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Lee County, FL Office Properties & Spaces for Lease

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258 results
Medical Office Space For Rent
$3,250 /Mo

Medical Office Space For Rent

13195 Metro Parkway, Fort Myers, FL 33966

Located in a rapidly expanding healthcare corridor in Fort Myers.

  • Strategic location within a rapidly expanding healthcare corridor in Fort Myers.
  • Close proximity to multiple Lee Health facilities, including the newly constructed hospital campus and Gulf Coast Medical Center.
  • Ideally suited for medical, wellness, and service‑oriented users.
  • High concentration of physician offices, outpatient services, and medical businesses in the surrounding area.
  • Direct access to key roadways such as Colonial Boulevard and Daniels Parkway.
Updated: Apr 7
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Cape Coral Office Space Available
$1,975 /Mo

Cape Coral Office Space Available

4020 Del Prado Boulevard S, Cape Coral, FL 33904

Professional office space for rent in Cape Coral, Florida.

  • Located at the signalized intersection of Del Prado Blvd. and Coronado Pkwy, offering excellent exposure and easy access.
  • Available within 7 days.
  • Open floor plan with two private offices, storage closet, and restroom.
  • Visually attractive multi‑tenant professional office building and grounds.
  • Rental rate includes CAM.
Updated: Mar 25
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Well-Maintained Office Suite For Rent
$1,550 /Mo

Well-Maintained Office Suite For Rent

Office suite with private offices and shared conference room.

3403 Hancock Bridge Parkway, North Fort Myers, FL 33903
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Cape Coral First Floor Office
$2,250 /Mo

Cape Coral First Floor Office

883 SF office space available in April 2026.

923 Del Prado Boulevard S, Cape Coral, FL 33990
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Cape Coral Commercial Office Space
$2,500 /Mo

Cape Coral Commercial Office Space

Multi-tenant office building with warehouse space available for rent.

4427 SE 16th Place, Cape Coral, FL 33904
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Cape Coral Industrial Building For Rent
$4,150 /Mo

Cape Coral Industrial Building For Rent

Industrial building with office and warehouse space available for rent.

954 Country Club Boulevard, Cape Coral, FL 33990
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Cape Coral Executive Office Suite
$1,700 /Mo

Cape Coral Executive Office Suite

Move-in ready office space near City Hall with flexible layout.

1212 Country Club Boulevard, Cape Coral, FL 33990
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Luxury Office in Coconut Point
$21 SF/Yr

Luxury Office in Coconut Point

Upscale office space in a vibrant mixed-use destination.

23190 Fashion Drive, Estero, FL 33928
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Fort Myers Commercial Flex Space
$17 SF/Yr

Fort Myers Commercial Flex Space

3,000 SF flex space available for lease in Fort Myers.

1687 Benchmark Avenue, Fort Myers, FL 33905
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Fort Myers Beach Retail/Office Space
$21 SF/Yr

Fort Myers Beach Retail/Office Space

1420 RSF suite with high visibility on Estero Boulevard.

6035 Estero Boulevard, Fort Myers Beach, FL 33931
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Cape Coral Commercial Space Available
$2,950 /Mo

Cape Coral Commercial Space Available

Air-conditioned office and warehouse space in downtown Cape Coral.

4519 SE 16th Place, Cape Coral, FL 33904
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Warehouse with Office Space Available
$1,900 /Mo

Warehouse with Office Space Available

Warehouse space with office in North Cape Industrial Park.

909 NE 27th Lane, Cape Coral, FL 33909
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Cape Coral Warehouse with Office
$2,100 /Mo

Cape Coral Warehouse with Office

Warehouse space with office in North Cape Industrial Park.

909 NE 27th Lane, Cape Coral, FL 33909
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Downtown Cape Coral Office Space
$1,000 /Mo

Downtown Cape Coral Office Space

Spacious office space in the heart of downtown Cape Coral.

4705 Vincennes Boulevard, Cape Coral, FL 33904
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Cape Coral Office/Medical Space
$18 SF/Yr

Cape Coral Office/Medical Space

Recently remodeled office space suitable for medical or professional use.

1224 Del Prado Boulevard S, Cape Coral, FL 33990
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Modern Furnished Office Spaces Available
$2,000 /Mo

Modern Furnished Office Spaces Available

Two furnished office spaces for rent with included amenities.

3850 Colonial Boulevard, Fort Myers, FL 33966
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Cape Coral Office Space For Rent
$2,895 /Mo

Cape Coral Office Space For Rent

Approximately 1000 SF end unit in great location.

3046 Del Prado Boulevard S, Cape Coral, FL 33904
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New Retail Space in Fort Myers
$25 SF/Yr

New Retail Space in Fort Myers

Modern retail units in a high-growth Southwest Florida corridor.

8156 Alico Rd, Fort Myers, FL 33912
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New Retail Space in Fort Myers
$35 SF/Yr

New Retail Space in Fort Myers

Modern retail units in a high-growth area with excellent visibility.

8156 Alico Rd, Fort Myers, FL 33912
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Fort Myers Office/Salon Suites
$12 SF/Yr

Fort Myers Office/Salon Suites

1,400 sq ft office/salon suites available for rent.

3949 Evans Avenue, Fort Myers, FL 33901
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Cape Coral Freestanding Retail/Office Building
Contact for pricing

Cape Coral Freestanding Retail/Office Building

Freestanding building in booming Cape Coral with pylon signage.

1329 Hibiscus Drive, Cape Coral, FL 33909
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Downtown Cape Coral Office Space
Contact for pricing

Downtown Cape Coral Office Space

Professional office suite in a high-visibility downtown location.

1314 Cape Coral Parkway E, Cape Coral, FL 33904
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Cape Coral Commercial Office Space
$1,600 /Mo

Cape Coral Commercial Office Space

Commercial unit in Cape Coral, ideal for office space.

1211 Miramar Street, Cape Coral, FL 33904
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Cape Coral Commercial Office Space
$1,600 /Mo

Cape Coral Commercial Office Space

Commercial unit in Cape Coral, suitable for office space.

1211 Miramar Street, Cape Coral, FL 33904
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Lee County, FL Office properties & Spaces Leasing Opportunities Market Analysis

Explore Office properties & Spaces leasing options in Lee County, FL with 258 listings featured on our commercial real estate exchange. The current inventory includes 171,901,473,775 square feet of properties with an estimated lease value of $971 /Mo.

Estimated lease rates for Office properties & Spaces in Lee County, FL begin at $0.91 SF/Yr, with an average of $16 SF/Yr and extend to $75 SF/Yr.
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