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    Florence County, SC Commercial Real Estate for Lease

    33 results
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    Versatile Commercial Space in Florence
    $5,000 / Mo
    11,390 SF

    Versatile Commercial Space in Florence

    374 Darlington St, Florence, SC 29501

    Commercial property with bay doors, ideal for automotive or warehouse.

    • Prime Downtown Florence, SC location
    • Multiple bay doors for easy access and operations
    • Versatile space suitable for automotive, warehouse, or service‑related businesses
    • Abundant open space for vehicles, equipment, or flexible use
    • Dedicated office space for administrative functions
    Updated: Oct 6, 2025
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    Restaurant Space Near I-95
    $7,680 / Mo
    4,190 SF

    Restaurant Space Near I-95

    3751 W Palmetto St, Florence, SC 29501

    Restaurant space for lease with high visibility and traffic.

    • High traffic location with 36,300 vehicles daily on I‑95 and 17,800 vehicles daily on US‑76.
    • Excellent visibility and accessibility with copious road frontage, two driveway entrances, and ample parking.
    • Located off I‑95 Exit 157.
    • Surrounded by established national brands (McDonald’s, Waffle House, etc.).
    • 4,190 SF restaurant space available for lease.
    Updated: Sep 2, 2025
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    Restaurant Space Near I-95
    $7,680 / Mo
    4,190 SF

    Restaurant Space Near I-95

    Restaurant space for lease with high visibility and traffic.

    3751 W Palmetto St, Florence, SC 29501
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    Office Space Near Timrod Park
    $700 / Mo
    150 SF

    Office Space Near Timrod Park

    Flexible office spaces in historic building near Timrod Park.

    720 S Coit St, Florence, SC 29501
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    Claussen Retail Center Space Available
    $12 SF/Yr
    47,905 SF

    Claussen Retail Center Space Available

    Grocery-anchored retail space in Florence, SC.

    2332 Pamplico Hwy, Florence, SC 29505
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    Prime Florence Office Space
    $22 SF/Yr
    48,770 SF

    Prime Florence Office Space

    Executive Suites, Full-Service, 48,770 SF

    1831 Evans St, Florence, SC 29501
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    Florence County Executive Office Space
    Contact for pricing
    16,800 SF

    Florence County Executive Office Space

    Modern Flex Space, 10,500 SF Available

    2315 Prosperity Way, Florence, SC 29501
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    Florence Office Space For Lease
    $10 SF/Yr
    2,300 SF

    Florence Office Space For Lease

    2300 sq ft Flex Space, I-95 Access

    1092 Church St, Florence, SC 29506
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    Downtown Florence Office Suite A
    $226 SF/Yr
    1,400 SF

    Downtown Florence Office Suite A

    1400 sq ft Executive Office Space for Lease

    620 Evans St, Florence, SC 29501
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    Habersham Square Flex Space Available
    Contact for pricing
    2,450 SF

    Habersham Square Flex Space Available

    Modern Flex Space, Prime Location, 2450 sqft

    1838 Habersham Sq, Florence, SC 29501
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    Downtown Florence Flex Space
    $7 SF/Yr
    9,880 SF

    Downtown Florence Flex Space

    9,880 SF Flex Warehouse For Lease

    312 Railroad Ave, Florence, SC 29506
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    Florence Crossing Retail Center
    $22 SF/Yr
    9,775 SF

    Florence Crossing Retail Center

    Prime Retail Space Available in Florence, SC

    100-110 Woody Jones Blvd, Florence, SC 29501
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    Irby Street Retail Opportunity
    Contact for pricing
    86,324 SF

    Irby Street Retail Opportunity

    High-traffic retail space available

    1611 Irby St, Florence, SC 29505
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    Logan Plaza: Prime Office Space
    Contact for pricing
    7,900 SF

    Logan Plaza: Prime Office Space

    Florence, SC Office Suites Available

    1800 2Nd Loop Rd, Florence, SC 29501
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    High Hill Commerce Park: Florence, SC
    Contact for pricing
    150,000 SF

    High Hill Commerce Park: Florence, SC

    New Flex/Warehouse Space Available

    0 Enterprise Dr, Florence, SC 29501
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    Southside Commons Retail Space
    Contact for pricing
    37,488 SF

    Southside Commons Retail Space

    Florence, SC Retail Center - 1 Space Available

    2014 Irby St, Florence, SC 29505
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    Florence Office Space: 7,145 SF
    $22 SF/Yr
    74,186 SF

    Florence Office Space: 7,145 SF

    Prime Florence Office: Modern, Customizable Space

    2701 Alex Lee Blvd, Florence, SC 29506
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    Florence Industrial Warehouse - 300,000 SF Available
    $4 SF/Yr
    400,000 SF

    Florence Industrial Warehouse - 300,000 SF Available

    Large Industrial Space, Florence, SC

    901 Douglas St, Florence, SC 29501
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    Downtown Florence Mixed-Use Gem
    $25 SF/Yr
    7,748 SF

    Downtown Florence Mixed-Use Gem

    Historic District, prime location, flexible space.

    127 Evans St, Florence, SC 29501
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    Florence Mall Retail Space
    Contact for pricing
    329,345 SF

    Florence Mall Retail Space

    Prime Florence, SC retail center

    1945 Palmetto St, Florence, SC 29501
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    Broughton Blvd Warehouse Space
    Contact for pricing
    11,250 SF

    Broughton Blvd Warehouse Space

    ±11,250 SF Warehouse, Florence, SC

    0 Broughton Blvd, Florence, SC 29501
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    West End District Warehouse
    $90 SF/Yr
    36,360 SF

    West End District Warehouse

    36,360 SF Warehouse, Prime Location

    2295 Hoffmeyer Rd, Florence, SC 29501
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    Prime Florence Office Space
    $26 SF/Yr
    3,600 SF

    Prime Florence Office Space

    Class A Office, 1,800 SF Available

    609 2Nd Loop Rd, Florence, SC 29505
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    620 Evans St
    $216 SF/Yr
    3,000 SF

    620 Evans St

    Office Properties & Spaces

    620 Evans St, Florence, SC 29501
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    Florence County, SC Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Florence County, SC with 85 listings featured on our commercial real estate exchange. The current inventory includes 38,921,687,640 square feet of properties with an estimated lease value of $1,033 /Mo.

    Estimated lease rates for Commercial Real Estate in Florence County, SC begin at $2 SF/Yr, with an average of $43 SF/Yr and extend to $226 SF/Yr.

    In Florence County, SC, current lease rates show:

    • Office Properties & Spaces positioned at $50
    • Retail properties measuring $23
    • Industrial properties assessed at $23
    • Office space calculated at $60
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    Browse Commercial real estate for Lease Near Florence, SC

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