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    Mesa County, CO Commercial Real Estate for Sale

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    Denver, CO Colorado Springs, CO Pueblo, CO
    271 results
    Move-in Ready Office Building
    $450,000
    1,440 SF

    Move-in Ready Office Building

    15739 Pearl Avenue, Collbran, CO 81624

    Upscale office building in mountain valley community.

    • Move‑in‑ready office space with state‑of‑the‑art furniture and accessories included.
    • Excellent visibility due to highway frontage location on busy Highway 330.
    • Features six private offices and an impressive conference room.
    • Includes convenient reception area, break room, and secure drop box.
    • Climate control with gas heat and central air (LG Inverter system).
    Updated: Jan 29
    View details
    Profitable Liquor Store Opportunity
    $599,000
    1,842 SF

    Profitable Liquor Store Opportunity

    715 Horizon Drive, Grand Junction, CO 81506

    Established liquor store for sale in Grand Junction, Colorado.

    • Proven profitability with documented profit and loss history.
    • Attractive 6.5% cap rate, ideal for investors.
    • Prime location in a high‑traffic area with excellent visibility.
    • Turnkey business opportunity.
    • Efficient retail space designed for customer convenience.
    Updated: Mar 9
    View details
    Grand Junction Commercial Land Opportunity
    $950,000
    0.60 Acres

    Grand Junction Commercial Land Opportunity

    Prime commercial land with high visibility and strong growth potential.

    945 Dominguez Avenue, Grand Junction, CO 81503
    View details
    Grand Junction Commercial Outparcel For Sale
    $585,000
    0.69 Acres

    Grand Junction Commercial Outparcel For Sale

    0.69-acre commercial outparcel in high-traffic shopping center.

    2550 American Way, Grand Junction, CO 81501
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    Grand Junction Commercial Opportunity
    $850,000
    4.33 Acres

    Grand Junction Commercial Opportunity

    4.33 acres with warehouse, ready for immediate occupancy.

    760 21 1/2 Road, Grand Junction, CO 81505
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    Profitable Liquor Store Opportunity
    $599,000
    1,842 SF

    Profitable Liquor Store Opportunity

    Established liquor store for sale in Grand Junction, Colorado.

    715 Horizon Drive, Grand Junction, CO 81506
    View details
    Grand Junction Commercial Investment Opportunity
    $500,000

    Grand Junction Commercial Investment Opportunity

    NNN investment opportunity with long-term tenant in Grand Junction, CO.

    2472 Patterson Road unit: 10, Grand Junction, CO 81505
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    Established Restaurant and Saloon on Main
    $399,000
    2,214 SF

    Established Restaurant and Saloon on Main

    Turnkey restaurant and saloon in Collbran, Colorado with strong community support.

    108 Main Street, Collbran, CO 81624
    View details
    Iconic Grand Junction Business Opportunity
    $1,700,000

    Iconic Grand Junction Business Opportunity

    Local landmark business and property for sale in Grand Junction.

    581 29 Road, Grand Junction, CO 81504
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    Multi-Tenant Office Investment Opportunity
    $4,050,000

    Multi-Tenant Office Investment Opportunity

    Well-maintained office property with stable occupancy in Grand Junction, CO.

    700 Belford Avenue, Grand Junction, CO 81501
    View details
    Horizon Drive Commercial Development Land
    $779,900
    0.93 Acres

    Horizon Drive Commercial Development Land

    Commercial land with high visibility, suitable for various development projects.

    697 27 1/2 Court, Grand Junction, CO 81506
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    Horizon Drive Commercial Development Land
    $779,900
    0.93 Acres

    Horizon Drive Commercial Development Land

    Prime commercial land on Horizon Drive, Grand Junction, Colorado.

    697 27 1/2 Court, Grand Junction, CO 81506
    View details
    Prime Commercial Land Near I-70
    $850,000
    4.88 Acres

    Prime Commercial Land Near I-70

    4.88-acre commercial parcel with high visibility near I-70.

    853 Raptor Road, Fruita, CO 81521
    View details
    Multi-Tenant Commercial Building For Sale
    $875,000

    Multi-Tenant Commercial Building For Sale

    Multi-tenant commercial building in high-visibility location, suitable for various users.

    3198 F Road, Grand Junction, CO 81504
    View details
    Grand Junction Commercial Land Available
    $1,950,000
    1.85 Acres

    Grand Junction Commercial Land Available

    1.85 acres in downtown Grand Junction ready for development.

    2815 Grand Avenue, Grand Junction, CO 81505
    View details
    Move-in Ready Commercial Office Building
    $450,000
    1,440 SF

    Move-in Ready Commercial Office Building

    Upscale office building in Collbran, Colorado, perfect for growing business.

    15739 Pearl Street, Collbran, CO 81624
    View details
    Prime Development Site, Grand Junction
    $395,000
    1.61 Acres

    Prime Development Site, Grand Junction

    1.6-acre shovel-ready lot in a high-traffic retail corridor.

    2785 Acrin Avenue, Grand Junction, CO 81503
    View details
    Mountain Retreat with Cabin
    $400,000
    36.70 Acres

    Mountain Retreat with Cabin

    Secluded mountain property with cabins and recreational opportunities.

    22991 Divide Creek Rd, Collbran, CO 81624
    View details
    Turn-Key Restaurant/Retail Space Available
    $2,000,000
    7,269 SF

    Turn-Key Restaurant/Retail Space Available

    Restaurant/retail space with full kitchen, bar, and recent upgrades.

    3245 I-70 Business Loop, Clifton, CO 81520
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    Commercial Land in Grand Junction
    $175,000
    0.29 Acres

    Commercial Land in Grand Junction

    0.29 acre lot zoned I-1, suitable for business.

    354 Bonny Street, Grand Junction, CO 81501
    View details
    Palisade Corner Lot Ready to Build
    $298,000
    0.14 Acres

    Palisade Corner Lot Ready to Build

    Prime corner lot in downtown Palisade with mixed-use zoning.

    105 Main Street, Palisade, CO 81526
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    Grand Junction Commercial Opportunity
    $550,000
    1.64 Acres

    Grand Junction Commercial Opportunity

    Located in Foresight Park, suitable for various commercial uses.

    625 Hollingsworth Street, Grand Junction, CO 81505
    View details
    Grand Junction Historic District Multifamily
    $799,900
    2,736 SF

    Grand Junction Historic District Multifamily

    Versatile property in Grand Junction's 7th Street Historic District.

    815 N 7th Street, Grand Junction, CO 81501
    View details
    Whitewater, CO Commercial Land
    $897,000
    2.06 Acres

    Whitewater, CO Commercial Land

    Two-acre commercial parcels with highway visibility in growing Whitewater, CO.

    300 Highway 141, Whitewater, CO 81527
    View details

    Mesa County, CO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 271 commercial real estate for sale in Mesa County, CO, showcased through 271 active listings on our real estate platform. These investment opportunities span a total of 319,503,888 square feet of properties for sale, with an estimated market value of $158,490,788.

    Sale prices for business properties in Mesa County, CO start at $65,000, averaging $1,200,687, and reaching up to $7,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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