Lancaster, SC Commercial real estate for sale

Updated: May 28

Commercial Land with Highway Frontage

2383 Charlotte Highway, Lancaster, SC 29720

$2,200,000

15.55 AC lot

15.55 acres of commercial land across two parcels: 8.88 acres and 6.67 acres
463' of road frontage along Charlotte Highway/Hwy 521
G‑B zoning, identified as General Business
Stated daily traffic count of 27,500
Borders Lancaster Medical Park

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Updated: Sep 8

Commercial Land with Office Building

731 S Market Street, Lancaster, SC 29720

$140,000

1.62 AC lot

1.62‑acre commercial parcel
B3 General Business zoning
Existing office building positioned along the edge of the lot
Approximately 270 feet of frontage on S Market Street
Public water and sewer on site

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Vacant Storefront Building

401 E Gay Street, Lancaster, SC 29720

$134,999

0.12 AC lot

Existing parking and a flexible commercial building support a range of potential business uses.

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NNN Automotive Property

1878 Great Falls Hwy, Lancaster, SC 29720

$1,400,000

7,000 sqft

Net-leased automotive retail property with a corporate guarantee and more than seven years remaining on the lease.

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Commercial Land Near Proposed Intersection

Charlotte Hwy lot: 2, Lancaster, SC 29720

$2,500,000

18.00 AC lot

Eighteen-acre tract with proposed commercial rezoning and public sewer identified near Charlotte Highway.

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General Business Commercial Land

2383 Charlotte Highway, Lancaster, SC 29720

$2,200,000

15.55 AC lot

General Business-zoned land with substantial highway frontage and proximity to Lancaster Medical Park.

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Fenced Agricultural Land

1049 Culp Ferguson Road, Lancaster, SC 29720

$2,775,000

84.67 AC lot

Fenced farmland features open fields, pastures, wooded buffers, rolling terrain, and a pond.

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Two-Building Storefront Property

1313, 1317 Hwy 9 Bypass W, Lancaster, SC 29720

$499,000

2,175 sqft

Commercial property with existing retail occupancy and dry-cleaning equipment included.

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Farmland Tract with Road Frontage

6327 Witherspoon Trail, Lancaster, SC 29720

$625,000

19.32 AC lot

Zoned RN farmland tract with county water available and septic needed, plus natural water features along the property.

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Wooded Acreage with Open Areas

Bath Lane, Lancaster, SC 29720

$199,500

11.12 AC lot

11.12-acre parcel with mature trees and open areas, offering flexibility for residential, agricultural, or recreational use.

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Commercial Building with Fenced Parking

305 E Arch St Unit 36, Lancaster, SC 29720

$250,000

1,653 sqft

Commercial building with open area, offices, and parking.

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Land For Sale, Lancaster SC

10129 Lakeshore Drive, Lancaster, SC 29720

$75,000

0.47 AC lot

Commercial land available in Lancaster, South Carolina.

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Two-Building Office Property

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000

0.82 AC lot

One building is configured for medical office use, while the other includes open space and upper-level workstations.

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Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

Contact for pricing

29,151 sqft

Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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Flat Undeveloped Land Parcel

2233 Riverside Road, Lancaster, SC 29720

$360,000

7.00 AC lot

Flat, undeveloped 7-acre parcel in Lancaster, SC with no HOA restrictions, offering flexibility for a variety of uses.

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Brick Storefront Property

2836 Lynwood Drive, Lancaster, SC 29720

$149,900

0.47 AC lot

Commercial space with central air, electric heat, carpet flooring, and a bathroom.

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Downtown Mixed-Use Building for Renovation

229 S. Main Street, Lancaster, SC 29720

Contact for pricing

15,266 sqft

Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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Corner Commercial Land

S Main Street, Lancaster, SC 29720

$272,500

1.81 AC lot

Corner-site commercial land with public water and sewer at a four-lane intersection.

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Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

Contact for pricing

22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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Corner Commercial Land

Hwy 200 Bypass, Lancaster, SC 29720

$392,000

3.14 AC lot

Three adjoining lots offer commercial land with public water and sewer at a multi-lane intersection.

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Office Building

312 N Main Street N, Lancaster, SC 29720

Contact for pricing

2,706 sqft

Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

Contact for pricing

29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Waterfront Wedding Event Venue Property

4223 Cedar Creek Rd, Lancaster, SC 29720

Contact for pricing

5,000 sqft

Boutique event venue on a bluff overlooking the Catawba River with purpose-built indoor space and outdoor gathering areas.

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Warehouse with Drive-Through Bays

1384 Camp Creek Road, Lancaster, SC 29720

Contact for pricing

8 sqft 8.67 AC lot

Industrial facility with loading infrastructure, vehicle parking, and LI zoning.

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Lancaster, SC Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Lancaster, SC, showcased through 47 active listings on our real estate platform. These investment opportunities span a total of 119,782 square feet of properties for sale, with an estimated market value of $25,102,153.

Sale prices for business properties in Lancaster, SC start at $65,000, averaging $784,442, and reaching up to $3,550,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Lancaster, SC CRE market trends — vacancy, lease rates and price per SF, updated monthly

Neighborhood	Average Price
Lancaster - 29720	$696.4K
Fort Mill - 29707	$2M

Neighborhood

Average Price

Lancaster - 29720

$696.4K

Fort Mill - 29707

$2M