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    Darlington County, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    47 results
    Former Grocery Store with Ample Parking
    $1,200,000
    17,957 SF
    Former Grocery Store with Ample Parking

    331 W Carolina Ave, Hartsville, SC 29550

    A former grocery store with an open layout, 12-foot ceilings, and about 81 parking spaces in Hartsville.
    • Former grocery store with approximately 17,957 SF of commercial space on 1.77 acres at 331 W. Carolina Avenue
    • 12‑foot ceilings and an open floor plan suited for retail, warehouse, distribution, office, fitness, or redevelopment use
    • Site includes approximately 81 parking spaces for customers, employees, and tenants
    • Roof improvements completed within the past two years
    • Conveniently located minutes from Downtown Hartsville
    Updated: May 13
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    Warehouse with Front Office Space
    $399,900
    4,800 SF
    Warehouse with Front Office Space

    756 S 4th Street, Hartsville, SC 29550

    Warehouse and a separate metal building at the rear, with office space at the front and ample parking.
    • Warehouse plus an extra metal building in back, approximately 2,400 SF total
    • Office space in the front includes a reception desk, 2 offices, and 2 half baths
    • Built in 1974 with steel and metal skin construction
    • Concrete flooring throughout
    • Window unit(s) cooling
    Updated: May 15
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    Office Building with Lobby and Break Area
    $205,000
    1,820 SF
    Office Building with Lobby and Break Area

    Standalone office building with multiple offices, a break area, and two restrooms in a high-traffic corridor.

    464 W Carolina Ave, Hartsville, SC 29550

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    Auto Service Warehouse with Roll-Up Doors
    $130,000
    1,641 SF
    Auto Service Warehouse with Roll-Up Doors

    Two roll-up doors, additional storage, and fencing support flexible light auto or small business use.

    200 Race Track Road, Hartsville, SC 29550

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    Freestanding Retail Asset For Sale
    $2,200,000
    18,000 SF
    Freestanding Retail Asset For Sale

    Highly visible retail building in a growing commercial corridor.

    310 Hartsville Crossing Boulevard, Hartsville, SC 29550

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    Animal Boarding and Training Facility
    $270,000
    8,800 SF
    Animal Boarding and Training Facility

    Purpose-built boarding setup with heated office, extensive kennels, and dedicated water and septic systems on 3.7 acres.

    2104 Hearthstone Road, Hartsville, SC 29550

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    Commercial Land Parcel
    $600,000
    5.91 Acres
    Commercial Land Parcel

    Commercially zoned land near a medical center and schools, positioned along a heavily traveled bypass corridor.

    W BoBo Newsom Hwy, Hartsville, SC 29550

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    Agricultural Land Parcel
    $899,900
    35.37 Acres
    Agricultural Land Parcel

    Ag-zoned acreage in Darlington for residential or commercial lot development, with option to subdivide.

    Harry Byrd Hwy, Darlington, SC 29532

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    Office and Retail Investment Opportunity
    $424,000
    3,085 SF
    Office and Retail Investment Opportunity

    Commercial property with office, retail, and residential income potential.

    139 CASHUA ST, Darlington, SC 29532

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    Darlington Convenience Store on 1.8 Acres
    $300,000
    2,850 SF
    Darlington Convenience Store on 1.8 Acres

    2850 SF convenience store on 1.8 acres for sale.

    3316 Governor Williams Hwy North, Darlington, SC 29532

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    Commercial Land for Mixed-Use Development
    $199,999
    11.47 Acres
    Commercial Land for Mixed-Use Development

    11.47-acre commercial-zoned parcel outside city limits with city water and sewer available for flexible development planning.

    1403 S Fifth Street, Hartsville, SC 29550

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    Hartsville Retail Investment Opportunity
    $425,000
    4,500 SF
    Hartsville Retail Investment Opportunity

    4,500 sq ft building, $30,000 annual rent.

    524 Poole St, Hartsville, SC 29550

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    Corner Lot Retail Building
    $265,000
    1,100 SF
    Corner Lot Retail Building

    Corner retail building with a new roof and HVAC, currently operating as a seafood market and adaptable for other retail uses.

    130 S Sixth St, Hartsville, SC 29550

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    Diverse Land with Millpond Near Hartsville
    $1,825,000
    531.91 Acres
    Diverse Land with Millpond Near Hartsville

    530-acre property with water features, conservation easement, near Hartsville.

    0 W Bobo Newsom Hwy, Hartsville, SC 29550

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    Agricultural Land Development Tract
    $230,000
    14.47 Acres
    Agricultural Land Development Tract

    14.47 acres of agricultural land on N Fifth Street in Hartsville, SC, offering potential for residential or commercial rezoning.

    14.47 acres N 5th Street, Hartsville, SC 29550

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    Open Land with Road Frontage
    $189,000
    27.00 Acres
    Open Land with Road Frontage

    Agricultural-zoned open land offering about 300 feet of road frontage for flexible rural use.

    Gallowaytown Road, Hartsville, SC 29550

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    Commercial Building with Mobile Hook-Up
    $99,500
    1,568 SF
    Commercial Building with Mobile Hook-Up

    Commercial building with business potential and mobile home hook-up.

    2129 N Governor Williams Hwy, Darlington, SC 29540

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    Planted Pine Farmland Tract
    $435,000
    87.15 Acres
    Planted Pine Farmland Tract

    Dry AG-zoned acreage planted corner to corner in long-leaf pines, offering an established forestry base for future use.

    Ruby Rd (87.15 acres), Hartsville, SC 29550

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    Agricultural Land with Pond
    $168,000
    24.00 Acres
    Agricultural Land with Pond

    24-acre AG-zoned tract with clear areas, wooded sections, and a small pond for flexible agricultural use.

    Hwy 15, Hartsville, SC 29550

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    Unzoned Land Near Highway 52
    $120,000
    5.60 Acres
    Unzoned Land Near Highway 52

    5.6 acre property near Hwy 52, Darlington, SC.

    1840 S Main St, Darlington, SC 29532

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    Hartsville Office Building For Sale
    $1,100,000
    5,000 SF
    Hartsville Office Building For Sale

    5,000 sq ft office building in the heart of Hartsville.

    146 Cargill Way, Hartsville, SC 29550

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    Commercial Land with Multi-Road Access
    $41,000
    2.95 Acres
    Commercial Land with Multi-Road Access

    Commercial-zoned land in North Hartsville with access to three roads and planned signage on the N Fifth Street side.

    2.95 acres Warehouse Road, Hartsville, SC 29550

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    Fully Leased Commercial Property
    $250,000
    2,400 SF
    Fully Leased Commercial Property

    Commercial property for sale, currently fully leased.

    518 Poole St, Hartsville, SC 29550

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    Timber and Orchard Tract
    $222,900
    27.54 Acres
    Timber and Orchard Tract

    27+ acre property with natural pine, open fields, and a pecan orchard for private residences or recreation.

    E Home Ave/ E Carolina Avenue, Hartsville, SC 29550

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    Darlington County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Darlington County, SC, showcased through 47 active listings on our real estate platform. These investment opportunities span a total of 113,449 square feet of properties for sale, with an estimated market value of $12,432,640.

    Sale prices for business properties in Darlington County, SC start at $85,000, averaging $592,030, and reaching up to $2,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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