Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Seneca, SC Commercial Real Estate for Sale

    List
    Map
    Columbia, SC Greenville, SC Aiken, SC
    30 results
    Commercial Building in Seneca, SC
    $249,900
    0.23 Acres

    Commercial Building in Seneca, SC

    615 W N 1st Street, Seneca, SC 29678

    Commercial building with open floor plan suitable for various businesses.

    • Commercial building in Seneca with versatile potential for retail, office, or restaurant use.
    • Features an open floor plan suitable for various business types.
    • Includes a storage building providing additional space.
    • Central heating and cooling ensure year‑round comfort.
    • Has two bathrooms.
    Updated: Apr 17
    View details
    Seneca Retail/Warehouse Opportunity
    $1,800,000
    1.01 Acres

    Seneca Retail/Warehouse Opportunity

    518 W N 1st Street, Seneca, SC 29678

    All brick/concrete building with existing tenants and expansion potential.

    • High‑traffic location in a growing area of Seneca, SC.
    • All brick/concrete building construction.
    • Existing tenants occupy approximately 8000 sqft, providing immediate income.
    • Over 7000 sqft available for new tenant or owner‑occupancy.
    • Warehouse‑style construction with 16‑foot ceilings.
    Updated: Jan 7
    View details
    Prime Commercial Land Opportunity
    $545,000
    2.65 Acres

    Prime Commercial Land Opportunity

    2.65-acre commercial parcel in high-growth area, ideal for development.

    1800 Sandifer Boulevard, Seneca, SC 29678
    View details
    Commercial Land in Seneca, SC
    $275,000
    2.50 Acres

    Commercial Land in Seneca, SC

    2.5-acre commercial lot in Seneca, ready for development.

    13000 S Radio Station Road, Seneca, SC 29678
    View details
    Turn-Key Restaurant Franchise Opportunity
    $1,900,000
    0.78 Acres

    Turn-Key Restaurant Franchise Opportunity

    Turn-key national franchise restaurant with real estate for sale.

    1053 By Pass 123 Bypass, Seneca, SC 29678
    View details
    Commercial Lot Near Wells Highway
    $395,000
    0.99 Acres

    Commercial Lot Near Wells Highway

    0.99-acre commercial lot with high visibility and easy access.

    Corner of Wells Hwy. & Return Church Rd. Highway, Seneca, SC 29678
    View details
    Two Warehouses Near Clemson
    $490,000
    9,650 SF

    Two Warehouses Near Clemson

    Two warehouse buildings totaling 9,650 SF on one acre.

    306 By Pass 123, Seneca, SC
    View details
    Seneca Retail Building For Sale
    $1,399,999
    12,000 SF

    Seneca Retail Building For Sale

    12,000 SF building with conversion potential in Seneca, SC.

    12020 North Radio Station Road, Seneca, SC 29678
    View details
    Seneca Automotive Service Property
    $125,000

    Seneca Automotive Service Property

    Automotive service property near downtown Seneca with four bays.

    919 E S 6th Street, Seneca, SC 29678
    View details
    Corner Lot in Seneca
    $325,000
    1.29 Acres

    Corner Lot in Seneca

    1.29 acre corner lot zoned for commercial use.

    911 E. North 1st Street Street, Seneca, SC 29678
    View details
    Prime Commercial Acreage For Sale
    $3,500,000
    4.33 Acres

    Prime Commercial Acreage For Sale

    4.3 acres in Seneca, SC, ideal for retail or hospitality.

    1018 E. North 1st Street, Seneca, SC 29678
    View details
    Commercial Property on Radio Station Rd
    $250,000
    0.63 Acres

    Commercial Property on Radio Station Rd

    Commercial property with road frontage, suitable for business location.

    11081 N Radio Station Road, Seneca, SC 29678
    View details
    Commercial Land on Radio Station Road
    $250,000
    0.63 Acres

    Commercial Land on Radio Station Road

    Commercial land with building on busy Radio Station Road.

    11081 N Radio Station Road, Seneca, SC 29678
    View details
    Seneca Retail Building For Sale
    $1,399,999
    12,000 SF

    Seneca Retail Building For Sale

    12,000 SF building with conversion potential in Seneca, SC.

    12020 N Radio Station Rd, Seneca, SC 29678
    View details
    Land with Highway Frontage
    $1,900,000
    102.70 Acres

    Land with Highway Frontage

    Commercial land with highway and state road frontage.

    125 Armstrong Road, Seneca, SC 29678
    View details
    Seneca Office Space For Sale
    $599,000
    2,400 SF

    Seneca Office Space For Sale

    Office space conveniently located off Bypass 123 in Seneca, SC.

    631 By Pass 123, Seneca, SC
    View details
    Seneca Office Space For Rent
    Contact for pricing
    2,900 SF

    Seneca Office Space For Rent

    Office space in the heart of Seneca, ample parking.

    735 N Townville St, Seneca, SC
    View details
    Oconee County Land For Sale
    $619,943

    Oconee County Land For Sale

    24.7 acres of unrestricted land near Lake Keowee.

    8006 Keowee School Road, Seneca, SC 29672
    View details
    Seneca Self-Storage Facility for Sale
    $3,000,000

    Seneca Self-Storage Facility for Sale

    Self-storage facility in Seneca, SC, available for purchase.

    420 Sitton Shoals Rd, Seneca, SC 29678
    View details
    The Clemson Commercial Lot
    $175,000
    84,942 SF

    The Clemson Commercial Lot

    1.95 Acres Land, The Clemson Commercial Lot

    189 Seneca Creek Road, Seneca, SC 29678
    View details
    The Clemson Commercial Lot
    $175,000
    84,942 SF

    The Clemson Commercial Lot

    1.95 Acres Land, The Clemson Commercial Lot

    189 Seneca Creek Road, Seneca, SC 29678
    View details
    Commercial Land Near Highway 123
    $699,000
    1.80 Acres

    Commercial Land Near Highway 123

    Unrestricted 1.8-acre commercial land near major retailers and highways.

    1.8 Acres Rochester Highway, Seneca, SC 29672
    View details
    60 Acres Land 101 Friendship Road Tract B
    $1,000,000
    2,613,600 SF

    60 Acres Land 101 Friendship Road Tract B

    A convenient 60 acres to everything Clemson

    101 Friendship Road, Seneca, SC 29678
    View details
    60 Acres Land 101 Friendship Road Tract B
    $1,000,000
    2,613,600 SF

    60 Acres Land 101 Friendship Road Tract B

    A convenient 60 acres to everything Clemson

    101 Friendship Road, Seneca, SC 29678
    View details

    Seneca, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 30 commercial real estate for sale in Seneca, SC, showcased through 30 active listings on our real estate platform. These investment opportunities span a total of 6,795,796 square feet of properties for sale, with an estimated market value of $10,165,900.

    Sale prices for business properties in Seneca, SC start at $249,900, averaging $847,158, and reaching up to $1,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Commercial real estate for Sale Near Seneca, SC

    Popular Searches in Seneca, SC

    Popular Categories

    Most Searched ZIP Codes in Seneca, SC

    • 29678
    • 29672

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!