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Spartanburg County, SC Office Spaces for Sale

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56 properties
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Downtown Office Building
Updated: Jul 29
Downtown Office Building

300 S Daniel Morgan Avenue, Spartanburg, SC 29306

$2,500,000
24,000 sqft 2.18 AC lot
24,000‑square‑foot office building
Situated on a 2.18‑acre tract
Downtown Spartanburg location
Central air conditioning
Concrete flooring
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Office Building Under Renovation
Updated: Jul 17
Office Building Under Renovation

180 John B White Sr Boulevard, Spartanburg, SC 29306

$525,000
2,664 sqft 0.23 AC lot
Interior renovation currently underway
Approximately 0.23‑acre site
Paved parking included
Road frontage on John B. White Sr Boulevard
Central air conditioning
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Mixed-Use Property with Basement
Mixed-Use Property with Basement

1504 E Rutherford Street, Landrum, SC 29356

$449,000
1,875 sqft 1.59 AC lot

Brick ranch-style building with flexible commercial and residential use potential in a central downtown setting.

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See what stands out in Spartanburg County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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Flex Space Under Renovation
Flex Space Under Renovation

180 John B White Sr Blvd, Spartanburg, SC 29306

$525,000
2,664 sqft 0.23 AC lot

Adaptable commercial building with paved parking and access to a heavily traveled business corridor.

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Two-Story Office Building
Two-Story Office Building

275 E henry Street, Spartanburg, SC 29306

$365,000
1,450 sqft 0.23 AC lot

Leased ground-floor space accompanies an available upper-level office or studio area for owner occupancy or additional leasing.

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Flex Building with Heated Garage
Flex Building with Heated Garage

250 Cedar Springs Avenue, Spartanburg, SC 29302

$269,999
0.46 AC lot

Interior includes office rooms, a heated garage, lounge, kitchen area, and multiple bathrooms.

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Brick Downtown Mixed-Use Property
Brick Downtown Mixed-Use Property

1504 E Rutherford Street, Landrum, SC 29356

$449,000
1.59 AC lot

C-2 zoning and dual-street frontage support residential, office, business, or mixed-use applications.

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Medical Office Building
Medical Office Building

1250 John B White Sr Boulevard, Spartanburg, SC 29306

$1,295,000
6,875 sqft

Medical office space offered for sale in Spartanburg.

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Street-Level Flex Space
Street-Level Flex Space

516 E Main Street, Spartanburg, SC 29302

$316,500
2,125 sqft 0.04 AC lot

Multi-room commercial building supports retail, professional office, and service-oriented uses.

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Mixed-Use Commercial Building
Mixed-Use Commercial Building

180 John B White Sr Boulevard, Spartanburg, SC 29306

$525,000
0.23 AC lot

Interior renovation is underway in a versatile commercial building with paved parking.

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Office Property with Finished Basement
Office Property with Finished Basement

850 Falling Creek Rd, Spartanburg, SC 29301

$380,000
1,879 sqft 0.50 AC lot

Versatile office building includes a large meeting space, finished basement storage, and a commercial kitchen on a half-acre lot.

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Flex Space with Heated Garage
Flex Space with Heated Garage

250 Cedar Springs Avenue, Spartanburg, SC 29302

$269,999
3,445 sqft 0.46 AC lot

Versatile commercial building with office, garage, kitchen, lounge, storage, and paved parking areas.

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Commercial Land with Redevelopment Potential
Commercial Land with Redevelopment Potential

352 Whitney Road, Spartanburg, SC 29303

$74,900
925 sqft 0.40 AC lot

Commercially zoned parcel with an existing structure requiring extensive renovation and public water service.

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Flex Building with Heated Garage
Flex Building with Heated Garage

250 Cedar Springs Ave, Spartanburg, SC 29302

$269,999
3,445 sqft

Flexible commercial building with office areas, restrooms, kitchen space, storage, and paved parking.

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Remodeled Office Building with Drive-Thru
Remodeled Office Building with Drive-Thru

8715 Asheville Hwy, Boiling Springs, SC 29316

$525,000
2,200 sqft 0.47 AC lot

Commercial office property with multiple private rooms, customer-oriented drive-thru access, and rear gravel parking.

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Flex Space With Office Layout
Flex Space With Office Layout

516 E Main St, Spartanburg, SC 29302

$316,500
2,125 sqft

Adaptable commercial building with offices, open work areas, reception, restrooms, and street-level access.

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Two-Story Office Building with Income
Two-Story Office Building with Income

275 E Henry St, Spartanburg, SC 29306

$365,000
1,450 sqft

Income-producing office building with a leased first floor and vacant second-floor office or studio space.

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Spartanburg Office Building For Sale
Spartanburg Office Building For Sale

130 Dillon Drive, Spartanburg, SC 29307

$1,450,000
7,200 sqft

7,200 SF office building near Spartanburg Medical District.

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Multi-Office Building
Multi-Office Building

858 E Main St, Spartanburg, SC 29301

$369,000
2,500 sqft

Office property in Spartanburg’s business district with on-site parking and a flexible multi-office layout.

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Remodeled Office Building
Remodeled Office Building

100 Inman Rd, Lyman, SC 29365

$1,200,000
2,662 sqft

Configured with private offices, workstations, and a dedicated conference room.

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Office and Retail Flex Building
Office and Retail Flex Building

516 E Main Street, Spartanburg, SC 29302

$316,500
2,100 sqft

Street-level reception plus multiple offices and flex spaces, positioned on a high-traffic corridor with 25,000+ vehicles daily.

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Limited Office District Office Building
Limited Office District Office Building

1423 JOHN B WHITE SR BLVD, Spartanburg, SC 29306

Contact for pricing
2,692 sqft 0.61 AC lot

A 2,692± SF office on 0.61± acres with 200± road frontage, high visibility, and LOD zoning for qualified uses.

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Medical Office Building with Parking
Medical Office Building with Parking

1776 Skylyn Dr, Spartanburg, SC 29307

Contact for pricing
11,832 sqft

Medical office building with numerous exam, treatment, and procedure rooms and ample on-site parking.

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All-Brick Medical Office Building
All-Brick Medical Office Building

108 W Rutherford St, Landrum, SC 29356

Contact for pricing
2,400 sqft

All-brick medical office building with exam rooms, multiple lobbies and reception areas, and private parking.

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Spartanburg County, SC Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Spartanburg County, SC, showcased through 56 active listings on our real estate platform. These investment opportunities span a total of 219,982 square feet of properties for sale, with an estimated market value of $13,621,297.

Sale prices for office spaces in Spartanburg County, SC start at $74,900, averaging $567,554, and reaching up to $2,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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