Moncks Corner, SC Commercial Real Estate for Lease

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Summerville, SC Ladson, SC Goose Creek, SC N Charleston, SC North Charleston, SC Hanahan, SC Wando, SC Ridgeville, SC

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Updated: Mar 6

Moncks Corner Medical Office Sublease

422 Drive In Lane, Moncks Corner, SC 29461

$22 SF/Yr

7,490 sqft

Free‑standing ±7,490 SF Class A medical office building.
Ideal for various medical uses (walk‑in clinic, orthodontist, infusion center, dentist, etc.) or another dialysis clinic.
Sublease until 1/31/2036.
Located in Moncks Corner's developing retail district near Walmart Supercenter and Tractor Supply Co.
Ample parking along the sides and rear.

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Updated: Nov 24, 2025

Medical Office Space Available

3508 S Live Oak Dr, Moncks Corner, SC

$32 SF/Yr

8,000 sqft

8,000 SF medical office space available.
Located on the third floor.
Lease rate is $24/SF plus $8 CAM.
Coastal Cardiology occupies the second floor.
Contact Bob Glover, CCIM at 843‑572‑0000.

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Moncks Corner Downtown Office Space

337 E Main St, Moncks Corner, SC

$16 SF/Yr

1,000 sqft

Prominent building in downtown Moncks Corner with flexible zoning.

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Moncks Corner Warehouse for Lease

200 Kelly Lane, Moncks Corner, SC 29461

Contact for pricing

285,485 sqft

285,485 SF warehouse on 43.28 AC for lease.

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Highway 52 Industrial Land

1930 Highway 52, Moncks Corner, SC

$3,000/Mo

High-visibility industrial land for lease near Downtown Moncks Corner.

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Moncks Corner Commercial Property Available

447 N Highway 52, Moncks Corner, SC 29461

$95,000 SF/Yr

Commercial property available for rent in Moncks Corner, SC.

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Moncks Corner Flex Space For Lease

2700 U.S. 52, Moncks Corner, SC 29461

$14 SF/Yr

10,960 sqft

Versatile flex space with covered storage and ample parking.

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Grocery-Anchored Retail Outparcels

1613 South Live Oak Drive, Moncks Corner, SC 29461

Contact for pricing

Two grocery-anchored outparcels with rough grading, utilities stubs, and stormwater in place for common retail development.

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Moncks Corner Commercial Space For Lease

2700 US-52, Moncks Corner, SC 29461

$14 SF/Yr

10,960 sqft

Commercial lease featuring indoor space, outdoor storage, and ample parking.

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Grocery Store Opportunity

110 US 52, Moncks Corner, SC

Contact for pricing

49,065 sqft

49,065 SF grocery box available for lease.

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Based on your search, we've compiled 39 Potential Opportunities for your consideration. Besides 10 Active listings in Moncks Corner, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 25 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Flex Space with Rear Lay-Down Yard

806-A Beckham Lane, Summerville, SC 29483

Contact for pricing

3,400 sqft

Flex building with office buildout, 16’ clear warehouse, and a rear lay-down yard sized to maneuver tractor trailers.

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Retail Endcap with Drive-Thru

1769 State Rd, Summerville, SC 29486

$42 SF/Yr

New retail endcap with drive-thru and strong State Road visibility, positioned to serve the growing Cane Bay market.

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Retail Ground Lease Pad on Hwy Frontage

1761-1769 State Rd, Summerville, SC 29486

$140,000 SF/Yr

High-ground parcel on a major state road with one remaining pad and strong visibility across from Publix.

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Commercial Development Opportunity

1601 STATE RD, Summerville, SC

$38 SF/Yr

11,900 sqft

Proposed commercial development with high visibility and roadway frontage.

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Similar Spaces for Sale in Moncks Corner, SC

Consider Similar Space for Sale. We found 25 Spaces matching your search parameters.

New Commercial Facility on 5 Acres

2350 Cooper Store Rd, Moncks Corner, SC 29461

$1,750,000

8,825 sqft 5.00 AC lot

New 8,825 SF facility on 5 acres in Moncks Corner.

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Cleared Lot on Highway 17-A

231 S Live Oak Drive, Moncks Corner, SC 29461

$200,000

0.47 AC lot

Cleared 0.47 acre lot with road frontage in Moncks Corner.

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Moncks Corner Strip Center Investment

1010 Old Highway 52, Moncks Corner, SC 29461

$1,300,000

8,000 sqft

Fully leased strip center in high-traffic Moncks Corner location.

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Wooded Industrial Development Land

Mount Pleasant Drive, Moncks Corner, SC 29461

$1,500,000

21.00 AC lot

21+/- acres of mostly level, timbered land with substantial road frontage for flexible industrial or mixed-use development.

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Moncks Corner Commercial Land Available

2086 S Live Oak Drive, Moncks Corner, SC 29461

$484,000

2.76 AC lot

2.76 acres of commercial land for sale in Moncks Corner.

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Moncks Corner Land For Sale

220 N Highway 52, Moncks Corner, SC 29461

$395,000

5.00 AC lot

5 acres on Hwy 52, Moncks Corner. Priced to sell.

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Moncks Corner Land For Sale

Umbria Road, Moncks Corner, SC 29461

$89,000

2.60 AC lot

2.6 acre commercial land available in Moncks Corner, SC.

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Vacant Lot in Moncks Corner

Yaremich Drive, Moncks Corner, SC 29461

$85,000

1.00 AC lot

One-acre vacant lot near Lake Moultrie, Summerville, and Moncks Corner.

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Moncks Corner Commercial Land Available

0 Drive In Lane, Moncks Corner, SC

$1,250,000

8.00 AC lot

Approximately 8 acres of commercial land for sale.

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Moncks Corner Office For Sale

219 W Main St, Moncks Corner, SC 29461

$350,000

1,441 sqft

Office space available in Moncks Corner, South Carolina.

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226 Acres on Cooper River

Point Comfort, Moncks Corner, SC 29461

$1,075,000

226.13 AC lot

226-acre sportsman's paradise near Charleston with conservation easement.

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85 Acres on Cooper River

Point Comfort, Moncks Corner, SC 29461

$775,000

85.16 AC lot

85-acre sportsman's paradise near Charleston with Cooper River frontage.

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311 Acres on Cooper River

Point Comfort, Moncks Corner, SC 29461

$1,850,000

311.29 AC lot

Historic land with conservation easement, ideal for sportsman's retreat.

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Moncks Corner Land For Sale

605 Main Street, Moncks Corner, SC 29461

$1,350,000

3.90 AC lot

3.9 acre commercial land available in Moncks Corner, SC.

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Moncks Corner, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Moncks Corner, SC with 10 listings featured on our commercial real estate exchange. The current inventory includes 38,410 square feet of properties with an estimated lease value of $98 SF/Yr.

Estimated lease rates for Commercial real estate in Moncks Corner, SC begin at $14 SF/Yr, with an average of $19.60 SF/Yr and extend to $32 SF/Yr.

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