Lancaster, SC Commercial Real Estate for Sale

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Fort Lawn, SC Waxhaw, NC Heath Springs, SC Catawba, SC Richburg, SC Edgemoor, SC Great Falls, SC Van Wyck, SC

59 properties

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Updated: May 15

Vacant Storefront Building

401 E Gay Street, Lancaster, SC 29720

$139,999

0.12 AC lot

Storefront building constructed in 1960
Vacant for approximately one year
0.12‑acre lot
Parking lot included with the property
Parking area located beside the barbershop

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Updated: Jan 5

Commercial Land Near Planned Intersection

Charlotte Hwy lot: 2, Lancaster, SC 29720

$2,500,000

18.00 AC lot

18‑acre land tract with approximately 10 usable acres outside the flood plain
Proposed rezoning would place the property in a Commercial zone, subject to Lancaster County approval
Public sewer listed for the property
Buyer to verify the actual location of water and sewer near Highway 521
Proposed Henry Harris extension to Van Wyck could create a traffic‑light intersection

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General Business Development Land

2383 Charlotte Highway, Lancaster, SC 29720

$2,200,000

15.55 AC lot

Two-parcel tract with 463 feet of road frontage on Charlotte Highway, positioned beside Lancaster Medical Park in a growing residential corridor.

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NNN Automotive Property

1878 Great Falls Hwy, Lancaster, SC 29720

$1,400,000

7,000 sqft

Net-leased automotive retail property with a corporate guarantee and more than seven years remaining on the lease.

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Fenced Agricultural Land

1049 Culp Ferguson Road, Lancaster, SC 29720

$2,775,000

84.67 AC lot

Fenced farmland features open fields, pastures, wooded buffers, rolling terrain, and a pond.

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Farmland with Barn and Ponds

992 S Potter Road, Lancaster, SC 29720

$799,900

39.80 AC lot

LDR-zoned agricultural acreage with a barn, elevator, ponds, and county water availability.

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Farmland Tract with Road Frontage

6327 Witherspoon Trail, Lancaster, SC 29720

$625,000

19.32 AC lot

Zoned RN farmland tract with county water available and septic needed, plus natural water features along the property.

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Commercial Building with Fenced Parking

305 E Arch Street #36, Lancaster, SC 29720

$250,000

1,653 sqft

Commercial building with open area, offices, and parking.

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Wooded Acreage with Open Areas

Bath Lane, Lancaster, SC 29720

$199,500

11.12 AC lot

11.12-acre parcel with mature trees and open areas, offering flexibility for residential, agricultural, or recreational use.

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Two-Building Medical Office Property

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000

0.82 AC lot

Professional office compound with medical layouts, reception areas, waiting rooms, and separate work areas across two buildings.

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Historic Mixed-Use Retail/Office Buildings

209-227 S. Main Street, Lancaster, SC 29720

Contact for pricing

29,151 sqft

Vacant 1930s buildings offer retail or office space and renovation opportunity in downtown Lancaster, South Carolina.

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Land For Sale, Lancaster SC

10129 Lakeshore Drive, Lancaster, SC 29720

$75,000

0.47 AC lot

Commercial land available in Lancaster, South Carolina.

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Flat Undeveloped Land Parcel

2233 Riverside Road, Lancaster, SC 29720

$360,000

7.00 AC lot

Flat, undeveloped 7-acre parcel in Lancaster, SC with no HOA restrictions, offering flexibility for a variety of uses.

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Downtown Mixed-Use Building for Renovation

229 S. Main Street, Lancaster, SC 29720

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15,266 sqft

Vacant 1930s mixed-use property in downtown Lancaster, built for retail or office re-activation with renovation underway.

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Land, Lancaster, SC

329 Pineview Court Lane, Lancaster, SC 29720

$115,000

3.05 AC lot

Agricultural land / Farmland · 3.05 Acres

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Brick Storefront Property

2836 Lynwood Drive, Lancaster, SC 29720

$149,900

0.47 AC lot

Commercial space with central air, electric heat, carpet flooring, and a bathroom.

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Downtown Mixed-Use Redevelopment Property

210 S. White Street, Lancaster, SC 29720

Contact for pricing

22,251 sqft

Vacant 1930s retail/office buildings in downtown Lancaster offer a renovation-ready canvas for mixed-use redevelopment.

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Corner Commercial Land

S Main Street, Lancaster, SC 29720

$272,500

1.81 AC lot

Corner-site commercial land with public water and sewer at a four-lane intersection.

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1930s Retail/Office Building Portfolio

116 Arch Street, Lancaster, SC 29720

Contact for pricing

29,444 sqft

Vacant, renovation-needed buildings offering flexible retail or office space in downtown Lancaster with convenient highway access.

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Corner Commercial Land

Hwy 200 Bypass, Lancaster, SC 29720

$392,000

3.14 AC lot

Three adjoining lots offer commercial land with public water and sewer at a multi-lane intersection.

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Office Building

312 N Main Street N, Lancaster, SC 29720

Contact for pricing

2,706 sqft

Office building with some furnishings staying, and utility split where tenant pays electricity and natural gas.

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Climate Controlled Warehouse with Docks

1551 Hwy 9 Byp, Lancaster, SC 29720

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349,000 sqft

100% climate controlled warehouse with multiple dock doors, in-place racking, and overhead production clearances.

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Waterfront Wedding Event Venue Property

4223 Cedar Creek Rd, Lancaster, SC 29720

Contact for pricing

5,000 sqft

Boutique event venue on a bluff overlooking the Catawba River with purpose-built indoor space and outdoor gathering areas.

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Warehouse with Drive-Through Bays

1384 Camp Creek Road, Lancaster, SC 29720

Contact for pricing

8 sqft 8.67 AC lot

Industrial facility with loading infrastructure, vehicle parking, and LI zoning.

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Lancaster, SC Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Lancaster, SC, showcased through 59 active listings on our real estate platform. These investment opportunities span a total of 480,947 square feet of properties for sale, with an estimated market value of $25,028,053.

Sale prices for business properties in Lancaster, SC start at $75,000, averaging $782,126, and reaching up to $3,550,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 52K

Population Growth (5Y) +8.0%

Median Household Income $59,039

College Educated 9.5%

High-Yield Neighborhoods for Investment

Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
Lancaster - 29720	$702.2K
Fort Mill - 29707	$2M

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Lancaster County

New Delisted

Property Size Breakdown

The majority of commercial real estate listings in Lancaster fall within the 5,000 to 10,000 square foot range.

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