Lancaster, SC Commercial Real Estate for Sale

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Updated: May 28

Prime Development Land Lancaster, SC

2383 Charlotte Highway, Lancaster, SC 29720

$2,200,000

15.55 AC lot

Prime development opportunity on Charlotte Hwy/Hwy 521, Lancaster County's fastest‑growing corridor.
Zoned General Business with a high daily traffic count of 27,500.
Located beside Lancaster Medical Park and surrounded by new residential communities.
Proximity to major upcoming developments: Lennar Homes' Roselyn Community (1.3 miles) and DR Horton's New Community (0.5 miles).
Total of 15.55 acres (8.88 Acres & 6.67 Acres) with 463 feet of road frontage.

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Updated: Jun 12

Adjacent Single-Family Rental Portfolio

209 Rickenbacker Street, Lancaster, SC 29720

$985,000

0.88 AC lot

Eight‑home single‑family rental portfolio in Lancaster, SC, with all properties adjacent on the same street
Each home is a 2‑bedroom, 1‑bath single‑family residence
Portfolio is 100% occupied and generates approximately $7,000 in gross monthly rental income
20' x 20' storage warehouse located behind 237 Rickenbacker Street, with most contents conveying at closing
Vacant lot situated between the corner and 237 Rickenbacker Street, included with the offering

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Lancaster Commercial Building For Sale

401 E Gay Street, Lancaster, SC 29720

$139,999

0.12 AC lot

Commercial building in growing area with business or investment potential.

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Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

$575,000

29,151 sqft

Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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Lancaster Land with Highway Frontage

3080 Charlotte Highway, Lancaster, SC 29720

$1,600,000

25.00 AC lot

25 acres of land ideal for development or investment.

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Lancaster Commercial Land For Sale

Charlotte Hwy lot: 2, Lancaster, SC 29720

$2,500,000

18.00 AC lot

Commercial land with development potential in Lancaster, South Carolina.

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19.32 Acres in Indian Land

6327 Witherspoon Trail, Lancaster, SC 29720

$625,000

19.32 AC lot

Land with natural features ideal for country living.

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Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

$760,000

22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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Lancaster County Acreage with Development Potential

1049 Culp Ferguson Road, Lancaster, SC 29720

$2,775,000

84.67 AC lot

84.67 acres in Lancaster County ideal for various uses.

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General Business Development Land

2383 Charlotte Highway, Lancaster, SC 29720

$2,200,000

15.55 AC lot

Two-parcel tract with 463 feet of road frontage on Charlotte Highway, positioned beside Lancaster Medical Park in a growing residential corridor.

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1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

$575,000

29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Lancaster Farmland with Barn

992 S Potter Road, Lancaster, SC 29720

$799,900

39.80 AC lot

39.8 acres of rolling farmland with barn and ponds.

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Wooded Acreage in Lancaster, SC

Bath Lane, Lancaster, SC 29720

$210,000

11.12 AC lot

11.12 acres of wooded land suitable for various uses.

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Waterfront Wedding Event Venue Property

4223 Cedar Creek Rd, Lancaster, SC 29720

$2,400,000

5,000 sqft

Boutique event venue on a bluff overlooking the Catawba River with purpose-built indoor space and outdoor gathering areas.

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Land For Sale, Lancaster SC

10129 Lakeshore Drive, Lancaster, SC 29720

$75,000

0.47 AC lot

Commercial land available in Lancaster, South Carolina.

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Two-Building Professional Office Property

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000

0.82 AC lot

Two professional buildings offer medical-office rooming and upper-level work areas on a single property.

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Downtown Mixed-Use Building for Renovation

229 S. Main Street, Lancaster, SC 29720

$275,000

15,266 sqft

Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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Commercial Land in Lancaster, SC

2836 Lynwood Drive, Lancaster, SC 29720

$149,900

0.47 AC lot

Commercial land suitable for various business ventures.

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Mixed-Use Investment Opportunity

979-987 University Dr, Lancaster, SC

$1,150,000

20,606 sqft 2.15 AC lot

Multi-tenant property with retail, office, industrial, and storage units.

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Commercial Land on Corner Lot

S Main Street, Lancaster, SC 29720

$272,500

1.81 AC lot

Corner lot commercial land with road frontage and utilities.

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Retail Buildings For Sale

1317 Hwy 9 ByPass W, Lancaster, SC 29720

$550,000

2,175 sqft

Two commercial buildings for sale in a growing area.

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Commercial Land on Highway 200

Hwy 200 Bypass, Lancaster, SC 29720

$392,000

3.14 AC lot

3.14 acre commercial land with road frontage.

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Thriving Child Development Center

1699 N Rocky River Road, Lancaster, SC 29720

$3,200,000

9,398 sqft

Child development center with two buildings and outdoor playground.

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Commercial Building with Fenced Parking

305 E Arch Street #36, Lancaster, SC 29720

$250,000

1,653 sqft

Commercial building with open area, offices, and parking.

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Lancaster, SC Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Lancaster, SC, showcased through 42 active listings on our real estate platform. These investment opportunities span a total of 153,164 square feet of properties for sale, with an estimated market value of $14,269,000.

Sale prices for business properties in Lancaster, SC start at $250,000, averaging $1,297,181, and reaching up to $4,235,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 52K

Population Growth (5Y) +8.0%

Median Household Income $59,039

College Educated 9.5%

High-Yield Neighborhoods for Investment

Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
Lancaster	$808.4K
Fort Mill	$2M

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Lancaster County

New Delisted

Property Size Breakdown

The majority of commercial real estate listings in Lancaster fall within the 5,000 to 10,000 square foot range.

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