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    Lancaster, SC Commercial Real Estate for Sale

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    Fort Lawn, SC Heath Springs, SC Waxhaw, NC
    52 results
    Prime Development Land Lancaster, SC
    $2,200,000
    15.55 Acres

    Prime Development Land Lancaster, SC

    2383 Charlotte Highway, Lancaster, SC 29720

    Development opportunity on a growing corridor near residential communities.

    • Prime development opportunity on Charlotte Hwy/Hwy 521, Lancaster County's fastest‑growing corridor.
    • Zoned General Business with a high daily traffic count of 27,500.
    • Located beside Lancaster Medical Park and surrounded by new residential communities.
    • Proximity to major upcoming developments: Lennar Homes' Roselyn Community (1.3 miles) and DR Horton's New Community (0.5 miles).
    • Total of 15.55 acres (8.88 Acres & 6.67 Acres) with 463 feet of road frontage.
    Updated: May 28
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    Versatile Land on Charlotte Highway
    $1,500,000
    5.61 Acres

    Versatile Land on Charlotte Highway

    Charlotte Highway, Lancaster, SC 29707

    5.61-acre wooded property with residential and commercial potential.

    • 5.61‑acre wooded property with residential and unimproved commercial potential.
    • Prime location on the corner of 521 and Henry Harris, with road frontage on a 4‑lane state highway, offering excellent visibility and convenient access.
    • Future land use map indicates potential for Commercial Zoning (as of 9/26/25) with Design and Environmental guidelines.
    • County Water available on 521 (tap fee required).
    • Subdivision possible (up to 3 lots due to moratorium).
    Updated: Nov 8, 2025
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    Prime Land on Highway 521
    $2,500,000
    3.96 Acres

    Prime Land on Highway 521

    3.96 acres ideal for commercial or residential development.

    6993 Charlotte Highway, Lancaster, SC 29707
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    Lancaster Commercial Building For Sale
    $139,999
    0.12 Acres

    Lancaster Commercial Building For Sale

    Commercial building in growing area with business or investment potential.

    401 E Gay Street, Lancaster, SC 29720
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    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    1201 Colonial Commons Court, Lancaster, SC 29720
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    Lancaster Land with Highway Frontage
    $1,600,000
    25.00 Acres

    Lancaster Land with Highway Frontage

    25 acres of land ideal for development or investment.

    3080 Charlotte Highway, Lancaster, SC 29720
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    Prime Commercial Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Commercial Land on Charlotte Highway

    15.55 acres on Charlotte Hwy near new developments.

    2383 Charlotte Highway, Lancaster, SC 29720
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    19.32 Acres in Indian Land
    $625,000
    19.32 Acres

    19.32 Acres in Indian Land

    Land with natural features ideal for country living.

    6327 Witherspoon Trail, Lancaster, SC 29720
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    Lancaster County Acreage with Development Potential
    $2,775,000
    84.67 Acres

    Lancaster County Acreage with Development Potential

    84.67 acres in Lancaster County ideal for various uses.

    1049 Culp Ferguson Road, Lancaster, SC 29720
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    Versatile Commercial Building in Lancaster
    $349,000

    Versatile Commercial Building in Lancaster

    Two-story commercial building with offices in downtown Lancaster, SC.

    302 N White St, Lancaster, SC 29720
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    Commercial Land in Lancaster, SC
    $75,000
    0.28 Acres

    Commercial Land in Lancaster, SC

    Prime commercial location with high visibility and easy access.

    E Arch Street, Lancaster, SC 29720
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    Lancaster Commercial Land For Sale
    $2,500,000
    18.00 Acres

    Lancaster Commercial Land For Sale

    Commercial land with development potential in Lancaster, South Carolina.

    Charlotte Hwy lot: 2, Lancaster, SC 29720
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    Medical Office Buildings Near MUSC
    $975,000

    Medical Office Buildings Near MUSC

    Two professional buildings suitable for medical or office use.

    1201 Colonial Commons Ct, Lancaster, SC 29720
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    Mixed-Use Investment Opportunity
    $1,150,000
    20,606 SF

    Mixed-Use Investment Opportunity

    Multi-tenant property with retail, office, industrial, and storage units.

    979-987 University Dr, Lancaster, SC
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    Lancaster County Timberland Tract
    $1,332,500
    533.00 Acres

    Lancaster County Timberland Tract

    533-acre recreational timberland tract in Lancaster County, South Carolina.

    Duckwood Rd., Lancaster, SC 29720
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    Turnkey Event Venue on 10.5 Acres
    $2,500,000
    6,058 SF

    Turnkey Event Venue on 10.5 Acres

    Established event venue in Lancaster, South Carolina, ready for operation.

    6815 Shiloh Unity Rd, Lancaster, SC 29720
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    Retail Buildings For Sale
    $550,000
    2,175 SF

    Retail Buildings For Sale

    Two commercial buildings for sale in a growing area.

    1317 Hwy 9 ByPass W, Lancaster, SC 29720
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    Wooded Acreage in Lancaster, SC
    $210,000
    11.12 Acres

    Wooded Acreage in Lancaster, SC

    11.12 acres of wooded land suitable for various uses.

    Bath Lane, Lancaster, SC 29720
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    Lancaster Farmland with Barn
    $799,900
    39.80 Acres

    Lancaster Farmland with Barn

    39.8 acres of rolling farmland with barn and ponds.

    992 S Potter Road, Lancaster, SC 29720
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    Land For Sale, Lancaster SC
    $75,000
    0.47 Acres

    Land For Sale, Lancaster SC

    Commercial land available in Lancaster, South Carolina.

    10129 Lakeshore Drive, Lancaster, SC 29720
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    Thriving Child Development Center
    $3,200,000
    9,398 SF

    Thriving Child Development Center

    Child development center with two buildings and outdoor playground.

    1699 N Rocky River Road, Lancaster, SC 29720
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    Lancaster County Land For Sale
    $2,412,750
    64.34 Acres

    Lancaster County Land For Sale

    Approximately 64 acres available in Lancaster County Airport Industrial Park.

    Chester Hwy, Lancaster, SC
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    Lancaster Convenience Store Opportunity
    $350,000

    Lancaster Convenience Store Opportunity

    Turnkey convenience store for sale with building, land, and inventory.

    715 S Market Street, Lancaster, SC 29720
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    Commercial Building with Fenced Parking
    $250,000
    1,653 SF

    Commercial Building with Fenced Parking

    Commercial building with open area, offices, and parking.

    305 E Arch Street #36, Lancaster, SC 29720
    View details

    Lancaster, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Lancaster, SC, showcased through 52 active listings on our real estate platform. These investment opportunities span a total of 51,438 square feet of properties for sale, with an estimated market value of $8,973,900.

    Sale prices for business properties in Lancaster, SC start at $149,900, averaging $1,121,737, and reaching up to $3,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Property Size Breakdown

    The majority of commercial real estate listings in Lancaster fall within the 5,000 to 10,000 square foot range.

    Demographics Overview

    Population 52K
    Population Growth (5Y) +8.0%
    Median Household Income $59,039
    College Educated 9.5%

    High-Yield Neighborhoods for Investment

    Identify Lancaster submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    Lancaster $844.1K
    Fort Mill $2M

    Taxes & Financing

    Average Loan-to-Value 65.0%

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    Most Searched ZIP Codes in Lancaster, SC

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