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South Carolina

Darlington County, SC Commercial Real Estate for Sale

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Columbia, SC Hilton Head Island, SC Greenville, SC Myrtle Beach, SC Spartanburg, SC Aiken, SC Anderson, SC Charleston, SC

52 properties

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Two-Story Office Building

Updated: Jul 1

Two-Story Office Building

311 W Home Ave, Hartsville, SC 29550

$799,000

7,759 sqft 0.82 AC lot

7,759‑square‑foot two‑story office building constructed in 1977
0.82‑acre property at 311 W Home Ave, Hartsville, SC 29550
First floor includes fourteen additional private rooms or offices and a conference room
Second floor features two large executive offices, three additional offices, and an open loft area
Wraparound parking lot with abundant on‑site parking

Historic Bed & Breakfast with Guest House

Updated: Aug 18

Historic Bed & Breakfast with Guest House

314 E Home Ave, Hartsville, SC 29550

$735,000

4,015 sqft 2.10 AC lot

Main inn measures 4,015 square feet and was built in 1892
Five‑bedroom, 5.5‑bath main inn
Separate 1BR/1BA guest house with kitchen and living area
2.1‑acre property at 314 E Home Ave, Hartsville, SC 29550
Operating bed‑and‑breakfast with existing bookings

Grocery-Anchored Commercial Property

Grocery-Anchored Commercial Property

401 Pearl St, Darlington, SC 29532

$1,309,100

23,108 sqft 2.78 AC lot

The site combines a grocery-anchored building with two attached commercial spaces.

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Commercial Land with Highway Frontage

Commercial Land with Highway Frontage

603 S Governor Williams Hwy, Darlington, SC 29532

$725,000

7 sqft

Commercial land along S Governor Williams Hwy offers substantial road exposure for future development consideration.

Open-Plan Retail Space

Open-Plan Retail Space

331 W Carolina Ave, Hartsville, SC 29550

$1,200,000

17,957 sqft 1.77 AC lot

Commercial property with high ceilings, substantial parking, and recent roof improvements near downtown Hartsville.

Flex Space with Warehouse

Flex Space with Warehouse

756 S 4th Street, Hartsville, SC 29550

$399,900

4,800 sqft 1.12 AC lot

Steel-and-metal commercial property combining front-office functions with warehouse and additional rear building space.

Restaurant Building Near Darlington Raceway

Restaurant Building Near Darlington Raceway

1207 Harry Byrd Hwy, Darlington, SC 29532

$400,000

2,188 sqft

Brick restaurant property with camper hookup infrastructure near a major motorsports venue.

Two-Story Office Building

Two-Story Office Building

311 W Home Ave, Hartsville, SC 29550

Contact for pricing

7,759 sqft

Flexible professional workspace includes private rooms, executive offices, meeting areas, and extensive on-site parking.

Three-Area Office Building

Three-Area Office Building

331 S 4th Street, Hartsville, SC 29550

$299,900

2,275 sqft 0.32 AC lot

Stucco office property with two established tenants and a separate area available for occupancy.

Corner-Lot Grocery Building

Corner-Lot Grocery Building

130 S Sixth St, Hartsville, SC 29550

$265,000

1,100 sqft

Existing seafood market with a new roof, heat pump, and central air.

Open-Plan Retail Building

Open-Plan Retail Building

331 West Carolina Avenue, Hartsville, SC 29550

Contact for pricing

17,957 sqft 1.77 AC lot

Commercial zoning, a flexible interior layout, and roof improvements completed within the past two years.

Convenience Store Commercial Space

Convenience Store Commercial Space

305 N Main St, Darlington, SC 29532

$265,000

2,601 sqft

Suitable for retail, takeout, and quick-service food operations in Darlington.

Office Building with Lobby

Office Building with Lobby

464 W Carolina Ave, Hartsville, SC 29550

$187,500

1,820 sqft 0.84 AC lot

Multi-office layout includes a break area and two restrooms.

Restaurant Building with Camper Hookups

Restaurant Building with Camper Hookups

1207 HARRY BYRD HWY, Darlington, SC 29532

Contact for pricing

2,188 sqft

Existing restaurant improvements include four electric camper hookups behind the property.

Agricultural Land Parcel

Agricultural Land Parcel

Harry Byrd Hwy, Darlington, SC 29532

$899,900

35.37 AC lot

Ag-zoned acreage in Darlington for residential or commercial lot development, with option to subdivide.

Creekfront Commercial Land

Creekfront Commercial Land

N Main St, Darlington, SC 29532

$215,000

12.72 AC lot

Mostly cleared commercial tract with creek frontage and Commercial zoning.

Office and Retail Investment Opportunity

Office and Retail Investment Opportunity

139 CASHUA ST, Darlington, SC 29532

Contact for pricing

3,085 sqft 0.28 AC lot

Commercial property with office, retail, and residential income potential.

Agricultural Land with Woodlands

Agricultural Land with Woodlands

Pineville Road, Darlington, SC 29532

$620,000

28.10 AC lot

Farm acreage combines tillable fields, mixed woodlands, and access from two roads.

Retail Building with Multiple Entrances

Retail Building with Multiple Entrances

310 Hartsville Crossing Blvd, Hartsville, SC 29550

$2,200,000

18,000 sqft

Several storefront access points allow the building to serve one operation or be arranged for multiple occupants.

Tillable Farmland With Road Frontage

Tillable Farmland With Road Frontage

Auction Ave, Darlington, SC 29532

$235,000

10.00 AC lot

Open agricultural acreage at a two-road corner with frontage along Pineville Road and Auction Avenue.

Historic Restaurant with Bar

Historic Restaurant with Bar

26 PUBLIC SQ DARLINGTON SC 29532, Darlington, SC 29532

Contact for pricing

1,720 sqft 0.05 AC lot

Downtown Darlington setting with kitchen, dining, bar, office, restrooms, and included restaurant equipment.

Agricultural Land with Pond

Agricultural Land with Pond

Hudson Street, Lamar, SC 29069

$269,000

42.00 AC lot

Open fields and pasture support ongoing agricultural use, with an irrigation pond on the property.

Renovated Warehouse with Multiple Doors

Renovated Warehouse with Multiple Doors

223 West Pearl Street, Lamar, SC 29069

Contact for pricing

50,000 sqft

Renovated +/-50,000 SF warehouse features drive-in and dock-high doors, new lighting, updated restrooms, and upgraded parking.

Retail Space with Multiple Entrances

Retail Space with Multiple Entrances

310 Hartsville Crossing Boulevard, Hartsville, SC 29550

$2,200,000

1.50 AC lot

A single-level layout is complemented by surface parking and central air conditioning.

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Darlington County, SC Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Darlington County, SC, showcased through 52 active listings on our real estate platform. These investment opportunities span a total of 277,309 square feet of properties for sale, with an estimated market value of $18,078,975.

Sale prices for business properties in Darlington County, SC start at $41,000, averaging $488,620, and reaching up to $2,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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