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    Mesa County, CO Mixed-use Properties for Sale

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    Denver, CO Colorado Springs, CO Fort Collins, CO
    11 results
    Grand Junction Commercial Development Opportunity
    $940,000
    3,520 SF

    Grand Junction Commercial Development Opportunity

    2718 Patterson Road, Grand Junction, CO 81506

    Commercial office, 4-plex on 0.89 acres with development potential.

    • Great potential development opportunity with MU‑1 zoning.
    • Located directly off Patterson Rd with high traffic counts.
    • Strong investment opportunity with existing income from Commercial Office and 4plex.
    • Large lot size of 0.89 Acres.
    • Includes both a Commercial Office (Modular at 1440 SF) and a 4plex (3520 SF).
    Updated: Nov 19, 2025
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    Mixed-Use Investment with Office
    $990,000
    3,520 SF

    Mixed-Use Investment with Office

    2718 Patterson Road, Grand Junction, CO 81506

    A 4-plex plus modular commercial office creates income with redevelopment and pad-site potential.

    • 4‑plex plus a commercial office modular (1440 SF) on Patterson Road near 12th St City Market
    • Sits on 0.89 acres and is zoned MU‑1, with commercial and multi‑family uses allowed
    • Commercial Comp Plan future land use and directly off Patterson Rd
    • Modular/commercial office includes appliances such as dishwasher, electric range/oven, disposal, and refrigerator
    • Heating includes natural gas and hot water (heating); roof is composition/asphalt
    Updated: Nov 19, 2025
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    Palisade Mixed-Use Zoned Land
    $1,100,000
    3.94 Acres

    Palisade Mixed-Use Zoned Land

    Mixed-use land in Palisade, near I-70 and Highway 6.

    602 Elberta Avenue, Palisade, CO 81526
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    Commercial Flex Building with Residence
    $649,000
    4,200 SF

    Commercial Flex Building with Residence

    Versatile commercial flex building with residential home in downtown.

    321 Pitkin Ave, Grand Junction, CO 81501
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    Grand Junction Mixed-Use Development Opportunity
    $149,000
    0.37 Acres

    Grand Junction Mixed-Use Development Opportunity

    0.37 acres in central location with mixed-use zoning.

    302 W Grand Avenue, Grand Junction, CO 81501
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    Cleared Mixed-Use Development Lot
    $249,000
    0.07 Acres

    Cleared Mixed-Use Development Lot

    Cleared lot with mixed-use allowance for a business below and a private loft or apartment above.

    125 E 1st Street, Palisade, CO 81526
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    Orchard Mesa Commercial Property
    $625,000
    1,440 SF

    Orchard Mesa Commercial Property

    Turnkey commercial property with drive-thru, high visibility, and expansion potential.

    2706 HWY 50, Grand Junction, CO 81503
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    Fruita Mixed-Use Development Opportunity
    $500,000
    0.55 Acres

    Fruita Mixed-Use Development Opportunity

    Classic bungalow on 0.55 acres with development potential.

    551 East Grand Avenue, Fruita, CO 81521
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    Sherwood Park Leased Units Building
    $799,000
    4,590 SF

    Sherwood Park Leased Units Building

    Leased units in updated building with private parking lot.

    403 Kennedy Ave, Grand Junction, CO 81501
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    Shop with Office and Yard
    $425,000
    1,296 SF

    Shop with Office and Yard

    Downtown Grand Junction shop with office, yard, and development potential.

    1162 Ute Ave, Grand Junction, CO 81501
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    Collbran Mixed-Use Investment Opportunity
    $395,000
    2,439 SF

    Collbran Mixed-Use Investment Opportunity

    Four-unit property with residential and commercial spaces in Collbran, Colorado.

    1004 High Street, Collbran, CO 81624
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    Based on your search, we've compiled 46 Potential Opportunities for your consideration. Besides 11 Active listings in Mesa County, CO, we suggest exploring several alternatives: similar 31 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Grand Junction Commercial Development Parcel
    $600,000
    0.80 Acres

    Grand Junction Commercial Development Parcel

    Prime 0.80-acre commercial land parcel in Grand Junction, Colorado.

