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    Berkeley County, SC Commercial Real Estate for Sale

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    Greenville, SC Aiken, SC Beaufort, SC
    178 results
    Historic Charleston Mixed-Use Building
    $2,650,000
    4,923 SF

    Historic Charleston Mixed-Use Building

    59 Broad Street, Charleston, SC 29401

    Three-story mixed-use building in Charleston's historic commercial corridor.

    • Prime location on Broad Street in Charleston's historic commercial corridor
    • Approved entitlements for food & beverage use
    • Permit‑ready storefront renovation with accordion doors and updated facade
    • Approved addition of an 820 sq ft fourth‑floor penthouse
    • Mixed‑use building offering flexibility for owner‑occupancy or investment
    Updated: Mar 31
    View details
    Twin Garden Home with Pool
    $409,000
    2,375 SF

    Twin Garden Home with Pool

    108 Dresden Drive, Goose Creek, SC 29445

    Well-maintained home with pool, flex space, and community amenities.

    • Private in‑ground pool with new liner and screened‑in porch
    • One‑level living with vaulted ceilings and open‑concept design
    • Kitchen features granite countertops, spacious island, double ovens, new Bosch dishwasher, new rangetop, and pull‑out shelving
    • Climate‑controlled flex space, convertible to garage, suitable for office, gym, or guest suite
    • Low‑maintenance living with HOA‑covered lawn and shrub care
    Updated: Mar 4
    View details
    Renovated Duplex in Downtown Charleston
    $925,000
    1,461 SF

    Renovated Duplex in Downtown Charleston

    Turnkey duplex near MUSC & CofC, completed renovation in 2025.

    68 Lee Street unit: A & B, Charleston, SC 29403
    View details
    Bonneau Commercial Parcel For Sale
    $275,000
    1.00 Acre

    Bonneau Commercial Parcel For Sale

    One-acre commercial parcel in growing Bonneau, SC.

    1042 Bethera Road, Bonneau, SC 29431
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    Cleared Lot on Highway 17-A
    $200,000
    0.47 Acres

    Cleared Lot on Highway 17-A

    Cleared 0.47 acre lot with road frontage in Moncks Corner.

    231 S Live Oak Drive, Moncks Corner, SC 29461
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    Prime West Ashley Acreage Opportunity
    $999,000
    2.37 Acres

    Prime West Ashley Acreage Opportunity

    2.37 acres in West Ashley, ideal for development.

    736 Savage Road, Charleston, SC 29414
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    Moncks Corner Commercial Land Available
    $484,000
    2.76 Acres

    Moncks Corner Commercial Land Available

    2.76 acres of commercial land for sale in Moncks Corner.

    2086 S Live Oak Drive, Moncks Corner, SC 29461
    View details
    Commercial Lot on Red Bank
    $300,000
    0.20 Acres

    Commercial Lot on Red Bank

    High-traffic commercial lot available on Red Bank Road.

    201 Red Bank Rd, Goose Creek, SC 29445
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    2.37 Acres in Wando, SC
    $1,550,000
    2.37 Acres

    2.37 Acres in Wando, SC

    2.37 acres of commercial land with easy highway access.

    Clements Ferry Road, Wando, SC 29492
    View details
    Historic Charleston Four-Unit Building
    $5,500,000
    11,752 SF

    Historic Charleston Four-Unit Building

    Restored four-unit building in Charleston's Historic District.

    241 East Bay Street, Charleston, SC 29401
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    Daniel Island Deepwater Residential Enclave
    $8,250,000
    1.66 Acres

    Daniel Island Deepwater Residential Enclave

    Rare waterfront acreage suitable for residential or commercial development.

    1995 Daniel Island Drive, Charleston, SC 29492
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    Charleston Medical Property Investment
    $1,895,000

    Charleston Medical Property Investment

    Thriving medical property in Charleston, SC with favorable lease terms.

    2039 Savannah Highway, Charleston, SC 29407
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    Charleston Land Mixed-Use Opportunity
    $1,050,000
    0.13 Acres

    Charleston Land Mixed-Use Opportunity

    Vacant parcel on King St, ideal for mixed-use development.

    975 King Street, Charleston, SC 29403
    View details
    Marsh-Front Lot in Charleston, SC
    $149,000
    0.09 Acres

    Marsh-Front Lot in Charleston, SC

    Cleared marsh-front lot near Upper King Street and waterfront development.

    2311 Peonie Avenue, Charleston, SC 29405
    View details
    Moncks Corner Wooded Acreage Available
    $1,500,000
    18.00 Acres

    Moncks Corner Wooded Acreage Available

    18 acres of wooded land with development potential.

    Mount Pleasant Drive, Moncks Corner, SC 29461
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    Historic Charleston Mixed-Use Income Property
    $4,399,000
    4,252 SF

    Historic Charleston Mixed-Use Income Property

    Renovated mixed-use property in downtown Charleston with commercial and residential income.

    21 Broad Street, Charleston, SC 29401
    View details
    Moncks Corner Land For Sale
    $140,000
    1.09 Acres

    Moncks Corner Land For Sale

    1.09 acre lot in thriving Berkeley County, zoned Flex-1.

    Hwy 52, Moncks Corner, SC 29461
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    Hanahan Commercial Land For Sale
    $100,000

    Hanahan Commercial Land For Sale

    Commercial property in Hanahan, SC, zoned ''Town Center''.

    10 Carolyn Street, Hanahan, SC 29410
    View details
    Wando Commercial Land Opportunity
    $70,000
    0.86 Acres

    Wando Commercial Land Opportunity

    Prime commercial land for sale in Wando, South Carolina.

    481 Jessen Lane, Wando, SC 29492
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    New Commercial Facility on 5 Acres
    $1,750,000
    8,825 SF

    New Commercial Facility on 5 Acres

    New 8,825 SF facility on 5 acres in Moncks Corner.

    2350 Cooper Store Rd, Moncks Corner, SC 29461
    View details
    Vacant Lot in Moncks Corner
    $85,000
    1.00 Acre

    Vacant Lot in Moncks Corner

    One-acre vacant lot near Lake Moultrie, Summerville, and Moncks Corner.

    Yaremich Drive, Moncks Corner, SC 29461
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    Goose Creek Strip Center
    $930,000
    5,250 SF

    Goose Creek Strip Center

    Fully leased strip center in booming Goose Creek retail area.

    102 Berkeley Square Ln, Goose Creek, SC 29445
    View details
    Turn-Key Restaurant in Historic District
    $3,650,000
    2,890 SF

    Turn-Key Restaurant in Historic District

    Restaurant opportunity in downtown Charleston's historic district.

    5 Cumberland St, Charleston, SC 29401
    View details
    Moncks Corner Flex Land
    $150,000
    2.05 Acres

    Moncks Corner Flex Land

    2.05 acres of land with flexible zoning.

    089 Yaremich Road, Moncks Corner, SC 29461
    View details

    Berkeley County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 178 commercial real estate for sale in Berkeley County, SC, showcased through 178 active listings on our real estate platform. These investment opportunities span a total of 44,323,608 square feet of properties for sale, with an estimated market value of $57,375,910.

    Sale prices for business properties in Berkeley County, SC start at $70,000, averaging $1,334,323, and reaching up to $8,250,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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