Add Listing
    Seneca, SC
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price
    $
    $

    Seneca, SC Commercial Real Estate for Sale

    Notify Me
    List
    Map
    Newry, SC West Union, SC Walhalla, SC
    30 results
    Seneca Commercial Building For Sale
    $1,695,000
    8,000 SF

    Seneca Commercial Building For Sale

    518 W N 1st Street, Seneca, SC 29678

    All brick/concrete building in Seneca, SC with tenant income.

    • High‑traffic location in a growing area of Seneca, SC.
    • All brick/concrete building construction.
    • Existing tenants occupy approximately 8000 sqft, providing immediate income.
    • Over 7000 sqft available for new tenant or owner‑occupancy.
    • Warehouse‑style construction with 16‑foot ceilings.
    Updated: Jan 7
    View details
    Seneca Land in Prime Location
    $49,900
    0.50 Acres

    Seneca Land in Prime Location

    S Fairplay Street, Seneca, SC 29678

    Buildable lot in downtown Seneca near lakes and amenities.

    • Prime downtown Seneca location, close to shopping and entertainment.
    • Large half‑acre lot, one of the largest in town.
    • Buildable, level, and mostly cleared land.
    • Utilities available at the street: sewer, water, and natural gas.
    • Conveniently located between Lake Hartwell and Lake Keowee.
    Updated: Apr 22
    View details
    Prime Commercial Land Opportunity
    $545,000
    2.65 Acres

    Prime Commercial Land Opportunity

    2.65-acre commercial parcel in high-growth area, ideal for development.

    1800 Sandifer Boulevard, Seneca, SC 29678
    View details
    Commercial Building in Seneca, SC
    $234,900
    0.23 Acres

    Commercial Building in Seneca, SC

    Commercial building with open floor plan suitable for retail/office/restaurant.

    615 W N 1st Street, Seneca, SC 29678
    View details
    Turn-Key Restaurant Franchise Opportunity
    $1,900,000
    0.78 Acres

    Turn-Key Restaurant Franchise Opportunity

    Turn-key national franchise restaurant with real estate for sale.

    1053 By Pass 123 Bypass, Seneca, SC 29678
    View details
    Seneca Retail Building For Sale
    $1,399,999
    12,000 SF

    Seneca Retail Building For Sale

    12,000 SF building with conversion potential in Seneca, SC.

    12020 North Radio Station Road, Seneca, SC 29678
    View details
    Commercial Lot Near Wells Highway
    $395,000
    0.99 Acres

    Commercial Lot Near Wells Highway

    0.99-acre commercial lot with high visibility and easy access.

    Corner of Wells Hwy. & Return Church Rd. Highway, Seneca, SC 29678
    View details
    Two Warehouses Near Clemson
    $490,000
    9,650 SF

    Two Warehouses Near Clemson

    Two warehouse buildings totaling 9,650 SF on one acre.

    306 By Pass 123, Seneca, SC
    View details
    Commercial Land on Radio Station Road
    $250,000
    0.63 Acres

    Commercial Land on Radio Station Road

    Commercial land with building on busy Radio Station Road.

    11081 N Radio Station Road, Seneca, SC 29678
    View details
    Seneca Retail Building For Sale
    $1,399,999
    12,000 SF

    Seneca Retail Building For Sale

    12,000 SF building with conversion potential in Seneca, SC.

    12020 N Radio Station Rd, Seneca, SC 29678
    View details
    Freestanding Office Building
    $250,000
    0.63 Acres

    Freestanding Office Building

    Original radio station facility offers strong road frontage and redevelopment flexibility for investors or business operators.

    11081 N Radio Station Road, Seneca, SC 29678
    View details
    Land with Highway Frontage
    $1,900,000
    102.70 Acres

    Land with Highway Frontage

    Commercial land with highway and state road frontage.

    125 Armstrong Road, Seneca, SC 29678
    View details
    Seneca Office Space For Sale
    $599,000
    2,400 SF

    Seneca Office Space For Sale

    Office space conveniently located off Bypass 123 in Seneca, SC.

    631 By Pass 123, Seneca, SC
    View details
    Downtown Seneca Buildable Lot
    $49,900
    0.50 Acres

    Downtown Seneca Buildable Lot

    Prime downtown location, buildable lot near shopping and lakes.

    00 S Fairplay St, Seneca, SC 29678
    View details
    Prime Commercial Acreage For Sale
    $3,500,000
    4.33 Acres

    Prime Commercial Acreage For Sale

    4.3 acres in Seneca, SC, ideal for retail or hospitality.

    1018 E. North 1st Street, Seneca, SC 29678
    View details
    Seneca Self-Storage Facility for Sale
    $3,000,000

    Seneca Self-Storage Facility for Sale

    Self-storage facility in Seneca, SC, available for purchase.

    420 Sitton Shoals Rd, Seneca, SC 29678
    View details
    The Clemson Commercial Lot
    $175,000
    84,942 SF

    The Clemson Commercial Lot

    1.95 Acres Land, The Clemson Commercial Lot

    189 Seneca Creek Road, Seneca, SC 29678
    View details
    Seneca Office Space For Rent
    Contact for pricing
    2,900 SF

    Seneca Office Space For Rent

    Office space in the heart of Seneca, ample parking.

    735 N Townville St, Seneca, SC
    View details
    Oconee County Land For Sale
    $619,943
    24.70 Acres

    Oconee County Land For Sale

    24.7 acres of unrestricted land near Lake Keowee.

    8006 Keowee School Road, Seneca, SC 29672
    View details
    60 Acres Land 101 Friendship Road Tract B
    $1,000,000
    2,613,600 SF

    60 Acres Land 101 Friendship Road Tract B

    A convenient 60 acres to everything Clemson

    101 Friendship Road, Seneca, SC 29678
    View details
    Commercial Land on Clemson Boulevard
    $2,000,000
    3.94 Acres

    Commercial Land on Clemson Boulevard

    3.94 acres of commercial land with road frontage.

    10149 & 10161 Clemson Blvd, Seneca, SC 29678
    View details
    Commercial Land Near Highway 123
    $699,000
    1.80 Acres

    Commercial Land Near Highway 123

    Unrestricted 1.8-acre commercial land near major retailers and highways.

    1.8 Acres Rochester Highway, Seneca, SC 29672
    View details
    Corner Lot in Seneca
    $325,000
    1.29 Acres

    Corner Lot in Seneca

    1.29 acre corner lot zoned for commercial use.

    911 E. North 1st Street Street, Seneca, SC 29678
    View details
    Automotive Shop Near Lake Keowee
    $900,000

    Automotive Shop Near Lake Keowee

    10-bay automotive shop, redevelopment potential for fast food.

    445 By Pass 123, Seneca, SC 29678
    View details

    Seneca, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Seneca, SC, showcased through 30 active listings on our real estate platform. These investment opportunities span a total of 5,433,134 square feet of properties for sale, with an estimated market value of $6,238,998.

    Sale prices for business properties in Seneca, SC start at $175,000, averaging $779,874, and reaching up to $1,399,999 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Demographics Overview

    Population 36K
    Population Growth (5Y) +2.7%
    Median Household Income $62,735
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Seneca submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    29672 $559.2K
    29678 $1.2M

    Need Help?

    Reach out if you need assistance with Realmo tools or have questions about your listings

    Browse Commercial real estate for Sale Near Seneca, SC

    Popular Searches in Seneca, SC

    Popular Categories

    Most Searched ZIP Codes in Seneca, SC

    • 29678
    • 29672

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!