Mesa County, CO Commercial Real Estate for Sale

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510 properties
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Remodeled Flex Space with Loading Dock
Updated: Jun 9
Remodeled Flex Space with Loading Dock

15757 57 1/2 Road, Collbran, CO 81624

$520,000
4,960 sqft 0.29 AC lot
4,960‑square‑foot flex property on 0.29 acres
Two insulated bays with concrete floors and electrically operated overhead doors
220 electrical service, exterior loading dock, and 5‑ton overhead sliding hoist
Three carpeted offices with furniture plus a break room
Forced‑air heat, air conditioning, mini‑split system, and overhead shop heating
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Remodeled Flex Space With Office Wing
Updated: Apr 22
Remodeled Flex Space With Office Wing

15757 57 1/2 Road, Collbran, CO 81624

$520,000
4,960 sqft 0.29 AC lot
4,960 SF flex property on 0.29 acres
Two insulated shop bays with concrete floors and powered overhead doors
220 electrical service, exterior loading dock, and 5‑ton overhead sliding hoist
Three furnished offices plus break room and tiled half bath
Commercial zoning with private well, storage shed, and paved parking
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Six-Office Building with Conference Room
Six-Office Building with Conference Room

15739 Pearl Avenue, Collbran, CO 81624

$420,000
1,440 sqft 0.39 AC lot

Furnished office configuration includes reception, conference, and break-room areas.

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Freestanding Office Building with Parking
Freestanding Office Building with Parking

516 28 Rd, Grand Junction, CO 81501

$2,600,000
12,360 sqft 1.45 AC lot

Freestanding 12,360 SF office building on a 1.45-acre lot with direct access from 28 Road.

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Brick Restaurant and Saloon
Brick Restaurant and Saloon

108 Main Street, Collbran, CO 81624

$399,000
2,214 sqft 0.14 AC lot

Established food-and-beverage operation with dining space, bar amenities, furnishings, equipment, and inventory included.

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Nursery and Garden Center with Greenhouses
Nursery and Garden Center with Greenhouses

1702 10 Road, Mack, CO 81525

$3,995,000
9,346 sqft 78.59 AC lot

Established wholesale and retail nursery operation with greenhouses, a manager’s home, plant inventory, and senior irrigation water rights.

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Nursery and Garden Center with Greenhouses
Nursery and Garden Center with Greenhouses

1701 10 Road, Mack, CO 81525

$3,995,000
9,346 sqft 78.59 AC lot

Nursery operation includes greenhouses, plant inventory, and a manager’s home.

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Mixed-Use Property with Shop Space
Mixed-Use Property with Shop Space

2180 I-70 Frontage Rd, De Beque, CO 81630

$2,800,000
14,000 sqft

Office, two-bay shop, and rear industrial workspace include overhead crane equipment.

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Operational Sod Farm with Shop
Operational Sod Farm with Shop

1161 23 Road, Grand Junction, CO 81505

$1,999,000
3,200 sqft 38.26 AC lot

Working agricultural property with sod production, owned water rights, irrigation infrastructure, equipment, and a remodeled residence.

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Three-Sided Commercial Land
Three-Sided Commercial Land

404 W Aspen Avenue, Fruita, CO 81521

$859,900
0.94 AC lot

DMU-zoned development site with utilities available and access from multiple streets.

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Second-Floor Office Suite
Second-Floor Office Suite

1048 Independent Avenue #B205, Grand Junction, CO 81505

$557,512
2,456 sqft

The walk-up suite combines private offices, a conference room, a break area, and shared restrooms in a practical workplace layout.

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Fenced Agricultural Land
Fenced Agricultural Land

724 Elberta Avenue, Palisade, CO 81526

$550,000
0.95 AC lot

Fenced parcel in the Hospitality Agriculture zoning district with water, sewer, and natural gas on site.

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Commercial Land in HA District
Commercial Land in HA District

724 Elberta Avenue, Palisade, CO 81526

$550,000
0.95 AC lot

Fenced commercial parcel with on-site water, sewer, natural gas, and irrigation service near Palisade’s agricultural corridor.

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Industrial Flex Property with Shop Space
Industrial Flex Property with Shop Space

378 28 Road, Grand Junction, CO 81501

$750,000
2,720 sqft 1.14 AC lot

Three contiguous parcels combine workshop, office, storage, and municipal utility infrastructure for flexible commercial operations.

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Commercial Land with Approved Storage Plans
Commercial Land with Approved Storage Plans

2298 Tall Grass, Grand Junction, CO 81505

$900,000
2.45 AC lot

Vacant commercial land with approved self-storage plans, street-accessible utilities, and completed development documentation.

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Riverfront Commercial Land
Riverfront Commercial Land

535 Hale Avenue, Grand Junction, CO 81501

$3,200,000
3.20 AC lot

A level parcel within a mixed-use outdoor recreation development, with utilities and irrigation water in place.

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Quick-Service Restaurant Building
Quick-Service Restaurant Building

2878 North Ave, Grand Junction, CO 81501

$1,685,000
3,173 sqft

Built in 2013 with a fully equipped commercial kitchen on a high-profile corner lot near major retail.

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Industrial Land in Business Park
Industrial Land in Business Park

1583 River Road, Fruita, CO 81521

$588,060
3.00 AC lot

Industrial-zoned parcel with utilities in the road, curbs, and gutters.

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Well-Maintained Commercial Property For Sale
Well-Maintained Commercial Property For Sale

688 45 Rd, De Beque, CO 81630

$1,500,000
9,780 sqft 5.71 AC lot

Commercial property with global tenant, automatic security, and vehicle service.

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Three-Lot Commercial Land
Three-Lot Commercial Land

645, 643, 641 Market Street, Grand Junction, CO 81505

$3,475,000
3.90 AC lot

Three contiguous parcels offer a flexible commercial development footprint with public water service.

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Mixed-Use Development Land with Shop
Mixed-Use Development Land with Shop

2379 G Rd, Grand Junction, CO 81505

$2,500,000
4,400 sqft 4.58 AC lot

4.58-acre fenced site with a ground-floor shop and small office, plus a mezzanine apartment shell.

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Corner Commercial Land Parcel
Corner Commercial Land Parcel

288 27 Road, Grand Junction, CO 81503

$459,000
2.81 AC lot

Vacant MU-2 land at 27 Road and Unaweep, near schools, parks, shopping centers, grocery retailers, bike paths, and bus routes.

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Flex Space with Overhead Door
Flex Space with Overhead Door

1048 Independent Avenue #A105, Grand Junction, CO 81505

$377,728
1,664 sqft

Office and warehouse areas support contractor, e-commerce, and distribution operations.

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Commercial Land Near Gas Station
Commercial Land Near Gas Station

32190 Willow Bend Road, Whitewater, CO 81527

$157,500
1.54 AC lot

MU-C zoning places this Highway 50 parcel beside the Golden Gate Gas Station.

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Mesa County, CO Commercial Real Estate Market Trends and Statistics

Explore 510 commercial real estate for sale in Mesa County, CO, showcased through 510 active listings on our real estate platform. These investment opportunities span a total of 2,231,177 square feet of properties for sale, with an estimated market value of $524,182,204.

Sale prices for business properties in Mesa County, CO start at $60,000, averaging $1,185,932, and reaching up to $12,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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