For Sale
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Property Types
  • Retail
  • Office
  • Residential Income
  • Restaurants
  • Industrial
  • Mixed-Use
  • Hospitality
  • Health Care
  • Sports & Entertainment
  • Land
  • Agricultural
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Lee County, FL Commercial Real Estate for Sale

8,640 results
List
Map
Cape Coral Commercial Development Opportunity
Pending
$269,000
0.61 Acres

Cape Coral Commercial Development Opportunity

1808 Skyline Blvd, Cape Coral, FL 33991

Commercial development opportunity with mixed-use potential in a rapidly growing area.

  • Exceptional development opportunity in rapidly growing Cape Coral corridor.
  • Mixed‑use project with approved plans for 7,470 SF structure (office, warehouse, retail).
  • Zoning CI/CP permits a variety of high‑demand commercial uses.
  • Includes complete mechanical, electrical, and plumbing plans.
  • 26,744 SF site with 19 parking spaces (including ADA).
Updated: Jan 17
View details
Versatile Garage in Commercial Complex
Pending
$425,000
0.02 Acres

Versatile Garage in Commercial Complex

12321 Itec Park Dr, Fort Myers, FL 33913

Well-maintained garage suitable for automotive, retail, flex, or industrial use.

  • Mezzanine plumbed for kitchen/bar offers customization for workspace or leisure.
  • High ceilings and roll‑up bay door provide easy vehicle access.
  • Full bathroom with shower adds convenience.
  • Durable epoxy flooring withstands heavy‑duty use.
  • Large storage closet under stairs maximizes organization.
Updated: Jan 14
View details
Bonita Springs Commercial Opportunity
$1,200,000
2,506 SF

Bonita Springs Commercial Opportunity

Two buildings on US 41 in Bonita Springs.

27831 S Tamiami Trl, Bonita Springs, FL 34134
View details
Freestanding Commercial Building For Sale
$107,000
2,000 SF

Freestanding Commercial Building For Sale

High-visibility commercial building suitable for restaurants, retail, or event spaces.

2847 Cleveland Ave, Fort Myers, FL 33901
View details
Cape Coral Retail Investment Property
$1,050,000
0.14 Acres

Cape Coral Retail Investment Property

Retail property in desirable downtown Cape Coral location with tenants.

1336 Cape Coral Pkwy E, Cape Coral, FL 33904
View details
Remodeled Office & Warehouse Condo
Pending
$224,900
0.05 Acres

Remodeled Office & Warehouse Condo

Remodeled commercial condo with office and warehouse space in Fort Myers.

2235 Bruner Ln, Fort Myers, FL 33912
View details
Cape Coral Two-Story Commercial Building
$1,350,000
5,920 SF

Cape Coral Two-Story Commercial Building

Two-story commercial building in downtown Cape Coral with owner financing.

1313 SE 47Th Ter, Cape Coral, FL 33904
View details
Historic Sanibel Building in Prime Location
$1,500,000
0.43 Acres

Historic Sanibel Building in Prime Location

Iconic Sanibel building, reimagined for modern use in high-traffic location.

520 Tarpon Bay Rd, Sanibel, FL 33957
View details
Mixed-Use Development Site with Plans
$28,750,000
0.33 Acres

Mixed-Use Development Site with Plans

Mixed-use development site with approved plans in downtown Cape Coral.

1415 Cape Coral Pkwy E, Cape Coral, FL 33904
View details
Matlacha Restaurant and Marina Property
Pending
$3,300,000
1.41 Acres

Matlacha Restaurant and Marina Property

Unique restaurant and marina property in the heart of Matlacha.

4520 Pine Island Rd NW, Matlacha, FL 33993
View details
Gulf Access Multi-Tenant Office Building
$5,900,000
1.12 Acres

Gulf Access Multi-Tenant Office Building

Two-story office building with Gulf access on a signalized corner.

