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    South Carolina Commercial Real Estate for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    Showing 24 of 3,121 listings
    Former Restaurant on Decker Boulevard
    $22 SF/Yr
    4,320 SF
    Former Restaurant on Decker Boulevard

    4,320 SF former restaurant with drive-thru on 1.13 AC.

    2600 Decker Boulevard, Columbia, SC 29206

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    Retail Space in Goose Creek
    $19 SF/Yr
    7,053 SF
    Retail Space in Goose Creek

    End-cap retail space in a well-located shopping center.

    428 Red Bank Rd, Goose Creek, SC 29445

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    Myrtle Beach Office Space For Lease
    $16 SF/Yr
    4,500 SF
    Myrtle Beach Office Space For Lease

    Office space for lease near Myrtle Beach's financial corridor.

    601 19th Avenue N, Unit 202B, Myrtle Beach, SC 29577

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    Historic Office Space in Fort Mill
    $22 SF/Yr
    2,138 SF
    Historic Office Space in Fort Mill

    Exceptional leasing opportunity in downtown Fort Mill's thriving commercial district.

    100 Main St, Fort Mill, SC 29715

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    Office Space in Vista District
    $23 SF/Yr
    6,782 SF
    Office Space in Vista District

    Office spaces for lease in Columbia's popular Vista district.

    500 Taylor Street, Columbia, SC 29201

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    Myrtle Beach Office Space Available
    $16 SF/Yr
    4,500 SF
    Myrtle Beach Office Space Available

    Office space for lease near Myrtle Beach's financial corridor.

    601 19th Avenue N,Unit 202A, Myrtle Beach, SC 29577

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    Dorchester Pavilion
    $30 SF/Yr
    Dorchester Pavilion

    Charleston, SC Restaurant/Medical/Retail Space

    8636 Dorchester Rd, North Charleston, SC 29420

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    North End Office Spaces
    $22 SF/Yr
    4,335 SF
    North End Office Spaces

    North end office spaces for lease in Hilton Head.

    100 Exchange Street, Hilton Head Island, SC 29926

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    West Columbia Office/Medical Suite
    $18 SF/Yr
    12,000 SF
    West Columbia Office/Medical Suite

    Office/medical suite for lease near Lexington Medical Hospital.

    3618 Sunset Blvd., West Columbia, SC 29169

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    Retail Space Next to Fitness
    $17 SF/Yr
    14,384 SF
    Retail Space Next to Fitness

    Retail space available next to Crunch Fitness on W Butler Road.

    207 West Butler Road, Mauldin, SC 29662

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    Office Space For Rent
    $20 SF/Yr
    15,000 SF
    Office Space For Rent

    Office suites available in Columbia, between Downtown and Forest Acres.

    3321 Forest Drive, Columbia, SC 29204

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    Historic Arcade Mall Retail Space
    $600/Mo
    39,320 SF
    Historic Arcade Mall Retail Space

    Historic indoor shopping center with high-end finishes in downtown Columbia.

    1332 Main St, Columbia, SC 29201

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    Spartanburg Automotive Shop For Lease
    $11 SF/Yr
    2,000 SF
    Spartanburg Automotive Shop For Lease

    2,000 SF automotive shop or light industrial space available.

    51A Dexter Rd, Spartanburg, SC 29303

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    Downtown Greenville Retail Space Available
    $30 SF/Yr
    3,370 SF
    Downtown Greenville Retail Space Available

    Retail space for lease in downtown Greenville, South Carolina.

    942 S Main Street, Greenville, SC 29601

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    Spacious Office and Medical Suite
    $29 SF/Yr
    8,988 SF
    Spacious Office and Medical Suite

    8,988 SF professional office/medical suite in Fort Mill, SC.

    345 Patricia Lane, Fort Mill, SC 29708

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    Retail Space Near Walmart
    $26 SF/Yr
    1,200 SF
    Retail Space Near Walmart

    Retail space available February 2026 near Walmart Supercenter.

    1211 Retail Row, Hartsville, SC 29550

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    Rock Hill Flex Space Warehouse
    $16 SF/Yr
    Rock Hill Flex Space Warehouse

    Versatile, customizable, climate-controlled flex space and warehouse units available for rent.

    2150 Cherry Road, Rock Hill, SC 29732

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    Rock Hill Coworking Space Available
    $200 SF/Yr
    12,460 SF
    Rock Hill Coworking Space Available

    Flexible coworking and dedicated desk space in vibrant Knowledge Park.

    116 E Main St, Suite 201, Rock Hill, SC 29730

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    Westbury Park Class A Office
    $27 SF/Yr
    2,930 SF
    Westbury Park Class A Office

    Class A office space for lease in Westbury Park.

    12 Arley Way, Ste 201, Bluffton, SC 29910

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    New Lexington County Office Space
    $23 SF/Yr
    6,500 SF
    New Lexington County Office Space

    Office space for lease in a growing Lexington County location.

    120 Brookside Parkway, Lexington, SC 29072

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    New Retail/Office/Medical Space Available
    $35 SF/Yr
    8,450 SF
    New Retail/Office/Medical Space Available

    New retail, office, or medical spaces available in NE Columbia.

    565 Spears Creek Church Road, Elgin, SC 29045

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    Retail Space with Outdoor Patio
    $32 SF/Yr
    1,211 SF
    Retail Space with Outdoor Patio

    Prime retail suite with patio in high-traffic Fort Mill.

    400 N Dobys Bridge Rd, Fort Mill, SC 29715

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    Office Space in Business Park
    $3,000/Mo
    2,175 SF
    Office Space in Business Park

    Office space with high-end finishes in a business park.

    386 Spanish Wells Rd, Unit B-3, Hilton Head Island, SC 29926

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    Office Suite in West Columbia
    $15 SF/Yr
    9,890 SF
    Office Suite in West Columbia

    Office suite for lease near downtown Columbia and Lexington Medical Center.

    1523 Sunset Blvd., West Columbia, SC 29169

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