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    Lake City, SC
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    Lake City, SC Commercial Real Estate for Lease

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    Kingstree, SC Johnsonville, SC Florence, SC
    Retail Space in Lake City
    $12 SF/Yr
    1,200 SF
    Retail Space in Lake City

    252 Kelley St, Lake City, SC

    Retail spaces available in a busy Lake City shopping center.
    • Anchored by KJ’s IGA Grocery, Roses, Dollar Tree, Hibbetts, Cato, It’s Fashion, and Subway.
    • Located in the heart of Lake City.
    • 146,000 sf Retail strip center.
    • Available space: 22,000 sf at $3.00 rent rate (NNN).
    • Available space: 1200 sf at $12.00 rent rate (NNN).
    Updated: Jun 27, 2025
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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 1 Active listings in Lake City, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 12 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Restaurant Space with Drive-Thru
    Contact for pricing
    2,700 SF
    Restaurant Space with Drive-Thru

    2,700 SF restaurant space with existing drive-thru.

    1104 Pamplico Highway, Florence, SC 29505

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    146,270 SF Industrial Warehouse
    Contact for pricing
    146,270 SF
    146,270 SF Industrial Warehouse

    Industrial warehouse with versatile use options and strategic prime location.

    729 White Oak Dr, Johnsonville, SC 29555

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    Industrial Warehouse with Rail Access
    Contact for pricing
    146,270 SF
    Industrial Warehouse with Rail Access

    146,270 sq ft warehouse for lease near rail line.

    729 White Oak Dr, Johnsonville, SC 29555

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    New Office Space Available
    $26 SF/Yr
    3,600 SF
    New Office Space Available

    Shell space in a new building, build-out to suit.

    609 2nd Loop Rd, Florence, SC 29505

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    Similar Spaces for Sale in Lake City, SC

    Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

    78.4 Acres Farmland with Home
    $515,000
    1,376 SF
    78.4 Acres Farmland with Home

    78.4 acres featuring cropland, wetlands, and a 1,376-SF home.

    711 Cade Rd., Lake City, SC 29560

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    Prime Commercial Land Opportunity
    $599,000
    2.90 Acres
    Prime Commercial Land Opportunity

    2.9-acre commercial site in Lake City, SC.

    791 S Ron McNair Blvd., Lake City, SC 29560

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    Corner Commercial Development Lot
    $59,900
    1,200 SF
    Corner Commercial Development Lot

    Corner commercial lot on a major route between Florence and Charleston, suited for office, retail, or restaurant development.

    360 S Ron McNair Blvd, Lake City, SC 29560

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    Prime Commercial Site on Highway
    $599,000
    2.90 Acres
    Prime Commercial Site on Highway

    Development opportunity in high-traffic commercial corridor near industrial area.

    791 S Ron McNair Blvd, Lake City, SC 29560

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    Lake City Commercial Parking Lot
    $160,000
    0.47 Acres
    Lake City Commercial Parking Lot

    0.47 acre commercial lot with rental income potential.

    0.47 Acres-TBD Sumter St., Lake City, SC 29560

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    Former Talon Zipper Plant
    $1,474,350
    105,000 SF
    Former Talon Zipper Plant

    Manufacturing/warehouse space on 20 acres near airport runway.

    701 South Ron McNair Boulevard |, Lake City, SC 29560

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    Downtown Lake City Commercial Building
    $199,000
    2,500 SF
    Downtown Lake City Commercial Building

    2,500 sq ft commercial building in downtown Lake City.

    112 E Main St, Lake City, SC 29560

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    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF
    Stand-Alone Office Building For Sale

    Stand-alone office building with immediate occupancy in Lake City, SC.

    215 John St, Lake City, SC

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    Commercial Lot in Downtown
    $59,900
    1,200 SF
    Commercial Lot in Downtown

    Commercial lot in a high-traffic downtown location.

    360 S Ron McNair Blvd, Lake City, SC 29560

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    Lake City Industrial Warehouse
    $5,900,000
    157,800 SF
    Lake City Industrial Warehouse

    Industrial warehouse property available for sale in Lake City.

    1051 E Main St, Lake City, SC

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    Vacant Restaurant with Drive-Thru
    $850,000
    2,819 SF
    Vacant Restaurant with Drive-Thru

    2,819 SF vacant restaurant with drive-thru for sale.

    147 S Ron McNair Blvd, Lake City, SC 29560

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    Commercial Land with Development Potential
    $200,000
    1.50 Acres
    Commercial Land with Development Potential

    Commercial land with frontage on US 52, development potential.

    356 S Ron McNair Blvd, Lake City, SC 29560

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    Lake City, SC Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Lake City, SC with 1 listings featured on our commercial real estate exchange. The current inventory includes 1,200 square feet of properties with an estimated lease value of $12 SF/Yr.

    Estimated lease rates for Commercial real estate in Lake City, SC begin at $12 SF/Yr, with an average of $12 SF/Yr and extend to $12 SF/Yr.
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