Mesa County, CO Commercial Real Estate for Sale

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573 properties
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Remodeled Flex Space with Loading Dock
Updated: Jun 9
Remodeled Flex Space with Loading Dock

15757 57 1/2 Road, Collbran, CO 81624

$520,000
4,960 sqft 0.29 AC lot
4,960‑square‑foot flex property on 0.29 acres
Two insulated bays with concrete floors and electrically operated overhead doors
220 electrical service, exterior loading dock, and 5‑ton overhead sliding hoist
Three carpeted offices with furniture plus a break room
Forced‑air heat, air conditioning, mini‑split system, and overhead shop heating
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Remodeled Flex Space With Office Wing
Updated: Apr 22
Remodeled Flex Space With Office Wing

15757 57 1/2 Road, Collbran, CO 81624

$520,000
4,960 sqft 0.29 AC lot
4,960 SF flex property on 0.29 acres
Two insulated shop bays with concrete floors and powered overhead doors
220 electrical service, exterior loading dock, and 5‑ton overhead sliding hoist
Three furnished offices plus break room and tiled half bath
Commercial zoning with private well, storage shed, and paved parking
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Six-Office Building with Conference Room
Six-Office Building with Conference Room

15739 Pearl Avenue, Collbran, CO 81624

$420,000
1,440 sqft 0.39 AC lot

Furnished office configuration includes reception, conference, and break-room areas.

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Commercial Kitchen Facility
Commercial Kitchen Facility

2853 North Ave, Grand Junction, CO 81501

$1,150,000
8,869 sqft 0.91 AC lot

Built in 2001, the facility combines a full commercial kitchen with dining, office, and flexible room areas.

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Brick Restaurant and Saloon
Brick Restaurant and Saloon

108 Main Street, Collbran, CO 81624

$399,000
2,214 sqft 0.14 AC lot

Established food-and-beverage operation with dining space, bar amenities, furnishings, equipment, and inventory included.

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Nursery and Garden Center with Greenhouses
Nursery and Garden Center with Greenhouses

1701 10 Road, Mack, CO 81525

$3,995,000
9,346 sqft 78.59 AC lot

Agricultural-zoned nursery operation with irrigation water rights, greenhouse improvements, a manager’s residence, and wholesale and retail capabilities.

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Nursery Property with Greenhouses
Nursery Property with Greenhouses

1702 10 Road, Mack, CO 81525

$3,995,000
9,346 sqft 78.59 AC lot

Established wholesale and retail nursery operation with greenhouses, plant inventory, and a manager’s residence.

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Flex Property with Crane-Equipped Shops
Flex Property with Crane-Equipped Shops

2180 I-70 Frontage, De Beque, CO 81630

$1,800,000
14,000 sqft

Office and shop areas are arranged across front and rear buildings.

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Operational Sod Farm with Shop
Operational Sod Farm with Shop

1161 23 Road, Grand Junction, CO 81505

$1,999,000
3,200 sqft 38.26 AC lot

Working agricultural property with sod production, owned water rights, irrigation infrastructure, equipment, and a remodeled residence.

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Equestrian Estate with Indoor Arena
Equestrian Estate with Indoor Arena

1577 14 1/2 Road, Loma, CO 81524

$2,449,000
3,871 sqft 30.00 AC lot

Purpose-built horse facility with barns, arenas, irrigated fields, and residential accommodations.

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Freestanding Office Building with Parking
Freestanding Office Building with Parking

516 28 Rd, Grand Junction, CO 81501

$3,200,000
12,360 sqft 1.45 AC lot

Freestanding 12,360 SF office building on a 1.45-acre lot with direct access from 28 Road.

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Hospitality Agriculture Commercial Land
Hospitality Agriculture Commercial Land

724 Elberta Avenue, Palisade, CO 81526

$550,000
0.95 AC lot

HA-zoned parcel with on-site water, irrigation, sewer, and natural gas infrastructure.

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Industrial Land in Business Park
Industrial Land in Business Park

1583 River Road, Fruita, CO 81521

$588,060
3.00 AC lot

Industrial-zoned parcel with utilities in the road, curbs, and gutters.

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Second-Floor Office Suite
Second-Floor Office Suite

1048 Independent Avenue #B205, Grand Junction, CO 81505

$557,512
2,456 sqft

The walk-up suite combines private offices, a conference room, a break area, and shared restrooms in a practical workplace layout.

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Three-Lot Commercial Land
Three-Lot Commercial Land

645, 643, 641 Market Street, Grand Junction, CO 81505

$3,475,000
3.90 AC lot

Three contiguous parcels offer a flexible commercial development footprint with public water service.

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Corner Commercial Land Parcel
Corner Commercial Land Parcel

288 27 Road, Grand Junction, CO 81503

$459,000
2.81 AC lot

Vacant MU-2 land at 27 Road and Unaweep, near schools, parks, shopping centers, grocery retailers, bike paths, and bus routes.

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Orchard Mesa Commercial Property
Orchard Mesa Commercial Property

2706 Highway 50, Grand Junction, CO 81503

$565,000
1,440 sqft 0.60 AC lot

Turnkey commercial property with drive-thru, high visibility, and expansion potential.

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Commercial Land Near Gas Station
Commercial Land Near Gas Station

32190 Willow Bend Road, Whitewater, CO 81527

$157,500
1.54 AC lot

MU-C zoning places this Highway 50 parcel beside the Golden Gate Gas Station.

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Quick-Service Restaurant Building
Quick-Service Restaurant Building

2878 North Ave, Grand Junction, CO 81501

$1,685,000
3,173 sqft

Built in 2013 with a fully equipped commercial kitchen on a high-profile corner lot near major retail.

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MU-1 Commercial Development Site
MU-1 Commercial Development Site

511 30 Road, Grand Junction, CO 81504

$305,000
0.44 AC lot

Improved lot with curbs, drainage, sidewalks, and access to public water.

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Mixed-Use Development Land with Shop
Mixed-Use Development Land with Shop

2379 G Rd, Grand Junction, CO 81505

$2,500,000
4,400 sqft 4.58 AC lot

4.58-acre fenced site with a ground-floor shop and small office, plus a mezzanine apartment shell.

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Highway Frontage Commercial Land
Highway Frontage Commercial Land

945 Dominguez Avenue, Grand Junction, CO 81503

$950,000
0.60 AC lot

The site has C-1 zoning, installed utilities, existing buildings, and established access points.

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Flex Space with Overhead Door
Flex Space with Overhead Door

1048 Independent Avenue #A105, Grand Junction, CO 81505

$377,728
1,664 sqft

Office and warehouse areas support contractor, e-commerce, and distribution operations.

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MU-2 Commercial Land
MU-2 Commercial Land

I-70 Business Loop, Grand Junction, CO 81504

$365,000
2.55 AC lot

City-annexed parcel near Walmart and Central High School with public water listed.

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Mesa County, CO Commercial Real Estate Market Trends and Statistics

Explore 573 commercial real estate for sale in Mesa County, CO, showcased through 573 active listings on our real estate platform. These investment opportunities span a total of 2,314,374 square feet of properties for sale, with an estimated market value of $535,572,876.

Sale prices for business properties in Mesa County, CO start at $60,000, averaging $1,242,628, and reaching up to $12,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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