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    Mesa County, CO Office Spaces for Lease

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    Denver, CO Colorado Springs, CO Boulder, CO
    183 results
    Retail Space on High-Traffic Avenue
    $1,275/Mo
    19,418 SF
    Retail Space on High-Traffic Avenue

    2851 1/2 North Avenue, Grand Junction, CO 81501

    1,275 SF retail space with high visibility and traffic.
    • High‑traffic location on North Avenue with approximately 22,000 vehicles per day.
    • Flexible, open 1,275 SF floor plan suitable for retail, service, office, or medical use.
    • Strong storefront visibility and signage opportunities.
    • Convenient paved parking for customers and staff.
    • Located in an established neighborhood strip center.
    Updated: May 22
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    Move-In Ready Mixed-Use Space
    $6,395/Mo
    3,070 SF
    Move-In Ready Mixed-Use Space

    879 Struthers Avenue, Grand Junction, CO 81501

    Light, bright commercial space with quality finishes, LED lighting, and two separate entrances for flexible front-door access.
    • Prime location near Las Colonias Amphitheatre and the Riverfront Trail in a rapidly developing area.
    • Flexible C‑2 zoning allows for office, retail, or flex space configurations.
    • Move‑in ready with quality finishes, LED lighting, and window blinds.
    • Two separate entrances provide flexible traffic flow.
    • Convenient access to I‑70B, Highway 50, and downtown Grand Junction.
    Updated: Apr 15
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    Premium Office Suite in Grand Junction
    $1,631/Mo
    29,340 SF
    Premium Office Suite in Grand Junction

    Move-in-ready 1,450 sq. ft. office suite for rent.

    2829 North Avenue, Grand Junction, CO 81501

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    Versatile Commercial Property in Grand Junction
    $6,500/Mo
    3,928 SF
    Versatile Commercial Property in Grand Junction

    Adaptable commercial space with office, shop, and yard in Grand Junction.

    2724 S Highway 50, Grand Junction, CO 81503

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    Retail or Office Sublet Suite
    $1,700/Mo
    9,418 SF
    Retail or Office Sublet Suite

    Suite in Village Square Shopping Center with dedicated access and strong visibility, suited for office or service use with minor build-out.

    2695 Patterson Road, Grand Junction, CO 81506

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    Medical Office Suite with Exam Rooms
    $15,240/Mo
    11,613 SF
    Medical Office Suite with Exam Rooms

    Lease-ready medical space offers exam rooms, physician offices, and ample waiting area with off-street parking.

    1035 Wellington Avenue, Grand Junction, CO 81501

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    Professional Office Suites with Underground Parking
    $3,385/Mo
    37,734 SF
    Professional Office Suites with Underground Parking

    Three approved professional office units with convenient access and parking, including reserved underground spaces.

    360 W Park Drive, Grand Junction, CO 81505

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    Professional Office Suites with Underground Parking
    $2,500/Mo
    37,734 SF
    Professional Office Suites with Underground Parking

    Three professional office units with ample parking options, including underground reserved spaces, available with long-term lease terms.

    360 W Park Drive, Grand Junction, CO 81505

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    Retail/Office Corner Suite with Parking
    $2,340/Mo
    18,559 SF
    Retail/Office Corner Suite with Parking

    A horizon-facing corner unit with expansive windows, private restroom, and front and rear entry for flexible retail or office use.

    759 Horizon Drive, Grand Junction, CO 81506

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    Turn-Key Restaurant Suite
    $2,000/Mo
    15,970 SF
    Turn-Key Restaurant Suite

    Turn-key suite with dedicated prep area and flexible indoor/outdoor seating on a high-visibility Highway 50 corridor.

    230 Lynwood Street, Grand Junction, CO 81503

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    Medical Office Suite with Private Rooms
    $3,803/Mo
    78,239 SF
    Medical Office Suite with Private Rooms

    Main-level medical suite with a large reception area, four private exam or office rooms, and back door access.

