Seneca, SC Commercial Real Estate for Sale

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Seneca Commercial Building For Sale
Updated: Jan 7
Seneca Commercial Building For Sale

518 W N 1st Street, Seneca, SC 29678

$1,695,000
8,000 sqft 1.01 AC lot
High‑traffic location in a growing area of Seneca, SC.
All brick/concrete building construction.
Existing tenants occupy approximately 8000 sqft, providing immediate income.
Over 7000 sqft available for new tenant or owner‑occupancy.
Warehouse‑style construction with 16‑foot ceilings.
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518 W N 1st Street, Seneca, SC 29678

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Two-Lot Live-Work Development Land
Updated: Jun 30
Two-Lot Live-Work Development Land

Tract 18/19 S Walnut Street, Seneca, SC 29678

$265,000
2.20 AC lot
Unique 2‑lot package on S. Walnut St: 1.49‑acre residential lot plus a .71‑acre tract next door.
Tract 18 is zoned residential; tract 19 is zoned commercial (buyer to confirm rezoning availability if desired).
Tract 18 utilities include power setup, water, and two septic systems (public remarks also reference “Tract 18 with 149 acres”—verify).
Owner will not separate the tracts—purchase includes both lots.
Location is less than 5 minutes from downtown Seneca’s retail/dining district and a short hop to Clemson University.
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Unrestricted Subdividable Land Parcel
Unrestricted Subdividable Land Parcel

12051 N Radio Station Road, Seneca, SC 29678

$799,900
22.18 AC lot

Unrestricted general-use land offering 22.18 acres and subdividing potential near Seneca.

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Seneca Retail Building For Sale
Seneca Retail Building For Sale

12020 North Radio Station Road, Seneca, SC 29678

$1,399,999
12,000 sqft 2.42 AC lot

12,000 SF building with conversion potential in Seneca, SC.

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General Commercial Retail/Office Building
General Commercial Retail/Office Building

615 W N 1st Street, Seneca, SC 29678

$199,900
0.23 AC lot

Open floor plan with two bathrooms and a side storage building, zoned General Commercial in Seneca.

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Commercial Lot Near Wells Highway
Commercial Lot Near Wells Highway

Corner of Wells Hwy. & Return Church Rd. Highway, Seneca, SC 29678

$395,000
0.99 AC lot

0.99-acre commercial lot with high visibility and easy access.

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Office Building with Road Frontage
Office Building with Road Frontage

11081 N Radio Station Road, Seneca, SC 29678

$217,000
0.63 AC lot

Single-building office asset just outside Seneca city limits with substantial road frontage on Radio Station Road.

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Two Warehouses Near Clemson
Two Warehouses Near Clemson

306 By Pass 123, Seneca, SC

$490,000
9,650 sqft 1.09 AC lot

Two warehouse buildings totaling 9,650 SF on one acre.

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Commercial Land Near Highway 123
Commercial Land Near Highway 123

1.8 Acres Rochester Highway, Seneca, SC 29672

$699,000
1.80 AC lot

Unrestricted 1.8-acre commercial land near major retailers and highways.

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Established Hibachi Restaurant for Sale
Established Hibachi Restaurant for Sale

1510 Blue Ridge Boulevard, Seneca, SC 29672

$219,000

Turnkey Hibachi restaurant with existing lease and equipment included.

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NNN Bank Building
NNN Bank Building

1313 Sandifer Boulevard, Seneca, SC 29678

$2,049,000

For sale NNN bank building with corporate ABS structure in Seneca, SC.

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Commercial Building with Open Plan
Commercial Building with Open Plan

615 W North 1st St, Seneca, SC 29678

$214,900

Own a tenant-occupied commercial building with an open floor plan, two bathrooms, and a recently installed HVAC unit.

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The Clemson Commercial Lot
The Clemson Commercial Lot

189 Seneca Creek Road, Seneca, SC 29678

$175,000
84,942 sqft 1.95 AC lot

1.95 Acres Land, The Clemson Commercial Lot

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60 Acres Land 101 Friendship Road Tract B
60 Acres Land 101 Friendship Road Tract B

101 Friendship Road, Seneca, SC 29678

$1,000,000
2,613,600 sqft 60.00 AC lot

A convenient 60 acres to everything Clemson

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Brick Concrete Warehouse Flex Building
Brick Concrete Warehouse Flex Building

518 W North 1st St, Seneca, SC 29678

$1,695,000

All-brick warehouse flex space with 16-foot ceilings and existing tenants, offering room for another tenant or owner-occupancy.

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Prime Commercial Acreage For Sale
Prime Commercial Acreage For Sale

1018 E. North 1st Street, Seneca, SC 29678

$3,500,000
4.33 AC lot

4.3 acres in Seneca, SC, ideal for retail or hospitality.

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Oconee County Land For Sale
Oconee County Land For Sale

8006 Keowee School Road, Seneca, SC 29672

$619,943
24.70 AC lot

24.7 acres of unrestricted land near Lake Keowee.

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Commercial Land on Clemson Boulevard
Commercial Land on Clemson Boulevard

10149 & 10161 Clemson Blvd, Seneca, SC 29678

$1,400,000
3.94 AC lot

3.94 acres of commercial land with road frontage.

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Freestanding Office Building
Freestanding Office Building

631 By Pass 123, Seneca, SC 29678

Contact for pricing

For sale office building at 631 By Pass 123, offering a straightforward setup for professional tenants.

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Commercial Land on Radio Station Road
Commercial Land on Radio Station Road

11081 N Radio Station Road, Seneca, SC 29678

$250,000
0.63 AC lot

Commercial land with building on busy Radio Station Road.

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Corner Lot in Seneca
Corner Lot in Seneca

911 E. North 1st Street Street, Seneca, SC 29678

$325,000
1.29 AC lot

1.29 acre corner lot zoned for commercial use.

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Land Near Clemson University
Land Near Clemson University

Union Station Dr, Seneca, SC 29678

$350,000
6.54 AC lot

Land available near Clemson University, close to lakes.

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Unrestricted Commercial Land Near Highway
Unrestricted Commercial Land Near Highway

1.8 Acres Rochester Highway, Seneca, SC 29672

$699,000
1.80 AC lot

1.8 acres of unrestricted commercial land with high traffic count.

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Lake Keowee Acreage in Seneca
Lake Keowee Acreage in Seneca

45+/- Acres Knollwood Drive Unit Keowee I, Seneca, SC 29678

$2,250,000
45.00 AC lot

45+/- acres within Seneca city limits with utilities.

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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 24 Active Listings in Seneca, SC, we suggest to view alternatives - similar 48 Off-Market properties to explore as potential leads.

Seneca, SC Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Seneca, SC, showcased through 24 active listings on our real estate platform. These investment opportunities span a total of 2,728,192 square feet of properties for sale, with an estimated market value of $4,759,999.

Sale prices for business properties in Seneca, SC start at $175,000, averaging $951,999, and reaching up to $1,695,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 36K
Population Growth (5Y) +2.7%
Median Household Income $62,735
College Educated 31.9%

High-Yield Neighborhoods for Investment

Identify Seneca submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
29672 $559.2K
29678 $1.3M

Listings Trend

New vs delisted commercial listings in Oconee County

New Delisted

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