multiple entrances, reception space, private rooms, and two bathrooms.

View details

Three-Unit Mixed-Use Property

1200-1206 White Street, Key West, FL 33040

$1,475,000

3,380 sqft

Commercial condominium offering with established occupants, one vacant unit, and flexible office, retail, service, and restaurant use potential.

View details

End-Unit Storefront Condo

1206 White Street, Key West, FL 33040

$575,000

1,389 sqft

Commercial condominium with central air, one assigned parking space, and hurricane-rated windows and doors.

View details

Two-Story Office Building

90184 Overseas Highway, Plantation Key, FL 33070

$4,500,000

6,560 sqft

Commercial office property with corner positioning and direct access along U.S. Highway 1.

View details

Updated Corner Office Unit

1200 White Street, Key West, FL 33040

$530,000

1,169 sqft

First-floor commercial condo with impact-rated windows, assigned parking, and an existing tenant in place.

View details

Waterfront Marina Building

90515 Old Highway, Plantation Key, FL 33070

$1,750,000

1,584 sqft 0.18 AC lot

Village Center-zoned commercial property with boat slips, existing leases, and direct ocean access without bridge crossings.

View details

Auto Shop with Covered Work Areas

5670 Laurel Avenue, Stock Island, FL 33040

$1,749,000

5,258 sqft 0.29 AC lot

Mixed-use zoning supports commercial and residential uses, with licenses covering repair, towing, detailing, rentals, and retail sales.

View details

Concrete Office Building with Showroom

88701 Overseas Highway, Plantation Key, FL 33070

$2,400,000

1,957 sqft 0.28 AC lot

Two-level commercial property with office areas, product display space, parking, and General Commercial zoning.

View details

Concrete Office Building with Showroom

88701 Overseas Highway, Plantation Key, FL 33070

$2,400,000

1,957 sqft 0.28 AC lot

Professionally built office property with impact windows and interior showroom space plus ample on-site parking.

View details

Bicycle Retail Space with Showroom

21 County Road, Big Pine Key, FL 33043

$179,000

3,240 sqft 0.28 AC lot

Retail property with a showroom, bicycle repair center, and assumable lease.

View details

Renovated Retail Space with Patio

19980 Overseas Highway, Sugarloaf Key, FL 33042

$1,950,000

2,520 sqft 0.71 AC lot

Completely renovated retail property on US-1 with private offices, refreshed restrooms, and a spacious outdoor patio.

View details

Concrete Mixed-Use Building

100636 Overseas Highway, Key Largo, FL 33037

$1,790,000

4,910 sqft 0.18 AC lot

Ground-floor commercial space is paired with a renovated three-bedroom, three-bath apartment and rooftop, patio, and yard areas.

View details

Fenced Mixed-Use Commercial Building

4a-92295 Old State Rd, Key Largo, FL 33037

$2,850,000

6,214 sqft 0.86 AC lot

Concrete commercial property with multiple suites, highway frontage, and access serving both directions of US-1.

View details

Storefront Retail Condo

1202 White Street, Key West, FL 33040

$445,000

892 sqft

In-place tenancy, assigned parking, and historic neighborhood commercial zoning add practical flexibility for a commercial user.

View details

Monroe County, FL Commercial Real Estate Market Trends and Statistics

Explore 269 commercial real estate for sale in Monroe County, FL, showcased through 269 active listings on our real estate platform. These investment opportunities span a total of 430,971 square feet of properties for sale, with an estimated market value of $602,212,623.

Sale prices for business properties in Monroe County, FL start at $35,000, averaging $2,712,669, and reaching up to $20,350,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.