    3150 N 12th Street, Grand Junction, CO 81506

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    Warehouse with Office & Yard
    $3,500/Mo
    9,932 SF
    Warehouse with Office & Yard

    Climate-controlled warehouse plus flexible office and secure yard setup for efficient logistics and on-site operations.

    2375 Leland Avenue, Grand Junction, CO 81505

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    Office-Warehouse Condo Suite
    $2,150/Mo
    1,280 SF
    Office-Warehouse Condo Suite

    Climate-controlled flex-style condo with office amenities and a 12' overhead door for efficient loading and client-ready space.

    802 1st Avenue, Grand Junction, CO 81501

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    Office-Warehouse Condo Unit
    $2,150/Mo
    1,304 SF
    Office-Warehouse Condo Unit

    A climate-controlled condo with office amenities and convenient loading access for businesses that need both work and storage.

    802 1st Avenue, Grand Junction, CO 81501

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    Office-Warehouse Condo Unit
    $2,150/Mo
    1,304 SF
    Office-Warehouse Condo Unit

    Climate-controlled office and warehouse layout with a 12' overhead door for efficient loading and a private work suite.

    802 1st Avenue, Grand Junction, CO 81501

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    Retail-Office Suite at Shopping Center
    $1,315/Mo
    81,000 SF
    Retail-Office Suite at Shopping Center

    Move-in-ready suite with private offices and flexible layout in a high-traffic retail center.

    3210 I-70 Business Loop, Clifton, CO 81520

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    Retail and Medical Courtyard Space
    $1,135/Mo
    54,316 SF
    Retail and Medical Courtyard Space

    Anchored by an expanding tenant lineup, the space offers strong highway frontage, visibility, and convenient front parking.

    2148 Broadway, Grand Junction, CO 81507

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    High-Visibility Retail and Medical Space
    $2,005/Mo
    54,316 SF
    High-Visibility Retail and Medical Space

    Fronting Highway 340 with prominent parking and landscaped walkways, positioned within Monument Village Shopping Center.

    2148 Broadway, Grand Junction, CO 81507

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    Brand-New Finished Office Suites
    $3,000/Mo
    37,734 SF
    Brand-New Finished Office Suites

    Three professional office units with easy access and customer and employee parking, including underground reserved spaces.

    360 W Park Drive, Grand Junction, CO 81505

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    Upgraded Medical Office Suite
    $3,540/Mo
    2,469 SF
    Upgraded Medical Office Suite

    Move-in ready suite with eight offices, conference and break room, plus upgraded reception and ample off-street parking.

    2646 Patterson Road, Grand Junction, CO 81506

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    Office Condominium Suite
    $1,950/Mo
    1,110 SF
    Office Condominium Suite

    Well-appointed office suite with multiple offices, reception area, and conference/work space, ideal for professional teams.

    627 24 1/2 Road, Grand Junction, CO 81505

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    Prime Retail/Office Suite
    $1,341/Mo
    18,559 SF
    Prime Retail/Office Suite

    Front-and-rear access with massive retail windows, ample parking, and tenant improvements available.

    759 Horizon Drive, Grand Junction, CO 81506

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    Medical Office Suite with Basement
    $5,000/Mo
    3,000 SF
    Medical Office Suite with Basement

    Built-out medical office with off-street parking, strong signage visibility, and a large unfinished basement for storage or expansion.

    1660 North Avenue, Grand Junction, CO 81501

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    Office Condo with Elevated Stage
    $6,000/Mo
    5,846 SF
    Office Condo with Elevated Stage

    Flexible commercial condo with private offices, meeting rooms, and a stage-ready main area for gatherings and presentations.

    2938 North Avenue, Grand Junction, CO 81504

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    Mesa County, CO Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Mesa County, CO with 183 listings featured on our commercial real estate exchange. The current inventory includes 2,789,930 square feet of properties with an estimated lease value of $278,593.

    Estimated lease rates for Office Spaces in Mesa County, CO begin at $0.55 SF/Yr, with an average of $1,844 /Mo and extend to $83,000.
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