    3145 E 1/2 Road lot: 3, Grand Junction, CO 81504
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    Grand Junction Commercial Development Parcel
    $695,000
    1.40 Acres

    Grand Junction Commercial Development Parcel

    1.4 acre commercial land parcel in Grand Junction, Colorado.

    3145 E 1/2 Road lot: 4, Grand Junction, CO 81504
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    49+ Acres Mixed Use Land
    $4,750,000
    49.12 Acres

    49+ Acres Mixed Use Land

    49+ acres of mixed-use development ground near I-70.

    699 29 Road, Grand Junction, CO 81504
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    Grand Junction Commercial Land Parcel
    $950,000
    0.90 Acres

    Grand Junction Commercial Land Parcel

    Commercial land parcel in high-traffic area, Grand Junction, Colorado.

    28 1/4 Road, Grand Junction, CO 81506
    View details

    Off-Market Properties in Mesa County, CO

    Consider similar Off-Market properties in Mesa County, CO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2464 Hwy 6th And 50
    STORE/OFFICE (MIXED USE)
    206,585 SF Lot: 18.98 Acres
    Estimated value
    $19,030,000

    2464 Hwy 6th And 50, Grand Junction, CO 81505-1138

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    2474 Hwy 6th And 50
    STORE/OFFICE (MIXED USE)
    7,389 SF Lot: 1.33 Acres
    Estimated value
    $985,000

    2474 Hwy 6th And 50, Grand Junction, CO 81505-1145

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    2478 Hwy 6th And 50
    STORE/OFFICE (MIXED USE)
    8,194 SF Lot: 1.21 Acres
    Estimated value
    $1,075,000

    2478 Hwy 6th And 50, Grand Junction, CO 81505-1122

    View details
    644 Nn Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.76 Acres
    Estimated value
    $745,000

    644 Nn Ave, Grand Junction, CO 81501-7544

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    2536 Rimrock Ave
    STORE/OFFICE (MIXED USE)
    15,300 SF Lot: 1.94 Acres
    Estimated value
    $1,920,000

    2536 Rimrock Ave, Grand Junction, CO 81505-8669

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    2504 Hwy 6th And 50
    STORE/OFFICE (MIXED USE)
    9,801 SF Lot: 4.09 Acres
    Estimated value
    $1,255,000

    2504 Hwy 6th And 50, Grand Junction, CO 81505-7170

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    2502 Hwy 6th And 50
    STORE/OFFICE (MIXED USE)
    17,544 SF Lot: 2.01 Acres
    Estimated value
    $2,210,000

    2502 Hwy 6th And 50, Grand Junction, CO 81505-4501

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    225 Grand Ave
    STORE/OFFICE (MIXED USE)
    Lot: 0.13 Acres
    Value Estimation by Request

    225 Grand Ave, Grand Junction, CO 81501

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    675 23 1/2 Rd
    Multifamily properties
    60,000 SF Lot: 1.50 Acres
    Value Estimation by Request

    675 23 1/2 Rd, Grand Junction, CO 81505

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    2600 Riverside Pkwy
    Mixed-use properties
    Lot: 1.61 Acres
    Value Estimation by Request

    2600 Riverside Pkwy, Grand Junction, CO 81501

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    3526 Front St
    Mixed-use properties
    1,344 SF Lot: 6.87 Acres
    Value Estimation by Request

    3526 Front St, Palisade, CO 81526

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    2324 Highway 6 And 50
    Mixed-use properties
    1,452 SF Lot: 2.89 Acres
    Value Estimation by Request

    2324 Highway 6 And 50, Grand Junction, CO 81505

    View details
    1915 I-70Bl
    Distribution properties
    9,000 SF Lot: 0.37 Acres
    Value Estimation by Request

    1915 I-70Bl, Grand Junction, CO 81501

    View details

    Mesa County, CO Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 42 mixed-use properties for sale in Mesa County, CO, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 21,005 square feet of properties for sale, with an estimated market value of $4,823,000.

    Sale prices for multi use buildings in Mesa County, CO start at $395,000, averaging $689,000, and reaching up to $990,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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