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    Darlington County, SC Commercial Real Estate for Sale

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    58 properties
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    Two-Story Office Building
    Updated: Jul 1
    Two-Story Office Building

    311 W Home Ave, Hartsville, SC 29550

    $799,000
    7,759 sqft 0.82 AC lot
    7,759‑square‑foot two‑story office building constructed in 1977
    0.82‑acre property at 311 W Home Ave, Hartsville, SC 29550
    First floor includes fourteen additional private rooms or offices and a conference room
    Second floor features two large executive offices, three additional offices, and an open loft area
    Wraparound parking lot with abundant on‑site parking
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    Historic Bed & Breakfast with Guest House
    Updated: Aug 18
    Historic Bed & Breakfast with Guest House

    314 E Home Ave, Hartsville, SC 29550

    $735,000
    4,015 sqft 2.10 AC lot
    Main inn measures 4,015 square feet and was built in 1892
    Five‑bedroom, 5.5‑bath main inn
    Separate 1BR/1BA guest house with kitchen and living area
    2.1‑acre property at 314 E Home Ave, Hartsville, SC 29550
    Operating bed‑and‑breakfast with existing bookings
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    Open-Plan Retail Space
    Open-Plan Retail Space

    331 W Carolina Ave, Hartsville, SC 29550

    $1,200,000
    17,957 sqft 1.77 AC lot

    Commercial property with high ceilings, substantial parking, and recent roof improvements near downtown Hartsville.

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    See what stands out in Darlington County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

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    Commercial Land with Highway Frontage
    Commercial Land with Highway Frontage

    603 S Governor Williams Hwy, Darlington, SC 29532

    $725,000
    7 sqft

    Commercial land along S Governor Williams Hwy offers substantial road exposure for future development consideration.

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    Flex Space with Warehouse
    Flex Space with Warehouse

    756 S 4th Street, Hartsville, SC 29550

    $399,900
    4,800 sqft 1.12 AC lot

    Steel-and-metal commercial property combining front-office functions with warehouse and additional rear building space.

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    Office Building with Lobby
    Office Building with Lobby

    464 W Carolina Ave, Hartsville, SC 29550

    $198,000
    1,820 sqft 0.84 AC lot

    Multi-office layout includes a break area and two restrooms.

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    Restaurant Building Near Darlington Raceway
    Restaurant Building Near Darlington Raceway

    1207 Harry Byrd Hwy, Darlington, SC 29532

    $485,000
    2,188 sqft

    Brick restaurant property with camper hookup infrastructure near a major motorsports venue.

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    Darlington Convenience Store on 1.8 Acres
    Darlington Convenience Store on 1.8 Acres

    3316 Governor Williams Hwy North, Darlington, SC 29532

    $300,000
    2,850 sqft 1.80 AC lot

    2850 SF convenience store on 1.8 acres for sale.

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    Corner-Lot Grocery Building
    Corner-Lot Grocery Building

    130 S Sixth St, Hartsville, SC 29550

    $265,000
    1,100 sqft

    Existing seafood market with a new roof, heat pump, and central air.

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    Convenience Store Commercial Space
    Convenience Store Commercial Space

    305 N Main St, Darlington, SC 29532

    $265,000
    2,601 sqft

    Suitable for retail, takeout, and quick-service food operations in Darlington.

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    Two-Story Office Building
    Two-Story Office Building

    311 W Home Ave, Hartsville, SC 29550

    Contact for pricing
    7,759 sqft

    Flexible professional workspace includes private rooms, executive offices, meeting areas, and extensive on-site parking.

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    Three-Area Office Building
    Three-Area Office Building

    331 S 4th Street, Hartsville, SC 29550

    $299,900
    2,275 sqft 0.32 AC lot

    Stucco office property with two established tenants and a separate area available for occupancy.