2804 Del Prado Blvd S, Cape Coral, FL 33904
View details
Historic Matlacha Corner Retail Opportunity
Pending
$599,900
0.11 Acres

Historic Matlacha Corner Retail Opportunity

High-traffic corner property in historic Matlacha, ideal for retail.

4573 Pine Island Rd NW, Matlacha, FL 33993
View details
Bonita Springs Professional/Medical Office Space
Pending
Contact for pricing
0.12 Acres

Bonita Springs Professional/Medical Office Space

Modern office suites available for lease in a visible Bonita Springs location.

10971 Bonita Beach Rd SE, Bonita Springs, FL 34135
View details
Bonita Springs Office Space Available
Contact for pricing
4.69 Acres

Bonita Springs Office Space Available

Third-floor office space in Bonita Bay Club Lifestyle Center.

26800 S Tamiami Trl, Bonita Springs, FL 34134
View details
Updated Office Condo For Sale
$245,000
0.27 Acres

Updated Office Condo For Sale

Professionally updated office condo in central Fort Myers location.

3949 Evans Ave, Fort Myers, FL 33901
View details
Fort Myers Commercial Building For Sale
$550,000
0.34 Acres

Fort Myers Commercial Building For Sale

Commercial building with office, garage, and covered parking available.

3018 Cleveland Ave, Fort Myers, FL 33901
View details
Luxury Storage Unit in Fort Myers
$210,000
0.01 Acres

Luxury Storage Unit in Fort Myers

Immaculate storage unit ideal for vehicle, RV, or boat storage.

17860 Toy Vault Ln, Fort Myers, FL 33967
View details
Profitable Commercial Building in Fort Myers
$2,025,000
0.97 Acres

Profitable Commercial Building in Fort Myers

Well-maintained, fully leased commercial building with diverse tenants and ample parking.

3775 Fowler St, Fort Myers, FL 33901
View details
Gateway to Fort Myers Beach
$1,495,000
0.19 Acres

Gateway to Fort Myers Beach

High-traffic corner property with drive-through and ample parking.

19003 San Carlos Blvd, Fort Myers Beach, FL 33931
View details
Luxury Storage Condo in Fort Myers
$454,900
0.04 Acres

Luxury Storage Condo in Fort Myers

Premier storage condo with high-end finishes and 24/7 security.

17821 Toy Vault Ln, Fort Myers, FL 33967
View details
Drive-Through Garage Condo in Alico
$650,000
0.44 Acres

Drive-Through Garage Condo in Alico

Rare double garage condo with auto lifts for sale.

12300 Itec Park Dr, Fort Myers, FL 33913
View details
Fort Myers Commercial Office Space
Contact for pricing
0.18 Acres

Fort Myers Commercial Office Space

Office/medical space with flexible floorplan in well-maintained business center.

13411 Parker Commons Blvd, Fort Myers, FL 33912
View details
Fort Myers Office/Medical Park
Contact for pricing
5.17 Acres

Fort Myers Office/Medical Park

Centrally located office/medical park with immediate occupancy and ample parking.

6831 Palisades Park Ct, Fort Myers, FL 33912
View details
Fort Myers Industrial Property Available
Contact for pricing
8.59 Acres

Fort Myers Industrial Property Available

Industrial property available in Fort Myers, ready September 1, 2025.

4000-4051 Warehouse Rd, Fort Myers, FL 33916
View details

Lee County, FL Commercial Real Estate Investment Opportunities Market Analysis

Explore 5000+ commercial real estate investment opportunities in Lee County, FL with 5000+ listings featured on our commercial real estate marketplace. The current inventory includes 1,909,235,210 square feet of properties with an estimated value of $8,482,060,290.

Estimated prices for commercial real estate in Lee County, FL begin at $30,000, with an average of $704,958 and extend to $30,000,000.

In Lee County, FL, current investment values show:

  • Land positioned at $306,245
  • Residential land & home lots measuring $190,117
  • Office Properties & Spaces assessed at $863,039
  • Industrial properties calculated at $872,310
List
Map