Monroe County, FL Commercial Real Estate for Sale

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End-Unit Commercial Condo
Updated: Jul 1
End-Unit Commercial Condo

1206 White Street, Key West, FL 33040

$599,000
1,389 sqft
Commercial condo with over 1,300 SF, end unit, centrally located in Old Town
Office space in back can be rented separately for additional income
Half bath plus bathroom 1; central air cooling
Hurricane‑rated windows and doors; CBS/combo construction; built in 1989
One assigned off‑street parking spot
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1206 White Street, Key West, FL 33040

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Prime US-1 Mixed-Use Opportunity
Updated: Apr 13
Prime US-1 Mixed-Use Opportunity

92295 Old State Road, Key Largo, FL 33070

$2,895,000
6,241 sqft 0.86 AC lot
Prime US‑1 highway frontage (313 feet) in Tavernier with high visibility and traffic.
Mixed‑use commercial building with approximately 6,214 sq. ft. of space.
Six separate units/suites, providing flexibility for multiple tenants or diverse business operations.
Located on the northbound side of US‑1 with convenient access to the southbound lane.
Suitable for various uses: retail, office, medical, educational, fitness, or storage.
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Bicycle Retail and Repair Shop
Bicycle Retail and Repair Shop

21 County Road, Big Pine Key, FL 33043

$179,000
3,240 sqft 0.28 AC lot

Retail showroom with rentals and a full-service repair center, with new inventory and equipment included in the sale.

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Mixed-Use Development Land
Mixed-Use Development Land

5331 5th Avenue, Stock Island, FL 33040

$2,150,000
5,705 sqft 0.69 AC lot

Four-parcel site in MU zoning with multiple electric and water meters for redevelopment in Stock Island, FL.

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81901 Overseas Hwy, Islamorada, FL, 33036-3647
81901 Overseas Hwy, Islamorada, FL, 33036-3647

81901 Overseas Hwy, Islamorada, FL 33036

$2,200,000
4,942 sqft 0.38 AC lot

Iconic restaurant property with high visibility and flexible commercial zoning.

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Single-Story Office Building
Single-Story Office Building

701 Simonton Street, Key West, FL 33040

$1,850,000
1,745 sqft 0.15 AC lot

Single-story office building with five private offices, central A/C, and multiple off-street parking spaces on a corner lot.

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Flex Space Corner Parcel with Fencing
Flex Space Corner Parcel with Fencing

104980 Overseas Highway, Key Largo, FL 33037

$1,200,000
1,024 sqft 0.37 AC lot

Ground-level concrete flex building with high ceilings, central A/C, and access from front and back.

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Marathon Commercial Property For Sale
Marathon Commercial Property For Sale

11401 Overseas Highway, Marathon, FL 33050

$1,533,333
3,429 sqft 0.34 AC lot

Commercial building with highway exposure and ample parking in Marathon.

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High-Frontage Mixed-Use Building with Suites
High-Frontage Mixed-Use Building with Suites

92295 Old State Road, #4A, Key Largo, FL 33070

$2,895,000
6,214 sqft 0.86 AC lot

Concrete mixed-use building with six exterior-access suites and extensive US-1 frontage for flexible retail, office, and medical use.

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Multi-Unit Commercial Condo Building
Multi-Unit Commercial Condo Building

1200-1206 White Street, Key West, FL 33040

$1,599,000
3,380 sqft

Three retail and office condo units in an X flood zone, including one vacant space for immediate use or lease.

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High-Visibility Commercial Property in Big Pine
High-Visibility Commercial Property in Big Pine

30330 - 30348 Overseas Highway, Big Pine Key, FL 33043

$3,100,000
5,250 sqft 0.81 AC lot

Prime commercial property with high traffic and income potential.

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Office Condo with Private Balcony
Office Condo with Private Balcony

1010 Kennedy Drive, #307, Key West, FL 33040

$349,000
2,058 sqft

3rd-floor office condo with two entrances, an open layout, kitchenette, and a private balcony for client-ready workflow.

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Prime Corner Commercial Property, Key West
Prime Corner Commercial Property, Key West

1000 Truman Avenue, Key West, FL 33040

$2,699,000
2,396 sqft 0.27 AC lot

Corner property with high visibility, multiple commercial uses allowed.

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New Mixed-Use Development in Key West
New Mixed-Use Development in Key West

3201 Flagler Avenue, Key West, FL 33040

$749,000
1,491 sqft 0.71 AC lot

Commercial space in new mixed-use development, completion end of 2026.

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Concrete Office Building with Showroom
Concrete Office Building with Showroom

88701 Overseas Highway, Plantation Key, FL 33070

$2,400,000
1,957 sqft 0.28 AC lot

Professionally built office property with impact windows and interior showroom space plus ample on-site parking.

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Leased Office/Retail Condo
Leased Office/Retail Condo

1075 Duval Street, Key West, FL 33040

$499,000
648 sqft

Fully leased office/retail condo on Duval Street with recent upgrades including new AC, storefront windows, and impact-rated entrance.

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Key Largo Mixed-Use Property
Key Largo Mixed-Use Property

100636 Overseas Highway, Key Largo, FL 33037

$1,790,000
4,910 sqft 0.18 AC lot

High-visibility mixed-use property with commercial storefront and residential apartment.

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Hurricane-Rated Retail/Office Condo
Hurricane-Rated Retail/Office Condo

1202 White Street, Key West, FL 33040

$499,000
892 sqft

Centrally located 892sf condo with hurricane-rated windows and doors, one assigned parking spot, and X Flood Zone designation.

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Turnkey Retail Condominium Suite
Turnkey Retail Condominium Suite

1012 Truman Avenue, Key West, FL 33040

$439,000
718 sqft 3,490.99 AC lot

Turnkey retail condo with updated flooring and paint, plus HOA coverage for building and common area maintenance.

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200 Treasure Harbor Dr, Islamorada, FL, 33036-3136
200 Treasure Harbor Dr, Islamorada, FL, 33036-3136

200 Treasure Harbor Dr, Islamorada, FL 33036

$6,995,000
1,219 sqft 1.09 AC lot

Unique Marina and Resort with Deep Water Harbor and Amenities.

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Updated Corner Commercial Condo
Updated Corner Commercial Condo

1200 White Street, Key West, FL 33040

$599,000
1,169 sqft

First-floor corner unit with hurricane-rated impact windows and tenant in place, suited for retail or professional services.

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Mixed-Use Auto Service Building
Mixed-Use Auto Service Building

5670 Laurel Avenue, Stock Island, FL 33040

$1,950,000
5,258 sqft

CBS auto service building on two combined lots with covered and outdoor work areas and mixed-use zoning.

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Stock Island Commercial Property For Sale
Stock Island Commercial Property For Sale

5670 Laurel Ave, Key West, FL 33040

$1,950,000
5,258 sqft 0.29 AC lot

Commercial property on Stock Island with mixed-use zoning.

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Concrete Commercial Building with Impact Windows
Concrete Commercial Building with Impact Windows

88701 Overseas Highway, Plantation Key, FL 33070

$2,400,000
1,957 sqft 0.28 AC lot

Solid concrete commercial building with impact windows and doors, zoned CG - General Commercial with ample parking.

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Monroe County, FL Commercial Real Estate Market Trends and Statistics

Explore 231 commercial real estate for sale in Monroe County, FL, showcased through 231 active listings on our real estate platform. These investment opportunities span a total of 402,208 square feet of properties for sale, with an estimated market value of $357,466,729.

Sale prices for business properties in Monroe County, FL start at $149,000, averaging $3,470,550, and reaching up to $30,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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