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    Anderson County, SC Commercial Real Estate for Sale

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    289 properties
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    Automotive Shop with Road Frontage
    Updated: May 18
    Automotive Shop with Road Frontage

    224 S Main St, Belton, SC 29627

    $625,000
    1,504 sqft 0.76 AC lot
    1,504‑square‑foot building on 0.76 acres
    Currently operating as a tire and brake shop
    Over 2900 feet of road frontage
    Located at 224 S Main St, Belton, SC 29627
    Anderson County commercial property
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    Historic Mixed-Use Building
    Updated: May 12
    Historic Mixed-Use Building

    222 City Square, Belton, SC 29627

    $299,000
    8,000 sqft 0.11 AC lot
    Approximately 8,000 square feet on a 0.11‑acre parcel
    Historic building at 222 City Square in downtown Belton
    Upper level offers residential adaptation potential
    Surrounded by dining, retail, and civic spaces
    On‑site parking for patrons and staff
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    Downtown Auto Shop
    Downtown Auto Shop

    705 Anderson, Belton, SC 29627

    $300,000
    2,356 sqft 0.35 AC lot

    Existing facility supports automotive, boat, and RV detailing with ceramic coating operations.

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    Flex Building With Drive-In Doors
    Flex Building With Drive-In Doors

    1007 South Murray Avenue, Anderson, SC 29624

    $525,000
    9,780 sqft 0.85 AC lot

    General Commercial zoning combines renovated office/showroom space with warehouse functionality.

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    Former Restaurant Property
    Former Restaurant Property

    6130 Belton Hwy, Belton, SC 29627

    $325,000
    2,000 sqft 0.71 AC lot

    Commercial property in Belton with a prior restaurant use and a convenient highway address.

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    Brick Live-Work Property
    Brick Live-Work Property

    510 E Calhoun Street, Anderson, SC 29621

    $350,000
    0.26 AC lot

    Residential Office zoning supports a combination of living space and professional office use.

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    Mixed-Use Property with Event Center
    Mixed-Use Property with Event Center

    202-208 W Franklin Street, Anderson, SC 29624

    $499,900
    0.81 AC lot

    A recently renovated commercial facility combines convenience retail, food service, a bar, and event space.

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    6-Bay Auto Shop
    6-Bay Auto Shop

    1706 Pearman Dairy Road, Anderson, SC 29625

    $675,000
    5,943 sqft

    Several work buildings feature automotive equipment and shop systems for service, collision, fabrication, light industrial, or contractor use.

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    Commercial Land with Road Frontage
    Commercial Land with Road Frontage

    6131 Belton Highway, Belton, SC 29627

    $500,000
    4.00 AC lot

    Four-acre commercial parcel with access from Belton Highway and frontage along three roads.

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    Retail Strip Mall Building
    Retail Strip Mall Building

    110 Miracle Mile Drive, Anderson, SC 29621

    $3,900,000
    2.76 AC lot

    Block construction, metal roofing, and mixed tile, concrete, and laminate flooring define the existing improvements.

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    Frontage Flex Space
    Frontage Flex Space

    3911 Hwy 24, Anderson, SC 29626

    $840,000
    8,411 sqft 2.56 AC lot

    Two-building light industrial property with on-site parking and access along the Hwy 24 corridor.

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    Commercial Land at Interstate Interchange
    Commercial Land at Interstate Interchange

    105 Destination Boulevard, Anderson, SC 29621

    $949,000
    1.80 AC lot

    Commercial land positioned along I-85 near a major US 76-28 interchange, with public water available.

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    Brick Office Building with Eight Offices
    Brick Office Building with Eight Offices

    203 N Hamilton Street, Williamston, SC 29697

    $279,900
    0.47 AC lot

    Corner-lot office property with multiple entrances, a kitchenette, and public water service.

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    Medical Office Building For Sale
    Medical Office Building For Sale

    102 Buford Avenue, Anderson, SC 29621

    $1,050,000
    10,405 sqft

    Multi-tenant medical office building near AnMed campuses with development potential.

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    Restaurant with Expansion Land
    Restaurant with Expansion Land

    103 Jonathan Street, Pendleton, SC 29670

    $1,300,000
    1.22 AC lot

    An operating restaurant and adjoining commercial parcel combine in a two-parcel commercial offering.

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    Commercial Land
    Commercial Land

    158 Hurricane Road, Anderson, SC 29621

    $714,000
    4.71 AC lot

    The tract may accommodate storage, warehouse, industrial, or residential use.

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    Prime Anderson Commercial Corner Property
    Prime Anderson Commercial Corner Property

    110 E Greenville St, Anderson, SC 29621

    $2,300,000
    14,000 sqft 1.21 AC lot

    Multi-tenant property on 1.21 acres in Anderson's commercial hub.

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    Buildable Commercial Land
    Buildable Commercial Land

    120 Perpetual Square, Anderson, SC 29621

    $770,000
    1.50 AC lot

    Buildable commercial land along Highway 81 North in Anderson, suitable for a medical office or other enterprise.

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    Historic Mixed-Use Retail Building
    Historic Mixed-Use Retail Building

    222 City Square, Belton, SC 29627

    $299,000
    8,000 sqft

    Historic downtown building offering multi-use space and residential potential, with generous parking for patrons and staff.

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    9.8 Acres Commercial Land Anderson
    9.8 Acres Commercial Land Anderson

    Pearman Dairy Road, Anderson, SC 29625

    $649,000
    9.80 AC lot

    9.8 acres of commercial land in high-visibility Anderson location.

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    Belton Commercial Opportunity For Sale
    Belton Commercial Opportunity For Sale

    224 S Main St, Belton, SC 29627

    $625,000
    1,504 sqft

    Versatile commercial property in high-traffic Belton location.

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    Drive-Through Restaurant Property
    Drive-Through Restaurant Property

    1107 McKelvey Road, Pelzer, SC 29669

    $350,000
    0.40 AC lot

    Includes a drive-through layout with rear picnic and outdoor areas for customer use.

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    Downtown Flex Space
    Downtown Flex Space

    215 W Church Street, Anderson, SC 29624

    $430,000
    6,400 sqft 0.32 AC lot

    Shell-condition commercial property with three-phase power, concrete first floors, and a configurable multi-level layout.

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    Single-Story Industrial Building
    Single-Story Industrial Building

    840 Bleckley Street, Anderson, SC 29625

    $165,000
    0.37 AC lot

    The property carries NC zoning, and garage use is no longer permitted.

    View details
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    Anderson County, SC Commercial Real Estate Market Trends and Statistics

    Explore 289 commercial real estate for sale in Anderson County, SC, showcased through 289 active listings on our real estate platform. These investment opportunities span a total of 8,403,856 square feet of properties for sale, with an estimated market value of $142,886,918.

    Sale prices for business properties in Anderson County, SC start at $32,000, averaging $585,602, and reaching up to $4,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Anderson County Real Estate Agencies

    Realmo connects you with licensed Anderson County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Keller Williams Western Upstate
    4107 Liberty Highway Anderson, SC 29621
    Phone: (864) 225-8006
    mc842.yourkwoffice.com
    CANN LAND & TIMBER, LLC
    105 ANDERSON AVE Anderson, SC
    Phone: (864) 965-9023
    RE/MAX EXECUTIVE
    100 A MIRACLE MILE DRIVE Anderson, SC
    Phone: (864) 622-3636
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