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    Agricultural Land Parcel
    Agricultural Land Parcel

    Harry Byrd Hwy, Darlington, SC 29532

    $899,900
    35.37 AC lot

    Ag-zoned acreage in Darlington for residential or commercial lot development, with option to subdivide.

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    Open-Plan Retail Building
    Open-Plan Retail Building

    331 West Carolina Avenue, Hartsville, SC 29550

    Contact for pricing
    17,957 sqft 1.77 AC lot

    Commercial zoning, a flexible interior layout, and roof improvements completed within the past two years.

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    Agricultural Land with Woodlands
    Agricultural Land with Woodlands

    Pineville Road, Darlington, SC 29532

    $620,000
    28.10 AC lot

    Farm acreage combines tillable fields, mixed woodlands, and access from two roads.

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    Creekfront Commercial Land
    Creekfront Commercial Land

    N Main St, Darlington, SC 29532

    $215,000
    12.72 AC lot

    Mostly cleared commercial tract with creek frontage and Commercial zoning.

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    Restaurant Building with Camper Hookups
    Restaurant Building with Camper Hookups

    1207 HARRY BYRD HWY, Darlington, SC 29532

    Contact for pricing
    2,188 sqft

    Existing restaurant improvements include four electric camper hookups behind the property.

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    Tillable Farmland With Road Frontage
    Tillable Farmland With Road Frontage

    Auction Ave, Darlington, SC 29532

    $235,000
    10.00 AC lot

    Open agricultural acreage at a two-road corner with frontage along Pineville Road and Auction Avenue.

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    Office and Retail Investment Opportunity
    Office and Retail Investment Opportunity

    139 CASHUA ST, Darlington, SC 29532

    Contact for pricing
    3,085 sqft 0.28 AC lot

    Commercial property with office, retail, and residential income potential.

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    Waterfront Hunting Land
    Waterfront Hunting Land

    W Bobo Newsom Hwy, Hartsville, SC 29550

    $1,700,000
    531.91 AC lot

    Large South Carolina recreational tract with diverse habitat, multiple water features, agricultural fields, and conservation-protected homesite flexibility.

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    Historic Restaurant with Bar
    Historic Restaurant with Bar

    26 PUBLIC SQ DARLINGTON SC 29532, Darlington, SC 29532

    Contact for pricing
    1,720 sqft 0.05 AC lot

    Downtown Darlington setting with kitchen, dining, bar, office, restrooms, and included restaurant equipment.

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    Pine-Planted Agricultural Land
    Pine-Planted Agricultural Land

    Ruby Rd (87.15 acres), Hartsville, SC 29550

    $435,000
    87.15 AC lot

    AG-zoned rural acreage planted throughout with long-leaf pines and accessed from Ruby Road.

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    Renovated Warehouse with Multiple Doors
    Renovated Warehouse with Multiple Doors

    223 West Pearl Street, Lamar, SC 29069

    Contact for pricing
    50,000 sqft

    Renovated +/-50,000 SF warehouse features drive-in and dock-high doors, new lighting, updated restrooms, and upgraded parking.

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    Agricultural Land with Road Frontage
    Agricultural Land with Road Frontage

    Gallowaytown Road, Hartsville, SC 29550

    $189,000
    27.00 AC lot

    Open agricultural land with direct road access and an ag zoning designation.

    View details

    Darlington County, SC Commercial Real Estate Market Trends and Statistics

    Explore 72 commercial real estate for sale in Darlington County, SC, showcased through 58 active listings on our real estate platform. These investment opportunities span a total of 260,476 square feet of properties for sale, with an estimated market value of $12,205,250.

    Sale prices for business properties in Darlington County, SC start at $41,000, averaging $369,856, and reaching up to $1,700,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Darlington County Real Estate Agencies

    Realmo connects you with licensed Darlington County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Brown & Coker Realty
    157 West Carolina Ave Hartsville, SC 29550
    Phone: 18433836765
    www.browncokerrealty.com

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