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    Lake City, SC Office Properties & Spaces for Sale

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    Columbia, SC Aiken, SC Greenville, SC
    Downtown Lake City Commercial Building
    $199,000
    2,500 SF

    Downtown Lake City Commercial Building

    112 E Main St, Lake City, SC 29560

    2,500 sq ft commercial building in downtown Lake City.

    • Prime Main Street location in downtown Lake City, SC
    • 2,500 sq ft commercial building suitable for various business concepts
    • Existing built‑in bar, ideal for restaurant,
    Updated: Mar 24
    View details
    Stand-Alone Office Building For Sale
    $250,000
    1,722 SF

    Stand-Alone Office Building For Sale

    215 John St, Lake City, SC

    Stand-alone office building with immediate occupancy in Lake City, SC.

    • Stand‑alone ±1722 SF building offers independence and privacy.
    • Immediate occupancy available.
    • Includes two large open rooms, two private offices, a breakroom, and two ADA restrooms.
    • Fenced parking area provides security and convenience.
    • ±.286 acre lot within Lake City limits.
    Updated: Feb 12, 2025
    View details
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 2 Active listings in Lake City, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Olanta Commercial Building on US 301
    $60,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114
    View details
    McLeod Physician Associates For Sale
    $1,384,320
    2,666 SF

    McLeod Physician Associates For Sale

    2,666 SF medical office in Florence, SC for sale.

    1540 American Dr, Florence, SC
    View details
    Olanta Commercial Building on US 301
    $60,000
    1,500 SF

    Olanta Commercial Building on US 301

    Commercial building in Olanta, SC, with multiple business possibilities.

    405 N Jones Road, Olanta, SC 29114
    View details
    Medical Office Building Near MUSC
    $2,200,000
    7,950 SF

    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.

    1929 Mountain Laurel Court, Florence, SC
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Downtown Lake City Commercial Lot
    $59,900
    1,200 SF

    Downtown Lake City Commercial Lot

    Commercial lot in downtown Lake City, South Carolina.

    360 S Ron McNair Blvd, Lake City, SC 29560
    View details
    Cleared Commercial Lot in Kingstree
    $275,000
    2.00 Acres

    Cleared Commercial Lot in Kingstree

    2-acre commercial lot on N Williamsburg County Highway, Kingstree, SC.

    2 Acres-TBD N Williamsburg County Hwy., Kingstree, SC 29556
    View details
    Commercial Lot in Kingstree, SC
    $50,000
    0.08 Acres

    Commercial Lot in Kingstree, SC

    Commercial property in the heart of Kingstree, South Carolina.

    211 E Main St., Kingstree, SC 29556
    View details
    Commercial Lot in Hemingway, SC
    $185,000
    1.80 Acres

    Commercial Lot in Hemingway, SC

    Spacious commercial lot ready to build in downtown Hemingway.

    312 E Broad St., Hemingway, SC 29554
    View details

    Explore Off-Market Properties in Lake City, SC

    Consider similar Off-Market properties in Lake City, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    221 Rodgers Ave

    221 Rodgers Ave

    OFFICE BUILDING • 2,929 SF
    Value Estimation by Request
    221 Rodgers Ave, Lake City, SC 29560-2151
    View details
    130 Acline St

    130 Acline St

    MEDICAL BUILDING • 2,052 SF
    Value Estimation by Request
    130 Acline St, Lake City, SC 29560-2633
    View details
    925 Main St

    925 Main St

    OFFICE BUILDING • 2,100 SF
    Value Estimation by Request
    925 Main St, Lake City, SC 29560
    View details
    889 Matthews Rd

    889 Matthews Rd

    OFFICE BUILDING • 1,725 SF
    Value Estimation by Request
    889 Matthews Rd, Lake City, SC 29560-7025
    View details
    121 Main St

    121 Main St

    OFFICE BUILDING • 1,680 SF
    Value Estimation by Request
    121 Main St, Lake City, SC 29560-2626
    View details
    231 Kelley St

    231 Kelley St

    OFFICE BUILDING • 11,000 SF
    Value Estimation
    $1,420,000
    231 Kelley St, Lake City, SC 29560-2446
    View details
    110 Morris St

    110 Morris St

    OFFICE BUILDING • 3,411 SF
    Value Estimation by Request
    110 Morris St, Lake City, SC 29560-2420
    View details
    331 Elizabeth Anne Ct

    331 Elizabeth Anne Ct

    MEDICAL BUILDING • 7,920 SF
    Value Estimation
    $1,905,000
    331 Elizabeth Anne Ct, Lake City, SC 29560-2488
    View details
    154 Main St, Unit 1

    154 Main St, Unit 1

    OFFICE BUILDING • 1,825 SF
    Value Estimation by Request
    154 Main St, Lake City, SC 29560-2426
    View details
    312 Morris St

    312 Morris St

    OFFICE BUILDING • 1,297 SF
    Value Estimation by Request
    312 Morris St, Lake City, SC 29560-3232
    View details
    107 Ron Mcnair Blvd

    107 Ron Mcnair Blvd

    OFFICE BUILDING • 1,056 SF
    Value Estimation by Request
    107 Ron Mcnair Blvd, Lake City, SC 29560-3265
    View details
    325 Mercy St

    325 Mercy St

    MEDICAL BUILDING • 5,461 SF
    Value Estimation by Request
    325 Mercy St, Lake City, SC 29560-2331
    View details
    115 Matthews Rd

    115 Matthews Rd

    MEDICAL BUILDING • 1,588 SF
    Value Estimation by Request
    115 Matthews Rd, Lake City, SC 29560-2309
    View details
    103 Main St

    103 Main St

    OFFICE BUILDING • 988 SF
    Value Estimation by Request
    103 Main St, Lake City, SC 29560-2626
    View details
    144 Main St

    144 Main St

    OFFICE BUILDING • 949 SF
    Value Estimation by Request
    144 Main St, Lake City, SC 29560-2426
    View details
    261 Kelley St

    261 Kelley St

    OFFICE BUILDING • 3,872 SF
    Value Estimation by Request
    261 Kelley St, Lake City, SC 29560-2450
    View details
    101 John St

    101 John St

    OFFICE BUILDING • 6,220 SF
    Value Estimation
    $585,000
    101 John St, Lake City, SC 29560-2411
    View details
    108 Sauls St

    108 Sauls St

    OFFICE BUILDING • 1,650 SF
    Value Estimation by Request
    108 Sauls St, Lake City, SC 29560-2631
    View details
    630 Old Georgetown Rd

    630 Old Georgetown Rd

    OFFICE BUILDING • 12,887 SF
    Value Estimation
    $840,000
    630 Old Georgetown Rd, Lake City, SC 29560-6407
    View details
    276 Ron Mcnair Blvd

    276 Ron Mcnair Blvd

    MEDICAL BUILDING • 8,990 SF
    Value Estimation
    $845,000
    276 Ron Mcnair Blvd, Lake City, SC 29560-2462
    View details
    207 John St

    207 John St

    OFFICE BUILDING • 2,308 SF
    Value Estimation by Request
    207 John St, Lake City, SC 29560-2413
    View details
    416 Main St

    416 Main St

    OFFICE BUILDING • 1,056 SF
    Value Estimation by Request
    416 Main St, Lake City, SC 29560-2369
    View details

    Lake City, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 72 office properties & spaces for sale in Lake City, SC on our real estate platform. These investment opportunities span a total of 4,222 square feet of properties for sale, with an estimated market value of $449,000.

    Sale prices for office spaces in Lake City, SC start at $199,000, averaging $224,500, and reaching up to $250,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Lake City, SC

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