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    Berkeley County, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    176 results
    Historic Charleston Mixed-Use Building
    $2,650,000
    4,923 SF

    Historic Charleston Mixed-Use Building

    59 Broad Street, Charleston, SC 29401

    Three-story mixed-use building in Charleston's historic commercial corridor.

    • Prime location on Broad Street in Charleston's historic commercial corridor
    • Approved entitlements for food & beverage use
    • Permit‑ready storefront renovation with accordion doors and updated facade
    • Approved addition of an 820 sq ft fourth‑floor penthouse
    • Mixed‑use building offering flexibility for owner‑occupancy or investment
    Updated: Mar 31
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    Retail Redevelopment Opportunity
    $825,000
    7,029 SF

    Retail Redevelopment Opportunity

    1831 Reynolds Ave, 1824 & 1828 Dayton Street, Charleston, SC 29405

    Opportunity Zone property with a 7,029 SF retail building and additional residential lot, offering flexible redevelopment potential.

    • 7,029 SF building for sale, currently known as Shorty’s Novelties & Snack Bar
    • Building located in an Opportunity Zone (TMS #s: 469‑12‑00‑022, 023, 048, 050)
    • Total site consists of 3 parcels totaling 0.47 AC
    • Includes an additional 0.19 AC R‑1 lot at 1824 Dayton Street
    • Zoning totals: B2—0.47 AC and R‑1—0.19 AC
    Updated: Jun 2
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    Charleston Land Package For Sale
    $3,500,000
    0.36 Acres

    Charleston Land Package For Sale

    Two adjoining lots totaling approximately .36 acres in Charleston, SC.

    148 President Street, Charleston, SC 29403
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    Warehouse Office with Drive-In Access
    $625,000
    2,520 SF

    Warehouse Office with Drive-In Access

    Small warehouse-office set up for light industrial or service use, featuring drive-in and dock-high loading with on-site restroom.

    806 Elsey Dr, Charleston, SC 29407
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    Charleston Medical Property Investment
    $1,895,000

    Charleston Medical Property Investment

    Thriving medical property in Charleston, SC with favorable lease terms.

    2039 Savannah Highway, Charleston, SC 29407
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    Moncks Corner Land For Sale
    $1,500,000
    18.00 Acres

    Moncks Corner Land For Sale

    21+/- acres in growing industrial corridor, Moncks Corner, SC.

    Mount Pleasant Drive, Moncks Corner, SC 29461
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    New Commercial Facility on 5 Acres
    $1,750,000
    8,825 SF

    New Commercial Facility on 5 Acres

    New 8,825 SF facility on 5 acres in Moncks Corner.

    2350 Cooper Store Rd, Moncks Corner, SC 29461
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    Bonneau Commercial Parcel For Sale
    $275,000
    1.00 Acre

    Bonneau Commercial Parcel For Sale

    One-acre commercial parcel in growing Bonneau, SC.

    1042 Bethera Road, Bonneau, SC 29431
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    Cleared Lot on Highway 17-A
    $200,000
    0.47 Acres

    Cleared Lot on Highway 17-A

    Cleared 0.47 acre lot with road frontage in Moncks Corner.

    231 S Live Oak Drive, Moncks Corner, SC 29461
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    Prime West Ashley Acreage Opportunity
    $999,000
    2.37 Acres

    Prime West Ashley Acreage Opportunity

    2.37 acres in West Ashley, ideal for development.

    736 Savage Road, Charleston, SC 29414
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    Daniel Island Deepwater Residential Opportunity
    $5,500,000
    1.66 Acres

    Daniel Island Deepwater Residential Opportunity

    Rare waterfront acreage ideal for residential or commercial development.

    1995 Daniel Island Drive, Charleston, SC 29492
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    Redevelopment Service Garage Site
    $4,200,000
    9,516 SF

    Redevelopment Service Garage Site

    A General Business-zoned opportunity zone parcel with an on-site service garage and utilities ready for redevelopment.

    1822 Meeting Street Road, Charleston, SC 29405
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    Flex Building with Roll-Up Doors
    $3,200,000
    8,000 SF

    Flex Building with Roll-Up Doors

    Renovated flex building on a cleared lot with high ceilings, brick accents, and 40 parking spaces.

    2910 Rivers Avenue, Charleston, SC 29405
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    Free-Standing Office Building
    $895,000
    5,000 SF

    Free-Standing Office Building

    A flexible office layout offers private offices, open bullpen space, and exam-ready rooms for medical or legal use.

    4476 Leeds Place West, Charleston, SC 29405
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    2.37 Acres in Wando, SC
    $1,550,000
    2.37 Acres

    2.37 Acres in Wando, SC

    2.37 acres of commercial land with easy highway access.

    Clements Ferry Road, Wando, SC 29492
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    Charleston Multifamily Bed and Breakfast
    $3,197,000
    6,025 SF

    Charleston Multifamily Bed and Breakfast

    Five-unit bed and breakfast in Charleston's Short-Term Rental Overlay.

    194-196 Rutledge Avenue, Charleston, SC 29403
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    Savannah Highway Commercial Land Parcel
    $700,000
    5.35 Acres

    Savannah Highway Commercial Land Parcel

    5.35 acre commercial land parcel on Savannah Highway.

    3300 Savannah Highway, Charleston, SC 29414
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    Downtown Charleston Corner Lot Restaurant
    $3,250,000
    2,300 SF

    Downtown Charleston Corner Lot Restaurant

    High-profile corner lot with renovated restaurant in downtown Charleston.

    211 Rutledge Ave, Charleston, SC 29403
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    Turn-Key Restaurant in Historic District
    $3,650,000
    2,890 SF

    Turn-Key Restaurant in Historic District

    Restaurant opportunity in downtown Charleston's historic district.

    5 Cumberland St, Charleston, SC 29401
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    Multi-Tenant Flex Building
    $2,175,000
    2.00 Acres

    Multi-Tenant Flex Building

    Partially renovated flex suites with new HVAC and flexible leasing, backed by ample parking on a light industrial site.

    1007 Bankton Circle, Hanahan, SC 29410
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    Charleston Land Mixed-Use Opportunity
    $1,050,000
    0.13 Acres

    Charleston Land Mixed-Use Opportunity

    Vacant parcel on King St, ideal for mixed-use development.

    975 King Street, Charleston, SC 29403
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    West Ashley Commercial Land Parcel
    $800,000
    4.02 Acres

    West Ashley Commercial Land Parcel

    4.02 AC wooded commercial land for sale near I-526.

    2469 Ashley River Rd, Charleston, SC 29414
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    General Commercial Land with Visibility
    $1,200,000
    2.03 Acres

    General Commercial Land with Visibility

    Three contiguous parcels offer high visibility and flexible commercial use potential near major regional access points.

    209, 211, 213 S Goose Creek, Goose Creek, SC 29445
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    Moncks Corner Land For Sale
    $395,000
    5.00 Acres

    Moncks Corner Land For Sale

    5 acres on Hwy 52, Moncks Corner. Priced to sell.

    220 N Highway 52, Moncks Corner, SC 29461
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    Berkeley County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 176 commercial real estate for sale in Berkeley County, SC, showcased through 176 active listings on our real estate platform. These investment opportunities span a total of 591,084 square feet of properties for sale, with an estimated market value of $228,159,484.

    Sale prices for business properties in Berkeley County, SC start at $209,999, averaging $3,802,658, and reaching up to $24,025,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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