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Florence, SC Office Units for Lease

13 results
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Versatile Commercial Space in Florence
$5,000 /Mo
11,390 SF

Versatile Commercial Space in Florence

374 Darlington St., Florence, SC 29501

Commercial property with bay doors, ideal for automotive or warehouse.

  • Prime Downtown Florence, SC location
  • Multiple bay doors for easy access and operations
  • Versatile space suitable for automotive, warehouse, or service‑related businesses
  • Abundant open space for vehicles, equipment, or flexible use
  • Dedicated office space for administrative functions
Updated: Oct 11, 2025
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Downtown Florence Open Concept Office
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Downtown Florence Open Concept Office

620 W Evans St, Florence, SC 29501

Open concept office space with exceptional visibility in Downtown Florence.

  • Exceptional visibility entering Downtown Florence.
  • Spacious, customizable open floor plan.
  • Large conference room for meetings and presentations.
  • Private parking at the rear of the building.
  • Dedicated restroom.
Updated: Nov 1, 2024
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Office Space Across From Park
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Office Space Across From Park

Flexible office spaces for rent in historic building.

720 S Coit St., Florence, SC 29501
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Downtown Florence Mixed-Use Space
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1,800 SF

Downtown Florence Mixed-Use Space

Prime mixed-use space in Downtown Florence Historic District.

127 W Evans St, Florence, SC 29501
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Office/Storage Space For Lease
$10 SF/Yr
2,300 SF

Office/Storage Space For Lease

Office or storage space with access to I-95 and I-20.

1092 S Church St, Florence, SC 29506
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New Office Space Available
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3,600 SF

New Office Space Available

Shell space in a new building, build-out to suit.

609 2nd Loop Rd, Florence, SC 29505
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Modern Office Space For Rent
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7,145 SF

Modern Office Space For Rent

7,145 SF customizable office space in Florence, SC.

2701 Alex Lee Blvd, Florence, SC 29506
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Florence Commercial Space For Rent
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Florence Commercial Space For Rent

Commercial space suitable for office, professional, or retail use.

2843 W Palmetto Street Suite C, Florence, SC 29501
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Established Commercial Complex on Second Loop
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2,000 SF

Established Commercial Complex on Second Loop

Multi-tenant commercial complex with high visibility and convenient access.

1800 2nd Loop Rd, Florence, SC 29501
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New Metal Building Near Highways
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New Metal Building Near Highways

Newly constructed flex/industrial/office space near major highways.

2315 Prosperity Way, Florence, SC 29501
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Downtown Florence Flex Office Warehouse
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9,880 SF

Downtown Florence Flex Office Warehouse

Flex office warehouse space for lease in downtown Florence.

312 Railroad Ave, Florence, SC 29506
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Modern Flex Space For Lease
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2,450 SF

Modern Flex Space For Lease

Flex space with office and warehouse components available for lease.

1838 Habersham Square, Florence, SC 29501
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Prestigious Office Suites in Florence
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4,453 SF

Prestigious Office Suites in Florence

Corporate office suites available for lease in Florence, SC.

1831 W Evans St, Florence, SC 29501
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Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 13 Active listings in Florence, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Explore Office Units for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Warehouse and Office Space Available
$3,325 /Mo
6,042 SF

Warehouse and Office Space Available

6042 sq ft warehouse & office space for lease.

805 N Wise Drive, Sumter, SC 29153
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Office Space in Sumter, SC
$325 /Mo
298 SF

Office Space in Sumter, SC

Single office unit available for lease in Sumter, SC.

698 Bultman Drive unit: O, Sumter, SC 29150
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Office Space in Marion, SC
$1,000 /Mo
2,000 SF

Office Space in Marion, SC

Office space featuring a reception area, offices, and conference room.

1450 E Northside Avenue, Marion, SC 29571
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Industrial Warehouse with Office Space
Contact for pricing
3,600 SF

Industrial Warehouse with Office Space

Marion County warehouse with office, ideal for storage or manufacturing.

Carol White Ct, Marion, SC 29571
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Explore Similar Spaces for Sale in Florence, SC

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Industrial Buildings with Power & Access
$199,000
40,000 SF

Industrial Buildings with Power & Access

Two industrial buildings ideal for fabrication, automotive, or storage.

120 N Guerry Street, Florence, SC 29501
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Florence Commercial Building on Evans
$79,000
1,200 SF

Florence Commercial Building on Evans

Standalone building on Evans Street with redevelopment potential.

617 W Evans St, Florence, SC 29501
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Versatile Commercial Parcel Near Downtown
$499,900
67,518 SF

Versatile Commercial Parcel Near Downtown

Office, showroom, and warehouse space less than one mile from Downtown.

121 N Lawson St, Florence, SC 29501
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Standalone Industrial Building on Harrell
$189,000
40,000 SF

Standalone Industrial Building on Harrell

Industrial building suitable for fabrication, automotive, contractor, or storage.

120 N Guerry St, Florence, SC 29501
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Evans Street Commercial Redevelopment Opportunity
$79,000
1,200 SF

Evans Street Commercial Redevelopment Opportunity

Standalone building on Evans Street with redevelopment potential.

617 W Evans St, Florence, SC 29501
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Industrial Warehouse with Development Potential
$2,190,000
95,590 SF

Industrial Warehouse with Development Potential

95,590 SF industrial warehouse on 7.34 acres for sale.

906 S Church St, Florence, SC 29506
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Downtown Florence Commercial Property
Contact for pricing

Downtown Florence Commercial Property

Commercial property in downtown Florence, suitable for office or retail.

181 N Dargan, Florence, SC 29501
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Acreage on West Palmetto
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Prime Acreage on West Palmetto

Commercial land for rent near Florence Mall and Five Points.

1609 W Palmetto St, Florence, SC 29501
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Prime Land Lease Opportunity
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Prime Land Lease Opportunity

0.99 acre commercial land for lease in Florence, SC.

1815 W Palmetto St, Florence, SC 29501
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Retail Outparcel in High-Traffic Area
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Retail Outparcel in High-Traffic Area

Outparcel for ground lease or build-to-suit in Florence, SC.

500 2nd Loop Rd, Florence, SC 29505
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Laydown Yard For Lease
$0.39 SF/Yr

Laydown Yard For Lease

0.85 acre fenced laydown yard in Florence, SC.

1927 E Palmetto St, Florence, SC 29506
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Florence, SC Office Units Leasing Opportunities Market Analysis

Explore Office Units leasing options in Florence, SC with 13 listings featured on our commercial real estate exchange. The current inventory includes 496,148,400 square feet of properties with an estimated lease value of $5 SF/Yr.

Estimated lease rates for Office Units in Florence, SC begin at $5 SF/Yr, with an average of $5 SF/Yr and extend to $5 SF/Yr.
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