Add Listing
    Florence, SC
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Florence, SC Retail Properties & Spaces for Lease

    Notify Me
    List
    Map
    17 results
    Versatile Commercial Space in Florence
    $5,000/Mo
    11,390 SF

    Versatile Commercial Space in Florence

    374 Darlington St., Florence, SC 29501

    Commercial property with bay doors, ideal for automotive or warehouse.

    • Prime Downtown Florence, SC location
    • Multiple bay doors for easy access and operations
    • Versatile space suitable for automotive, warehouse, or service‑related businesses
    • Abundant open space for vehicles, equipment, or flexible use
    • Dedicated office space for administrative functions
    Updated: Oct 11, 2025
    View details
    Retail Spaces in CrossRoads Center
    $18,134/Mo
    95,840 SF

    Retail Spaces in CrossRoads Center

    2522, 2524, 2528 David H McLeod Blvd, Florence, SC 29501

    Retail spaces available in high-traffic Florence commercial corridor.

    • High‑traffic location in Florence's main commercial corridor.
    • Convenient access to Interstate 20 and Interstate 95.
    • Located adjacent to Magnolia Mall.
    • Available spaces of ±18,134, ±34,430, and ±43,276 square feet.
    • Strong visibility to attract local residents and visitors.
    Updated: Apr 2
    View details
    Retail Space in Florence, SC
    Contact for pricing

    Retail Space in Florence, SC

    Located at a busy intersection with high visibility and access.

    Florence, SC 29501
    View details
    Retail Space in Regional Destination
    $22 SF/Yr
    2,800 SF

    Retail Space in Regional Destination

    Retail space available in premier shopping center, built in 2015.

    112-120 Woody Jones Blvd, Florence, SC
    View details
    Retail Space in Regional Destination
    $25 SF/Yr
    2,400 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination, built in 2015.

    104 Woody Jones Blvd, Florence, SC
    View details
    Retail Space in Florence, SC
    Contact for pricing
    8,000 SF

    Retail Space in Florence, SC

    8,000 SF retail space available for lease.

    2600 David H Mcleod Blvd, Florence, SC
    View details
    Florence Warehouse in West End
    Contact for pricing
    36,360 SF

    Florence Warehouse in West End

    Warehouse in Florence's West End District, near major retailers.

    2295 Hoffmeyer Rd, Florence, SC 29501
    View details
    Renovated Retail Space on US-52
    Contact for pricing
    22,800 SF

    Renovated Retail Space on US-52

    Anchor suite in renovated shopping center with high visibility.

    1611 S Irby St, Florence, SC 29505
    View details
    Retail Space in Regional Destination
    $22 SF/Yr
    4,475 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination near major highways.

    110 Woody Jones Blvd, Florence, SC
    View details
    Retail Space in Five Points
    Contact for pricing
    2,700 SF

    Retail Space in Five Points

    End-cap retail space in a high-traffic area for lease.

    1939 Hoffmeyer Rd, Florence, SC 29501
    View details
    Downtown Florence Mixed-Use Space
    Contact for pricing
    1,800 SF

    Downtown Florence Mixed-Use Space

    Prime mixed-use space in Downtown Florence Historic District.

    127 W Evans St, Florence, SC 29501
    View details
    Retail Space at Claussen Shops
    Contact for pricing
    3,600 SF

    Retail Space at Claussen Shops

    Grocery-anchored retail space for lease with ample parking.

    2332 Pamplico Hwy, Florence, SC 29505
    View details
    Florence Commercial Space For Rent
    Contact for pricing

    Florence Commercial Space For Rent

    Commercial space suitable for office, professional, or retail use.

    2843 W Palmetto Street Suite C, Florence, SC 29501
    View details
    Retail Outparcel in High-Traffic Area
    Contact for pricing

    Retail Outparcel in High-Traffic Area

    Outparcel for ground lease or build-to-suit in Florence, SC.

    500 2nd Loop Rd, Florence, SC 29505
    View details
    Established Commercial Complex on Second Loop
    Contact for pricing
    2,000 SF

    Established Commercial Complex on Second Loop

    Multi-tenant commercial complex with high visibility and convenient access.

    1800 2nd Loop Rd, Florence, SC 29501
    View details
    Prime Outparcel Opportunities in Florence
    Contact for pricing

    Prime Outparcel Opportunities in Florence

    Outparcels available at I-95 interchange, ideal for hotels, restaurants.

    2939 N Williston Rd, Florence, SC 29506
    View details
    Retail Space in Florence Mall
    Contact for pricing
    329,000 SF

    Retail Space in Florence Mall

    Prime retail space in regional shopping center, Florence, South Carolina.

    1945 W Palmetto St, Florence, SC 29501
    View details
    Based on your search, we've compiled 48 Potential Opportunities for your consideration. Besides 17 Active listings in Florence, SC, we suggest exploring alternatives. Similar 31 Properties for Sales.

    Similar Spaces for Sale in Florence, SC

    Consider Similar Space for Sale. We found 31 Spaces matching your search parameters.

    Remodeled Commercial Building Near Downtown
    $320,000
    2,165 SF

    Remodeled Commercial Building Near Downtown

    Turnkey commercial property in prime location with excellent visibility.

    910 W Evans st, Florence, SC 29501
    View details
    Historic Downtown Florence Commercial Building
    $2,700,000
    16,304 SF

    Historic Downtown Florence Commercial Building

    16,000 SF historic building in thriving downtown Florence.

    248-260 W Evans st., Florence, SC 29501
    View details
    Prime Commercial Property on Palmetto
    $250,000
    1,405 SF

    Prime Commercial Property on Palmetto

    High-visibility commercial property on a high-traffic street in Florence.

    2228 W Palmetto St., Florence, SC 29501
    View details
    Florence Commercial Building on Evans
    $79,000
    1,200 SF

    Florence Commercial Building on Evans

    Standalone building on Evans Street with redevelopment potential.

    617 W Evans St, Florence, SC 29501
    View details
    Turnkey Fish Market Opportunity
    $250,900
    2,499 SF

    Turnkey Fish Market Opportunity

    Profitable, equipped fish market for sale in Florence, SC.

    1401 W Darlington Street, Florence, SC 29501
    View details
    Versatile Commercial Parcel Near Downtown
    $499,900
    67,518 SF

    Versatile Commercial Parcel Near Downtown

    Office, showroom, and warehouse space less than one mile from Downtown.

    121 N Lawson St, Florence, SC 29501
    View details
    Former Convenience Store Investment Property
    $125,000
    2,400 SF

    Former Convenience Store Investment Property

    Fixer-upper retail property with 150' frontage, great investment potential.

    1134 E Howe Springs Road, Florence, SC 29505
    View details

    Florence, SC Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Florence, SC with 17 listings featured on our commercial real estate exchange. The current inventory includes 116,905 square feet of properties with an estimated lease value of $76 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Florence, SC begin at $2 SF/Yr, with an average of $15 SF/Yr and extend to $25 SF/Yr.
    List
    Map

    Popular Searches in Florence, SC

    Popular Categories

    Most Searched ZIP Codes in Florence, SC

    • 29501
    • 29505
    • 29506

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!